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Search Results: 1 - 10 of 112056 matches for " Rapoport Abr?o "
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Novo paradigma oncológico da cirurgia de cabe a e pesco o New oncologic paradigm in head and neck surgery
Abro Rapoport
Revista do Colégio Brasileiro de Cirurgi?es , 2010, DOI: 10.1590/s0100-69912010000400001
Abstract:
Estudo retrospectivo dos carcinomas epidermóides das vias aerodigestivas superiores com metástases bilaterais
Amar, Ali;Rapoport, Abro;
Revista do Colégio Brasileiro de Cirurgi?es , 2005, DOI: 10.1590/S0100-69912005000300008
Abstract: background: a descriptive study of the characteristics of squamous cell carcinoma of upper aerodigestive tract related to bilateral neck metastasis is established. methods: files of 150 patients with scc of mouth, oropharynx, larynx and hypopharynx who underwent bilateral neck dissection between january 1979 and december 1996, were reviewed, and 73 with histologic bilateral neck metastasis pn+ were selected. stage and location of the tumors were considered and results were analysed in front of lymphatic drainage and metastasis distribution studies. results: fourteen patients with primary tumor in stages t1 and t2, 57 in stages t3 and t4 and 2 were staged as tx. in 5 patients in stages t1 and t2 of the larynx with bilateral metastases, the lesion were localized in the epiglottis. conclusion: in patients with unilateral lesions with bilateral dissemination, all presented unilateral and palpable lesions.
Recidivas regionais nos pacientes com carcinoma epidermóide das vias aerodigestivas superiores submetidos à esvaziamento cervical
Amar, Ali;Rapoport, Abro;
Revista do Colégio Brasileiro de Cirurgi?es , 2003, DOI: 10.1590/S0100-69912003000200008
Abstract: background: to evaluate recurrence site in the neck of patients with squamous cell carcinoma of upper aerodigestive tract after neck dissection, as well as the results of salvage treatment. method: of 943 patients submitted to neck dissection, 95 were selected with diagnosis of neck recurrence as the first sign of relapse of disease. the location of neck disease (side and lymphatic level) and the control of disease after salvage treatment were evaluated. results: ipsilateral recurrences occured in level ii in 57% of patients. salvage treatment was accomplished in 51% of ipsilateral and in 75% of contralateral recurrences. control of disease after 12 months of salvage treatment was 31%, being 25% in ipsilateral and 37% in contralateral neck recurrences. conclusion: neck recurrence occur predominantly in level ii. relapse in level i is frequent only in oral cavity tumors, relapse in level v is rare. neck recurrence has poor outcome even among patients submitted to salvage treatment with curative intention.
Estudo da prevalência das doen?as tireoidianas em pacientes tireoidectomizados no Hospital da Santa Casa de Goiania
Roberti, Alexandre;Rapoport, Abro;
Revista do Colégio Brasileiro de Cirurgi?es , 2005, DOI: 10.1590/S0100-69912005000500002
Abstract: background: the state of goiás has left the position of an endemic goiter region in 1995. our objective is to study the correlation between histological diagnosis of thyroid diseases (endemic goiter, thyroiditis and cancer) and results of epidemiological enquiries. methods: retrospective analysis of 1399 patient files, who underwent thyroid surgery from 1993 to 2003 at the santa casa de misericórdia de goiania. results: we detected 1610 histological diagnosis: follicular adenoma in 155 (9.63%), others adenomas in 29 (1.80%), adenomatous goiter in 87 (5.40%), colloid goiter in 981 (60.9%), follicular carcinoma in 36 (2.24%), anaplastic carcinoma in 3 (0.19%), papillary carcinoma in 93 (5.78%), cysts in 9 (0.56%), toxic diffuse goiter in 75 (4.66%), others thyroiditis in 12 (0.75%), others malignancies in 6 (0.38%) and lymphocytic thyroiditis in 124 (7.71%). conclusions: there was a high prevalence of lymphocytic thyroiditis and papillary carcinoma, the same as usually observed in non endemic regions.
