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Search Results: 1 - 10 of 781 matches for " Rodney Givney "
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A Novel Bocavirus Associated with Acute Gastroenteritis in Australian Children
Jane L. Arthur ,Geoffrey D. Higgins,Geoffrey P. Davidson,Rodney C. Givney,Rodney M. Ratcliff
PLOS Pathogens , 2009, DOI: 10.1371/journal.ppat.1000391
Abstract: Acute gastroenteritis (AGE) is a common illness affecting all age groups worldwide, causing an estimated three million deaths annually. Viruses such as rotavirus, adenovirus, and caliciviruses are a major cause of AGE, but in many patients a causal agent cannot be found despite extensive diagnostic testing. Proposing that novel viruses are the reason for this diagnostic gap, we used molecular screening to investigate a cluster of undiagnosed cases that were part of a larger case control study into the etiology of pediatric AGE. Degenerate oligonucleotide primed (DOP) PCR was used to non-specifically amplify viral DNA from fecal specimens. The amplified DNA was then cloned and sequenced for analysis. A novel virus was detected. Elucidation and analysis of the genome indicates it is a member of the Bocavirus genus of the Parvovirinae, 23% variant at the nucleotide level from its closest formally recognized relative, the Human Bocavirus (HBoV), and similar to the very recently proposed second species of Bocavirus (HBoV2). Fecal samples collected from case control pairs during 2001 for the AGE study were tested with a bocavirus-specific PCR, and HBoV2 (sequence confirmed) was detected in 32 of 186 cases with AGE (prevalence 17.2%) compared with only 15 controls (8.1%). In this same group of children, HBoV2 prevalence was exceeded only by rotavirus (39.2%) and astrovirus (21.5%) and was more prevalent than norovirus genogroup 2 (13.4%) and adenovirus (4.8%). In a univariate analysis of the matched pairs (McNemar's Test), the odds ratio for the association of AGE with HBoV2 infection was 2.6 (95% confidence interval 1.2–5.7); P = 0.007. During the course of this screening, a second novel bocavirus was detected which we have designated HBoV species 3 (HBoV3). The prevalence of HBoV3 was low (2.7%), and it was not associated with AGE. HBoV2 and HBoV3 are newly discovered bocaviruses, of which HBoV2 is the thirdmost-prevalent virus, after rotavirus and astrovirus, associated with pediatric AGE in this study.
Estimating the Disease Burden of Pandemic (H1N1) 2009 Virus Infection in Hunter New England, Northern New South Wales, Australia, 2009
Fatimah S. Dawood,Kirsty G. Hope,David N. Durrheim,Rodney Givney,Alicia M. Fry,Craig B. Dalton
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0009880
Abstract: On May 26, 2009, the first confirmed case of Pandemic (H1N1) 2009 virus (pH1N1) infection in Hunter New England (HNE), New South Wales (NSW), Australia (population 866,000) was identified. We used local surveillance data to estimate pH1N1-associated disease burden during the first wave of pH1N1 circulation in HNE.
