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Search Results: 1 - 10 of 83705 matches for " Raquel da Silva Teixeira "
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Mushroom tyrosinase inhibitory activity and major fatty acid constituents of Amazonian native flora oils
Raquel da Silva Teixeira,Paula Rafaela Rocha,Hudson Caetano Polonini,Marcos Ant?nio Fernandes Brand?o
Brazilian Journal of Pharmaceutical Sciences , 2012, DOI: 10.1590/s1984-82502012000300006
Abstract: In order to treat hyperpigmentation-related problems, there has been a global trend in developing cosmetics claiming to have skin-whitening properties, which act by inhibiting melanin biosynthesis. The objective of this work was to evaluate the in vitro mushroom tyrosinase inhibitory activity of five Amazonian native flora oils, and so to verify the possibility of their incorporation into cosmetic products. In addition, the fatty acid composition of the essential oils was determined by gas chromatography-flame ionisation detection in order to determine the main components of these oils. The tyrosinase inhibitory activity of the tested oils was found to be in the following order: a aí (IA50 = 66.08 μg mL-1) > tucum > patauá > pracaxi > castanha do Brasil. This study suggests that a aí oil has great potential in the treatment of hyperpigmentation and other related disorders, due to its considerable tyrosinase inhibitory activity. Com o intuito de se tratar problemas dermatológicos de hiperpigmenta o, há uma tendência mundial no desenvolvimento de cosméticos que possuam propriedades despigmentantes, os quais agem inibindo a biossíntese de melanina. O objetivo deste trabalho foi avaliar in vitro a atividade de inibi o da tirosinase de cogumelo de cinco óleos de plantas nativas da Amaz nia e, desta forma, verificar a possibilidade de sua incorpora o em produtos cosméticos. Ainda, a composi o de ácidos graxos dos óleos foi determinada por cromatografia gasosa com detec o por ioniza o de chama, no intuito de determinar os principais componentes destes óleos. A atividade de inibi o da tirosinase dos óleos testados foi encontrada na seguinte ordem: a aí (IA50 = 66,08 μg mL-1) > tucum > patauá > pracaxi > castanha do Brasil. Este estudo sugere que o óleo de a aí possui grande potencial para o tratamento da hiperpigmenta o cutanea e doen as correlatas, devido à sua considerável atividade de inibi o da tirosinase.
MORPHOMETRIC ANALYSIS OF THE DEVELOPMENT OF THE OVARIAN FOLLICLES IN PINEALECTOMIZED RATS ANáLISIS MORFORMéTRICO DEL DESARROLLO DE LOS FOLíCULOS OVáRICOS EN RATAS PINEALECTOMIZADAS
Katharine Raquel Pereira dos Santos,álvaro Aguiar Coelho Teixeira,Eulampio José da Silva Neto,Valéria Wanderley Teixeira
International Journal of Morphology , 2004,
Abstract: The present study had the objective of analyzing morphometrically the occupied area by the ovarian follicles in ovaries of pinealectomized female rats. To do so, 24 albino female rats (Rattus norvegicus albinus) were used, which were equally divided in the following groups: Group I - sham-pinealectomized rats and kept in the light/dark cycle (12/12 hours), for three months; Group II - pinealectomized rats and kept in the light/dark cycle (12/12 hours), for three months; Group III - pinealectomized rats and kept in the absence of light for three months; Group IV - sham-pinealectomized rats and kept in the absence of rats for three months. The results showed that the groups I and IV presented, respectively, average of 19,00 and 25,00, while groups II and III presented the highest average, 28,25 and 27,25, respectively, indicating, this way, a bigger occupied area by the follicles. It was observed a small amount of corpus luteum in the pinealectomized groups. So, we conclude that the pinealectomy can exert, in a certain period of time, some influence in the gonadal function, what might induce the formation of an anovulatory clinical patology and consequently the development of policystic ovaries El estudio tuvo como objetivo analizar morfométricamente el área ocupada por los folículos ováricos en ovarios de ratas pinealectomizadas. Para ello, 24 ratas albinas (Rattus norvegicus albinus), fueron divididas igualmente en los siguientes grupos: Grupo I - Ratas falsamente pinealectomizadas y mantenidas en el ciclo claro/oscuro (12/12 horas), por tres meses; Grupo II - ratas pinealectomizadas y mantenidas en el ciclo claro/oscuro (12/12 horas), por tres meses; Grupo III - ratas pinealectomizadas y mantenidas en la ausencia de luz durante tres meses; Grupo IV - ratas falsamente pinealectomizadas, y mantenidas en la ausencia de luz por tres meses. Los resultados mostraron que los grupos I y IV presentaban, respectivamente, medias de 19,00 y 25,00, mientras que los grupos II y III presentaron las mayores medias, 28,25 y 27,25, respectivamente, indicando mayor área ocupada por los folículos. Fue observada una peque a cantidad de cuerpos lúteos en los grupos pinealectomizados. De esta manera, concluimos que la pinealectomía puede ejercer, con el tiempo, alguna influencia en la función gonadal, lo que podrá inducir la formación de un cuadro clínico anovulatorio, y consecuentemente, el desarrollo de ovarios policísticos
