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Search Results: 1 - 10 of 48664 matches for " SHAO Fu-dong "
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Research and implementation of program condition visualization based on AOP
基于AOP的程序状态可视化方法研究与实现

SHAO Fu-dong,LIU Xiao-dong,YANG Bao-ming,
邵付东

计算机应用 , 2006,
Abstract: This paper described the concept of Aspect Oriented Programming(AOP) and its advantages of solving crosscutting concerns, discussed its application in the field of program condition visualization and presented an example of program condition visualization in the program of Evaluation of Expression by using AOP technology. The function of program condition visualization usually appears as crosscutting concern. Compared with Object Oriented Programming(OOP)technology, AOP technology provides a more loose-couple approach to modularize crosscutting concerns.
On adjustment of the rural energy development policy in China
我国农村能源发展方针调整问题探讨

ZHAI,Fu-dong,
翟辅东

自然资源学报 , 2003,
Abstract: 我国农村能源发展方针是“因地制宜,多能互补,综合利用,讲求效益”,这是在短缺经济的背景下,针对能源危机而提出来的。目前我国农村的社会、经济及其能源供需结构形势发生了重大变化,大量商品能进入农村市场,农村能源面临着结构升级和如何现代化的问题,原十六字方针因缺少生态观和市场观,已不符合现时和未来农村能源可持续发展的实际。章提出了农村能源发展的十八字方针“因地制宜,生态兴能,市场调节,讲求综合效益”,并逐一对新方针中的论点进行了阐述,提出了我国应以生物二次能源与商品能源整合的可持续能源的发展理念,提出了实施新方针的有关举措。
Inflammation-Mediated Memory Dysfunction and Effects of a Ketogenic Diet in a Murine Model of Multiple Sclerosis
Do Young Kim, Junwei Hao, Ruolan Liu, Gregory Turner, Fu-Dong Shi, Jong M. Rho
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0035476
Abstract: A prominent clinical symptom in multiple sclerosis (MS), a progressive disorder of the central nervous system (CNS) due to heightened neuro-inflammation, is learning and memory dysfunction. Here, we investigated the effects of a ketogenic diet (KD) on memory impairment and CNS-inflammation in a murine model of experimental autoimmune encephalomyelitis (EAE), using electrophysiological, behavioral, biochemical and in vivo imaging approaches. Behavioral spatial learning deficits were associated with motor disability in EAE mice, and were observed concurrently with brain inflammation. The KD improved motor disability in the EAE model, as well as CA1 hippocampal synaptic plasticity (long-term potentiation) and spatial learning and memory (assessed with the Morris Water Maze). Moreover, hippocampal atrophy and periventricular lesions in EAE mice were reversed in KD-treated EAE mice. Finally, we found that the increased expression of inflammatory cytokines and chemokines, as well as the production of reactive oxygen species (ROS), in our EAE model were both suppressed by the KD. Collectively, our findings indicate that brain inflammation in EAE mice is associated with impaired spatial learning and memory function, and that KD treatment can exert protective effects, likely via attenuation of the robust immune response and increased oxidative stress seen in these animals.
Nicotinic Receptor β2 Determines NK Cell-Dependent Metastasis in a Murine Model of Metastatic Lung Cancer
Junwei Hao, Fu-Dong Shi, Mohammed Abdelwahab, Samuel X. Shi, Alain Simard, Paul Whiteaker, Ronald Lukas, Qinghua Zhou
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0057495
Abstract: Cigarette smoke exposure markedly compromises the ability of the immune system to protect against invading pathogens and tumorigenesis. Nicotine is a psychoactive component of tobacco products that acts as does the natural neurotransmitter, acetylcholine, on nicotinic receptors (nAChRs). Here we demonstrate that natural killer (NK) cells strongly express nAChR β2. Nicotine exposure impairs the ability of NK cells to kill target cells and release cytokines, a process that is largely abrogated by nAChR β2 deficiency. Further, nicotinic suppression of NF-κB-induced transcriptional activity in NK cells is dependent on nAChR β2. This nAChR subtype also plays a large role in the NK cell-mediated control of melanoma lung metastasis, in a murine lung metastasis model exposed to nicotine. Our findings suggest nAChR β2 as a prominent pathway for nicotine induced impairment of NK cell functions which contributes to the occurrence of smoking-related pathologies.
RESEARCH ON SWELLING AND STRAIN SOFTENING MODEL OF SWELLING ROCK IN HONGSHANYAO
红山窑膨胀岩的膨胀和软化特性及模型研究

