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Quality of Scar after Total Thyroidectomy: A Single Blinded Randomized Trial Comparing Octyl-Cyanoacrylate and Subcuticular Absorbable Suture
Fabrizio Consorti,Rosaria Mancuso,Annalisa Piccolo,Eugenio Pretore,Alfredo Antonaci
ISRN Surgery , 2013, DOI: 10.1155/2013/270953
Abstract: Objective. To compare the quality of resulting scar at 6 weeks after total thyroidectomy with the use of the tissue adhesive octyl-cyanoacrylate or subcuticular absorbable suture for the closure of cervicotomy. Material and Methods. There are 50 patients undergoing a cervicotomy for total thyroidectomy. Twenty-five patients were randomly assigned to closure with tissue adhesive and 25 with subcuticular absorbable suture. At week 6 the scar was evaluated by blinded assessors with the Italian version of POSAS questionnaire, a validated wound scale composed of an observer’s and a patient’s subscale. Results. Assessment of scar appearance showed a statistically significant difference ( ) in favor of subcuticular suture with respect to tissue adhesive on observer’s assessment. The difference on patients’ self-assessment was not significant. A multivariate analysis of six qualitative features of scars showed a significant influence on assessment for hyperpigmentation and relief of scar. The Italian version of POSAS proved to be reliable. Conclusion. Though tissue adhesive represents a valid method of skin closure, subcuticular absorbable suture provides a better aesthetic outcome in small cervical incisions in the early phase after thyroid surgery. 1. Background Aesthetic outcome is particularly relevant in thyroid surgery since patients are mostly women and young adults and since the incision is in a highly sensitive and visible anatomic location. Cosmetic concern about the final scar appearance contributed to motivate the development of minimally invasive approaches for thyroid surgery and parathyroid surgery over the last decade [1–3]. Minimally invasive thyroid surgery techniques (MIT) are different but all share the same goals: reduction of tissue trauma, early hospital discharge, and better neck wound cosmetic appearance, while maintaining the same surgical outcome as traditional thyroidectomy [4]. In addition to MIT, methods of skin closure contribute to the overall aesthetic outcome and patient’s satisfaction. Methods of skin closure vary in published series and are largely the results of surgeon’s choice based upon the need for a rapid, economic, and reproducible technique [5]. Skin closure techniques include the use of the tissue adhesive octyl-cyanoacrylate, introduced 15 years ago in clinical practice as an ideal system of wound closure [6]. Many studies showed that tissue adhesive is an acceptable alternative to standard wound closure since it yields similar clinical and aesthetic results, even if early wound dehiscence occurs in the 1% to 5% of
The mathematics of McTaggart's paradox
Mancuso, Domenico;
Manuscrito , 2012, DOI: 10.1590/S0100-60452012000200003
Abstract: mc taggart's celebrated proof of the unreality of time is a chain of implications whose final step asserts that the a-series (i.e. the classification of events as past, present or future) is intrinsically contradictory. this is widely believed to be the heart of the argument, and it is where most attempted refutations have been addressed; yet, it is also the only part of the proof which may be generalised to other contexts, since none of the notions involved in it is specifically temporal. in fact, as i show in the first part of the paper, mctaggart's refutation of the a-series can be easily interpreted in mathematical terms; subsequently, in order to strengthen my claim, i apply the same framework by analogy to the cases of space, modality, and personal identity. therefore, either mctaggart's proof as a whole may be extended to each of these notions, or it must embed some distinctly temporal element in one of the steps leading up to the contradiction of the a-series. i conclude by suggesting where this element might lay, and by hinting at what i believe to be the true logical fallacy of the proof.
Budd-Chiari syndrome management: Lights and shadows
Andrea Mancuso
World Journal of Hepatology , 2011, DOI: 10.4254/wjh.v3.i10.262
Abstract: Budd-Chiari syndrome (BCS) is a rare disease whose management should follow a step by step strategy. Anticoagulation and medical therapy should be the first line treatment. Revascularization or TIPS are indicated in case of no response to medical therapy. OLT should be indicated as a rescue therapy and anticoagulation be started soon after OLT. However, no clear indication can actually be given about the timing of different treatments. Moreover, there is some concern about treatment of some subgroup of patients, especially regarding the risk of recurrence after liver transplantation. The topic of this paper is to critically review the actual knowledge of BCS management.
Hepatocellular carcinoma in thalassemia: A critical review
Andrea Mancuso
World Journal of Hepatology , 2010,
Abstract: Due to blood transfusions, thalassemics are often infected with either hepatitis C virus (HCV) or hepatitis B virus and often have hemochromatosis. Hepatocellular carcinoma (HCC) has emerged in thalassemics only recently as a result of the improvement in thalassemia outcomes. In fact, a prospective study estimated an HCC incidence in β-thalassemia of about 2%. Although data are scanty, HCC screening in thalassemics with risk factors for HCC should be carried out. HCV treatments have some efficacy in HCV infected thalassemics despite partial contraindication to ribavirin and iron overload. However, there are no data on how HCV treatment translates into HCC prevention. Preliminary data suggest that HCC treatment in thalassemics should generally have the same outcomes as in non-thalassemics. Although coexistence of severe comorbidities makes liver transplantation challenging, this therapeutic possibility should not be precluded for well selected HCC β-thalassemia patients. In fact, 2 transfusion dependent adult HCC β-thalassemia patients have recently undergone successful liver transplantation with a good outcome. In conclusion, HCC seems to be a developing issue in thalassemia and HCC screening should be carried out. HCC treatment, including liver transplantation, can be performed in selected patients. A multidisciplinary effort is needed for management.
