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Search Results: 1 - 10 of 1672 matches for " Rongsheng Ruan "
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Current Status and Prospects of Biodiesel Production from Microalgae
Xiaodan Wu,Rongsheng Ruan,Zhenyi Du,Yuhuan Liu
Energies , 2012, DOI: 10.3390/en5082667
Abstract: Microalgae represent a sustainable energy source because of their high biomass productivity and ability to remove air and water born pollutants. This paper reviews the current status of production and conversion of microalgae, including the advantages of microalgae biodiesel, high density cultivation of microalgae, high-lipid content microalgae selection and metabolic control, and innovative harvesting and processing technologies. The key barriers to commercial production of microalgae biodiesel and future perspective of the technologies are also discussed.
Automated NMR Fragment Based Screening Identified a Novel Interface Blocker to the LARG/RhoA Complex
Jia Gao, Rongsheng Ma, Wei Wang, Na Wang, Ryan Sasaki, David Snyderman, Jihui Wu, Ke Ruan
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0088098
Abstract: The small GTPase cycles between the inactive GDP form and the activated GTP form, catalyzed by the upstream guanine exchange factors. The modulation of such process by small molecules has been proven to be a fruitful route for therapeutic intervention to prevent the over-activation of the small GTPase. The fragment based approach emerging in the past decade has demonstrated its paramount potential in the discovery of inhibitors targeting such novel and challenging protein-protein interactions. The details regarding the procedure of NMR fragment screening from scratch have been rarely disclosed comprehensively, thus restricts its wider applications. To achieve a consistent screening applicable to a number of targets, we developed a highly automated protocol to cover every aspect of NMR fragment screening as possible, including the construction of small but diverse libray, determination of the aqueous solubility by NMR, grouping compounds with mutual dispersity to a cocktail, and the automated processing and visualization of the ligand based screening spectra. We exemplified our streamlined screening in RhoA alone and the complex of the small GTPase RhoA and its upstream guanine exchange factor LARG. Two hits were confirmed from the primary screening in cocktail and secondary screening over individual hits for LARG/RhoA complex, while one of them was also identified from the screening for RhoA alone. HSQC titration of the two hits over RhoA and LARG alone, respectively, identified one compound binding to RhoA.GDP at a 0.11 mM affinity, and perturbed the residues at the switch II region of RhoA. This hit blocked the formation of the LARG/RhoA complex, validated by the native gel electrophoresis, and the titration of RhoA to 15N labeled LARG in the absence and presence the compound, respectively. It therefore provides us a starting point toward a more potent inhibitor to RhoA activation catalyzed by LARG.
The Surface Friction and the Flow over Mountain
Wu Rongsheng,
Wu
,Rongsheng

大气科学进展 , 1991,
Abstract: The flow over mountain is quite complicated. There are a lot of papers on this problem and a lot of progresses have been made. However, in the most of these papers, just the dynamics contributions of mountain have been ana-lysed; the effect of the friction is often neglected. Since the frictional effect is always associated with flow, especially when it flows over the mountain. The study shows that the friction is small in the magnitude but it is not a negligible effect because it changes the features of the flow. In the case of super-or sub-critical flow, there are two extremes: one maximum, one minimum of the fluid surface on the lee-side of the mountain, while in the inviscid fluid, there is just one extreme. The frictional effect should neither be too strong nor too weak to make the situation happened ac-cording to the investigation of this paper.
Complete Solutions to Mixed Integer Programming  [PDF]
Ning Ruan
American Journal of Computational Mathematics (AJCM) , 2013, DOI: 10.4236/ajcm.2013.33B005
Abstract:

This paper considers a new canonical duality theory for solving mixed integer quadratic programming problem. It shows that this well-known NP-hard problem can be converted into concave maximization dual problems without duality gap. And the dual problems can be solved, under certain conditions, by polynomial algorithms.

The Internal Structure of Sha-henda: A Morphological Perspective  [PDF]
Jiacing Ruan
Open Journal of Modern Linguistics (OJML) , 2014, DOI: 10.4236/ojml.2014.44045
Abstract: Sha-henda (殺很大) “kill-very-big” which is coined from an advertisement of an on-line game has been being recently very popular in Taiwan society. With the effect of this slogan, people tends to analogize more and more new expressions, for example: sheng-henda (省很大) “save-very-big”, shui-henda (睡很大) “sleep-very-big”, and etc. Until 2013, the quantity of the coined expressions is still increasing. In the previous studies of Shen (2009), Xiao (2009), Liu (2010) and Liu (2012) on the structure of X-henda (X-很大), the structure is highly productive, involves an extreme or exaggerative meaning, is featured of rising tone, stress, and lengthening, and is initiated with a verb or an adjective. This present study argues henda in X-henda is a bound form (or a particle (助詞); Chao, 1979), similar to qilai (起來) in X-qilai or bude (不得) in X-bude, especially without objects or objects-preceding. With Distributed Morphology, a derivational analysis of the X-henda structure indicates that the function of henda intensifies the effect of sha to the extreme degree with rising tone, stress and lengthening to perform exaggeration on the object (in a sentence). The results may further contribute to grammaticalization analyses, verb-complement structure analyses and Chinese language teaching.
Early Warning Effect of “Wearing Cap” and “Catching Cap” on the Company’s Risk Structure
—Empirical Research Based on Breakpoint Regression Design
 [PDF]

