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Search Results: 1 - 10 of 198626 matches for " Rubén Castellano Durán "
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Agresión y violencia en América Latina. Perspectivas para su estudio: Los otros son la amenaza
Rubén Castellano Durán,Rubén Darío Castellano González
Espacio Abierto , 2012,
Abstract: En este artículo se pretende evidenciar los condicionantes teóricos y extrateóricos que subyacen en el estudio de la violencia, destacando el homicidio como su máxima expresión en América Latina, presentes tanto en las Neurociencias como en la Ciencias Sociales. En las Neurociencias se ha asumido la noción que el origen de la violencia es un hecho intraindividual, debido a desajustes neurobiológicos en el sujeto que le impiden controlar sus actos, mientras que en las Ciencias Sociales la violencia es explicable como la desadaptación de ciertos grupos o individuos al contexto y a los discursos en los cuales se hayan inmersos. Así planteadas, ambas perspectivas justifican a un Otro como única causa de la violencia padecida, hecho que impide tanto evidenciar otros tipos de actos que se realicen pueden y causan igual o mayor da o sin haber sido calificados como violentos, como hacer una crítica de la justificación que ofrecen tales investigaciones a discursos de dominación presentes en la sociedad donde se apliquen. Se propone, para las traducciones en lengua castellana el concepto agresión como base, primero para la correcta definición de tales actos en las disciplinas que se dedican a su estudio para así obtener una perspectiva holística de tales fenómenos y, segundo, permitir la inclusión de las definiciones sociales de agresión como medio para superar los discursos ideológicos y de dominación hasta ahora presentes en las investigaciones
Osteoporosis: un problema de salud en aumento Osteoporosis: a rising health problem
Rubén S Padrón Durán
Revista Cubana de Endocrinología , 2001,
Abstract:
In Vitro Characterization of the Efficacy and Safety Profile of a Proprietary Ajuga Turkestanica Extract  [PDF]
José M. Zubeldia, Aarón Hernández-Santana, Miguel Jiménez-del-Rio, Verónica Pérez-López, Rubén Pérez-Machín, José Manuel García-Castellano
Chinese Medicine (CM) , 2012, DOI: 10.4236/cm.2012.34031
Abstract:

Ajuga Turkestanica, an herbaceous flowering species in the mint family, has been traditionally used in Turkeyand Uzbekistan for heart disease, muscle aches and stomach problems. Due to its high levels of phytoecdysteroids (particularly the characteristic C-11-hydroxylated Turkesterone), anabolic properties have also been reported. The aim of our study was to screen for early signs of efficacy and safety of a proprietary Ajuga turkestanica extract (ATE) using in vitro models. C2C12 mouse myotube cell line was used to study potential effects on viability and gene modulation. Cell viability was evaluated with different concentrations [0.2 - 200 ppm (mg/L)] of ATE. Gene modulation was assessed by quantitative polymerase chain reaction (qRT-PCR) after 6h incubation (ATE vs. the androgenic anabolic steroid methandrostenolone). Total androgenic activity was measured using the A-SCREEN bioassay. Ultra-high performance liquid chromatography analysis showed good correlation between the phytochemical profile of the native plant and our ATE. C2C12 mouse myotube cells treated with ATE experienced no significant loss of viability (concentrations 0.2 - 200 ppm, 1 - 24 hs, p > 0.05). qRT-PCR array analysis showed significant (p < 0.05) down regulation of Caspase-3 (2-fold) and Myostatin (4-fold). The extract showed no androgenic activity within the dose range used. Our results indicate the potential for an ATE to support muscle mass without

Morbilidad en la consulta de endocrinología del Centro de Investigaciones Medicoquirúrgicas de Angola
Padrón Durán,Rubén S.; Guillén Pérez,Mayda;
Revista Cubana de Endocrinolog?-a , 2006,
Abstract: the data on morbidity at the outpatient department may be useful to know the causes for which the patients visit the health center, as well as to plan and provide special consultations and complementary tests. the objective of this study is to present and analyze morbidity at the endocrinology outpatient department of the center for medicosurgical research in angola. all the diagnoses of every case were collected for 28 months in a row. the specific diagnoses were classified into 7 big groups. 1) glycemia alterations, 2) obesity and other metabolic disorders, 3) reproductive medicine, 4) thryoid disorders, 5) pediatric endocrinology, 6) other endocrinopathies and 7) no endocrinopathies. 2 294 patients received medical attention. the most frequent diagnostic groups were type 2 diabetes mellitus (dm2) and exogenous obesity (53.01 and 24.72, respectively), followed by hyperlipoproteinemias (11.73). in a range between 4.5 and 10 %, we observed euthyroid diffuse goiter, altered fasting glycemia, female infertility and hyperuricemia. the rest was found in less than 3 % of the total of cases. the most important results and conclusions were the following: a) the most common diagnostic groups were glycemia alterations, obesity and other metabolic disorders, among them dm2 and exogenous obesity, b) the diagnoses of reproductive medicine and thyroid disorders were relatively frequent, c) the endocrine disorders at pediatric ages and other endocrinopathies were rare, d) the common endocrinometabolic disorders in other populations were unfrequent or non-existent reasons to seek medical attention, e) the results showed that the whole endocrinology care profile is not well known in this setting.
