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Search Results: 1 - 10 of 302504 matches for " Ronald J. Moore "
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Crossed complexes, and free crossed resolutions for amalgamated sums and HNN-extensions of groups
Ronald Brown,Emma J. Moore,Timothy Porter,Christopher D. Wensley
Mathematics , 2002,
Abstract: The category of crossed complexes gives an algebraic model of CW-complexes and cellular maps. Free crossed resolutions of groups contain information on a presentation of the group as well as higher homological information. We relate this to the problem of calculating non-abelian extensions. We show how the strong properties of this category allow for the computation of free crossed resolutions for amalgamated sums and HNN-extensions of groups, and so obtain computations of higher homotopical syzygies in these cases.
Tevatron Collider Status and Prospects
Ronald S. Moore
Physics , 2009,
Abstract: The Tevatron proton-antiproton collider at Fermilab continues operation as the world's highest energy particle accelerator by delivering luminosity at a center-of-mass energy of 1.96 TeV. We review recent performance and plans for the remainder of Run 2.
Experiences Analyzing Faults in a Hybrid Distributed System with Access Only to Sanitized Data  [PDF]
Ronald J. Leach
Journal of Software Engineering and Applications (JSEA) , 2010, DOI: 10.4236/jsea.2010.35050
Abstract: In this paper we report on a work in progress assessing the faults observed and reported in a distributed, safety-critical, largely embedded system with both electrical and mechanical components. We illustrate why standard software testing techniques are not sufficient and indicate some of the technical and non-technical problems encountered in examining the faults and the initial results obtained. While the application domain is elevator operation, the techniques described here are general enough to apply to many other domains. Much of the data analyzed here would be considered imprecise in the software industry if it were used in software testing or to help increase fault tolerance. The paper includes a discussion of the use of multiple views of data, assessment of missing data, and analysis of informal information to produce its conclusions about fault avoidance and fault tolerance.
Extraction of Perchlorate Using Porous Organosilicate Materials
Brandy J. Johnson,Iwona A. Leska,Brian J. Melde,Ronald L. Siefert,Anthony P. Malanoski,Martin H. Moore,Jenna R. Taft,Jeffrey R. Deschamps
Materials , 2013, DOI: 10.3390/ma6041403
Abstract: Sorbent materials were developed utilizing two morphological structures, comprising either hexagonally packed pores (HX) or a disordered pore arrangement (CF). The sorbents were functionalized with combinations of two types of alkylammonium groups. When capture of perchlorate by the sorbents was compared, widely varying performance was noted as a result of differing morphology and/or functional group loading. A material providing improved selectivity for perchlorate over perrhenate was synthesized with a CF material using N-trimethoxysilylpropyl- N, N, N-trimethylammonium chloride. Materials were applied in batch and column formats. Binding isotherms followed the behavior expected for a system in which univalent ligands of varying affinity compete for immobilized sites. Performance of the sorbents was also compared to that of commercial Purolite materials.
Enhanced top-down characterization of histone post-translational modifications
Zhixin Tian, Nikola Toli?, Rui Zhao, Ronald J Moore, Shawna M Hengel, Errol W Robinson, David L Stenoien, Si Wu, Richard D Smith, Ljiljana Pa?a-Toli?
Genome Biology , 2012, DOI: 10.1186/gb-2012-13-10-r86
Abstract: Histones are important chromatin proteins that act as spools to package and order DNA into structural and manageable chromosomes. Core histones are modified by multiple post-translational modifications (PTMs) such as lysine acetylation, lysine or arginine methylation, and serine or threonine phosphorylation, among others. These PTMs generate a 'histone code' [1] that is implicated in chromatin-related cellular processes [2] including transcription [3], replication [4], repair [5], and alternative splicing [6].Although core histones comprise only four families (H4, H2B, H2A, and H3), each family has thousands of potential isoforms generated by different combinations of PTMs and protein sequence variation. Traditional antibody-based methods target specific isoforms, typically analyzing one PTM at a time, which makes it virtually impossible to measure combinatorial modifications occurring within the same histone molecule. Recently, high-throughput bottom-up [7] and middle-down [8] proteomic methods demonstrated potential for global characterization of PTMs on histone tails. However, these methods are ill-suited for characterizing multiple PTMs dispersed along the entire protein sequence that have been previously discovered to have significant participation in chromatin regulation [2,9-11].Top-down proteomic and high-throughput approaches are clearly required to identify and quantify the modulation of multiple intra-molecular histone modifications that synergistically regulate histone functions. Recently, a global top-down study demonstrated the feasibility of intact protein analysis for this purpose by identifying more than 300 histone isoforms using extensive fractionation and customized bioinformatics for global proteome characterization [12]. In histone-focused studies, top-down approaches using an offline two-dimensional liquid chromatography (2D LC) separation and Fourier transform mass spectrometry (FTMS) characterized 34 H4 isoforms from approximately 150 μg of
A Real Options Approach to Distressed Property Borrower-Lender Reconciliation  [PDF]
David J. Moore, Nuriddin Ikromov
Journal of Mathematical Finance (JMF) , 2015, DOI: 10.4236/jmf.2015.51007
Abstract: We propose a real option framework to value distressed properties and restructure their loans. Our approach reconciles the interests of borrowers and lenders through a constrained optimization model yielding mutually beneficial restructure terms. Borrowers receive lower loan balances and payments, while lenders replace non-performing loans with performing loans that have higher market values. A numerical illustration shows that the market value of a restructured loan can exceed that of the original non-performing loan and the post-foreclosure cash flows when the lender repossesses the property.
