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Search Results: 1 - 10 of 27354 matches for " Ricardo Rocha "
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The Significance of the ProtDeform Score for Structure Prediction and Alignment
Jairo Rocha, Ricardo Alberich
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0020889
Abstract: Background When a researcher uses a program to align two proteins and gets a score, one of her main concerns is how often the program gives a similar score to pairs that are or are not in the same fold. This issue was analysed in detail recently for the program TM-align with its associated TM-score. It was shown that because the TM-score is length independent, it allows a P-value and a hit probability to be defined depending only on the score. Also, it was found that the TM-scores of gapless alignments closely follow an Extreme Value Distribution (EVD). The program ProtDeform for structural protein alignment was developed recently and is characterised by the ability to propose different transformations of different protein regions. Our goal is to analyse its associated score to allow a researcher to have objective reasons to prefer one aligner over another, and carry out a better interpretation of the output. Results The study on the ProtDeform score reveals that it is length independent in a wider score range than TM-scores and that PD-scores of gapless (random) alignments also approximately follow an EVD. On the CASP8 predictions, PD-scores and TM-scores, with respect to native structures, are highly correlated (0.95), and show that around a fifth of the predictions have a quality as low as 99.5% of the random scores. Using the Gold Standard benchmark, ProtDeform has lower probabilities of error than TM-align both at a similar speed. The analysis is extended to homology discrimination showing that, again, ProtDeform offers higher hit probabilities than TM-align. Finally, we suggest using three different P-values according to the three different contexts: Gapless alignments, optimised alignments for fold discrimination and that for superfamily discrimination. In conclusion, PD-scores are at the very least as valuable for prediction scoring as TM-scores, and on the protein classification problem, even more reliable.
Estudo comparativo de eco-Doppler com arteriografia na avalia??o da doen?a oclusiva aorto-ilíaca
Moreira, Ricardo Cesar Rocha;
Jornal Vascular Brasileiro , 2009, DOI: 10.1590/S1677-54492009000100002
Abstract: background: contrast arteriography (ca) has been the traditional method of evaluation of patients with suspected aortoiliac occlusive disease (aiod). recently, less invasive methods, such as doppler ultrasonography, have been used for the same purpose. objective: the present study prospectively compares doppler ultrasonography with ca and direct arterial manometry (dam) in the preoperative evaluation of patients with suspected aiod. methods: a total of 125 patients admitted for treatment of arterial occlusive disease of the lower extremities underwent doppler ultrasonography and ca, comparatively evaluating 552 aortic, common iliac e external iliac segments. the lesions found were classified into five categories: 1) normal and mild stenosis (0-19%); 2) moderate stenosis (20-49%); 3) significant stenosis (50-79%); 4) critical stenosis (80-99%); and 5) total occlusion. dam was used in 19 segments of 15 patients to classify borderline lesions. validity indexes (sensitivity, specificity, positive predictive value, negative predictive value and overall accuracy) were calculated to distinguish hemodynamically significant from non-significant stenosis and to discriminate critical stenosis from total occlusions. the gold standard was ca, supplemented by dam. correlation coefficients (kappa statistics) between arteriography and doppler ultrasonography were also calculated for the whole sample of aortoiliac segments. results: clinically relevant lesions (stenoses between 50-99% and total occlusions) were observed on doppler ultrasonography in 163 segments (29.5%) and on ca in 158 segments (28.6%). doppler ultrasonography showed high validity indexes to distinguish hemodynamically significant from non-significant lesions (overall accuracy = 92%; kappa = 0.81) and an overall accuracy of 86% (kappa = 0.73) to distinguish critical stenosis from total occlusion. optimal correlation coefficients between the results of doppler ultrasonography and ca were observed for all aortoiliac
Turismo estudiantil masivo en Bariloche - Argentina: Estrategias de recreación en las discotecas
Rocha,Norberto; Surdo,Ricardo;
Estudios y perspectivas en turismo , 2005,
Abstract: mass student tourism in bariloche (mst) argentina. recreational strategies of the discos. discotheques have a remarkable symbolic importance in teenage culture, contributing to lessen physical student tourist’s recovery during their trip in bariloche. discotheques induced and controlled behaviors, emotions and sensations by means of their infrastructure and personnel. they created `freedom′ imaginaries, group identifications, student’s experience `exclusiveness′ in `their′ night in `their′ disco in `their′ trip. alcohol is a landmark of night culture and student’s trip. `undesirable′ behaviors were smallest.
A arquitetura moderna diante da esfinge ou a nova monumentalidade: uma análise do Monumento Nacional aos Mortos na Segunda Guerra Mundial, Rio de Janeiro
Rocha, Ricardo de Souza;
Anais do Museu Paulista: História e Cultura Material , 2007, DOI: 10.1590/S0101-47142007000200016
Abstract: the purpose of this paper is to analyze the national memorial to the world war ii dead (1956-60), a monument designed by marcos konder netto and hélio ribas marinho, and located in flamengo park, rio de janeiro. we start by commenting on the debates that were going on within the modernist movement about the need for a new monumentality. then, we examine the memorial against the urban landscape of rio de janeiro and its specific architectural language. finally, we make an effort to explain the apparent paradox found in modern monuments.