ZHU Zhen-de,ZHANGAi-jun,XING Fu-dong,
朱珍德
,张爱军,邢福东

岩石力学与工程学报 , 2005,
Abstract: 以南京红山窑水利枢纽工程所提供的岩基红砂岩岩芯为例,采用MTS815.02型岩石刚性伺服试验系统和岩石膨胀测量仪,对风化红砂岩进行膨胀变形及力学特性试验研究。试验结果表明,红砂岩膨胀应变随吸水率增加而呈对数形增长。由于吸水率的变化,膨胀岩的弹性模量、泊松比和屈服极限等力学性能都将发生变化,即所谓软化现象,从而膨胀应力、塑性流动以及随湿度场而变化的屈服准则等都是相互耦合的。基于试验结果,提出考虑膨胀岩膨胀及软化特性的弹塑性本构模型。
Centrally Administered Pertussis Toxin Inhibits Microglia Migration to the Spinal Cord and Prevents Dissemination of Disease in an EAE Mouse Model
Jun-xiang Yin,Jiang-long Tu,Hao-jie Lin,Fu-dong Shi,Ru-lan Liu,Chong-bo Zhao,Stephen W. Coons,Sandra Kuniyoshi,Jiong Shi
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0012400
Abstract: Experimental autoimmune encephalomyelitis (EAE) models are important vehicles for studying the effect of infectious elements such as Pertussis toxin (PTx) on disease processes related to acute demyelinating encephalomyelitis (ADEM) or multiple sclerosis (MS). PTx has pleotropic effects on the immune system. This study was designed to investigate the effects of PTx administered intracerebroventricularly (icv) in preventing downstream immune cell infiltration and demyelination of the spinal cord.
EXPERIMENTAL STUDIES AND MICROCOSMIC MECHANICS ANALYSIS ON MARBLE RUPTURE UNDER HIGH CONFINING PRESSURE AND HIGH HYDRAULIC PRESSURE
高围压高水压条件下大理岩断口微观机理分析与试验研究

ZHU Zhen-de,ZHANG Yong,XU Wei-ya,XING Fu-dong,WANG Si-jing,
朱珍德
,张 勇,徐卫亚,邢福东,王思敬

岩石力学与工程学报 , 2005,
Abstract: 为了探讨高围压高水压对大理岩变形、强度、脆–塑转化特性及破坏断裂损伤劣化的影响,取锦屏二级水电站引水隧洞大理岩分别进行高水压、高围压、低围压作用下全应力–应变过程三轴压缩对比试验,然后,对大理岩破坏断裂断口进行微观电镜扫描试验,分析不同工况条件下大理岩断口微观形貌特征。试验结果表明,在低围压作用下莫尔强度包络线近似为线性的,在高围压作用下莫尔强度包络线是非线性的。高水压力的存在抑制岩石脆性向塑性的发展,降低岩石的强度,同时对软化区裂纹的扩展、贯通起到加剧作用。通过微观数字图像试验分析发现,高围压条件下大理岩断口裂纹长度小、密度大、分布相对均匀,给出高水压高围压作用下岩石破裂产生的微观损伤力学机理,为进一步分析高围压高内外水压条件下非圆形洞室围岩失稳破坏机理提供了可靠的试验依据。
TESTING STUDY ON THE SWELLING MECHANICAL BEHAVIOR OF RED SANDSTONE
红砂岩膨胀力学特性试验研究

ZHU Zhen-de,XING Fu-dong,LIU Han-long,WANG Si-jing,
朱珍德
,邢福东,刘汉龙,王思敬

岩石力学与工程学报 , 2005,
Abstract: A series of tests are performed on rock rigidity servo testing system (MTS815.02) and rock odometer to study the swelling mechanical behaviors of red sandstone taken from the foundation pit of Hongshanyao Project (HSYP) in Nanjing. The interrelation of expansive force with water absorption rate and the law of expansive force with expansive strain are studied. It is concluded that the water absorption rate has a significant influence on expansive force.
北淮阳地区与斑岩型钼矿床相关岩浆岩的地质地球化学特征及成因
Geological and geochemical characteristics and genesis of magmatic rocks related to porphyry Mo deposits in the Beihuaiyang region.

王波华, 张怀东, 王 萍, 徐晓春, 郝越进
WANG Bei-Hua
, ZHANG Fu-Dong, WANG Ping, XU Xiao-Chun, HAO Huo-Jin

- , 2016, DOI: 10.13745/j.esf.2016.04.004
Abstract: 位于秦岭—大别造山带东段的北淮阳地区分布有众多的斑岩型钼矿床,其成矿与岩浆作用紧密相关。对该区与斑岩型钼矿床密切相关的岩浆岩进行了系统的岩石化学、微量元素和同位素地球化学研究,深入探讨了其成因。研究认为,成矿岩体规模较小,岩性为花岗(斑)岩类,受北东向与北西向区域性断裂的次级构造控制。岩石化学成分以高硅、高钾、富碱为特征,为高钾钙碱性钾玄岩系列、准铝过铝质岩石。岩石微量、稀土元素特征相似并显示壳源特征。岩石Sr Nd Pb Hf同位素地球化学特征显示这些花岗质岩浆与整个大别地区白垩纪花岗岩的成岩物质来源一致,源于新元古界北大别片麻岩和扬子克拉通北缘TTG型岩浆,并混入一些古元古代扬子克拉通古老地壳物质(如崆岭杂岩)。在白垩纪发生的下地壳拆沉、软流圈上涌及大规模地壳伸展等机制下,扬子克拉通北缘的地壳熔融并提供了主要的成岩物质,幔源岩浆的上涌可能提供了热源,其物质的加入是次要的。该区与斑岩型钼矿床相关岩浆岩与东秦岭地区类似,属深源浅成型花岗岩类。
An improved impulsive control approach to nonlinear systems with time-varying delays

Zhang Hua-Guang,Fu Jie,Ma Tie-Dong,Tong Shao-Cheng,

中国物理 B , 2009,
Abstract: A scheme for the impulsive control of nonlinear systems with time-varying delays is investigated in this paper. Based on the Lyapunov-like stability theorem for impulsive functional differential equations (FDEs), some sufficient conditions are presented to guarantee the uniform asymptotic stability of impulsively controlled nonlinear systems with time-varying delays. These conditions are more effective and less conservative than those obtained. Finally, two numerical examples are provided to demonstrate the effectiveness of the proposed method.
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