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Search Results: 1 - 10 of 6073 matches for " Reza Khatami "
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Implications of Classification of Methodological Decisions in Flooding Analysis from Hurricane Katrina
Reza Khatami,Giorgos Mountrakis
Remote Sensing , 2012, DOI: 10.3390/rs4123877
Abstract: Recent climatic patterns indicate that extreme weather events will increase in frequency and magnitude. Remote sensing offers unique advantages for large-scale monitoring. In this research, Landsat 5 remotely sensed imagery was used to assess flooding caused by Hurricane Katrina, one of the worst natural disasters in the US over the past decades. The objective of our work is to assess whether decisions associated with the classification process, such as location of reference data and algorithm choice, affected flooding results and subsequent analysis using census data. Maximum Likelihood (ML) and Back Propagation Neural Network (NN) were the tested algorithms, the former reflecting a simple and popular classifier, and the latter an advanced but complex method. Flooding estimations were almost identical within the reference sample area, 124.4 km2 for the ML classifier and 123.7 km2 for the NN classifier. However, large discrepancies were found outside the reference sample area with the ML predicting 462.5 km2 and the NN identifying 797.2 km2 as flooded, almost twice the amount. Further investigation took place to evaluate the influence of the classification method to a social study, namely the racial characteristics of flooded areas. Using Census 2000 data, our study area was segmented in census tracts. Results indicated a strong positive correlation between concentration of African Americans and proportional residential flooding. Pairwise T-Tests also verified that flooding among different African American concentrations was statistically different. There were no significant differences between the ML and NN methods in the results interpretation, which is mostly attributed to the significant geographic overlap between reference sample area and the examined census tracts. This study suggests that emergency responders should exercise significant caution in their decision making when using classification products from undersampled geographic areas in terms of classification reference data.
Atherosclerosis After Kidney Transplantation: Changes of Intima-Media Thickness of Carotids During Early Posttransplant Period
Mohsen Nafar,Farideh Khatami,Babak Kardavani,Reza Farjad
Urology Journal , 2007,
Abstract: Introduction: The aim of this study was to evaluate atherosclerotic changes in the carotid artery following kidney transplantation. Materials and Methods: Twenty-six nonsmoker kidney allograft recipients who did not have cardiovascular disease or diabetes mellitus were enrolled in the study. The carotid intima-media thickness (IMT) was measured at 12 points using B-mode ultrasonography. The mean of the measured values was considered as the patient’s IMT. We followed the patients and changes in the carotid IMT were evaluated every 2 months up to the 6th posttransplant month. Results: The mean age of the patients at transplantation was 41.5 ± 11.1 years. The mean baseline IMT was 0.84 ± 0.22 mm. During the follow-up period it reached 0.85 ± 0.22 mm, 0.87 ± 0.23 mm (P = .01), and 0.88 ± 0.24 mm (P = .002) after 2, 4, and 6 months, respectively. The IMT measures significantly correlated with the age and body mass index. Using the IMT cutoff points of 0.75 mm for stroke and 0.82 mm for MI, we found that 57.7% and 68% of the patients were at the risk of stroke at baseline and 6 months after transplantation (P < .001). Also, 46.2 % of the patients were at the risk of MI at baseline that rose to 53.8% at the end of the study (P < .001). Conclusion: Atherosclerosis is an early event after kidney transplantation even in asymptomatic patients and those without major risk factors such as cardiovascular disease, diabetes mellitus, and smoking. Early diagnosis and treatment of atherosclerosis is of utmost importance
Molecular Characterization of Cosenza Mutation among Patients with Glucose-6-Phosphate Dehydrogenase Deficiency in Khuzestan Province, Southwest Iran
Seyed Reza Kazemi Nezhad,Fatemeh Fahmi,Saeid Reza Khatami,Mohsen Musaviun
Iranian Journal of Medical Sciences , 2011,
Abstract: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common hereditary enzymatic disorders in human, increases the vulnerability of erythrocytes to oxidative stress. It is also characterized by remarkable molecular and biochemical heterogeneity. According to previous investigations, G6PD Cosenza (G1376C) is a common G6PD mutation in some parts of Iran. Therefore in the present study we have characterized Cosenza mutation among G6PD deficient individuals in Khuzestan province. In order to identify G6PD Cosenza, we analyzed the G6PD gene in 64 samples out of 231 deficient individuals who had not G6PD Mediterranean mutation, using PCR- restriction fragment length polymorphism (RFLP) method. G6PD Cosenza mutation was found in 6 males of 231 samples, resulting in the relative rate of 2.6% and allele frequency of 0.023 among Khuzestanian G6PD deficient subjects. A comparison of these results with previous findings in some parts of Iran suggests that G6PD Cosenza is a common mutation in Khuzestanian G6PD deficient individuals
Ehlers-Danlos Syndrome Type VI in a 17-Year-Old Iranian Boy with Severe Muscular Weakness – A Diagnostic Challenge?
