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Search Results: 1 - 10 of 327641 matches for " S. Raymond "
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μ-Conotoxins as Leads in the Development of New Analgesics
Raymond S. Norton
Molecules , 2010, DOI: 10.3390/molecules15042825
Abstract: Voltage-gated sodium channels (VGSCs) contain a specific binding site for a family of cone shell toxins known as μ-conotoxins. As some VGSCs are involved in pain perception and μ-conotoxins are able to block these channels, μ-conotoxins show considerable potential as analgesics. Recent studies have advanced our understanding of the three-dimensional structures and structure-function relationships of the μ-conotoxins, including their interaction with VGSCs. Truncated peptide analogues of the native toxins have been created in which secondary structure elements are stabilized by non-native linkers such as lactam bridges. Ultimately, it would be desirable to capture the favourable analgesic properties of the native toxins, in particular their potency and channel sub-type selectivity, in non-peptide mimetics. Such mimetics would constitute lead compounds in the development of new therapeutics for the treatment of pain.
International Workshop on the Future of Physics and Society, Debrecen, Hungary, 4-6 March 1999, Workshop Summary
Raymond S. Mackintosh
Physics , 1999,
Abstract: The Debrecen workshop was one of a number held in preparation for the UNESCO-ICSU World Conference on Science, which will be held in Budapest, June 1999. A report representing the views of the workshop, prepared for that conference and containing a number of recommended actions, is included with this summary. The workshop affirmed the ongoing importance of physics for its own sake and as part of our culture, as a key element in our increasingly unified science and as an essential contributor to the solution of environmental and energy problems. The problems faced by physics as an activity and as an educational subject were discussed and actions for both society as a whole and the physics community itself were put forward.
The Gauss Map and 2+1 Gravity
Raymond S. Puzio
Physics , 1994, DOI: 10.1088/0264-9381/11/11/009
Abstract: We prove that the Gauss map of a surface of constant mean curvature embedded in Minkowski space is harmonic. This fact will then be used to study 2+1 gravity for surfaces of genus higher than one. By considering the energy of the Gauss map, a canonical transform between the ADM reduced variables and holonomy variables can be constructed. This allows one to solve (in principle) for the evolution in the ADM variables without having to explicitly solve the constraints first.
Inverse scattering: applications to nuclear physics
Raymond S. Mackintosh
Physics , 2012,
Abstract: In what follows we first set the context for inverse scattering in nuclear physics with a brief account of inverse problems in general. We then turn to inverse scattering which involves the S-matrix, which connects the interaction potential between two scattering particles with the measured scattering cross section. The term `inverse' is a reference to the fact that instead of determining the scattering S-matrix from the interaction potential between the scattering particles, we do the inverse. That is to say, we calculate the interaction potential from the S-matrix. This review explains how this can now be done reliably, but the emphasis will be upon reasons why one should wish to do this, with an account of some of the ways this can lead to understanding concerning nuclear interactions.
Spin dynamics of the ferromagnetic superconductor UGe$_{2}$
S. Raymond,A. Huxley
Physics , 2003, DOI: 10.1016/j.physb.2004.04.052
Abstract: Inelastic neutron scattering was used to study the low energy magnetic excitations of the ferromagnetic superconductor UGe$_{2}$. The ferromagnetic fluctuations are of Ising nature with a non-conserved magnetization and have an intermediate behavior between localized and itinerant magnetism.
Ising incommensurate spin resonance of CeCoIn$_{5}$: a dynamical precursor of the Q-phase
S. Raymond,G. Lapertot
Physics , 2015,
Abstract: It is shown by detailed inelastic neutron scattering experiments that the gapped collective magnetic excitation of the unconventional superconductor CeCoIn$_{5}$, the spin resonance mode, is incommensurate and that the corresponding fluctuations are of Ising nature. The incommensurate peak position of these fluctuations corresponds to the propagation vector of the adjacent field induced static magnetic ordered phase, the so-called Q-phase. Furthermore, the direction of the magnetic moment fluctuations is also the direction of the ordered magnetic moments of the Q-phase. Hence the resonance mode and the Q-phase share the same symmetry and this strongly supports a scenario where the static order is realized by a condensation of the magnetic excitation.
Phonon spectrum of the ferromagnetic superconductor UGe$_2$ : Consequences for the specific heat
S. Raymond,A. Huxley
Physics , 2005, DOI: 10.1103/PhysRevB.73.094420
Abstract: We report inelastic neutron scattering measurements of the phonon spectrum of the pressure-induced ferromagnetic superconductor UGe$_{2}$. No changes of the spectrum were found on cooling down to low temperature. The phonon contribution to the specific heat was estimated from a fit to our data. The excess specific heat previously noted at around $T_{x} \approx$ 30 K is not due to phonons but is well described by the temperature dependence of the magnetic order parameter at the molecular field level.
Artificial scaling laws of the dynamical magnetic susceptibility in heavy-fermion systems
W. Knafo,S. Raymond
Physics , 2005, DOI: 10.1016/j.physleta.2005.04.041
Abstract: We report here how artificial, thus erroneous, scaling laws of the dynamical magnetic susceptibility can be obtained when data are not treated carefully. We consider the example of the heavy-fermion system Ce$_{0.925}$La$_{0.075}$Ru$_{2}$Si$_{2}$ and we explain how different kinds of artificial scaling laws in $E/T^\beta$ can be plotted in a low temperature regime where the dynamical susceptibility is nearly temperature independent.
Evidence for L-dependence generated by channel coupling: O16 scattering from C12 at 115.9 Mev
Raymond S. Mackintosh
Physics , 2015,
Abstract: The inclusion of strong coupling to states of projectile and target nuclei for 115.9 MeV \nuc{16}{O} scattering from \nuc{12}{C} leads to an S-matrix which, when subject to $S_{L} \rightarrow V(r) $ inversion, yields highly undulatory local potentials. Previous work has shown that explicitly $L$-dependent non-undulatory potentials are equivalent to undulatory $L$-independent potentials with the same S-matrix. Here we show that $L$-independent equivalents for certain simple model $L$-dependent potentials exhibit undulatory features qualitatively similar to those arising from channel coupling for 115.9 MeV \nuc{16}{O} scattering from \nuc{12}{C}. We discuss the relevance to the question of $L$-dependence as a generic property of nucleus-nucleus interactions.
Work Personality and Decision Making Styles among Working and Non-Working Students  [PDF]
Raymond Doe, Matthew S. Castillo, Andrené B. McKinney
Open Journal of Social Sciences (JSS) , 2017, DOI: 10.4236/jss.2017.56024
Abstract:
This study investigated adaptive decision making styles (DMSs; Rational and Intuitive) among working and non-working students. These cognitive styles involve approaching tasks objectively, analytically, thoroughly and unemotionally. Workers performing tasks in organizations are expected to use intuition and make rational business decisions compared to non-workers. Work personality, which is influenced by both home and school environments, has been identified to influence critical adult work behaviors such as task completion as well as how we engage with others in work settings. Increasingly, college aged students are working full or part-time and have to combine their studies with work demands in addition to other responsibilities at home. Prior studies have found no significant differences between working and non-working students on outcomes such as academics and social experiences. However, working students seem to transfer and optimize their decision making competencies to be successful on the job and in college compared to non-working students. We predicted that task oriented working students would use more adaptive decision making styles than non-workers after controlling for gender and age. A total of 130 respondents participated in this study and the results partially supported our assertion. Task oriented working students were significantly different than non-working students in the use of the rational decision making style than any other DMS. Our results were consistent with previous studies on adaptive decision making styles.
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