Shuai Ruan
Modern Economy (ME) , 2019, DOI: 10.4236/me.2019.103068
Abstract: This paper takes the listed companies in China from 2010 to 2015 as samples, which uses the breakpoint regression design to analyze the change of risk structure and its possible mechanism of listed companies after wearing and removing hats. The results show that the short-term solvency of listed companies deteriorates after wearing hats, and the long-term liabilities increase significantly. R&D expenditure decreased significantly, and cash flow level deteriorated. Financial leverage and comprehensive leverage increased significantly, and the total market value of the company decreased significantly, which led to a significant deterioration in the short-term financial risk structure of the company after wearing a hat.
THE INFLUENCES OF OROGRAPHY UPON THE FLOW WITHIN EKMAN BOUNDARY LAYER UNDER THE APPROXIMATION OF GEOSTROPHIC MOMENTUM

Wu Rongsheng,

大气科学进展 , 1985,
Abstract: In this paper, the influences of orography on the boundary layer flow with the approximation of geostrophic momentum are studied. The wind velocity at the lower boundary will not always be zero when the orography exists. So the structure of the boundary layer flow, as well as the vertical velocity at the top of the boundary layer, is affected. There are three factors affecting the vertical motion at the top of the boundary layer: lifting due to orography; divergence due to Ekman flow, and advection of the geostrophic momentum. These effects and the features of the flow within the boundary layer are discussed in detail.
Problems in Library Construction of Newly-upgraded Local Undergraduate Institutions
Chunlan Qiu,Rongsheng Wen
International Education Studies , 2008, DOI: 10.5539/ies.v1n1p110
Abstract: Based on an analysis on the features and problems in the libraries of some newly-upgraded local undergraduate institutions, this article finally comes to a series of management countermeasures.
Helicity dynamics of atmospheric flow
Helicity Dynamics of Atmospheric Flow

Tan Zhemin,Wu Rongsheng,
Tan Zhemin
,Wu Rongsheng

大气科学进展 , 1994,
Abstract: Helicity is an important physical variable which is similar to the energy and enstrophy in three-dimensional fluid. It can be used to describe the motion in the direction of fluid rotation and also can be regarded as a new physical variable ill turbulence theory. In recent years, it has been used in atmospheric dynamics. In this paper, helicity of atmospheric flow, especially helicity in the boundary layer and in the vicinity of front was discussed. These results show that helicity is usually positive in the boundary layer due to the effect of friction. The helicity of boundary layer flow is larger in anticyclone than that in cyclone, resulting from the different wind structures of boundary layers in anticyclone and cyclone under the geostrophic momentum approximation. It is possible that the helicity is negative at certain height in the baroclinic boundary layer. The influences of nonlinearity and baroclinity on the helicity are important. The so called "Cloud Street" in the boundary layer is related to the dynamics of helicity. Helicity in the atmosphere can be expressed as the temperature advection under some conditions, so helicity would be allowed to describe the frontogenesis and development of frontal structure. The amplitude of helicity increases with time in the frontogenesis. A large gradient of helicity is generated in the region located to the northeast of the surface low and in which the front is formed. In warm frontal region, as well as behind the trough of temperature, the felicity is positive, while the helicity is negative in cold frontal sector and in the ahead ridge of temperature. The largest helicity occurs in the boundary.
Topographic Effect on Geostrophic Adjustment and Frontogenesis
地形对地转适应和锋生的影响

Fang Juan,Wu Rongsheng,
Fang Juan
,Wu Rongsheng

大气科学进展 , 2001,
Abstract: Three conservative principles: potential vorticity, absolute momentum and potential temperature are used to study the influence of topography on the local frontogenesis and geostrophic adjustment, which are induced by the inhomogeneous thermal fields. It is found that the horizontal distribution of the initial potential temperature and its position relative to the mountain play important roles during the geostrophic adjustment and local frontogenesis. The frontogenesis is weakened by the mountain when the initial thermal perturbation is located at the base of the upwind slope. The frontal discontinuity cannot occur unless the horizontal contrast of the initial potential temperature is great enough. Whereas, the situation is opposite when the initial thermal disturbance is mainly situated near the peak of the mountain. Complementary to the aforementioned cases, the effect of topography on the frontogenesis depends on the stratification of the flow when the initial thermal disturbance lies at the foot of lee slope. For weak stratification, topography is favorable to the formation of frontal discontinuity, vice versa. This discrepancy is attributed to the difference of subsidence warming, caused by the mountain, when the stratification is either strong or weak. Furthermore, the energy conversion ratio between the kinetic and potential energy during the geostrophic adjustment process is also affected by the topography. In contrast to the flat bottom case, the ratio is reduced (increased) when the initial thermal perturbation lies in the up-wind slope (lee slope). The reason is that the gravity force does negative work in the former case while does positive work in the latter case.
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