oalib

OALib Journal期刊

ISSN: 2333-9721

费用:99美元

投稿

时间不限

2019 ( 3 )

2018 ( 20 )

2017 ( 25 )

2016 ( 41 )

自定义范围…

匹配条件: “Rosa” ,找到相关结果约12032条。
列表显示的所有文章,均可免费获取
第1页/共12032条
每页显示
Can Purified Omega-3 Polyunsaturated Fatty Acids Supplementation Act Blood Pressure Levels in Untreated Normal-High Blood Pressure Subjects with Hypertriglyceridemia?  [PDF]
Maria Leonarda De Rosa
Pharmacology & Pharmacy (PP) , 2012, DOI: 10.4236/pp.2012.32031
Abstract: Omega-3 (ω-3) polyunsaturated fatty acids (PUFAs) from fish and fish oils appear to protect against coronary heart disease: their dietary intake is in fact inversely associated with cardiovascular disease morbidity/mortality in population studies. Recent evidence suggests that at least a part of this protective effect is mediated by a relatively small but significant decrease in blood pressure (BP) level. In fact, omega-3 PUFAs exhibit wide-ranging biological actions that include regulating both vasomotor tone and renal sodium excretion, partly competing with omega-6 PUFAs for common metabolic enzymes and thereby decreasing the production of vasoconstrictor rather than vasodilator and anti-inflammatory eicosanoids. PUFAs also reduce angiotensin-converting enzyme (ACE) activity, angiotensin II formation. We retrospectively evaluated the long-term effect of a omega-3 PUFAs supplementation on the blood pressure level of 91 hypertriglyceridemic subjects with untreated normal-high blood pressure that were prescribed a 3 grams omega-3 PUFAs supplementation in order to improve their plasma lipid pattern. After 24 months of treatment, systolic blood pressure (SBP) meanly decreased by 2.6 +/- 2.5 mmHg (p = 0.001) and diastolic blood pressure (DBP) by 1.4 +/- 3.1 mmHg (p < 0.001), while basal heart rate decreased by 4.1 +/- 4.6 bpm (p < 0.001). Both SBP and DBP reduction were significantly related to the baseline SBP (p < 0.001) and DBP (p < 0.001), respectively. Diastolic blood pressure change was also inversely related to the patient’s age (p = 0.004). No significant difference was perceived in the metabolic syndrome subgroup. In our retrospective study, highly purified omega-3 PUFAs long-term supplementation is associated with a significant reduction in SBP, DBP, and basal heart rate in hypertriglyceridemic patients with normal-high blood pressure. The main determinants of the omega-3 PUFAs anti-hypertensive effect appear to be the basal blood pressure level and age. Future research will clarify if omega-3 PUFAs supplementation could improve the antihypertensive action of specific blood pressure lowering drug classes and of statins.
Peri-implantitis and periodontitis: Use of bacteriological test in dental practice  [PDF]
Francesco Carinci, Rosa Maria Gaudio
Forensic Medicine and Anatomy Research (FMAR) , 2013, DOI: 10.4236/fmar.2013.13010
Abstract: Peri-implantitis has been defined as an inflamematory condition involving dental implants, surrounding mucosa and bone, which lose supporting bone. Although high success rates for endosseous implants have been reported, failures occur, and some implants are lost or removed. At least 10% of the failures have been suggested to be the result of peri-implantitis. One of the major causes of the peri-implantitis is the bacterial colonization of implant surfaces but additional risk factors such as periodontitis, poor oral hygiene, tobacco consumption, prepost operative therapies and genetic susceptibility should be considered. In the present study a real-time PCR bases assay was designed to detect and quantify red complex species, then used to investigate 307 periodontal pocket samples from 127 periodontitis patients and 180 controls. Results demonstrated a significant higher prevalence of red complex species and increased amount of Porphyromonas gingivalis and Treponema denticolain periodontal pocket of periodontitis. Since a higher risk of peri-implantitis occurs in periodontally affected patients, detection and treatment of bacteria is a fundamental objective to ensure dental implant survival.
Application of the New Moroccan Family Code in Spain (with a Gender Perspective)  [PDF]
Gloria Esteban de la Rosa
Beijing Law Review (BLR) , 2013, DOI: 10.4236/blr.2013.44019
Abstract:

The application of the Moroccan Family Code by Spanish legal operators is not simple, to the extent that it is not only a question of knowing its contents, but also, behind each of its articles and, relating to the institutions contained in the Code, there is a specific understanding of the world and, more specifically, family relations. The Spanish system of Private International Law is to serve as a “communication channel” between legislations which are beginning to coincide due to the new private international situations taking place in Spain, as a new foreign population begins to settle, in particular when it comes to female Moroccan immigrants. In these cases, Moroccan family law may be applied or considered by the Spanish authorities, favouring thus the recognition of decisions taken in Morocco.

