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Search Results: 1 - 10 of 225824 matches for " Rajani R. Joshi "
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Automated Pulse-Based Diagnosis: Role of TIM Diagnostic Features  [PDF]
Rajani R. Joshi
Journal of Biomedical Science and Engineering (JBiSE) , 2014, DOI: 10.4236/jbise.2014.710076
Abstract: Emanated from the idea of reinvestigating ancient medical system of Ayurveda—Traditional Indian Medicine (TIM), our recent study had shown significant applications of analysis of arterial pulse waveforms for non-invasive diagnosis of cardiovascular functions. Here we present results of further investigations analyzing the relation of pulse-characteristics with some clinical and pathological parameters and other features that are of diagnostic importance in Ayurveda.
Automatic detection of pulse morphology patterns & cardiac risks  [PDF]
Rajani R. Joshi, Ganesh B. Nawsupe, Smita P. Wangikar
Journal of Biomedical Science and Engineering (JBiSE) , 2012, DOI: 10.4236/jbise.2012.56041
Abstract: Analysis of arterial pulse waveforms is important for non-invasive diagnosis of cardiovascular functions. Large samples of IPG signal records of radial arterial pulse show presence of eight different types of shapes (morphological patterns) in the pulse waveforms. In this paper we present an efficient computational method for automatic identification of these morphological patterns. Our algorithm uses likelihood ratio of cumulative periodogram of pulse signals and some geometrical criteria. The algorithm is presented with necessary details on signal processing aspects. Results for a large sample of pulse records of adult Indian subjects show high accuracy of our algorithm in detecting pulse-morphology patterns. Variation of pulse-morphology with respect to time is also analyzed using this algorithm. We have identified some characteristic features of pulse-morphology variation in patients of certain cardiac problems, hypertension, and diabetes. These are found relevant and significant in terms of physiological interpretation of the associated shapes of pulse waveforms. Importance of these findings is highlighted along with discussion on overall scope of our study in automatic analysis of heart rate variability and in other applications for non-invasive prognosis/diagnosis.
Oligodynamic Action of Silver, Copper and Brass on Enteric Bacteria Isolated from Water of Kathmandu Valley
Rajani Shrestha,Dev Raj Joshi,Jyotsna Gopali,Sujan Piya
Nepal Journal of Science and Technology , 2009, DOI: 10.3126/njst.v10i0.2959
Abstract: Traditionally certain metal pots are used to store drinking water in order to ensure safety. A study was conducted with the aim of evaluating the effect of oligodynamic metals such as copper, silver and brass against enteric gram negative drinking water isolates such as Salmonella paratyphi , Shigella spp., E. coli (MDR), E. coli, Vibrio cholerae and Klebsiella during September 2007 to January 2008. The test was carried out by preparing broth of the respective microorganisms followed with contaminating autoclaved distilled water with 1% (by volume) of the prepared broth culture and incubating the contaminated water in the respective metal pots up to 48 h (holding time). Reduction in the microbial load was assessed by pour plating the water content in the metal pots on Nutrient agar medium in every 0, 4th, 8th, 12th, 24th and 48th h of incubation (holding time). Among three test pots, copper pot showed the maximum bactericidal action compared to silver and brass pots towards most of the enteric gram negative bacterial isolates of water. Complete inhibition of tested organism was recorded within 4 to 48 hours of holding time. This study suggested the promotion of use of water pots made of oligodynamic metals such as silver and copper, and alloy such as brass to control the gram negative enteric pathogens in drinking water. Key words: Oligodynamic action; Heavy metals; Enteric bacteria DOI: 10.3126/njst.v10i0.2959 Nepal Journal of Science and Technology Vol. 10, 2009 Page: 189-193 ? ? ?
Analgesic and Anti-Ulcer Activities of Ethanol and Aqueous Extracts of Root of Bauhinia variegata Linn.
