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Search Results: 1 - 10 of 23222 matches for " Roberto Amaro Relova "
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Inmunoterapia en la Artritis Reumatoidea
Torres,Virginia; Hernández Cuéllar,María Victoria; Amaro Relova,Roberto; Torres Lima,Ana María;
Revista Cubana de Medicina General Integral , 1999,
Abstract: the immunotherapy in the rheumatoid arthritis includes the use of molecules produced by cells of the immune system or that take part in inflammatory reactions as well as recombinant forms of such molecules. the development of monoclonal antibodies led to the trial of anti t cell therapies without encouraging results. the treatment with anti-tumor necrosis factor alpha monoclonal antibodies is promising at present, as well as the use of recombinant citokines that condition the predominance of type ii helper-t-cells. however, in the future the use of gene therapy could be the most powerful weapon to treat rheumatoid arthritis
Inmunopatogenia de la artritis reumatoidea: Conceptos actuales
Torres Lima,Virginia; Torres Lima,Ana María; Hernández Cuéllar,María Victoria; Amaro Relova,Roberto;
Revista Cubana de Medicina General Integral , 1998,
Abstract: it is reported that rheumatoid arthritis is a systemic autoinmune inflammatory disease whose causes are yet unelear but several factors are supposed to be important in its pathogenesis such as environmental factors and genetic factors (linked to the main histocompatibility complex and to coding genes for the synthesis of inmunoglobulin, t-cell receptors, cytokines and adhesive molecules). when these factors interact, they mediate the articular damage inherent to the disease where inmune response events also participate. additionally, other mechanisms of articular damage by oncogene priming are presented. they regulate both apoptosis and proteolytic enzime priming contributing to pannus formation
Inmunoterapia en la Artritis Reumatoidea
Virginia Torres,María Victoria Hernández Cuéllar,Roberto Amaro Relova,Ana María Torres Lima
Revista Cubana de Medicina General Integral , 1999,
Abstract: La inmunoterapia en la artritis reumatoidea incluye el uso de moléculas producidas por células del sistema inmune, o que participan en reacciones inflamatorias así como formas recombinantes de dichas moléculas. El desarrollo de anticuerpos monoclonales condujo al ensayo de terapias anticélulas T sin resultados alentadores. El tratamiento con anticuerpos monoclonales antifactor de necrosis tumoral alfa resulta prometedor actualmente; así como el uso de citokinas recombinantes que condicionen el predominio de células T cooperadoras tipo 2. Sin embargo, en el futuro el uso de la terapia génica podría ser el arma más poderosa para el tratamiento de la artritis reumatoidea The immunotherapy in the rheumatoid arthritis includes the use of molecules produced by cells of the immune system or that take part in inflammatory reactions as well as recombinant forms of such molecules. The development of monoclonal antibodies led to the trial of anti T cell therapies without encouraging results. The treatment with anti-tumor necrosis factor alpha monoclonal antibodies is promising at present, as well as the use of recombinant citokines that condition the predominance of type II helper-T-cells. However, in the future the use of gene therapy could be the most powerful weapon to treat rheumatoid arthritis
Inmunopatogenia de la artritis reumatoidea: Conceptos actuales
Virginia Torres Lima,Ana María Torres Lima,María Victoria Hernández Cuéllar,Roberto Amaro Relova
Revista Cubana de Medicina General Integral , 1998,
Abstract: Se informa que la artritis reumatoidea es una enfermedad autoinmune inflamatoria y sistémica, cuya causa aún no se ha precisado, pero es de suponer varios factores que son importantes en su patogenia, entre ellos, factores ambientales, genéticos (asociados con el complejo principal de histocompatibilidad y con los genes que codifican la síntesis de inmunoglobulina, del receptor de célula T, citocinas y moléculas de adhseión). Estos factores, al interactuar, median el da o articular propio de la enfermedad, con participación de los sucesos de la respuesta inmune. También se mencionan otros mecanismos de da o articular por activación de oncogenes, que regulan tanto la apoptosis, como la activación de enzimas proteolíticas que contribuyen a la formación del pannus It is reported that rheumatoid arthritis is a systemic autoinmune inflammatory disease whose causes are yet unelear but several factors are supposed to be important in its pathogenesis such as environmental factors and genetic factors (linked to the main histocompatibility complex and to coding genes for the synthesis of inmunoglobulin, T-cell receptors, cytokines and adhesive molecules). When these factors interact, they mediate the articular damage inherent to the disease where inmune response events also participate. Additionally, other mechanisms of articular damage by oncogene priming are presented. They regulate both apoptosis and proteolytic enzime priming contributing to pannus formation