Morbilidad en la consulta de endocrinología del Centro de Investigaciones Medicoquirúrgicas de Angola Morbidity at the Endocrinology outpatient department of the Center for Medicosurgical Research in Angola
Rubén S. Padrón Durán,Mayda Guillén Pérez
Revista Cubana de Endocrinología , 2006,
Abstract: Los datos de la morbilidad en consulta externa pueden ser útiles para conocer las causas por las que los pacientes acuden al centro de salud, así como para planificar el ofrecimiento de consultas especiales y de exámenes complementarios. El objetivo de este estudio es presentar y analizar la morbilidad en la consulta externa de endocrinología del Centro de Investigaciones Medicoquirúrgicas de Angola (CIMECA). Se compilaron todos los diagnósticos de cada caso durante 28 meses consecutivos. Los diagnósticos específicos se clasificaron en 7 grandes grupos: 1) alteraciones de la glucemia, 2) obesidad y otros trastornos metabólicos, 3) medicina reproductiva, 4) trastornos del tiroides, 5) endocrinología pediátrica, 6) otras endocrinopatías y 7) sin endocrinopatías. Se atendieron 2 294 pacientes. Los grupos diagnósticos más frecuentes fueron: alteración de la glucemia (60,07) y obesidad y otros trastornos metabólicos (42,07); relativamente frecuentes fueron medicina reproductiva (19,4) y trastornos del tiroides (11,07). Sin embargo, los pacientes de endocrinología pediátrica (1,53) y otras endocrinopatías (0,22) fueron muy poco numerosos. Los diagnósticos específicos más comunes fueron la diabetes mellitus tipo 2 (DM2) y la obesidad exógena (53,01 y 24,72 respectivamente), seguidos por las hiperlipoproteinemias (11,73). En un rango entre 4,5 y 10 % observamos bocio difuso eutiroideo, glucemia en ayunas alterada, infertilidad femenina e hiperuricemia; el resto se halló en menos del 3 % del total de casos. Lo resultados y conclusiones más importantes del estudio son: a) Los grupos diagnósticos más comunes fueron las alteraciones de la glucemia y la obesidad y otros trastornos metabólicos, entre ellos la DM2 y la obesidad exógena, b) Los diagnósticos de medicina reproductiva y trastornos del tiroides fueron relativamente comunes, c) Los trastornos endocrinos en edades pediátricas y otras endocrinopatías fueron muy poco frecuentes, d) trastornos endocrinometabólicos comunes en otras poblaciones fueron motivo de consulta poco frecuentes o inexistentes, e) los resultados indican que en este medio no se conoce bien todo el perfil de atención de la endocrinología. The data on morbidity at the outpatient department may be useful to know the causes for which the patients visit the health center, as well as to plan and provide special consultations and complementary tests. The objective of this study is to present and analyze morbidity at the Endocrinology outpatient department of the Center for Medicosurgical Research in Angola. All the diagnoses of every case were coll
Reserva endocrina ovárica en mujeres con falla ovárica prematura
Padrón Durán,Rubén S.; Montejo Gómez,Lidermys;
Revista Cubana de Endocrinolog?-a , 2002,
Abstract: 19 women with premature ovarian failure that were seen at the physician's office due to secondary hypergonadotropic amenorrhea were studied to determine the existence of some degree of ovarian endocrine reserve. a detailed medical history was taken and complementary examinations were made to define the cause. the basal levels of follicle-stimulating hormone (fsh), luteinizing hormone (lh), estradiol (e2), prolactin (prl), and thyrotropin (tsh) were determined.the steroideal ovarian reserve was also determined by the dynamic test of hypophyseal inhibition of gonadotropins (gn) with ethynyl estradiol and, later, it was estimulated with gonadotropic menopausic hormone (gmh).the basal levels of fsh, lh, e2, testosterone (t) and androstenedione (a'd) were calculated during inhibition and after the stimulation with gmh. it was found that the mean basal levels of fsh were higher than those of lh, the levels of e2 were low and prl was normal on analyzing them as a group. the mean basal level of e2 was low and there was no increase of its mean levels after the stimulation with gmh. the mean basal levels of t were normal, unlike a'd that was low. no rise was observed poststimulation on being analyzed as a group. it was proved that 52.6 % of these patients have an ovarian estrogenic reserve, whereas only 20 % have an androgenic reserve. there were no important differences in the results of the dynamic test on dividing patients into 2 groups, according to the chronological age, time of amenorrhea and cause of pof, excepting that the reserve of t that was only found in those of idiopathic cause, which was not observed in those of immunological cause.
