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Search Results: 1 - 10 of 52656 matches for " Ravindra Y Patil "
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Antihistaminic activity of Clitoria ternatea L. roots
Dnyaneshwar J Taur,Ravindra Y Patil
Journal of Basic and Clinical Pharmacy , 2011,
Abstract: Clonidine, a α2 adrenoreceptor agonist induces dose dependent catalepsy in mice, which was inhibited by histamine H1 receptor antagonists but not by H2 receptor antagonist. Clonidine releases histamine from mast cells which is responsible for different asthmatic conditions. Clitoria ternatea L. (Family: Fabaceae) is a perimial twing herb. The roots have anti-inflammatory properties and are useful in severe bronchitis, asthma. In present study ethanol extract of Clitoria ternatea root (ECTR) at doses 100, 125 and 150 mg/kg i.p were evaluated for antihistaminic activity using clonidine and haloperidol induced catalepsy in mice. Finding of investigation showed that chlorpheniramine maleate (CPM) and ECTR inhibit clonidine induced catalepsy significantly P < 0.001 when compare to control group, while CPM and ECTR fail to inhibit haloperidol induced catalepsy. Present study concludes that ECTR possessesantihistaminic activity.
Offline Handwritten Signatures Classification Using Wavelet Packets and Level Similarity Based Scoring
Poornima G Patil,Ravindra S Hegadi
International Journal of Engineering and Technology , 2013,
Abstract: Offline Signature Classification has been extensively studied for many years. The challenge in this area is the correct classification of skilled forgeries which are the result of deliberate practice toimitate the signatures of any person. In this paper the preprocessed images of genuine handwritten signatures are subjected to analysis by Wavelet Packets. A regular wavelet like db4 has been used to dothe decomposition upto four levels. The resulting decomposed signal is further subjected to wavelet multiscale principal component analysis done for ten levels. The principal components are chosenaccording to the kais rule. The selected principal components consist of details at ten different levels and one approximation for each signature image. For a given test signature image the principal components are extracted in the same way and the principal components at each level are compared against the mean principal components of the genuine signatures at the corresponding level and the difference is within the permissible range, then a score is assigned. The collective score obtained due to all levels is used to classify the signature as genuine or forgery. The proposed system has a FAR of 12% and a FRR of 8%.
Using Layer Recurrent Neural Network to Generate Pseudo Random Number Sequences
Veena Desai,Ravindra Patil,Dandina Rao
International Journal of Computer Science Issues , 2012,
Abstract: Pseudo Random Numbers (PRNs) are required for many cryptographic applications. This paper proposes a new method for generating PRNs using Layer Recurrent Neural Network (LRNN). The proposed technique generates PRNs from the weight matrix obtained from the layer weights of the LRNN. The LRNN random number generator (RNG) uses a short keyword as a seed and generates a long sequence as a pseudo PRN sequence. The number of bits generated in the PRN sequence depends on the number of neurons in the input layer of the LRNN. The generated PRN sequence changes, with a change in the training function of the LRNN .The sequences generated are a function of the keyword, initial state of network and the training function. In our implementation the PRN sequences have been generated using 3 training functions: 1)Scaled Gradient Descent 2)Levenberg-Marquartz (TRAINLM) and 3) TRAINBGF. The generated sequences are tested for randomness using ENT and NIST test suites. The ENT test can be applied for sequences of small size. NIST has 16 tests to test random numbers. The LRNN generated PRNs pass in 11 tests, show no observations for 4 tests, and fail in 1 test when subjected to NIST .This paper presents the test results for random number sequence ranging from 25 bits to 1000 bits, generated using LRNN.
Microwave Induced Synthesis and Antimicrobial Activities of Some Derivatives of 3, 5-Diaryl-2-pyrazoline-1-carbaldehyde
Ravindra Kumar,Y. K. Srivastava
Journal of Chemistry , 2010, DOI: 10.1155/2010/160570
A validated chiral LC method for the enantiomeric separation of repaglinide on immobilized amylose based stationary phase
Patil, Kiran;Rane, Vipul;Yeole, Ravindra;Shinde, Devanand;
Journal of the Brazilian Chemical Society , 2012, DOI: 10.1590/S0103-50532012000600008
Abstract: a simple, rapid, isocratic, normal phase chiral hplc method was developed and validated for the enantiomeric separation of repaglinide, (s)-(+)-2-ethoxy-4-n [1-(2-piperidinophenyl)-3-methyl-1-butyl] aminocarbonylmethyl] benzoic acid, an antidiabetic drug substance. the enantiomers of repaglinide were resolved on a chiralpak ia (immobilized amylose based stationary phase) column using a mobile phase consisting of n-hexane:ethanol:trifluoroacetic acid (80:20:0.2, v/v/v) at a flow rate of 1.0 ml min-1. the resolution between both enantiomers was greater than 2 in the optimized method. the developed method was extensively validated and proved to be robust, enantioselective, accurate, precise, and suitable for quantitative determination of (r)-enantiomer in bulk drug substance and product.