A arquitetura moderna diante da esfinge ou a nova monumentalidade - uma análise do Monumento Nacional aos Mortos na Segunda Guerra Mundial, Rio de Janeiro
Ricardo de Souza Rocha
Anais do Museu Paulista: História e Cultura Material , 2007,
Abstract: The purpose of this paper is to analyze the National Memorial to the World War II Dead (1956-60), a monument designed by Marcos Konder Netto and Hélio Ribas Marinho, and located in Flamengo Park, Rio de Janeiro. We start by commenting on the debates that were going on within the Modernist movement about the need for a new monumentality. Then, we examine the memorial against the urban landscape of Rio de Janeiro and its specific architectural language. Finally, we make an effort to explain the apparent paradox found in modern monuments.
Turismo estudiantil masivo en Bariloche - Argentina: Estrategias de recreación en las discotecas
Norberto Rocha,Ricardo Surdo
Estudios y perspectivas en turismo , 2005,
Abstract: En este trabajo se analiza el papel de la recreación organizada en las discotecas en el turismo estudiantil masivo en Bariloche, Argentina. Las discotecas tienen gran importancia simbólica en la cultura adolescente, contribuyendo a la disminución de la recuperación física de los turistas estudiantiles durante su estadía en Bariloche. Las discotecas promovieron y controlaron conductas, emociones y sensaciones mediante su equipamiento y personal. Crearon imaginarios de "libertad", identificaciones grupales, "exclusividad" de la experiencia de los futuros egresados en "su" noche en "su" discoteca en "su" viaje. El alcohol es emblemático de la cultura nochera y el viaje de egresados. Las conductas "indeseables" fueron minoritarias. Mass Student Tourism in Bariloche (MST) Argentina. Recreational Strategies of The Discos. Discotheques have a remarkable symbolic importance in teenage culture, contributing to lessen physical student tourist’s recovery during their trip in Bariloche. Discotheques induced and controlled behaviors, emotions and sensations by means of their infrastructure and personnel. They created `freedom′ imaginaries, group identifications, student’s experience `exclusiveness′ in `their′ night in `their′ disco in `their′ trip. Alcohol is a landmark of night culture and student’s trip. `Undesirable′ behaviors were smallest.
Trauma vascular Review of the book "Vascular trauma"
Ricardo C. Rocha Moreira
Jornal Vascular Brasileiro , 2008, DOI: 10.1590/s1677-54492008000200018
Abstract:
Por que os cirurgi es vasculares brasileiros publicam t o pouco? Why do Brazilian vascular surgeons publish so little?
Ricardo C. Rocha Moreira
Jornal Vascular Brasileiro , 2008, DOI: 10.1590/s1677-54492008000400001
Abstract:
A reanálise dos clíticos me e te em estruturas de redobro pronominal no dialeto mineiro
Ricardo Machado Rocha
Caligrama : Revista de Estudos Romanicos , 2011,
Abstract: Resumo: Neste artigo, analisamos a ocorrência das formas pronominais me e te em estruturas de redobro. Argumentamos que, em alguns falares mineiros, essas formas est o sendo reanalisadas como prefixos de concordancia para os tra os de pessoa [+falante] e [+destinatário]. O trabalho se desenvolve dentro da abordagem minimalista. Lan amos m o também de alguns conceitos de gramaticaliza o. Palavras-chave: Pronomes pessoais; clíticos redobros; concordancia; reanálise; gramaticaliza o. Abstract: This study examines the occurrence of the pronoun forms me and te in clitic doubling structures. We argue that in some nonstandard Brazilian Portuguese dialects from the state of Minas Gerais, these forms are being reanalyzed as prefixes of agreement for the person features [+speaker] and [+addressee]. The analysis is developed within the minimalist approach. We used also some concepts of grammaticalization. Keywords: Personal pronouns; clitic doubling; agreement; reanalysis; grammaticalization.
On Combining Linear-Based Strategies for Tabled Evaluation of Logic Programs
Miguel Areias,Ricardo Rocha
Computer Science , 2011, DOI: 10.1017/S147106841100024X
Abstract: Tabled evaluation is a recognized and powerful technique that overcomes some limitations of traditional Prolog systems in dealing with recursion and redundant sub-computations. We can distinguish two main categories of tabling mechanisms: suspension-based tabling and linear tabling. While suspension-based mechanisms are considered to obtain better results in general, they have more memory space requirements and are more complex and harder to implement than linear tabling mechanisms. Arguably, the SLDT and DRA strategies are the two most successful extensions to standard linear tabled evaluation. In this work, we propose a new strategy, named DRS, and we present a framework, on top of the Yap system, that supports the combination of all these three strategies. Our implementation shares the underlying execution environment and most of the data structures used to implement tabling in Yap. We thus argue that all these common features allows us to make a first and fair comparison between these different linear tabling strategies and, therefore, better understand the advantages and weaknesses of each, when used solely or combined with the others.
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