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Search Results: 1 - 10 of 325216 matches for " S. Sreenivasa "
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[1-(4-Nitrobenzyl)-2-butyl-4-chloro-1H-imidazol-5-yl]-4, 5-dihydro-1-phenyl-1H-pyrazole: Synthesis, Anti-Inflammatory and Analgesic Activities  [PDF]
S. Sreenivasa, B. J. Shankar
Open Journal of Medicinal Chemistry (OJMC) , 2013, DOI: 10.4236/ojmc.2013.32007

In the present investigation, series of Bis (heterocycle)s bearing pyrazoline in combination of the imidazole derivatives have been synthesized via 1,3-dipolar cycloaddition reactions of N-(nitrobenzyl)-imidazole nitrile imines with different dipolarophiles. All the newly synthesized compounds were characterized and screened for analgesic-anti-inflammatory activities and were compared with the standard drugs. The compounds exhibited excellent anti-inflammatory and analgesic activities. Out of the compounds studied 4b, 4d and 4g compounds shown statistically significant activity comparable to the standard drugs Ibuprofen and Aspirin at the same dose.

Cytogenetic abnormalities in 200 male infertile cases in the southern region of India  [PDF]
G. Sreenivasa, Suttur S. Malini, Prasanna Kumari, Usha R. Dutta
Open Journal of Genetics (OJGen) , 2013, DOI: 10.4236/ojgen.2013.32A3005
Abstract: Chromosomal abnormalities are one of the major causes of male infertility. But the exact mechanism by which chromosomal anomalies induces infertility is still not clear. Many studies have documented the chromosomal abnormalities ranging from 2.2% to 15.7% in infertile men. The present study has been carried out to document and find out the genetic cause of male infertility in the Southern region of India. The cytogenetic analysis of 200 male infertile cases, referred due to primary infertility from 2009 to 2012, were analyzed by GTG banding and evaluated retrospectively. The semen analysis was also performed. A total of 15 cases (7.5%) showed chromosomal aberrations. Four (2%) were 47, XXY and mosaic 47,XXY; Two (1%) were structural autosomal abnormalities; Two (1%) were inversion Y; Seven (3.5%) cases were Y heterochromatin variants and 185 cases (92.5%) showed normal 46,XY karyotype. The chromosomal abnormalities in our study is also in agreement with the data from the literature. Also abnormal spermatogenesis is observed in these cases. Apart from chromosomal analysis further in depth molecular analysis and genetic counseling is suggestive in such cases, especially those interested in IVF technologies.
Distributed Data Mining and Mining Multi-Agent Data
Vuda Sreenivasa Rao,Dr. S Vidyavathi
International Journal on Computer Science and Engineering , 2010,
Abstract: The problem of distributed data mining is very important in network problems. Ina distributed environment (such as a sensor or IP network), one has distributed probes placed at strategic locations within the network. The problem here is to be able to correlatethe data seen at the various probes, and discover patterns in the global data seen at all the different probes. There could be different models of distributed data mining here, but one could involve a NOC that collects data from the distributed sites, and another in which all sites are treated equally. The goal here obviously would be to minimize the amount of data shipped between the various sites — essentially, to reduce the communication overhead. In distributed mining, one problem is how to mine across multipleheterogeneous data sources: multi-database and multirelational mining. Another important new area is adversary data mining. In a growing number of domains — email spam, counter-terrorism, intrusiondetection/computer security, click spam, search engine spam, surveillance, fraud detection, shop bots, file sharing, etc. — data mining systems face adversaries that deliberately manipulate the data to sabotage them (e.g. make them produce false negatives). In this paper need to develop systems that explicitly take this into account, by combining data mining with game theory.
Vuda Sreenivasa Rao,Dr. S Vidyavathi
Indian Journal of Computer Science and Engineering , 2010,
Abstract: Data mining technology has emerged as a means for identifying patterns and trends from large quantities of data. Data mining is a computational intelligence discipline that contributes tools for data analysis, discovery of new knowledge, and autonomous decision making. Clustering is a primary data description method in data mining which group’s most similar data. The data clustering is an important problem in a wide variety of fields. Including data mining, pattern recognition, and bioinformatics. It aims to organize a collection of data items into clusters, such that items within a cluster are more similar to each other than they are items in the other clusters. There are various algorithms used to solve this problem In this paper, we use FCM (Fuzzy C -mean) clustering algorithm and MFPCM (Modified Fuzzy Possibilistic C - mean) clustering algorithm. In thispaper we compare the performance analysis of Fuzzy C mean (FCM) clustering algorithm and compare it with Modified Fuzzy possibilistic C mean algorithm. In this we compared FCM and MFPCM algorithm on different data sets. We measure complexity of FCM and MFPCM atdifferent data sets. FCM clustering is a clustering technique which is separated from Modified Fuzzy Possibililstic C mean that employsPossibililstic partitioning.
