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Search Results: 1 - 10 of 461713 matches for " Rupani A "
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Osteoblasts and their applications in bone tissue engineering
Rupani A, Balint R, Cartmell SH
Cell Health and Cytoskeleton , 2012, DOI: http://dx.doi.org/10.2147/CHC.S21845
Abstract: teoblasts and their applications in bone tissue engineering Review (2262) Total Article Views Authors: Rupani A, Balint R, Cartmell SH Published Date May 2012 Volume 2012:4 Pages 49 - 61 DOI: http://dx.doi.org/10.2147/CHC.S21845 Received: 05 March 2012 Accepted: 22 March 2012 Published: 08 May 2012 Asha Rupani1, Richard Balint2, Sarah H Cartmell1,2 1Institute of Science and Technology in Medicine, Keele University, Hartshill, Stoke-on-Trent, UK; 2Materials Science Centre, The University of Manchester, Manchester, UK Abstract: Tissue engineering is an emerging therapy that offers a new solution to patients suffering from bone loss. It utilizes cells derived from such sources as a patient's own bone or bone marrow, which are laboratory-isolated, grown (so they multiply in number), and placed onto a degradable material, or scaffold, that has mechanical/chemical properties appropriate to the bone section that it is replacing. The cells plus the scaffold are then grown in a container, or bioreactor, which is necessary as it provides the correct environment required for the cells to proliferate, differentiate, and to produce extracellular matrix. The following review focuses on the use of osteoblasts for bone tissue engineering.
Maternal mortality: An autopsy audit
Jashnani K,Rupani A,Wani R
Journal of Postgraduate Medicine , 2009,
Abstract: Background: The process of audit standardizes protocols in departments and has long-term benefits. Maternal autopsies though routinely performed, deserve a special attention. Aims: This study was carried out to calculate the maternal mortality ratio (MMR) in a tertiary care hospital and to correlate final cause of death with the clinical diagnosis. An audit of maternal autopsies was carried out to evaluate current practices, identify fallacies and suggest corrective measures to rectify them. Materials and Methods: Eighty-nine autopsies of maternal deaths in the period 2003 to 2007 were studied in detail along with the clinical details. Results: There were 158 maternal deaths and 13940 live births in this five-year period. Maternal mortality rate was found to be very high (1133/ 100000 live births) in our institution with a high number of complicated referral cases (68/89 cases, 76%). Of the 89 autopsies, acute fulminant viral hepatitis was the commonest cause of indirect maternal deaths (37 cases, 41.5%). This was followed by direct causes like pregnancy-induced hypertension (12 cases, 13.4%) and puerperal sepsis (10 cases, 11.2%). Certain fallacies were noted during the audit process. Conclusion: During the audit it was realized that in maternal mortality autopsies, special emphasis should be given to clinicopathologic correlation, microbiological studies, identification of thromboembolic phenomenon and adequate sectioning of relevant organs. We found difficulty in identification of placental bed in the uterus in postpartum autopsies. A systematic approach can help us for better understanding of the pathophysiology of diseases occurring in pregnancy.
Images in pathology: verrucous haemangioma.
Rupani A,Madiwale C,Vaideeswar P
Journal of Postgraduate Medicine , 2000,
Abstract:
Osteoblasts and their applications in bone tissue engineering
Rupani A,Balint R,Cartmell SH
Cell Health and Cytoskeleton , 2012,
Abstract: Asha Rupani1, Richard Balint2, Sarah H Cartmell1,21Institute of Science and Technology in Medicine, Keele University, Hartshill, Stoke-on-Trent, UK; 2Materials Science Centre, The University of Manchester, Manchester, UKAbstract: Tissue engineering is an emerging therapy that offers a new solution to patients suffering from bone loss. It utilizes cells derived from such sources as a patient's own bone or bone marrow, which are laboratory-isolated, grown (so they multiply in number), and placed onto a degradable material, or scaffold, that has mechanical/chemical properties appropriate to the bone section that it is replacing. The cells plus the scaffold are then grown in a container, or bioreactor, which is necessary as it provides the correct environment required for the cells to proliferate, differentiate, and to produce extracellular matrix. The following review focuses on the use of osteoblasts for bone tissue engineering.Keywords: osteoblast, bone, tissue engineering, regenerative medicine, orthopaedic
Primary anaplastic large cell lymphoma of central nervous system-A case report
Rupani A,Modi C,Desai S,Rege J
Journal of Postgraduate Medicine , 2005,
Abstract: Central nervous system (CNS) involvement is extremely rare in anaplastic large cell lymphoma (ALCL). Primary ALCL of CNS on radiology is often misdiagnosed as tuberculosis. We report a fatal case of primary ALCL of CNS in a 17 year old male. He came with history of headache and left partial seizures. MRI showed a well- circumscribed lesion in the right fronto-parietal lobe eroding the skull bone. Biopsy showed large pleomorphic cells. Immunohistochemical stains showed positivity for CD30, CD43, EMA and ALK-1. In spite of radiotherapy and steroids, patient expired. Hence a high level of suspicion is essential for early diagnosis and for instituting appropriate treatment.
Ligament Tissue Engineering and Its Potential Role in Anterior Cruciate Ligament Reconstruction
E. W. Yates,A. Rupani,G. T. Foley,W. S. Khan,S. Cartmell,S. J. Anand
Stem Cells International , 2012, DOI: 10.1155/2012/438125
Abstract: Tissue engineering is an emerging discipline that combines the principle of science and engineering. It offers an unlimited source of natural tissue substitutes and by using appropriate cells, biomimetic scaffolds, and advanced bioreactors, it is possible that tissue engineering could be implemented in the repair and regeneration of tissue such as bone, cartilage, tendon, and ligament. Whilst repair and regeneration of ligament tissue has been demonstrated in animal studies, further research is needed to improve the biomechanical properties of the engineered ligament if it is to play an important part in the future of human ligament reconstruction surgery. We evaluate the current literature on ligament tissue engineering and its role in anterior cruciate ligament reconstruction.
Eosinophillic myocarditis and coronary arteritis in a fatal case of asthma
Rupani Asha,Amonkar Gayathri,Deshpande Jaya
Indian Journal of Pathology and Microbiology , 2010,
Abstract: Mortality is very unusual in the case of asthma. We recently came across a fatal case of asthma which showed a rare combination of unusual complications like eosinophilic myocarditis, coronary arteritis, biventricular cardiac hypertrophy, eosinophilic pneumonitis and pulmonary hypertension.
Unusual cutaneous ulcers in a case of miliary tuberculosis
Amladi Sangeeta,Jerajani Hemangi,Rupani Sadhana
Indian Journal of Dermatology, Venereology and Leprology , 1993,
Abstract: A 3-year old girl had multiple, large, deep, infected ulcers on the extremities and buttocks for 1 years. Additional features included malnutrition, Cushingoid facies with buffalo hump, and absence of any underlying bony involvement. Edge biopsy showed a tuberculous picture without vasculitis or acid-fast bacilli; X-ray of the chest revealed military tuberculosis. The ulcers, although atypical, healed completely and rapidly on anti-tuberculous therapy.
Pulmonary actinomycosis masquerading as tuberculosis
Rupani Asha,Amonkar Gayathri,Deshpande Jaya
Indian Journal of Pathology and Microbiology , 2009,
Abstract:
Micropapillary carcinoma of urinary bladder
Shah Vinaya,Rupani Asha,Pathak Hemant
Indian Journal of Pathology and Microbiology , 2008,
Abstract:
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