Gonadotropinas y sexoesteroides en mujeres posmenopáusicas del círculo de abuelos
Lozano álvarez,Elio; Padrón Durán,Rubén S; Seuc Jo,Armando;
Revista Cubana de Medicina General Integral , 1997,
Abstract: some of the factors that may influence the hormones of reporduction during the climaterium have been evaluated in recent publications. no research has been done in our country on this topic and that's why this study eas desingned aimed at knowing the relation existing between the postmenopausal hormonal levels sample of 134 postmenopausal women from an urban health area was taken and divided according to their participation in such a circle (67 in each group). the following hormones were detemined by radioimmunoassay: fsh, lh, porlactin, testosterone, estradiol, androstenedione and 17-hydroxyprogesterone (17 oh-p). prolactin was higher in those women who do not take part in the activities of the grandparents' circle; whereas testosterone and 17 oh-p were lower compared with the group participating in the activities. no difference was found in the rest of the hormones. according to these results the activities carried out by these women at the grandparents' circle influence the levels of some of the reproduction hormones, which may have favorable effects for health, on reducciong stress, and particularly on osteoporosis that appears during this period of life.
Caracterización de la lactancia materna en un área urbana
Ovies Carballo,Gisel; Santana Pérez,Felipe; Padrón Durán,Rubén S;
Revista Cubana de Medicina General Integral , 1999,
Abstract: a descriptive and cross-sectional study of 872 women who lived in an urban area and had given birth from 1 to 12 months before was conducted in order to know the duration, pattern of breast feeding, and the causes to abandon it. 1.1 % of these women never started breast feeding due to agalactia. women began to breast feed their children in an average time between 1 and 15 days. among those who had abandoned breast feeding at the time of the study the mean time of duration was 108.5 days. the life table technique was applied to the group that was not breast feeding so as to determine the continuity rate and the risk of leaving breast feeding. in the first case there is only 51 % of probability to continue lactating from 4 to 5 months, and in the same period the weaning risk is 0.83 %. the most frequent reason to leave this practice was the complete loss of milk. only 32.6 % of the studied population used breast feeding exclusively. it is concluded that there is a high trend to abandon breast feeding early and, mainly, the exclusive one
Reserva endocrina ovárica en mujeres con falla ovárica prematura Endocrine ovarian reserve in women with premature ovarian failure
Rubén S. Padrón Durán,Lidermys Montejo Gómez
Revista Cubana de Endocrinología , 2002,
Abstract: Se estudiaron 19 mujeres con falla ovárica prematura que acudieron a consulta por amenorrea secundaria hipergonadotrópica, para determinar en ellas la existencia de algún grado de reserva endocrina ovárica. Se confeccionó historia clínica minuciosa y exámenes complementarios para definir la causa. Se determinaron los niveles basales de hormona folículo estimulante (FSH), luteinizante (LH), estradiol (E2), prolactina (Prl) y tirotropina (TSH). Se determinó también reserva ovárica esteroidea mediante la prueba dinámica de inhibición hipofisaria de gonadotropinas (Gn) con etinilestradiol y, posteriormente, se estimuló con hormona gonadotrópica menopáusica (HMG), y se determinaron los niveles basales de FSH, LH, E2, testosterona (T) y androstenediona (A'd), durante la inhibición y posterior al estímulo con HMG. Se halló que los niveles basales medios de FSH fueron más altos que los LH; los de E2 fueron bajos y la Prl fue normal al analizarlas como grupo. El nivel medio de E2 basal fue bajo y no hubo aumento en los niveles medios del mismo posterior al estímulo con HMG. Los niveles medios basales de T fueron normales a diferencia de la A'd que fue baja, no se obtuvo aumento de los mismos posestímulo al analizarlas como grupo. Se comprobó que el 52,6 % de estas pacientes mantienen reserva ovárica estrogénica, mientras que sólo el 20 %, aproximadamente mantiene reserva androgénica. No hubo diferencias importantes en los resultados de la prueba dinámica al dividir a las pacientes en 2 grupos, según la edad cronológica, tiempo de amenorrea y causa de la FOP, excepto que solamente se halló reserva de T en las de causa idiopática, lo cual no se observó en las de causa inmunológica. 19 women with premature ovarian failure that were seen at the physician's office due to secondary hypergonadotropic amenorrhea were studied to determine the existence of some degree of ovarian endocrine reserve. A detailed medical history was taken and complementary examinations were made to define the cause. The basal levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), Prolactin (Prl), and Thyrotropin (TSH) were determined.The steroideal ovarian reserve was also determined by the dynamic test of hypophyseal inhibition of gonadotropins (Gn) with ethynyl estradiol and, later, it was estimulated with gonadotropic menopausic hormone (GMH).The basal levels of FSH, LH, E2, testosterone (T) and androstenedione (A'd) were calculated during inhibition and after the stimulation with GMH. It was found that the mean basal levels of FSH were higher than those of
Disfunción sexual eréctil Sexual erectile dysfunction
Jorge Luis Sell Lluveras,Rubén S Padrón Durán
Revista Cubana de Endocrinología , 2001,
Abstract:
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