Ariana Kariminejad,Bita Bozorgmehr,Ali-Reza Khatami,Mohamad-Hasan Kariminejad
Iranian Journal of Pediatrics , 2010,
Abstract: Background:The Ehlers-Danlos syndrome type VI (EDSVI) is an autosomal recessive connective tissue disease which is characterized by severe hypotonia at birth, progressive kyphoscoliosis, skin hyperelasticity and fragility, joint hypermobility and (sub-)luxations, microcornea, rupture of arteries and the eye globe, and osteopenia. The enzyme collagen lysyl hydroxylase (LH1) is deficient in these patients due to mutations in the PLOD1 gene. Case Presentation:We report a 17-year-old boy, born to related parents, with severe kyphoscoliosis, scar formation, joint hypermobility and multiple dislocations, muscular weakness, rupture of an ocular globe, and a history of severe infantile hypotonia. EDS VI was suspected clinically and confirmed by an elevated ratio of urinary total lysyl pyridinoline to hydroxylysyl pyridinoline, abnormal electrophoretic mobility of the α-collagen chains, and mutation analysis. Conclusion:Because of the high rate of consanguineous marriages in Iran and, as a consequence thereof, an increased rate of autosomal recessive disorders, we urge physicians to consider EDS VI in the differential diagnosis of severe infantile hypotonia and muscular weakness, a disorder which can easily be confirmed by the analysis of urinary pyridinolines that is highly specific, sensitive, robust, fast, non-invasive, and inexpensive.
A Panel of Cancer Testis Antigens and Clinical Risk Factors to Predict Metastasis in Colorectal Cancer
Ramyar Molania,Frouzandeh Mahjoubi,Rezvan Mirzaei,Saeed-Reza Khatami,Bahar Mahjoubi
Journal of Biomarkers , 2014, DOI: 10.1155/2014/272683
Abstract: Colorectal cancer (CRC) is the third common carcinoma with a high rate of mortality worldwide and several studies have investigated some molecular and clinicopathological markers for diagnosis and prognosis of its malignant phenotypes. The aim of this study is to evaluate expression frequency of PAGE4, SCP-1, and SPANXA/D cancer testis antigen (CTA) genes as well as some clinical risk markers to predict liver metastasis of colorectal cancer patients. The expression frequency of PAGE4, SCP-1, and SPANXA/D cancer/testis antigen (CTA) genes was obtained using reverse transcription polymerase chain reaction (RT-PCR) assay in 90 colorectal tumor samples including both negative and positive liver metastasis tumors. Statistical analysis was performed to assess the association of three studied genes and clinical risk factors with CRC liver metastasis. The frequency of PAGE4 and SCP-1 genes expression was significantly higher in the primary tumours with liver metastasis when statistically compared with primary tumors with no liver metastasis ( ). Among all clinical risk factors studied, the lymph node metastasis and the depth of invasion were statistically correlated with liver metastasis of CRC patients. In addition, using multiple logistic regression, we constructed a model based on PAGE4 and lymph node metastasis to predict liver metastasis of CRC. 1. Introduction Colorectal cancer (CRC) is the third common cancer and the fourth cause of mortality throughout the world [1]. Accumulating evidence shows that CRC can metastasise to many organs and CRC patients die mainly from metastatic disease. Liver is the preferential target of the CRC metastasis [2]. Nearly 10–25% of CRC patients on diagnosis have liver metastases. However, 20–50% of CRC patients with no detectable metastasis at the time of resection of the primary tumor will develop liver metastases later on [3–5]. Liver resection in CRC patients with liver metastasis remains the best treatment option and it is associated with a survival