Metástases cervicais bilaterais no carcinoma epidermóide de cabe?a e pesco?o: tratamento cirúrgico em um ou dois tempos
Amar, Ali;Rapoport, Abro;Cervantes, Onivaldo;
Revista Brasileira de Otorrinolaringologia , 2004, DOI: 10.1590/S0034-72992004000100007
Abstract: aim: to assess the results of treatment of bilateral neck metastases in patients with squamous cell carcinoma of upper aerodigestive tract. study design: retrospective case-series. material and methods: the charts of 855 patients with squamous cell carcinoma of mouth, oropharynx, hypopharynx and larynx who underwent ressection of primary tumor and radical neck dissection were reviewed. ninety-six patients with histologically proven bilateral neck metastases were selected, 73 underwent bilateral radical neck dissection and 23 unilateral radical neck dissection and developed contralateral recurrence. the free disease survival and neck control rates were evaluated. results: between 23 patients who underwent unilateral neck dissection and developed contralateral recurrence, only 18 were salvaged. the neck control after 2 years was achieved in 46% of patients. between 73 patients who underwent bilateral neck dissection, 12 cases of neck recurrences were diagnosed and only 3 patients were salvaged. the neck control after 2 years was 77%, and the free disease survival was similar between the 2 groups, despite of the difference in neck control rates. conclusion: the bilateral neck dissection in one stage was more effective to control neck disease but no difference of disease-free survival in comparison with two stage procedure was observed. neck control was reached in most patients, but only 35% of those with bilateral metastases were free of disease after 2 years.
The desmoplastic limph node reaction as a prognostic factor of cancer of the tongue and floor of the mouth.
Lehn, Carlos Neutzling;Rapoport, Abro;
Sao Paulo Medical Journal , 1994, DOI: 10.1590/S1516-31801994000300004
Abstract: to determine the prognostic significance of desmoplasia in metastatic lymph nodes of squamous cell carcinoma of the oral tongue and floor of mouth, 37 cases of this disease were studied. desmoplasia was present in 59,4% of the cases and associated extracapsular spread in 40,5%. the association of desmoplasia with large lymph node involvement occurred in 59,4%. these relationships were statistically significant (p= 0,002 and 0,0069). the results obtained suggest that desmoplasia is a bad prognosis associated factor.
Metástases cervicais bilaterais no carcinoma epidermóide de cabe a e pesco o: tratamento cirúrgico em um ou dois tempos
Amar Ali,Rapoport Abro,Cervantes Onivaldo
Revista Brasileira de Otorrinolaringologia , 2004,
Abstract: OBJETIVO: Avaliar os resultados do tratamento dos pacientes com metástases cervicais bilaterais de carcinoma epidermóide das vias aerodigestivas superiores. FORMA DE ESTUDO: Série de casos retrospectiva. CASUíSTICA E MéTODO: Revis o dos prontuários de 855 pacientes com carcinoma epidermóide de boca, orofaringe, hipofaringe e laringe submetidos à ressec o do tumor primário e esvaziamento cervical radical entre 1977 e 1996. Foram selecionados 96 pacientes com metástases bilaterais confirmadas histologicamente, dos quais 73 foram submetidos inicialmente ao esvaziamento cervical bilateral (ECB) e 23 pacientes que se submeteram ao esvaziamento unilateral e, posteriormente, desenvolveram recidiva cervical contralateral. A evolu o dos pacientes foi avaliada por meio da sobrevida livre de doen a e do controle cervical. RESULTADOS: Entre os 23 pacientes submetidos ao esvaziamento unilateral (pN+) que desenvolveram recidiva contralateral, foram resgatados 18 pacientes. O controle da doen a no pesco o em 2 anos foi alcan ado em 46% dos pacientes. Entre os 73 pacientes submetidos ao esvaziamento bilateral (pN2c) ocorreram 12 casos de recidivas cervicais, dos quais apenas 3 foram resgatados. O controle da doen a no pesco o em dois anos foi alcan ado em 77% dos pacientes. A sobrevida livre de doen a foi semelhante entre os 2 grupos, apesar da diferen a observada na taxa de controle cervical. CONCLUS O: O esvaziamento bilateral em tempo único apresentou melhor controle da doen a no pesco o, mas n o alterou a sobrevida livre de doen a neste grupo de pacientes. A despeito do controle da doen a cervical ser obtido na maioria dos pacientes, apenas um ter o daqueles com metástases bilaterais apresentaram doen a controlada após 2 anos.