Influência da altera??o da distribui??o do tamanho de partículas no desempenho de reator UASB tratando esgoto doméstico
Teixeira, Ana Raquel;Chernicharo, Carlos Augusto de Lemos;Souto, Tatiana Figueiredo da Silva;Paula, Fernando Silva de;
Engenharia Sanitaria e Ambiental , 2009, DOI: 10.1590/S1413-41522009000200003
Abstract: the work aimed at evaluating the performance of an uasb reactor treating domestic sewage pre-treated in a forced sieving unit (fsu) which resulted in size reduction of the influent organic matter particles. the experiments were carried out in two identical demonstration-scale uasb reactors, one with a fsu upstream and the other used as control reactor. the results showed that, after biomass adaptation to new kinetic and hydraulic conditions (low hydraulic detention time followed by high sludge load), the particles size reduction, in the range of 1.8 to 30 μm, resulted in a microbial community selection with higher activity (specific methanogenic activity of 0.072 g cod/g vts.day four times higher than in the control reactor). this enabled a better performance of the uasb reactor with the fsu, which showed a higher removal efficiency in terms of codtotal (65 versus 54% in the control reactor), and an effluent with lower concentration of codparticulate (48 versus 74 mg/l in the control reactor).
MORPHOMETRIC ANALYSIS OF THE DEVELOPMENT OF THE OVARIAN FOLLICLES IN PINEALECTOMIZED RATS
Pereira dos Santos,Katharine Raquel; Coelho Teixeira,álvaro Aguiar; da Silva Neto,Eulampio José; Teixeira,Valéria Wanderley; da Cunha,Franklin Magliano;
International Journal of Morphology , 2004, DOI: 10.4067/S0717-95022004000200001
Abstract: the present study had the objective of analyzing morphometrically the occupied area by the ovarian follicles in ovaries of pinealectomized female rats. to do so, 24 albino female rats (rattus norvegicus albinus) were used, which were equally divided in the following groups: group i - sham-pinealectomized rats and kept in the light/dark cycle (12/12 hours), for three months; group ii - pinealectomized rats and kept in the light/dark cycle (12/12 hours), for three months; group iii - pinealectomized rats and kept in the absence of light for three months; group iv - sham-pinealectomized rats and kept in the absence of rats for three months. the results showed that the groups i and iv presented, respectively, average of 19,00 and 25,00, while groups ii and iii presented the highest average, 28,25 and 27,25, respectively, indicating, this way, a bigger occupied area by the follicles. it was observed a small amount of corpus luteum in the pinealectomized groups. so, we conclude that the pinealectomy can exert, in a certain period of time, some influence in the gonadal function, what might induce the formation of an anovulatory clinical patology and consequently the development of policystic ovaries
Impacto da proteína-C reativa no risco cardiovascular de adolescentes
Silva, Isis Tande da;Sanches, Letícia Bertoldi;Mello, Ana Paula de Queiroz;Damasceno, Nágila Raquel Teixeira;
Arquivos Brasileiros de Cardiologia , 2010, DOI: 10.1590/S0066-782X2010005000027
Abstract: background: several studies suggest that c-reactive protein (crp) is associated with coronary artery disease in adults. however, this association has not been thoroughly explored in cases of adolescents. objective: to evaluate the association between crp and cardiovascular risk factors in obese adolescents. methods: eighty-four adolescents (12.6 ± 1.3 years) of both genders were divided into the following groups: normal weight (n = 28), overweight (n = 28), and obese (n = 28), according to body mass index (bmi). crp levels (ultrasensitive elisa), the lipid profile, and anti-oxldl antibody levels (elisa) were determined after a 12-hour fast. results: the groups were similar in age (p = 0.13) and gender (p = 0.83). total cholesterol, hdl-c, tc/hdl-c, and ldl-c/hdl-c showed significant differences between normal weight and obese groups. there was no significant variation in anti-oxldl levels. crp values were different among the three groups (p < 0.01). crp levels showed a significant association with bmi (β = 2.533), ac (β = 2.645), wc (β = 2.945), tc (β = 0.006), ldl-c (β = 0.006), and anti-oxldl antibodies (β = 0.383), and a negative association with hdl-c (β = -0.017). conclusion: the results indicate that crp is significantly associated with markers of cardiovascular risk in adolescents.