rate and a 20–25% of long-term survivors [6]. However, without treatment, the median overall survival is approximately 9 months after the recognition of liver metastases [6]. To boost the survival rate of CRC patients, selection of patients at high risk for liver metastasis is crucial. Two of the most important conventional pathological risk factors for diagnosis of colorectal liver metastasis (CLM) are lymph node metastasis and lymphatic invasion [7]. Molecular studies have shown that there are some useful markers for predicting CLM. Several tumor-associated antigens (TAAs)
Truncated MTA-1: A Pitfall in ELISA-Based Immunoassay of HTLV-1 Infection
Mohammad Reza Abbaszadegan,Narges Jafarzadeh,Mojtaba Sankian,AbdolReza Varasteh,Mahmoud Mahmoudi,Majid Sadeghizadeh,Fatemeh Khatami,Neema Mehramiz
Journal of Biomedicine and Biotechnology , 2008, DOI: 10.1155/2008/846371
Abstract: HTLV-1 causes adult T-cell leukemia (ATL) and HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). Recombinant envelope glycoprotein is used in production of diagnostic enzyme-linked immunosorbent assay (ELISA) kit. There are some reports that a significant percentage of Iranian HTLV-1 infected patients showed no seroreactivity with MTA-1 peptide, while HTLV-1 had been confirmed by PCR detection methods or ELISA kits containing a cocktail of HTLV-1 specific peptides. This report describes experiments designed to determine whether some discrepancies between ELISA and PCR results could be due to truncation of immunodominant epitopes using immunoassay method. We have cloned the MTA-1 epitope of env gene from HTLV-1 in NotI/NdeI sites of pET22b(
Iranian Journal of Child Neurology , 2012,
Evaluation of diagnostic test accuracy studies
Alireza Khatami
Dermatology and Cosmetic , 2011,
Abstract: "nIn the recent years, advances in different fields of technology have been resulted in a dramatic increase in the diagnostic methods and tests in different branches of clinical medicine with a consequent increase in the number of scientific publications related to the application of those tests and methods in the diagnosis or prevention of diseases. Dermatology is not an exception. Since, evidence-based medicine emphasizes on the appropriate use of the current best clinical research evidence in the diagnosis or treatment of each individual patient acknowledging his/her values, the capability of dermatologists in appraisal and application of the publications, which reports the results of diagnostic test accuracy studies cannot be ignored. In this article, after a brief review on basic issues in diagnostic test accuracy studies, principles of critical appraisal of these studies, from an evidence-based viewpoint, will be discussed. General strategies for evaluation of validity, applicability and quality assessment of a diagnostic test study will be provided.
A Note On Gorenstein Injective Dimension
Leila Khatami
Mathematics , 2006,
Abstract: The Chouinard's formula for injective dimension is extended to the Gorenstein injective dimension.
The smallest part of the generic partition of the nilpotent commutator of a nilpotent matrix
Leila Khatami
Mathematics , 2013,
Abstract: Let $k$ be an infinite field. Fix a Jordan nilpotent $n$ by $n$ matrix $B = J_P$ with entries in $k$ and associated Jordan type $P$. Let $Q(P)$ be the Jordan type of a generic nilpotent matrix commuting with $B$. In this paper, we use the combinatorics of a poset associated to the partition $P$, to give an explicit formula for the smallest part of $Q(P)$, which is independent of the characteristic of $k$. This, in particular, leads to a complete description of $Q(P)$ when it has at most three parts.
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