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Search Results: 1 - 10 of 2586 matches for " Ryusuke Yoshida "
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Mucinous Carcinoma of the Breast Accompanied by Coarse Calcification  [PDF]
Hitomi Tani, Ryusuke Murakami, Tamiko Yoshida, Keiko Yanagihara, Shinya Iida, Shinichi Tsuchiya
Open Journal of Medical Imaging (OJMI) , 2012, DOI: 10.4236/ojmi.2012.24023
Abstract: Mucinous carcinoma of the breast has histologically distinct features and constitutes 1-3% of all breast cancers. It produces variable amounts of extracellular epithelial mucin and clinically its prognosis is far better than for other types of invasive carcinoma. On the other hand, coarse calcification is a common mammographic feature of benign tumors. There have been few reported cases of breast cancer containing coarse calcification. We present a unique 40 year-old female case of mucinous carcinoma of the breast accompanied by coarse calcification on mammography, which was mimicking fibroadenoma and an unusual variant of breast cancer. This case illustrates the importance of bearing in mind that mucinous carcinoma may demonstrate coarse calcification.
Genetic and Molecular Basis of Individual Differences in Human Umami Taste Perception
Noriatsu Shigemura, Shinya Shirosaki, Keisuke Sanematsu, Ryusuke Yoshida, Yuzo Ninomiya
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0006717
Abstract: Umami taste (corresponds to savory in English) is elicited by L-glutamate, typically as its Na salt (monosodium glutamate: MSG), and is one of five basic taste qualities that plays a key role in intake of amino acids. A particular property of umami is the synergistic potentiation of glutamate by purine nucleotide monophosphates (IMP, GMP). A heterodimer of a G protein coupled receptor, TAS1R1 and TAS1R3, is proposed to function as its receptor. However, little is known about genetic variation of TAS1R1 and TAS1R3 and its potential links with individual differences in umami sensitivity. Here we investigated the association between recognition thresholds for umami substances and genetic variations in human TAS1R1 and TAS1R3, and the functions of TAS1R1/TAS1R3 variants using a heterologous expression system. Our study demonstrated that the TAS1R1-372T creates a more sensitive umami receptor than -372A, while TAS1R3-757C creates a less sensitive one than -757R for MSG and MSG plus IMP, and showed a strong correlation between the recognition thresholds and in vitro dose - response relationships. These results in human studies support the propositions that a TAS1R1/TAS1R3 heterodimer acts as an umami receptor, and that genetic variation in this heterodimer directly affects umami taste sensitivity.
Sour Taste Responses in Mice Lacking PKD Channels
Nao Horio,Ryusuke Yoshida,Keiko Yasumatsu,Yuchio Yanagawa,Yoshiro Ishimaru,Hiroaki Matsunami,Yuzo Ninomiya
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0020007
Abstract: The polycystic kidney disease-like ion channel PKD2L1 and its associated partner PKD1L3 are potential candidates for sour taste receptors. PKD2L1 is expressed in type III taste cells that respond to sour stimuli and genetic elimination of cells expressing PKD2L1 substantially reduces chorda tympani nerve responses to sour taste stimuli. However, the contribution of PKD2L1 and PKD1L3 to sour taste responses remains unclear.
Hydrodynamics and Nonlocal Conductivities in Vortex States
Ryusuke Ikeda
Physics , 1995,
Abstract: A hydrodynamical description for vortex states in type II superconductors with no pinning is presented based on the time-dependent GL equation, and the nonlocal conductivities are examined in terms of Kubo formula. Typically, the nonlocal conductivities deviate from the usual vortex flow expressions as the nonlocality parallel to the field becomes weaker than that perpendicular to the field associated with the freezing to the vortex lattice, and, for instance, the dc Hall conductivity nonlocal only in directions perpendicular to the field becomes zero in the vortex lattice due to its infinite shear viscosity. Various situations are discussed on the basis of the resulting expressions.