Comparative Study Of Gandhian Philosophy And Environmental Concerns With Special Reference To Modern Management Streams
Ashok Bhise , Saptarshi,Praveen , Jaybhaye Ravindra,Pandurang Patil
Golden Research Thoughts , 2013, DOI: 10.9780/22315063
Abstract: Gandhian management is based on Gandhian philosophy of love, truth and nonviolence. His philosophy is integrated with his principles and practices that add to new dimension to the fields of management. It is essential to understand his qualities of management style. It is for the betterment of the country and business to interpret and adopt these principles correctly. In the first part we shall study various Gandhian principle of management. In the Second part efforts are made to compare these principles with modern management streams.In the age of globalization, if anybody talks about ethical management and code of conduct, then it is not so easy to implement the same. This is because ethical management and value-based management requires clear-cut base of ethics and values. Even today business gurus are talking about Gandhiji's principles, to consider Gandhiji as role model of nation. But application of Gandhiji's principles in today's management is a matter of discussion or debate.
Additional circular intercostal space created by bifurcation of the left 3rd rib and its costal cartilage: a case report
Kumar Naveen,Guru Anitha,Patil Jyothsna,Ravindra Swamy
Journal of Medical Case Reports , 2013, DOI: 10.1186/1752-1947-7-6
Abstract: Introduction In the thorax there are normally 11 pairs of intercostal spaces: the spaces between adjacent ribs. The intercostal spaces contain intercostal muscles, intercostal nerves and vessels. Case presentation During a routine dissection for undergraduate medical students, we observed a variation involving the left 3rd rib and 3rd costal cartilage in the cadaver of a man of Indian ethnicity aged about 65 years. The left 3rd rib and its costal cartilage were bifurcated at their costochondral junction enclosing a small circular additional intercostal space. Muscle tissue covered by deep fascia was present in this circular intercostal space. The muscle in the circular intercostal space received its nerve supply from a branch of the 2nd intercostal nerve. Conclusions Knowledge of such variations is helpful to surgeons operating on the anterior thoracic wall involving ribs and intercostal spaces. Knowing the possibility of the presence of an additional space between normal intercostal spaces can guide a surgeon through to a successful surgery.
Patil Y. R.
International Journal of Research in Ayurveda and Pharmacy , 2012,
Abstract: Guduchi is being used as a rejuvenating herb in Ayurveda and other system of medicine since many decades. Guduchi is prescribed as a monoherbal as well as polyherbal formulation. The herb has free radical scavenging properties against reactive oxygen and nitrogen. Due to its Rasayana (free radical scavenging property) it was decided to evaluate efficacy of its juice in growth of children by comparing with standard growth charts developed by National centre for health statistics. 30 Children of age group 6 to 8 years were recruited in the trial. Children were assessed and evaluated on the basis of objective and subjective parameters at interval of 15 days for 3 months. Mean weight of children at baseline of study was 19.99 ± 1.59 kg and was increased moderately to 20.64 ± 1.57 kg (at 12th wk). Mean score of skin luster was 0.43 ± 0.5 and it was increased significantly to 1.17 ± 0.37. Diet intake of these children at baseline was 0.467 ± 0.51 and in was increased significantly to 1.63 ± 0.48. These findings suggest that juice of Tinospora cordifolia is an effective, safe, and herbal formulation for the children growth.
Pineapple Juice as a Natural Catalyst: An Excellent Catalyst for Biginelli Reaction  [PDF]
Suresh Patil, Swati D. Jadhav, Sanjeevani Y. Mane
International Journal of Organic Chemistry (IJOC) , 2011, DOI: 10.4236/ijoc.2011.13019
Abstract: An efficient and greener synthesis of a series of dihydropyrimidinone (DHPMs) derivatives were accomplished via three-component one-pot cyclocondensation between substituted aryl aldehydes, diketone/ke- toester and urea. This solvent free approach is totally nonpolluting having several advantages such as shorter reaction time, mild reaction conditions, simple workup and reduced environmental impact.
Melatonin in pathogenesis and therapy of cancer
Ravindra T,Lakshmi N,Ahuja Y
Indian Journal of Medical Sciences , 2006,
Abstract: Melatonin is a neuroendocrine hormone secreted by the pineal gland to transduce the body′s circadian rhythms. An internal 24 hour time keeping system (biological clock) regulated by melatonin, controls the sleep-wake cycle. Melatonin production is a highly conserved evolutionary phenomenon. The indole hormone is synthesized in the pinealocytes derived from photoreceptors. Altered patterns and/or levels of melatonin secretion have been reported to coincide with sleep disorders, jetlag, depression, stress, reproductive activities, some forms of cancer and immunological disorders. Lately, the physiological and pathological role of melatonin has become a priority area of investigation, particularly in breast cancer, melanoma, colon cancer, lung cancer and leukemia. According to the ′melatonin hypothesis′ of cancer, the exposure to light at night (LAN) and anthropogenic electric and magnetic fields (EMFs) is related to the increased incidence of breast cancer and childhood leukaemia via melatonin disruption. Melatonin′s hypothermic, antioxidant and free radical scavenging properties, attribute it to an immunomodulator and an oncostatic agent as well. Many clinical studies have envisaged the potential therapeutic role of melatonin in various pathophysiological disorders, particularly cancer. A substantial reduction in risk of death and low adverse effects were reported from various randomized controlled trials of melatonin treatment in cancer patients. This review summarizes the physiological significance of melatonin and its potential role in cancer therapy. Furthermore, the article focuses on melatonin hypothesis to represent the cause-effect relationship of the three aspects: EMF, LAN and cancer.
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