Cultural Diversity, European Public Policy Exception and Family Law of Muslim Countries  [PDF]
Gloria Esteban de la Rosa
Beijing Law Review (BLR) , 2015, DOI: 10.4236/blr.2015.62015
Abstract: The recognition of cultural diversity as a value of the European Union Law is undoubtedly present in the current process of integration, which, in turn, is related to the maintenance of peace. Without prejudice to the treatment given by national regulations (Private International Law systems) of each Member State to the issue of cultural diversity existing in the current European society, it may be mentioned the positioning that has also been taken by the EU legislature of PIL on the treatment of said diversity. Tools used by the Private International Law system both for European Union Member States and for the European Private International Law system itself to give answers to this multiculturalism located in the territory that comprises the European Union Member States are discussed below. In particular, art. 10 of the Council Regulation (EU) no. 1259/2010, of 20 December 2010, implementing enhanced cooperation in the area of the law applicable to divorce and legal separation. This exception (public policy) will be practically operational in general when it comes to the implementation of the national system of an Islamic countries, because it may be considered that there is a difference between men and women in everything related to family relationships. The aim of this paper is to analyze the possibility of the “recognition method” as a clause for the interpretation of Private International Law to permit the application of foreign Muslim Law by European authorities in family cases and to avoid limping relationships.
The best of 2005 in echocardiography back from EuroEcho 9 – Florence, Italy
Rosa Sicari
Cardiovascular Ultrasound , 2006, DOI: 10.1186/1476-7120-4-11
Abstract: The Meeting of the European Association of Echocardiography (EuroEcho9) that took place in Florence from December 6th to 10th, has just finished achieving the record of abstract submissions and participant attendance (2.842). The interest on ultrasound technologies is very high and is still increasing over time in relation to its widespread employment, often outside the cardiological community. This is a brief report on what went on for those who could not attend the meeting or could not follow all the sessions.During the opening ceremony, the president Alan Fraser announced the result of the recent elections for a new member in the Board. The winner was Prof. Albert Varga from Szeged, Hungary. He has an outstanding curriculum characterized by some key publications on safety of stress echocardiography and evaluating new protocols for the detection of myocardial viability. His election is very welcome inside the Board since he represents an independent and highly appreciated voice of the new European Union countries. For the first time the Association employed a completely electronic voting system (different from the previous one that was conducted via e-mail). The electoral system employed by the Association allows that any echocardiographist from any associated country member (the membership of countries to the European Association does not correspond to the 25 members of the European Union but is much larger), can submit his/her resume to the Board. The candidatures do not go through a selection system unless more than five candidates apply for the same position, as stated in the bylaws of the Association. In that particular case the Board will select the best profiles that would fit for that position. The electronic vote posed some technical problems (many physicians found the access a little bit too complicated) but the time allowed for voting was long enough to overcome these limitations. This is an open and transparent way to have access to the Board independe
Relevance of tissue Doppler in the quantification of stress echocardiography for the detection of myocardial ischemia in clinical practice
Rosa Sicari
Cardiovascular Ultrasound , 2005, DOI: 10.1186/1476-7120-3-2
Abstract: Pharmacologic stress echocardiography is an established cost-effective technique for the detection of coronary artery disease [1]. The widespread use in the clinical practice has become possible only after evidence collected through large scale multicenter studies that demonstrated its feasibility, safety, diagnostic and prognostic accuracy [4-8]. According to the guidelines of ACC/AHA – pharmacological stress echocardiography with either dobutamine or dipyridamole is a class I indication (of documented effectiveness and usefulness) for the diagnosis of coronary artery disease and for the prognostic stratification of patients with known coronary artery disease [2,3]. Its major limitation is related to a high inter-observer variability and to operator-dependent expertise that might be overcome by an appropriate training and the use of strict reading criteria [9-11]. Nonetheless the hunt for an objective, operator-independent technique to be applied to the conventional black and white regional wall motion analysis remains a major goal in stress echocardiography. Tissue Doppler Imaging (TDI) provides a quantitative analysis of regional myocardial function through the analysis of myocardial velocities [12,13]. Since velocity imaging is confounded by influence from velocities in other segments, the TDI – based modalities strain and strain rate imaging have been introduced to measure regional shortening fraction and shortening rate, respectively [14] Is the application of Tissue Doppler Imaging to stress echocardiography the technique that will solve it all? According to major journals the answer is yes: the diagnostic accuracy of stress echocardiography improves with TDI when analyzed in comparison with visual assessment of wall motion analysis for the detection of inducible ischemia. Inducible ischemia quantified in a number without the approximations of visual assessment. However the enthusiasm showed by some investigators is not substantiated by scientific results. In
Anti-ischemic therapy and stress testing: pathophysiologic, diagnostic and prognostic implications
Rosa Sicari
Cardiovascular Ultrasound , 2004, DOI: 10.1186/1476-7120-2-14
