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Search Results: 1 - 10 of 2595 matches for " SATA YOSHIDA SRIE RAHAYU "
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Nucleus Pearl Coating Process of Freshwater Mussel Anodonta woodiana (Unionidae)
HAYATI Journal of Biosciences , 2013,
Abstract: The limiting factor which is a weakness of sea water pearl production are high costs, the risk of major business failures and a long coating time. From the issue of freshwater pearls appear to have prospects of alternative substitution for sea water pearl. This present study aimed to evaluate effect of loads (the number and diameter nucleus) on freshwater pearl coating process and the number and size of the appropriate nucleus diameter, to produce the optimum coating thickness of half-round pearls. The research consists of experimental implantation of 2, 4, and 6 nucleus number per individual mussel was maintained by the method stocked in hapa in bottom waters. Observation method and factorial randomized block design used in the study of the influence of the load to the successfulness of pearl coating and the pearl layer thickness. The results showed that A. woodiana can be utilized as a producer of freshwater pearls. In addition, the number of optimum nucleus that can be attached to the mussel A. woodiana was 2 grains/individuals with a diameter of 10 mm. Shells implanted with the optimum nucleus diameter and number of pearls produced the highest layer thickness of 17 m after 9 months cultivation. This result was good enough compared with the layer thickness of sea water pearl production after the same cultivation time.
Feeding Rate of Soil Animals in Different Ecosystems in Pati, Indonesia
HAYATI Journal of Biosciences , 2006,
Abstract: The feeding activity of soil animals was measured by using bait lamina test in three main ecosystems, i.e. the teak forest, home garden and rainfed paddy field. Two additional ecosystems in rainfed paddy field, i.e. the old (permanently established bund around paddy fields) and new bunds were examined as well. Three blocks of bait-lamina sticks (each block consisting of 16 individual sticks) were exposed at each location. The bait lamina were retrieved from the soil after two days and visually assessed. Each hole is designated as “fed” (perforated) or “non-fed” hole. The feeding rate is measured as the absolute number of “fed” holes. Soil animals in the old bunds showed the highest feeding activity (55.20%), followed by home garden (39.10%), rainfed paddy field (16.50%), teak forest (15.60%), and new bund (7.80%). The frequency of animals attack to the bait strips also indicated the similar pattern as their feeding activity, i.e. high in the old bunds (0.90), followed by home garden (0.70), teak forest (0.40), new bunds (0.40) and rainfed paddy field (0.30), respectively.
Rahayu, L.
Jurnal Biologi el-Hayah , 2009,
Abstract: Penelitian penggunaan chitosan dengan konsentrasi yang berbeda sebagai larutan perendaman daging ayam broiler selama 5 menit serta penyimpanan 8 jam telah dilakukan untuk mengetahui pengaruhnya terhadap total mikroba dan nilai TVBN. Hasil penelitian menunjukkan bahwa perendaman daging ayam dalam larutan chitosan dengan konsentrasi yang berbeda berpengaruh nyata (P<0,05) terhadap total mikroba, dan tidak berpengaruh terhadap nilai TVBN. Setelah penyimpanan 8 jam daya hambat total mikroba yang paling tinggi yaitu konsentrasi 2% sebesar 4,4 x 106 CFU/g.
Species diversity of the Genus Hoya (Asclepiadaceae) in Bukit Batikap Sanctuary Forest, Central Kalimantan
Biodiversitas , 2006,
Abstract: The Genus Hoya (Apocynaceae: Asclepiadoideae) is being appreciated as exotic ornamental plant in Europe, USA and Australia, while in Indonesia as the country of origin still neglected. Indonesia was predicted have the highest Hoya species diversity (about 60 species from 150 species in the world). Among the major Islands in Indonesia, Kalimantan was predicted have the highest diversity in Hoya species. The inventory of the species has been done in the Bukit Batikap Sanctuary Forest, Muller Mountain in Central Kalimantan. Nine Hoya species of about thirties species in Kalimantan were found in Bukit Batikap, namely: H. coronaria Blume, H. cf. erythrostemma Kerr., H. latifolia G. Don., H. mitrata Kerr., H. nummularioides Const., H. pusilla Rintz, H. revoluta Wight, H. scortechinii King & Gamble, and Hoya cf. vaccinioides Hook.f.