Should there be a standardised approach to the diagnostic workup of suspected adult encephalitis? a case series from Australia
Clare Huppatz, Yash Gawarikar, Chris Levi, Paul M Kelly, David Williams, Craig Dalton, Peter Massey, Rodney Givney, David N Durrheim
BMC Infectious Diseases , 2010, DOI: 10.1186/1471-2334-10-353
Abstract: A retrospective clinical audit was performed, of all adult encephalitis presentations between July 1998 and December 2007 to the three hospitals with adult neurological services in the Hunter New England area, northern New South Wales, Australia. Case notes were examined for evidence of relevant history taking, clinical features, physical examination, laboratory and neuroradiology investigations, and outcomes.A total of 74 cases were included in the case series. Amongst suspected encephalitis cases, presenting symptoms and signs included fever (77.0%), headache (62.1%), altered consciousness (63.5%), lethargy (32.4%), seizures (25.7%), focal neurological deficits (31.1%) and photophobia (17.6%). The most common diagnostic laboratory test performed was cerebrospinal fluid (CSF) analysis (n = 67, 91%). Herpes virus polymerase chain reaction (n = 53, 71.6%) and cryptococcal antigen (n = 46, 62.2%) were the antigenic tests most regularly performed on CSF. Neuroradiological procedures employed were computerized tomographic brain scanning (n = 68, 91.9%) and magnetic resonance imaging of the brain (n = 35, 47.3%). Thirty-five patients (47.3%) had electroencephalograms. The treating clinicians suspected a specific causative organism in 14/74 cases (18.9%), of which nine (12.1%) were confirmed by laboratory testing.The diagnostic assessment of patients with suspected encephalitis was not standardised. Appropriate assessment is necessary to exclude treatable agents and identify pathogens warranting public health interventions, such as those transmitted by mosquitoes and those that are vaccine preventable. An algorithm and guidelines for the diagnostic workup of encephalitis cases would assist in optimising laboratory testing so that clinical management can be best tailored to the pathogen, and appropriate public health measures implemented.Encephalitis is an uncommon but important clinical and public health syndrome. Clinically, the diagnosis is frequently difficult, treatme
Including the public in pandemic planning: a deliberative approach
Annette J Braunack-Mayer, Jackie M Street, Wendy A Rogers, Rodney Givney, John R Moss, Janet E Hiller, Flu Views team
BMC Public Health , 2010, DOI: 10.1186/1471-2458-10-501
Abstract: Two deliberative forums were carried out with members of the South Australian community. The forums were supported by a qualitative study with adults and youths, systematic reviews of the literature and the involvement of an extended group of academic experts and policy makers. The forum discussions were recorded with simultaneous transcription and analysed thematically.Participants allocated scarce resources of antiviral drugs and pandemic vaccine based on a desire to preserve society function in a time of crisis. Participants were divided on the acceptability of social distancing and quarantine measures. However, should such measures be adopted, they thought that reasonable financial, household and psychological support was essential. In addition, provided such support was present, the participants, in general, were willing to impose strict sanctions on those who violated quarantine and social distancing measures.The recommendations from the forums suggest that the implementation of pandemic plans in a severe pandemic will be challenging, but not impossible. Implementation may be more successful if the public is engaged in pandemic planning before a pandemic, effective communication of key points is practiced before and during a pandemic and if judicious use is made of supportive measures to assist those in quarantine or affected by social isolation measures.The emergence of a novel human influenza A (H1N1), early in 2009, saw the implementation of national pandemic influenza (PI) plans around the world. These plans had been developed, at the urging of the World Health Organisation (WHO), partly in response to the emergence of a virulent Avian Influenza A (H5N1) and partly in response to the 2003 outbreak of Severe Acute Respiratory Syndrome (SARS), both of which demonstrated gaps in global and local responses to infectious, clinically severe respiratory diseases.National plans [1] place considerable emphasis on stockpiles of antiviral drugs and prototype vaccines
Using the Analytical Hierarchy Process Model in the Prioritization of Information Assurance Defense In-Depth Measures?—A Quantitative Study  [PDF]
Rodney Alexander
Journal of Information Security (JIS) , 2017, DOI: 10.4236/jis.2017.83011
Abstract: Organizational computing devices are increasingly becoming targets of cyber-attacks, and organizations have become dependent on the safety and security of their computer networks and their organizational computing devices. Business and government often use defense in-depth information assurance measures such as firewalls, intrusion detection systems, and password procedures across their enterprises to plan strategically and manage IT security risks. This quantitative study explores whether the analytical hierarchy process (AHP) model can be effectively applied to the prioritization of information assurance defense in-depth measures. In response to these threats, the President, legislators, experts, and others have characterized cyber security as a pressing national security issue. The methods used in this study consisted of emailing study participants a survey requesting that they prioritize five defense in-depth information assurance measures, anti-virus, intrusion detection, password, smart-cards, and encryption, with a range of responses from 1 - 5 using a Likert scale to consider standard cost, effectiveness, and perceived ease of use in terms of protection of organizational computing devices. The measures were then weighted, based on ranking. A pair-wise comparison of each of the five measures is then made using AHP to determine whether the Likert scale and the AHP model could be effectively applied to the prioritization of information assurance measures to protect organizational computing devices. The findings of the research reject the H0 null hypothesis that AHP does not affect the relationship between the information technology analysts’ prioritization of five defense in-depth dependent variables and the independent variables of cost, ease of use, and effectiveness in protecting organizational devices against cyber-attacks.