Inhibitory Effects of Resveratrol Analogs on Mushroom Tyrosinase Activity
Danielle Cristina Zimmermann Franco,Gustavo Senra Gon?alves de Carvalho,Paula Rafaela Rocha,Raquel da Silva Teixeira,Adilson David da Silva,Nádia Rezende Barbosa Raposo
Molecules , 2012, DOI: 10.3390/molecules171011816
Abstract: Skin pigmentation disorders typically involve an overproduction or uneven distribution of melanin, which results in skin spots. Resveratrol can inhibit tyrosinase, the active enzyme in the synthesis of melanin, but it does not inhibit the synthesis of melanin to an extent that enables its use alone as a skin whitening agent in pharmaceutical formulations, so its use as a coadjuvant in treatment of hyperpigmentation is suggested. Six resveratrol analogs were tested for tyrosinase inhibitory activity in vitro. Among the analogs tested, compound D was the most powerful tyrosinase inhibitor (IC50 = 28.66 μg/mL), two times more active than resveratrol (IC50 = 57.05 μg/mL), followed by the analogs A, E, B, F and C, respectively. This demonstrated that the hydroxylation at C4' on the phenolic ring was the molecular modification with most importance for the observed activity.
índice de infesta??o e diversidade de moscas-das-frutas em hospedeiros exóticos e nativos no pólo de fruticultura de Anagé, BA
, Ricardo Falc?o de;Castellani, Maria Aparecida;Nascimento, Antonio Souza do;Brand?o, Maria Heloisa da Silva Teixeira;Silva, Aline Novais da;Pérez-Maluf, Raquel;
Bragantia , 2008, DOI: 10.1590/S0006-87052008000200016
Abstract: fruit-flies (diptera: tephritidae) are the main hindrance for mango exportation in the fruitculture areas of the southwestern region of bahia. the purpose of the present work was to study the indexes of infestation and diversity of fruit-flies in the fruitculture area of anagé, ba, in order to obtain subsidies to the integrated management of these pests in mango, in this region. studies were carried out in 2004 and 2005 in the municipalities of anagé, belo campo and caraíbas, ba. fruit sampling from 21 native and exotic vegetable species, were analyzed for identification of species of associated fly species. infestation indexes in fruit weight (kg) and number of puparia were estimated. the obtained results demonstrated that the highest infestation indexes, in puparia/fruit kg, occurred in spanish prune (spondias purpurea l.) with 61,3, juá (ziziphus joazeiro l.) 38,3 and umbu (spondias tuberosa l.) , 33,1, which were considered primary hosts of the anastrepha fraterculus and a. obliqua. on the other hand, infestation, in puparia/kg of sampled fruit, occurred in spanish prune, 0,9 puparia/kg; umbu, with 0,7 and cajarana (spondias sp.) with 0,2. based on larval monitoring and under the conditions of the fruiticulture area in anagé, the occurrence of the following species have been recorded anastrepha fraterculus, a. obliqua, a. dissimilis, a. amita, a. distincta, a. sororcula, a. zenildae and ceratitis capitata has been recorded. for the first time, the following bitrophic associations: juá with a. fraterculus, a. obliqua, a. dissimilis and a. distincta; and umbu with a. amita and a. sororcula.