Nita Rahayu
Bulletin of Health Research , 2012,
Eicosapentaenoic Acid Supplementation Changes Fatty Acid Composition and Corrects Endothelial Dysfunction in Hyperlipidemic Patients
Ken Yamakawa,Michio Shimabukuro,Namio Higa,Tomohiro Asahi,Kageyuki Ohba,Osamu Arasaki,Moritake Higa,Yoshito Oshiro,Hisashi Yoshida,Tohru Higa,Taro Saito,Shinichiro Ueda,Hiroaki Masuzaki,Masataka Sata
Cardiology Research and Practice , 2012, DOI: 10.1155/2012/754181
Abstract: We investigated the effects of purified eicosapentaenoic acid (EPA) on vascular endothelial function and free fatty acid composition in Japanese hyperlipidemic subjects. In subjects with hyperlipidemia (total cholesterol ?mg/dL and/or triglycerides ?mg/dL), lipid profile and forearm blood flow (FBF) during reactive hyperemia were determined before and 3 months after supplementation with 1800?mg/day EPA. Peak FBF during reactive hyperemia was lower in the hyperlipidemic group than the normolipidemic group. EPA supplementation did not change serum levels of total, HDL, or LDL cholesterol, apolipoproteins, remnant-like particle (RLP) cholesterol, RLP triglycerides, or malondialdehyde-modified LDL cholesterol. EPA supplementation did not change total free fatty acid levels in serum, but changed the fatty acid composition, with increased EPA and decreased linoleic acid, γ-linolenic acid, and dihomo-γ-linolenic acid. EPA supplementation recovered peak FBF after 3 months. Peak FBF recovery was correlated positively with EPA and EPA/arachidonic acid levels and correlated inversely with dihomo-γ-linolenic acid. EPA supplementation restores endothelium-dependent vasodilatation in hyperlipidemic patients despite having no effect on serum cholesterol and triglyceride patterns. These results suggest that EPA supplementation may improve vascular function at least partly via changes in fatty acid composition. 1. Background Consumption of fish or fish oil is inversely correlated with morbidity and mortality due to cardiovascular disease [1–5]. The major components of fish oils are long-chain n-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), which may have cardioprotective potential. Supplementation with purified EPA ethyl ester was shown to lower major coronary events in Japanese hypercholesterolemic patients (Japan EPA Lipid Intervention Study: JELIS) [6, 7]. Addition of 1800?mg/day EPA to low-dose statin treatment reduced the incidence of primary cardiovascular endpoints. In the JELIS study, the benefits of EPA were greater in patients with a prior history of coronary artery disease (CAD) (secondary prevention) [6] and in patients with multiple coronary risk factors [7]. Interestingly, such benefits were obtained without an effect of lowering low-density lipoprotein cholesterol (LDL-C) levels, but were more pronounced in populations consuming low amounts of n-3 fatty acids. However, the LDL-C-independent mechanism(s) of this phenomenon have not yet been clarified [6, 7]. A variety of EPA actions such as antithrombotic [8,
Analysis of the factors motivating HCV-infected patients to accept interferon therapy
Yumiko Nagao, Michio Sata
BMC Research Notes , 2012, DOI: 10.1186/1756-0500-5-470
Abstract: A total of 94 HCV-infected patients who were admitted to our hospital for IFN therapy were asked questions regarding their motivation to accept IFN therapy and were investigated for the presence of oral lichen planus (OLP) before and during IFN treatment. Recommendation and encouragement from other people were the most common factors motivating the acceptance of IFN therapy (49/94, 52.13%). The other motivators were independent decision (30.85%), economic reasons (5.32%), and others. According to multivariate analysis, three factors – sex (male), retreatment after previous IFN therapy, and independent decision to accept IFN therapy - were associated with patients after curative treatment of hepatocellular carcinoma (HCC). The adjusted odds ratios for these