EFEITO DO TRATAMENTO TéRMICO NAS CARACTERíSTICAS FíSICO-QUíMICAS E MICROBIOLóGICAS DA POLPA DE MARACUJá
Alessandra Padovane AMARO,Paulo Roberto Martins BONILHA,Magali MONTEIRO
Alimentos e Nutri??o , 2009,
Abstract: Frutos de maracujá amarelo (Passjflora edulls f. flavicarpa Deg.), material IAC-275, foram processados para a obten o da polpa. A polpa obtida foi pasteurizada durante 30 segundos empregando três faixas de temperatura (69 a 72oC, 73 a 76oC e 77 a 82oC). Foi também obtida polpa fresca (sem pasteurizar). Polpas fresca e pasteurizadas foram comparadas utilizando avalia es físico-químicas e microbiológicas. N o houve diferen a significativa (p > 0,05) nos valores de acidez total, no pH e no ratio das polpas fresca e pasteurizada. A polpa fresca apresentou menor conteúdo de sólidos solúveis totais (p < 0,05) em rela o à polpa pasteurizada e conteúdo de vitamina C praticamente similar, embora tenha havido diferen a significativa (p < 0,05) entre a polpa pasteurizada na faixa de temperatura de 69 a 72oC e as demais. As perdas de vitamina C decorrentes do processamento foram de 5%,4% e 0,6%, quando as faixas de temperatura de 69 a 72°C, 73 a 76°C e 77 a 82°C foram, respectivamente, empregadas. Os resultados da análise microbiológica mostraram que as polpas pasteurizadas apresentaram contagem de bolores e leveduras, de mesófilos aeróbios e de psicrófilos aeróbios significativamente (p < 0,05) menor quando comparadas à polpa fresca, indicando que o tratamento térmico empregado foi adequado.
A comparative analisys of pelvic floor muscle strength in women with stress and urge urinary incontinence
Gameiro, Monica Orsi;Moreira, Eliane Cristina;Ferrari, Renata Spagnoli;Kawano, Paulo Roberto;Padovani, Carlos Roberto;Amaro, Jo?o Luiz;
International braz j urol , 2012, DOI: 10.1590/S1677-55382012000500011
Abstract: aims: to assess pelvic floor muscle (pfm) strength in women with stress urinary incontinence (sui) and urge urinary incontinence (uui). materials and methods: 51 women were prospectively divided into two groups, according to the symptoms as sui (g1 = 22) or uui (g2 = 29). demographic data, such as number of pads/ 24 hours, number of micturations/ 24 hours and nocturia, delay time of urgent void (i.e., the time period for which an urgent void could be voluntarily postponed), number of parity and vaginal deliveries were obtained using a clinical questionnaire. objective urine loss was evaluated by 60-min. pad test, subjective urine stream interruption test (ust) and visual survey of perineal contraction. objective evaluations of pfm were performed in all patients (vaginal manometry). results: median of age, mean number of pads / 24 hours, nocturia and warning time were significantly higher in uui comparing to sui group. during ust, 45.45% in g1 and 3.44%, in g2, were able to interrupt the urine stream (p < 0.001). the 60-min. pad test was significantly higher in g2 compared to g1 women (2.7 ± 2.4 vs 1.5 ± 1.9 respectively, p = 0.049). objective evaluation of pfm strength was significantly higher in the sui than in the uui patients. no statistical difference was observed regarding other studied parameters. conclusion: pelvic floor muscle weakness was significantly higher in women with uui when compared to sui.
AISLAMIENTO DE CORONAVIRUS BOVINO POR PRIMERA VEZ EN CUBA
Betancourt,A; Rodríguez,Edisleidy; Relova,Damarys; Barrera,Maritza;
Revista de Salud Animal , 2007,
Abstract: faecal samples were tested for bovine coronavirus by means of agglutination of hamster erythrocytes and hemagglutination inhibition. isolation of bovine coronavirus was carried out in monolayers of primary culture of calf kidney, using faecal samples from dairy cows with clinical signs similar to winter dysentery. when isolated, they were submitted to seroneutralization with anti-bovine coronavirus serum. these isolates were confirmed to be positive, once being neutralized.