A a??o do decanoato de nandrolona (Deca-durabolin?) sobre parametros hematológicos e proteína total plasmática de ratos (Rattus rattus) com depress?o medular induzida após administra??o de sulfato de vincristina (Oncovin?)
Perez, Regina Raquel;Silva, Maria Adriana Machado Lobo e;Varzim, Fernanda Leme Silva Bastos;Oliveira, Sylvia Bonci de;Hucke, érica Engelberg Teixeira da Silva;
Ciência Rural , 2005, DOI: 10.1590/S0103-84782005000300015
Abstract: in veterinary practice it is common to submit animals to chemotherapy for neoplasia control and to observe bone marrow depression, with presence of anemia, leukopenia and thrombocytopenia as collateral effects. in these cases, two therapeutical protocols can be adopted: chemotherapy by suppression and/or use of bone marrow stimulants. nandrolone decanoate (deca-durabolin?) is a bone marrow stimulant used in veterinary medicine despite few studies were conducted in domestic animals. the objective of this study was to analyse nandrolone decanoate (nd-1,5mg/kg, intramuscular), as a bone marrow stimulant in rats (rattus rattus) with medular suppression induced by 4 and 8 mg/m2 (intraperitoneal) of vincristine (oncovin?). hemogram, platelets counting and total plasma protein determination were evaluated. these results showed that its effectiveness in bone marrow stimulation depends on the degree of depression and the dose of administration.
Disposi??o de adolescentes para a prática de esportes: um estudo orientado pela teoria bioecológica de Bronfenbrenner
Krebs, Ruy Jornada;Ramalho, Maria Helena da Silva;Santos, Jo?o Otacilio Libardoni dos;Nazario, Patrik Felipe;Nobre, Glauber Carvalho;Almeida, Raquel Teixeira;
Motriz: Revista de Educa??o Física , 2011, DOI: 10.5016/1980-6574.2011v17n1p195
Abstract: the present study aimed to analyze the adolescent's disposition for sports based in the bioecological paradigm of bronfenbrenner. the design of this study include two contexts (microsystems) with different environmental characteristics: (a) public school and (b) private school, both located on downtown of florianopolis. the results were organized according to two variables of the study: personal attributes (male or female) and context (public or private management). considering the proposed aim in this study, it was verified for the scholars which have participated of the research, the main motivational factor that led to sport were "health" and "fitness". therewith, the conclusion is that using a research model which takes into account the interaction between characteristics of the person, the context and the time is the most efficient model to study the adolescent's disposition for sports.
Complica??es pulmonares em crian?as submetidas à cirurgia cardíaca em um hospital universitário
Borges, Daniel Lago;Sousa, Lícia Raquel Teles;Silva, Raquel Teixeira;Gomes, Holga Cristina da Rocha;Ferreira, Fernando Mauro Muniz;Lima, Willy Leite;Borges, Lívia Christina do Prado Lui;
Revista Brasileira de Cirurgia Cardiovascular , 2010, DOI: 10.1590/S0102-76382010000200017
Abstract: objective: to identify the prevalence of pulmonary complications in children undergone cardiac surgery, as well as demographic and clinical characteristics of this population. methods: the sample comprised 37 children of both genders, underwent cardiac surgery at the hospital universitário presidente dutra, s?o luis (ma) during the year of 2007. there were not included patients who had lung disease in pre-operative period, patients with neurological disorders, intra-operative death besides lack of data in medical records. the data were obtained from general medical and nursing staff of their medical records. results: the population of the study was predominantly composed by female children, from the countryside and at school age. pathologies considered low risk were the majority, especially the patent ductus arteriosus, interventricular communication and interatrial communication. it was observed that the largest share of children made use of cardiopulmonary bypass for more than 30 minutes, with a median of 80 minutes, suffered a median sternotomy, using only the mediastinal drain and made use of mechanical ventilation after surgery, with the median about 6.6 hours. only three (8.1%) patients developed pulmonary complications, and of these, two died. conclusion: most of the sample was female, school aged and from the countryside. the low time of cardiopulmonary bypass and mechanical ventilation, and congenital heart disease with low risk, may have been factors that contributed to the low rate of pulmonary complications postoperative.
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