Data Mining and Exploratory Data Analysis for the Evaluation of Job Satisfaction  [PDF]
Rosaria Lombardo, Ermelinda Della Valle
iBusiness (IB) , 2011, DOI: 10.4236/ib.2011.34050
Abstract: In this paper we face off the relationship value management which is a theme in the relationship marketing literature gaining increasing attention in the last decade. The main aim of this study is to evaluate job quality and in particular employees’ satisfaction of non-profit enterprises by using, among different exploratory data analysis tools, ordered multiple correspondence analysis which is a part of corporate data mining. We focus attention on Ordered Multiple Correspondence Analysis (OMCA), recently proposed in statistical literature, to monitor (dis)satisfaction in different times or spaces. In particular we present a new strategy based on OMCA which allows to deal with ordered variables (Likert items) taking into account other qualitative information of job (kind of job contract, type of incentives, etc.) affecting the overall satisfaction of employees.
Semilinear Venttsel’ Problems in Fractal Domains  [PDF]
Maria Rosaria Lancia, Paola Vernole
Applied Mathematics (AM) , 2014, DOI: 10.4236/am.2014.512175
Abstract: We study a semilinear parabolic problem with a semilinear dynamical boundary condition in an irregular domain with fractal boundary. Local existence, uniqueness and regularity results for the mild solution, are established via a semigroup approach. A sufficient condition on the initial datum for global existence is given.
The Effects of Low Cost Airlines Growth in Italy  [PDF]
Domenico Campisi, Roberta Costa, Paolo Mancuso
Modern Economy (ME) , 2010, DOI: 10.4236/me.2010.12006
Abstract: In recent years, low cost carriers (LCCs) have been the fastest growing sector of the aviation industry. The routes served by these carriers were undersized in comparison with principal routes, but deregulation made possible an efficient access to many new markets. The new generation of regional and low cost carriers have enabled a better matching of capacity to demand on routes previously served solely by large airlines, experiencing an increasing role in spatial development. Regional airports impact on local economies directly as a catalyst for other on-site economic activities and indirectly as a regional economic multiplier. This paper analyses the relation between LCC passenger traffic, secondary airports utilization and regional economic development. We underline that increased service at Italian secondary airports could affect economic development in the surrounding regions, including increased tourism and the potential for cluster development.
Eating Disorders and Menarche: Can Emotions toward the First Period Provide Insight into Future Eating Disorder Development?  [PDF]
Tara Beck, Alison Mancuso, Joanna Petrides
Psychology (PSYCH) , 2017, DOI: 10.4236/psych.2017.811113
Abstract: Objective: There is much ambiguity regarding Eating Disorder (ED) diagnosis, including when a patient actually develops the disease. Many studies have focused on behaviors during late adolescence as a crucial time for ED development, but few have focused on menarche. This study seeks to identify possible behavioral traits during menarche, including emotion toward the first period, which can be used as a warning sign for future ED development. Method: An anonymous online survey was distributed to approximately 1000 female students and faculty at Rowan University School of Osteopathic Medicine and 100 females on an ED Recovery Facebook group. The survey was created and responses were recorded using Rowan Qualtrics system in order to protect patient responses and ensure anonymity. Data was analyzed using SPSS. Results: There were many significant differences found in this study; feelings of fear (p = 0.009), sadness (p = 0.021) and disgust (p = 0.026) toward menarche were significantly higher in those who have been diagnosed with an ED. Additionally, ED patients felt significantly less prepared (p = 0.015) for the body changes that occurred during puberty. Those with an ED also experienced significantly increased focus on weight both prior to and during menarche, and reported an increased incidence of self-criticizing their weight to others (p < 0.001). Conclusion: The results of this study give insight into behavioral attributes, fear, sadness and disgust, toward a concrete event (menarche) which parents, pediatricians and even school teachers can use to detect early signs of ED behaviors. This provides insight into the development of future diagnostic criteria that caretakers can use to establish early intervention with young, at-risk females to prevent a future ED.
2nd society e la sfera di cristallo
Rosaria Conte
S&F_scienzaefilosofia.it , 2010,
Le virtù del pettegolezzo
Rosaria Conte
Storia delle Donne , 2011,
Abstract: In this work a theory of gossip as a means for social control is proposed. Exercising social control roughly means to isolate and/or to punish cheaters. However, punishment is costly and it inevitably implies the problem of second-order cooperation. Moving from a cognitive model of social control and gossip, data from ethnographic studies and agent-based simulations are reported on to support the claim that gossip reduces the costs of social control without lowering its efficacy. Considerations about the enticement of gossip, and the contribution of the two genders to its provision are included.
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