Addressing Adult Medicine Inpatients at the Community Level  [PDF]
Ronald J. Lagoe, Shelly Littau
Advances in Bioscience and Biotechnology (ABB) , 2015, DOI: 10.4236/abb.2015.65037
Abstract: This study evaluated the impact of adult medicine patients on hospital utilization in Syracuse, New York, a small metropolitan area including three urban hospitals. The study data indicated that the principal source of adult medicine patients, in hospital emergency departments, increased by 19 percent between 2010 and 2014. Another analysis showed that adult medicine discharges comprised the largest inpatient population and were closely correlated with changes in total discharges. The data also suggested that adult medicine patients were associated with excess inpatient stays when compared with national averages between 2010 and 2014 and that these excess days were difficult to eliminate. The study data also suggested that adult medicine patients were a major source of medical and surgical readmissions. The study identified the importance of adult medicine patients and suggested the need for further evaluation of this population.
Beam instrumentation for the Tevatron Collider
Ronald S. Moore,Andreas Jansson,Vladimir Shiltsev
Physics , 2010, DOI: 10.1088/1748-0221/4/12/P12018
Abstract: The Tevatron in Collider Run II (2001-present) is operating with six times more bunches and many times higher beam intensities and luminosities than in Run I (1992-1995). Beam diagnostics were crucial for the machine start-up and the never-ending luminosity upgrade campaign. We present the overall picture of the Tevatron diagnostics development for Run II, outline machine needs for new instrumentation, present several notable examples that led to Tevatron performance improvements, and discuss the lessons for future colliders.
Overview of the Tevatron Collider Complex: Goals, Operations and Performance
Stephen Holmes,Ronald S. Moore,Vladimir Shiltsev
Physics , 2011, DOI: 10.1088/1748-0221/6/08/T08001
Abstract: For more than two decades the Tevatron proton-antiproton collider was the centerpiece of the world's high energy physics program. The collider was arguably one of the most complex research instruments ever to reach the operation stage and is widely recognized for numerous physics discoveries and for many technological breakthroughs. In this article we outline the historical background that led to the construction of the Tevatron Collider, the strategy applied to evolution of performance goals over the Tevatron's operational history, and briefly describe operations of each accelerator in the chain and achieved performance.
The information content of gravitational wave harmonics in compact binary inspiral
Ronald W. Hellings,Thomas A. Moore
Physics , 2002, DOI: 10.1088/0264-9381/20/10/321
Abstract: The nonlinear aspect of gravitational wave generation that produces power at harmonics of the orbital frequency, above the fundamental quadrupole frequency, is examined to see what information about the source is contained in these higher harmonics. We use an order (4/2) post-Newtonian expansion of the gravitational wave waveform of a binary system to model the signal seen in a spaceborne gravitational wave detector such as the proposed LISA detector. Covariance studies are then performed to determine the ultimate accuracy to be expected when the parameters of the source are fit to the received signal. We find three areas where the higher harmonics contribute crucial information that breaks degeneracies in the model and allows otherwise badly-correlated parameters to be separated and determined. First, we find that the position of a coalescing massive black hole binary in an ecliptic plane detector, such as OMEGA, is well-determined with the help of these harmonics. Second, we find that the individual masses of the stars in a chirping neutron star binary can be separated because of the mass dependence of the harmonic contributions to the wave. Finally, we note that supermassive black hole binaries, whose frequencies are too low to be seen in the detector sensitivity window for long, may still have their masses, distances, and positions determined since the information content of the higher harmonics compensates for the information lost when the orbit-induced modulation of the signal does not last long enough to be apparent in the data.
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