Metastatiza??o linfática oculta no carcinoma epidermóide das vias aerodigestivas superiores
Amar, Ali;Carvalho, Marcos B.;Rapoport, Abro;
Revista Brasileira de Otorrinolaringologia , 2002, DOI: 10.1590/S0034-72992002000400017
Abstract: introduction: elective neck dissections are procedures to identifiy occult neck node metastases in head and neck cancer. study design: clinical retrospective. aim: evaluate occult metastasis in neck nodes in patients with head and neck squamous cell carcinoma. material and method: from 1977 to 1996, 428 patients submitted to elective neck dissection were evaluated, concerning the incidence of false negatives neck nodes (pn+), and its relation to the size (stage t), anatomic location, histologic graduation, sex, age and main lymphatic chains affected. results: occult metastasis were diagnosed in 32%, being 26% for larynx, 31% for orophaynx, 36% for oral cavity and 40% for hipopharynx. the level i and iv were predominant, and the level i only for the oral cavity. between patients with occult metastasis, 56% presented multiples chains with metastasis. the stage i were related only with larynx tumors. conclusions: the lymphatcs levels ii and iii were predominant for pharynx and larynx and the level i for the oral cavity. the others risk factors (age, gender and hystologic degree differenciation) were not responsible for occult metastases.
Valor do padr?o de estimula?ao linfonodal da metástase no prognóstico do cancer da hipofaringe: estudo de 24 casos
Fleitas, Marta Elizabeth Osório;Rapoport, Abro;
Revista do Colégio Brasileiro de Cirurgi?es , 1998, DOI: 10.1590/S0100-69911998000500004
Abstract: twenty four patients with squamous cell carcinoma of the hypopharnx treated at the head and neck surgery service of the heliópolis hospital from january 1977 to january 1993. were studied. thirteen cases had no lymphatic metastases (pno) and eleven had lymph nade metastases without extracapsular spread (pn+rc-). clinical and histological standards of both groups were compared with survival. clinical data were obtained by reviewing patients registers and histological data by reviewing histological slides. age, sex, n stage, clinical stage and cervical recurrence had no statistically significant relation with prognosis in both groups. patients were divided in two groups according to the lymph node reactional pattern: (lymphocyte and germinal center predominance) and unstimulated. results showed that patients with positive lymph node without extracapsular spread (pn+rc-) had a higher percentage of stimulated lymph nodes than the group without lymphatic metastases (p=0,0333).
Significado prognóstico do linfonodo metastático N3 em carcinomas epidermóides de cabe?a e pesco?o
Amar, Ali;Curioni, Otávio Alberto;Rapoport, Abro;
Revista do Colégio Brasileiro de Cirurgi?es , 2004, DOI: 10.1590/S0100-69912004000100007
Abstract: background: we assessed the results of therapy for advanced lymph node metastases (n3) and its relation with the prognosis of squamous cell carcinoma of the head and neck. methods: files of 241 patients with squamous cell carcinoma of the mouth, oropharynx, larynx and hipopharynx with advanced metastatic lymph nodes (n3), submited to surgery and/or radiotherapy, were reviewed at the head and neck and otorhinolaryngology department of hospital heliópolis, hosphel, s?o paulo (1988 to 1998). for the surgical group, complete or incomplete resection was evaluated and for the irradiated group the responsiveness at the end of the therapy was analysed. disease- free survival for the first group was evaluated using kaplan-meier. results: the unresecability of the neoplasia justified the radiotherapy at medium dose of 65 gy for 69 patients, with complete response at primary lesion in 24(36%), and at the neck in 12(18%), and for both sites in 11(16%). for the surgical group followed by irradiation, the medium dose was 56 gy. from 25 patients submitted to radical resection of the neck, five (20%) presented recurrence, and the five cases with partial resection and radiotherapy, two presented a global survival from seven to 12 mouths. for the surgical group, disease-free survival for two years was 58%. conclusions: for patients with n3 neck node metastases, neck dissection, followed by radiotherapy, was effective for disease regional control, while, for inoperable cases, radiotherapy was only a paliative method.
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