Abstract: Anti-ischemic therapy, in particular beta-blockers, is the most commonly employed drug for the control of myocardial ischemia in patients with stable coronary artery disease. Its widespread use also in patients with suspected coronary artery disease has important practical, clinical diagnostic and prognostic implications because diagnostic tests are heavily influenced by its effects. The diagnostic and prognostic impact of anti-ischemic therapy on stress testing is largely ignored but not negligible. The issue raises several questions: How to evaluate patients at time of testing for myocardial ischemia? How to interpret a stress test performed on anti-ischemic therapy? Are the stressors employed for the detection of myocardial ischemia created equal in relation to the different classes of drugs used in clinical practice? Is stress testing able to assess the efficacy of medical therapy in patients with known coronary artery disease? Has the protection of anti-ischemic therapy on inducible myocardial ischemia any impact on long-term survival?The answer to all these issues relies on the mechanism through which myocardial ischemia is induced by the different stressors (exercise or pharmacologic such as dipyridamole and dobutamine) employed during stress testing. Test exploring organic coronary artery stenosis can induce ischemia by two basic mechanisms: 1. an increase in oxygen demand, exceeding the fixed supply and 2. flow maldistribution due to inappropriate coronary arteriolar triggered by a metabolic/pharmacologic stimulus [1]. The mechanism of increased demand can be easily fitted into the familiar concept framework of ischemia as a supply-demand mismatch, deriving from an increase in oxygen requirements in the presence of a fixed reduction in coronary flow reserve. The different stresses can determine increases in demand through different mechanisms (Fig. 1). In resting conditions, myocardial oxygen consumption is dependent mainly upon heart rate, inotropic state,
Perioperative risk stratification in non cardiac surgery: role of pharmacological stress echocardiography
Rosa Sicari
Cardiovascular Ultrasound , 2004, DOI: 10.1186/1476-7120-2-4
Abstract: Risk stratification before major vascular surgery is an everyday challenge for the clinical cardiologist. The prediction of events in this set of patients bears important implications, epidemiological, clinical and practical. In fact, the size of the problem is not negligible. Cardiovascular complications account for approximately half of all mortality after non cardiac surgery and are the leading cause of death in those patients [1]. Moreover, patients with peripheral vascular artery disease have a higher chance of dying for cardiac and cardiovascular causes compared to patients with no peripheral vessel disease [2]. When both severe and symptomatic peripheral vascular disease were present, the risk of death due to coronary artery disease was 10 to 15 times higher [2]. In this set of patients the incidence of hard cardiac events (myocardial infarction and death) in the post-operative period is higher when compared to other type of non cardiac surgery. These patients are not only at risk for perioperative events, but they are also subject to late hard cardiac events.The need of an effective risk stratification is to select patients in order to face safely the surgical procedure, by balancing the benefit of each procedure with the inherent risks. Once the aim of risk stratification is stated, i.e. the identification of patients with a high probability of experiencing a hard cardiac event, the criteria of selection have to be discussed.The lack of controlled and randomized trials designed to assess the best strategy of stratification for patient evaluation before major vascular non cardiac surgery brought to the definition of guidelines by the American Heart Association/American College of Cardiology [3]with the aim of: 1 – identify patients at extremely high risk in whom surgery should be canceled, or other less hazardous procedures should be considered; 2 – identify those patients in whom the optimization of medical therapy or a coronary revascularization before sur
A dimens?o urbano-regional na metropoliza??o contemporanea
Moura,Rosa;
EURE (Santiago) , 2012, DOI: 10.4067/S0250-71612012000300001
Abstract: the contemporary stage of latin american metropolization, supported by new information and communication technologies, makes evidence spatial configurations that transcend the concept of urban or urban agglomerate and incorporate the regional dimension, as hybrid categories. they are morpholically dense and discontinous, they have a high rate of economic and institutional polarization, a they show a confluence fluxes and a overlay of scales. based on analysis of this process in brazil and on the identification of what was denominated "urban-regional arrangements", this paper explores their nature, characteristics, and role in the country's insertion in the social division of labor it also suggests possible configurations of this same type in other countries of latin america.
Inversiones urbanas en el contexto de la competitividad y globalización: los eventos en Curitiba
Moura,Rosa;
EURE (Santiago) , 2003, DOI: 10.4067/S0250-71612003008600003
Abstract: the one-idea concept has prevailed over the choice of instruments, policies and urban investments, oriented by the option of inserting cities in the productive internationalization process. according as a natural action, such proceeding represents a mirror of intentions that transcend the local, being incorporated into the popular imaginary as a consensus. what effects does such understanding provoke in the urban space production and in the citizenship exercise? how has it been assimilated in metropolitan management, particularly in the case of curitiba -paradigmatic city on urban planning and environmental management efficacy? this paper deeps in technical, juridical and institutional implications on metropolitan space adaptations to receive the recent investments projects -commercial, industrial and the real state ones. the overview of hidden events under this emblematic city appearance may subside a new way of urban management definition, drawing a participative and including city, ready to carry out a new urbanity.
第1页/共12032条
每页显示


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.