A Study of the Simple Geometrical Relationship of the Main Monuments of Giza and a Possible Connection to Stars  [PDF]
Rodney Hale, Andrew Collins
Archaeological Discovery (AD) , 2016, DOI: 10.4236/ad.2016.42007
Abstract: There have been many books and articles written with the purpose of trying to express an underlying master plan for the major pyramids of the Giza plateau. In this paper, a simple yet accurate geometrical layout, which also includes the Sphinx monument, is demonstrated with the aid of a well-known and widely used computer program. Furthermore, the positions of stars may be added to the same program, enabling the correlation of star positions to pyramids during the time frame of their construction to be determined with accuracy and simplicity.
Nanorobotic Agents Communication Using Bee-Inspired Swarm Intelligence  [PDF]
Rodney Mushining, Francis Joseph Ogwu
Wireless Sensor Network (WSN) , 2013, DOI: 10.4236/wsn.2013.510024

The main goal of this paper is to design nanorobotic agent communication mechanisms which would yield coordinated swarm behavior. Precisely we propose a bee-inspired swarm control algorithm that allows nanorobotic agents communication in order to converge at a specific target. In this paper, we present experiment to test convergence speed and quality in a simulated multi-agent deployment in an environment with a single target. This is done to measure whether the use of our algorithm or random guess improves efficiency in terms of convergence and quality. The results attained from the experiments indicated that the use of our algorithm enhance the coordinated movement of agents towards the target compared to random guess.

Custeio baseado em atividades (ABC) aplicado aos processos de compra e venda de distribuidora de mercadorias
Wernke, Rodney;
Revista Contabilidade & Finan?as , 2005, DOI: 10.1590/S1519-70772005000200007
Abstract: this case study discussed the application of activity-based costing (abc) in a merchandise distribution company and aimed to identify the effective consumption of purchase and sales process resources by the three main market segments the entity is active in, so as to improve its profitability analysis. after a literature review on the main aspects of abc, the case study was described. first, the study company was characterized. next, the details of abc implementation were presented, including what procedures were realized for this purpose. finally, the most relevant management information obtained through this costing method were mentioned.
Persistent failure of the COIDA system to compensate occupational disease in South Africa
Rodney Ehrlich
South African Medical Journal , 2012,
Abstract: Cases of occupational disease, solvent encephalopathy and occupational asthma are used to exemplify failings of the workers’ compensation system in South Africa, that include delays in processing claims, non-response to requests for information, and inadequate assessment of disability. These and other systemic deficiencies in administration of the Compensation for Occupational Injuries and Diseases Act of 1993 (COIDA) reduce access by workers with occupational disease to private medical care, and shift costs to workers and to public sector medical care. Another unintended effect is to promote under-reporting of occupational disease by employers and medical practitioners. Reforms have been tried or proposed over the years, including decentralisation of medical assessment to specialised units, which showed promise but were closed. Improved annual performance reporting by the Compensation Commissioner on the processing of occupational disease claims would promote greater public accountability. Given the perennial failings of the system, a debate on outsourcing or partial privatisation of COIDA’s functions is due. S Afr Med J 2012;102:95-97.
Gay and Lesbian Issues and Psychology Review , 2007,
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