CLONAJE BIOLóGICO DE UN AISLADO DE CORONAVIRUS BOVINO
Betancourt,A; Rodríguez,Edisleidy; Relova,Damarys; Barrera,Maritza;
Revista de Salud Animal , 2008,
Abstract: in order to obtain a biologically cloned bovine coronavirus isolate, the isolate vb73/04 was adapted to multiplication in mdbk cell line. this isolate induced the formation of plaques, which were homogeneous after biological cloning. the viral population obtained was tested for bovine coronavirus by rt-pcr assay and seroneutralization.
Caracterización de la situación clínico-epizootiológica de la mastitis bovina en vacas primerizas Holstein de una lechería especializada
Relova Vento, Damarys,Armenteros Amaya, Mabelin,Capdevila Varela, José Z.
REDVET , 2008,
Abstract: La mastitis bovina sigue siendo la enfermedad más común y costosa delganado lechero. El objetivo de este trabajo, consistió en realizar una caracterización de la situación clínico-epizootiológica de la mastitis bovina en vacas primerizas holstein de una lechería especializada. Para ello se realizó una evaluación del estado clínico y microbiológico de la ubre a 20 vacas de primer parto, mediante la prueba de california (CMT), el examen clínico de la ubre y el aislamiento bacteriológico. De los 80 cuartos evaluados el 26% se encontraban afectados por mastitis clínica, el 77% por mastitis subclínica y a la palpación postorde o el 40% se encontrabanafectados por mastitis crónica. Los microorganismos patógenos productores de mastitis aislados fueron: Corynebacterium bovis, Streptococcus agalactiae y Staphylococcus aureus, con una prevalencia de 27.5%, 12.5% y 1.2% respectivamente. El patrón de sensibilidad, observado a partir de los antibiogramas realizados a los dos microorganismos que estaban circulando con mayor prevalencia fue similar e indicó una mayor sensibilidad a la Gentamicina, Enrofloxacina y Bacitracina. Los casos de mastitis identificados fueron fundamentalmente de origen infeccioso y estuvo influenciado de forma directa, por la inadecuada rutina de orde o y fallas en el tratamiento de de casos clínicos y en la terapia de vacas seca,que conllevó a que el índice de salubridad fuese de un 10 %. Ello demostró la necesidad de la reactivación de un programa de control de mastitis en la unidad.
Comparison of pelvic floor muscle strength evaluations in nulliparous and primiparous women: a prospective study
Gameiro, M?nica Orsi;Sousa, Vanessa Oliveira;Gameiro, Luiz Felipe;Muchailh, Rosana Carneiro;Padovani, Carlos Roberto;Amaro, Jo?o Luiz;
Clinics , 2011, DOI: 10.1590/S1807-59322011000800014
Abstract: objective: this study aimed to compare the pelvic floor muscle strength of nulliparous and primiparous women. methods: a total of 100 women were prospectively distributed into two groups: group 1 (g1) (n = 50) included healthy nulliparous women, and group 2 (g2) (n = 50) included healthy primiparous women. pelvic floor muscle strength was subjectively evaluated using transvaginal digital palpation. pelvic floor muscle strength was objectively assessed using a portable perineometer. all of the parameters were evaluated simultaneously in g1 and were evaluated in g2 during the 20th and 36th weeks of pregnancy and 45 days after delivery. results: in g2, 14 women were excluded because they left the study before the follow-up evaluation. the median age was 23 years in g1 and 22 years in g2; there was no significant difference between the groups. the average body mass index was 21.7 kg/m2 in g1 and 25.0 kg/m2 in g2; there was a significant difference between the groups (p = 0.0004). in g2, transvaginal digital palpation evaluation showed significant impairments of pelvic floor muscle strength at the 36th week of pregnancy (p = 0.0006) and 45 days after vaginal delivery (p = 0.0001) compared to g1. objective evaluations of pelvic floor muscle strength in g2 revealed a significant decrease 45 days after vaginal delivery compared to nulliparous patients. conclusion: pregnancy and vaginal delivery may cause weakness of the pelvic floor muscles.
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