Real Time Prosody Modification  [PDF]
Krothapalli Sreenivasa Rao
Journal of Signal and Information Processing (JSIP) , 2010, DOI: 10.4236/jsip.2010.11006
Abstract: Real time prosody modification involves changing the prosody parameters such as pitch, duration and intensity of speech in real time without affecting the intelligibility and naturalness. In this paper prosody modification is performed using instants of significant excitation (ISE) of the vocal tract system during production of speech. In the conventional prosody modification system the ISE are computed using group delay function, and it is computationally intensive task. In this paper, we propose computationally efficient methods to determine the ISE suitable for prosody modification in interactive (real time) applications. The overall computational time for the prosody modification by using the proposed method is compared with the conventional prosody modification method which uses the group delay function for computing the ISE.
4′-Cyanobiphenyl-4-yl 7-diethylamino-2-oxo-2H-chromene-3-carboxylate
S. Sreenivasa,H. T. Srinivasa,B. S. Palakshamurthy,Vijith Kumar
Acta Crystallographica Section E , 2013, DOI: 10.1107/s1600536813001591
Abstract: In the title compound, C27H22N2O4, the dihedral angles between the central benzene ring and the cyanobenzene ring and the 2H-coumarin ring system (r.m.s. deviation = 0.014 ) are 22.95 (11) and 75.59 (8)°, respectively. Both terminal C atoms of the pendant diethylamino group lie to the same side of the coumarin ring system [deviations = 1.366 (2) and 1.266 (2) ]. In the crystal, molecules are linked by C—H...O and C—H...N hydrogen bonds and a C—H...π interaction, generating a three-dimensional network.
Methyl 4-benzyloxy-2-hydroxybenzoate
B. S. Palakshamurthy,H. T. Srinivasa,Vijith Kumar,S. Sreenivasa
Acta Crystallographica Section E , 2012, DOI: 10.1107/s1600536812046491
Abstract: In the title compound, C15H14O4, the dihedral angle between the benzene rings is 67.18 (8)°. The Ca—Cm—O—Ca (a = aromatic and m = methylene) torsion angle is 172.6 (3)° and an intramolecular O—H...O hydrogen bond generates an S(6) ring. In the crystal, molecules are linked by C—H...O hydrogen bonds into zigzag chains propagating in [001] and C—H...π interactions also occur.
S. Sreenivasa,H. C. Anitha,K. E. ManojKumar,J. Tonannavar
Acta Crystallographica Section E , 2013, DOI: 10.1107/s1600536813000317
Abstract: In the crystal structure of the title compound, C19H21F3N2O2S, the piperazine ring adopts a chair conformation. The dihedral angles between the mean plane of the piperazine ring and the tosyl and trifluoromethylphenyl rings are 74.52 (3) and 68.30 (2)°, respectively. The sulfonamide N atom deviates from the plane defined by the three attached atoms by 0.327 (1) . The crystal structure is stabilized by weak C—H...π interactions.
4-Nitrophenyl 4-hydroxy-3-methylbenzoate
S. Sreenivasa,H. C. Devarajegowda,H. T. Srinivasa,Vijith Kumar
Acta Crystallographica Section E , 2012, DOI: 10.1107/s1600536812048271
Abstract: The asymmetric unit of the title compound, C14H11NO5, contains two independent molecules in which the dihedral angles between the benzene rings are 89.27 (16) and 77.14 (12)°. In the crystal, molecules are linked by O—H...O hydrogen bonds, generating C(8) chains propagating in [010] for one molecule and [001] C(8) chains for the other. The chains are connected by C—H...O hydrogen bonds and π–π interactions [shortest centroid–centroid distance = 3.5908 (12)°], generating a three-dimensional network.
S. Sreenivasa,K. E. ManojKumar,T. Srinivasan,P. A. Suchetan
Acta Crystallographica Section E , 2013, DOI: 10.1107/s1600536812050982
Abstract: The title compound, C10H16N4, crystalizes with two molecules (A and B) in the asymmetric unit in which the dihedral angles between the piperidine and pyrimidine rings are 47.5 (1) and 10.3 (1)°. The four C atoms of the pyrimidine ring in one of the molecules are disordered over two sets of sites with occupancy factors 0.508 (11):0.492 (11). In the crystal, the A molecules are linked to one another through N—H...N hydrogen bonds, generating R22(8) ring patterns and forming inversion dimers. These dimers are further connected on either side to a B molecule through pairs of N—H...N hydrogen bonds, resulting in a tetrameric unit.
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