three factors were 26.06, 14.17, and 8.72, respectively. The most common oral mucosal lesions included OLP in 11 cases (11.70%). One patient with OLP had postoperative squamous cell carcinoma of the tongue. The rate of sustained virological response (SVR) was 45.45% in cases with OLP and 54.55% in cases without OLP. There were no patients who discontinued IFN therapy because of side effects such as oral mucosal diseases.We should give full explanation and recommend a course of treatment for a patient to accept IFN therapy. The system to support liver disease as well as oral diseases is also necessary for patient treated for IFN therapy.Japanese hepatitis C virus (HCV)-infected patients tend to be older than those in other countries and their older age favors the onset of hepatocellular carcinoma (HCC), leading to an increased mortality rate [1,2]. The number of deaths from HCC continues to rise in Japan, where about 80% of HCC are caused by HCV and 10% by hepatitis B virus (HBV) [1,2].Interferon (IFN) therapy for chronic hepatitis C is the only treatment that enables complete elimination of the virus. In recent years, pegylated IFN (Peg-IFN) and ribavirin (RBV) combination therapy has been the standard treatment f
A retrospective case-control study of hepatitis C virus infection and oral lichen planus in Japan: association study with mutations in the core and NS5A region of hepatitis C virus
Yumiko Nagao, Michio Sata
BMC Gastroenterology , 2012, DOI: 10.1186/1471-230x-12-31
Abstract: In this retrospective study, 59 patients (group 1-A) with oral lichen planus among 226 consecutive patients who visited our hospital and 85 individuals (group 1-B, controls) with normal oral mucosa were investigated for the presence of liver disease and HCV infection. Risk factors for the presence of oral lichen planus were assessed by logistic regression analysis. We compared aa substitutions in the HCV core region (70 and/or 91) and ISDR of NS5A of 12 patients with oral lichen planus (group 2-A) and 7 patients who did not have oral lichen planus (group 2-B) among patients (high viral loads, genotype 1b) who received interferon (IFN) therapy in group1-A.The prevalence of anti-HCV and HCV RNA was 67.80% (40/59) and 59.32% (35/59), respectively, in group 1-A and 31.76% (27/85) and 16.47% (14/85), respectively, in group 1-B. The prevalence of anti-HCV (P < 0.0001) and HCV RNA (P < 0.0001) in group 1-A was significantly higher than those in group 1-B. According to multivariate analysis, three factors - positivity for HCV RNA, low albumin level (< 4.0 g/dL), and history of smoking - were associated with the development of oral lichen planus. The adjusted odds ratios for these three factors were 6.58, 3.53 and 2.58, respectively, and each was statistically significant. No significant differences in viral factors, such as aa substitutions in the core region and ISDR of NS5A, were detected between the two groups (groups 2-A and -B).We observed a high prevalence of HCV infection in patients with oral lichen planus. Longstanding HCV infection, hypoalbuminemia, and smoking were significant risk factors for the presence of oral lichen planus in patients. It is advisable for Japanese patients with lichen planus to be tested for HCV infection during medical examination.Hepatitis C virus (HCV) infection is a major public health problem because it causes chronic hepatitis, cirrhosis and hepatocellular carcinoma (HCC). In Japan, elderly patients are at a higher risk for HCC and hep
Serum albumin and mortality risk in a hyperendemic area of HCV infection in Japan
Yumiko Nagao, Michio Sata
Virology Journal , 2010, DOI: 10.1186/1743-422x-7-375