Impurity-induced broadening of the transition to a Fulde-Ferrell-Larkin-Ovchinnikov phase
Ryusuke Ikeda
Physics , 2009, DOI: 10.1103/PhysRevB.81.060510
Abstract: Recent study on doping effects in the heavy fermion superconductor CeCoIn$_5$ has shown that a small amount of doping induces unexpectedly large broadening of the second order transition into the high field and low temperature (HFLT) phase of this material. Motivated by this observation, effects of quenched disorder on the second order transition into a longitudinal Fulde-Ferrell-Larkin-Ovchinnikov (FFLO) state are examined. The observed large broadening of the transition is naturally explained as a consequence of softness of each FFLO nodal plane. The present results strongly support the scenario identifying the HFLT phase of CeCoIn$_5$ with a longitudinal FFLO vortex state.
Comment on "Spatial line nodes and fractional vortex pairs in the Fulde-Ferrell-Larkin-Ovchinnikov phase"
Ryusuke Ikeda
Physics , 2007, DOI: 10.1103/PhysRevLett.102.069703
Abstract: This is a Comment on Phys.Rev.Lett. 100, 017001 (2008).
Quantum Resistive Transition in Type II Superconductors under Magnetic Field
Ryusuke Ikeda
Physics , 1995, DOI: 10.1143/JPSJ.65.33
Abstract: It is shown that, within a Ginzburg-Landau (GL) formalism, the superconducting fluctuation is insulating at zero temperature even if the fluctuation dynamics is metallic (dissipative). Based on this fact, the low temperature behavior of the $H_{c2}$-line and the resistivity curves near a zero temperature transition are discussed. In particular, it is pointed out that the neglect of quantum fluctuations in data analysis of the dc resistivity may lead to an under-estimation of the $H_{c2}$ values near zero temperature.
Superconducting transition in disordered granular superconductors in magnetic fields
Ryusuke Ikeda
Physics , 2005, DOI: 10.1103/PhysRevB.74.054510
Abstract: Motivated by a recent argument that the superconducting (SC) transition field of three-dimensional (3D) disordered superconductors with granular structure in a nonzero magnetic field should lie above $H_{c2}(0)$ in low $T$ limit, the glass transition (or, in 2D, crossover) curve $H_g(T)$ of disordered quantum Josephson junction arrays is examined by incorporating SC fluctuations. It is found that the glass transition or crossover in the granular materials can be described on the same footing as the vortex-glass (VG) transition in amorphous-like (i.e., nongranular) materials. In most of 3D granular systems, the vanishing of resistivity upon cooling should occur even above $H_{c2}(0)$, while the corresponding sharp drop of the resistivity in 2D case may appear only below $H_{c2}$ as a result of an enhanced quantum fluctuation.
Hydrodynamics and Nonlocal Conductivities in Vortex States of Type II Superconductors
Ryusuke Ikeda
Physics , 1995, DOI: 10.1143/JPSJ.64.3925
Abstract: A hydrodynamical description for vortex states in type II superconductors is presented based on the time-dependent Ginzburg-Landau equation (TDGL). In contrast to the familiar extension of a single vortex dynamics based on the force balance, our description is consistent with the known hydrodynamics of a rotating neutral superfluid and correctly includes informations on the Goldstone mode. Further it enables one to examine nonlocal conductivities perpendicular to the magnetic field in terms of Kubo formula. The nonlocal conductivities deviate from the usual vortex flow expressions typically when the nonlocality parallel to the field becomes weaker than the perpendicular one measuring a degree of positional correlations, and, for instance, the superconducting contribution of dc Hall conductivity nonlocal only in directions perpendicular to the field becomes vanishingly small in the situations with large shear viscosity, leading to an experimentally measurable relation $\rho_{xy} \sim {\rho_{xx}^2}$ among the total resistivity components. Other situations are also discussed on the basis of the resulting expressions.
Heat Kernel for Spin-3/2 Rarita-Schwinger Field in General Covariant Gauge
Ryusuke Endo
Physics , 1994, DOI: 10.1088/0264-9381/12/5/007
Abstract: The heat kernel for the spin-3/2 Rarita-Schwinger gauge field on an arbitrary Ricci flat space-time ($d>2$) is investigated in a family of covariant gauges with one gauge parameter $\alpha$. The $\alpha$-dependent term of the kernel is expressed by the spin-1/2 heat kernel. It is shown that the axial anomaly and the one-loop divegence of the action are $\alpha$-independent, and that the conformal anomaly has an $\alpha$-dependent total derivative term in $d=2m\geq6$ dimensions.
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