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Search Results: 1 - 10 of 468072 matches for " S.P. Govindwar "
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In vivo and In vitro Effect of Sulfamerazine on Hepatic Mixed Function Oxidase in Rats
P.B. Dandge,S.P. Govindwar
Research Journal of Pharmacology , 2013, DOI: 10.3923/rjpharm.2011.53.58
Abstract: Sulfamerazine (SMR) administration (i.p., 3 days) of different doses to adult male rats showed significant decrease in electron transport components and drug metabolizing enzymes. In longer duration study, 100 mg SMR kg-1 caused significant decreases in cytochrome P-450 and activities of aminopyrine N-demethylase and aniline hydroxylase. In inhibitory dose of 100 mg SMR kg-1 was selected for dosing young male, old male and adult female rats. Sulfamerazine administration to young, old male and female rats resulted in a significant decrease in electron transport component and drug metabolizing activities at 100 mg SMR kg-1 dose level. All other parameters were unchanged. Sulfamerazine resulted in uncompetitive type of inhibition (Ki = 3.0 mM) of aminopyrine N-demethylase in vitro. Sulfamerazine destructed the spectral and catalytic activity of cytochrome P-450. The studies suggest that SMR is a substrate of the mixed function oxidase system and inhibition is dependent on dosage, age and sex of the animals.
Complex treatment of patients with malignant cerebral gliomas of supratentorial localization: follow -up results
S.P. Bazhanov
Saratov Journal of Medical Scientific Research , 2010,
Abstract: The aim of the research is to investigate specific antitumor immunotherapy on the basis of autologous dendritic cells in the complex treatment of patients with malignant cerebral gliomas of supratentorial localization. 55 patients with malignant gliomas (41 with glioblastomas, 14 with anaplastic astrocytomas) have been analysed who had received complex treatment with specific immunotherapy. All the patients were hospitalized at complicated disease stages and with tumors over 5 cm in diameter. Specific antitumor immunotherapy was conducted according to the original methodology and included autologous dendritic cells with tumor antigens and tumor cells lysate. Treatment course consisted of autologous dendritic cells introduction on the 10-12th day after the operation. It was performed every 2-3 months. Follow-up results of specific antitumor immunotherapy with autologous dendritic cells were analised. It was noted that lifetime of patients with malignant supratentorial gliomas became longer in comparison with average statistical results. In conclusion it is of importance to point out that specific antitumor immunotherapy included into complex treatment of malignant gliomas allowing to increase disease remission and quality of life
The need to understand the emotions of anger, fear and guilt when counselling religious cult victims
S.P. Pretorius
Koers : Bulletin for Christian Scholarship , 2008, DOI: 10.4102/koers.v73i2.162
Abstract: Victims of religious cults are systematically influenced by the beliefs, teachings and practices of the group to adopt the identity and personality befitting the religious cult. This cult identity and personality that is believed to be God-pleasing views the outside world as evil and a threat to the spiritual well-being of cult members. In order to maintain cult members in a state which is supposedly pure and free from contamination by the evil world, they are taught to cultivate an antagonistic and resistant attitude towards any doctrine or person contradicting the cult’s views. Any attempt by an “outsider” to communicate with cult members is prohibited. Any attempt to counsel cult members must be preceded by the establishment of a trust relationship that will overcome the resistance and open up communication. The counselling process that follows should address the emotional conditions of anger, false guilt and fear in order to restore the person’s self-worth and ability to adapt to the outside world. This article contends that addressing false guilt, anger and fear is an important and necessary phase in the process of helping cult members to recover and reintroducing them to the world.
Mind control: The secret weapon utilised by religious cults to control their followers
S.P. Pretorius
Koers : Bulletin for Christian Scholarship , 2004, DOI: 10.4102/koers.v69i4.319
Abstract: The aim of this article is to create awareness of the dangers of religious cults. The process utilised by these cults to recruit members and to control their lives is so subtle that members are led to believe that they joined out of their own free will. A brief discussion of what religious cults are as well as how they function is followed by an explanation of mind control and how it is utilised by cults. This article maintains that mind control is the secret weapon with which leaders of cults lure their followers under false pretences to mislead, control and make them dependent on the cult.
Ontwikkeling en perspektief in die Suid-Afrikaanse industrie
S.P. Ligthelm
Koers : Bulletin for Christian Scholarship , 1967, DOI: 10.4102/koers.v34i4&5.1426
Abstract: Die eerste nywerheidsontwikkeling in Suid-Afrika was onvermydelik gekoppel aan die landbou-, die wyn- en verwante nywerhede in die Kaap en die suikernywerheid in Natal. In beide gevalle het dié nywerhede ’n belangrike bydrae gemaak in die globale ontwikkeling in ons land, en in die toekoms sal dit steeds 'n belangrike bydrae lewer.
Gospel and constitutional imperatives: the right to life
S.P. Giles
In die Skriflig , 2011, DOI: 10.4102/ids.v45i1.5
Abstract: Gospel and constitutional imperatives: the right to life In the Republic of South Africa, Christians are called to live out gospel imperatives within the legal framework of the Constitution. Ethical issues about the right to life are considered from the perspectives of selected gospel and constitutional imperatives. Gospel imperatives impose themselves as a consequence of Christian discipleship. These are many and diverse, both explicit and implicit. Christian vocation, discipleship, witness and perseverance, are foundational and integral to the praxis of Christian daily living. These facets of Christian life are illustrated by the selected gospel imperatives, “Follow me” (Matt. 4:19 and synoptic parallels), “Love God, and your neighbour as yourself” (Matt. 22:34-40 and synoptic parallels), and “Take up your cross” (Matt. 10:38 and synoptic parallels). The central theoretical argument of this article is driven from a reformed ethical perspective. Gospel imperatives have priority over constitutional imperatives since gospel imperatives are of divine origin and constitutional imperatives of human origin. Acknowledgement of these priorities informs the Christian ethical perspective on the right to life and on abortion.
Cyborgs In Scientific Literature
S.P. Rajguru
Indian Streams Research Journal , 2012,
Abstract: Cyborgs were introduced into feminist discourse in Donna Haraway's“Manifesto for Cyborgs”, published in the Socialist Review1985. In this “Manifesto”,Haraway brought together the contextual arguments of the postmodern philosopherswith awidespread, deepening disillusionment with the mainstream political feminism ofthe1960s and 70s. Haraway argued for the Cyborg's usefulness as “a fiction mappingour social and bodily reality and as an imaginative resource suggesting some veryfruitful couplings.” Every human is a natural-born cyborg and always in the process oftransformation
The evolving role of liver biopsy: what are the gold standards today?
S.P. Dourakis
Annals of Gastroenterology , 2007,
Treatment of relapser /nonresponder patients
S.P. Dourakis
Annals of Gastroenterology , 2007,
Hepatitis C and steatohepatitis: Is there any relationship?
S.P. Dourakis
Annals of Gastroenterology , 2007,
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