Abstract: Of the 509 subjects, 69 had died and 55 had moved to other regions by 2002. Therefore, we analyzed 454 people for whom we could confirm life and death between 1990 and 2002. Albumin levels were assigned to two groups, low (<4.0 g/L, group A) and normal (≥4.0 g/L, group B). Of the 454 subjects analyzed, 25 were in group A and 429 in group B and the mortality was 68.0% (17/25 cases, P < 0.00001 vs. group B) and 12.1% (52/429), respectively. Mortality from hepatocellular carcinoma (HCC) was 66.7% in group A (6/9 cases, P = 0.01 vs. group B) and 15.8% (3/19) in group B. According to multivariate analysis, five factors - 50 years or older, low albumin level (<4.0 g/L), abnormal AST level, history of smoking, and absence of alcohol consumption - were associated with death. The adjusted odds ratios for these five factors were 20.65, 10.79, 2.58, 2.24 and 2.08, respectively, and each was statistically significant.We show that the serum albumin level is an independent risk factor for mortality from all causes in the residents of X town and an important prognostic indicator. Improvement of hypoalbuminaemia should be considered for improvement of prognosis.Hypoalbuminemia can be caused by various conditions, including nephrotic syndrome [1,2], heart failure [3], liver disease [4,5] and malnutrition [6]. Most cases of hypoalbuminemia among hospitalized patients are caused by acute and chronic inflammatory responses [7]. Moreover, a strong association has been reported between the serum albumin level and mortality [8]. The serum albumin level is an independent risk factor for all-cause mortality in older persons and an important prognostic indicator [9].From 1990, we have continued carrying out health screenings of the residents of X town (adult population: 7,389) in northern Kyushu, Japan, where the prevalence of hepatitis C virus (HCV) infection is the highest in the country and the mortality from liver cancer is about three times the national average [10-23]. The positive rat
Effect of oral care gel on the quality of life for oral lichen planus in patients with chronic HCV infection
Yumiko Nagao, Michio Sata
Virology Journal , 2011, DOI: 10.1186/1743-422x-8-348
Abstract: We investigated the visual analogue scale (VAS) and effects of oral care gel, REFRECARE-H?, on patients with OLP associated with HCV infection.Nine OLP patients (mean age 67.9 ± 7.6 years) with HCV-related liver diseases were recruited and their VAS score determined along with a biochemical examination of the blood. Types of OLP included erosive (6 patients) and reticular (3). REFRECARE-H?, an oral care gel (therapeutic dentifrice) containing hinokitiol, was applied by each patient as a thin layer on the oral membrane, after each meal and at bedtime for 30 days. Application of REFRECARE-H? improved the quality of life in all terms of dry mouth, breath odor, oral freshness, oral pain during rest, oral pain at a mealtimes, taste disorder, loss of appetite, sleep disorder, depressive mood and jitteriness. VAS scores of dry mouth, breath odor, oral freshness, and sleep disorder were significantly increased 30 days after application of REFRECARE-H? (P = 0.01, P = 0.05, P = 0.03, P = 0.04). VAS scores of oral pain at a mealtimes and taste disorder were increased 30 days after application of REFRECARE-H? (P = 0.06). There was an absence of side effects.REFRECARE-H? improved the quality of life for OLP. It is necessary for the hepatologist to educate patients regarding oral hygiene, as well as provide treatment of liver disease.There are 170 million chronic hepatitis C virus (HCV) carriers throughout the world, of whom an estimated two million are in Japan. HCV is the major cause of hepatocellular carcinoma (HCC) in Japan, with 70% of cases being HCV-related [1]. In addition to Japan, the number of patients with HCV-related HCC is increasing worldwide [1].HCV is associated with a broad spectrum of clinical and biological extrahepatic manifestations [2]. Chronic HCV infection has been linked to lichen planus, particularly with the involvement of the oral cavity [3]. Lichen planus is common among HCV-infected patients in Japan [4]. According to our studies, about 20% of patie
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