Yamini R. Kumar,G.P. Rajani
International Journal of Pharmacology , 2011,
Abstract: The present study was aimed at evaluating analgesic and antiulcer activities of the ethanolic (BVE) and aqueous (BVA) extracts of root of Bauhinia variegata Linn., respectively in animal models. The analgesic activity was evaluated for its central and peripheral pharmacological actions by using Eddys hot plate method and acetic acid-induced writhing, respectively. The anti-ulcer activity was evaluated by using pylorus ligation, ethanol and aspirin induced ulcer models. The study was carried out in two different dose levels of 200 and 400 mg kg-1 body weight orally for both ethanolic and aqueous extracts, respectively. BVE and BVA did not produce any mortality up to 2000 mg kg-1. Dose dependent increase in latency of response in the hot plate method was observed with BVE 400 mg kg-1 and 81% inhibition in acetic acid induced writhings in mice was observed with BVA 400 mg kg-1. BVE and BVA at both the doses showed 99% protection in ethanol induced ulcer model. BVE 400 mg kg-1 showed 99.9% protection in aspirin induced ulcer model. Both BVE and BVA at the dose of 400 mg kg-1 showed 99.8% protection in pylorus ligation ulcer model. Pharmacological screening of the root extracts of Bauhinia variegata Linn. showed significant (p<0.001) dose dependent analgesic activity and significant (p<0.001) anti-ulcer activity when compared with reference standard. Presence of flavonoids might be responsible for these activities. NSAIDs are associated with side effects of gastric ulcers. BVE and BVA are reported to be plant-derived natural remedy having analgesic and anti-ulcer activities.
The Effect of Mass Ratio and Air Damper Characteristics on the Resonant Response of an Air Damped Dynamic Vibration Absorber  [PDF]
R. G. Todkar, S. G. Joshi
Modern Mechanical Engineering (MME) , 2011, DOI: 10.4236/mme.2011.12012
Abstract: In this paper, it is shown that, a road vehicle 2DOF air damped quartercar suspension system can conveniently be transformed into a 2DOF air damped vibrating system representing an air damped dynamic vibration absorber (DVA) with an appropriate change in the ratio µ of the main mass and the absorber mass i.e. when mass ratio µ >> 1. Also the effect of variation of the mass ratio, air damping ratio and air spring rate ratio, on the motion transmissibility at the resonant frequency of the main mass of the DVA has been dis- cussed. It is shown that, as the air damping ratio in the absorber system increases, there is a substantial decrease in the motion transmissibility of the main mass system where the air damper has been modeled as a Maxwell type. Optimal value of the air damping ratio for the minimum motion transmissibility of the main mass of the system has been determined. An experimental setup has been designed and developed with a control system to vary air pressure in the damper in the absorber system. The motion transmissibility characteristics of the main mass system have been obtained, and the optimal value of the air damping ratio has been determined for minimum motion transmissibility of the main mass of the system
Ecosystem Responses in the Distribution of Black Clam (Villorita cyprinoides) Beds in Vembanad Estuary during Environmental Changes Using GIS and RS  [PDF]
Thankam Theresa Paul, Grinson George, A. Dennis, N. R. Athira, R. S. Biradar, Rajani Khandagale, K. G. Padmakumar
Journal of Geographic Information System (JGIS) , 2017, DOI: 10.4236/jgis.2017.93015
Abstract: The biomass and distribution of black clam (Villorita cyprinoides) in Vembanad, a tropical estuary located along the southwest coast of India varied significantly. Sampling was done in freshwater-dominated zone in the south (distal) and brackish water zone in the north (proximal), during pre and post monsoon seasons. Clam biomass was estimated from samples, collected from different stations during the study period. Water transparency and temperature were measured at the sample sites. Water samples were collected and analysed for salinity, dissolved oxygen (DO), pH and hardness. There was a significant difference in the clam biomass during the two seasons in the distal zone, and those collected from the distal and proximal zones during pre-monsoon season. The data were further analysed to determine the factors affecting the clam biomass distribution in the two zones and seasons. Factor analyses, comparing the distal zone during two seasons and zonal variations were similar to earlier observations. Step wise regression analyses found that dissolved oxygen (adjusted R2 = 0.3) is the only variable affecting clam survival during pre-monsoon period in the distal and proximal zones. A geographic map of the region obtained from the Indian satellite sensor LISS (Linear Image Self Scanner) was used along with in situ data to map the results using inverse distance weightage model.
Significance of tumour markers in cancer of gall bladder  [PDF]
Sharada R. Kankonkar, S. V. Joshi, R. R. Deshpande
Open Journal of Immunology (OJI) , 2013, DOI: 10.4236/oji.2013.31005
Abstract: In India, GI tract cancer is one of the ten leading cancers. Among Indian males it stands second to oral cancer and in females, it shares the third place. Most common malignant disorder of GIT is seen in our country that of liver, bile, gall bladder, pancreas, bileduct and colorectal. Aim: To see the significance of tumour markers in gall bladder cancer. Materials and Methods:This study comprise 225 cases of GI tract cancers was carried for more than two years. Of these, 22 subjects had gallbladder cancer. Tumour markers viz. CA19-9, CEA and AFP were assayed pre and post-operative cases and their role in gallbladder cancer was evaluated. Results: It was observed that serum concentration of CA 19-9 increased with advancing stage, but the same is not true for AFP and CEA. Sensitivity of these markers AFP, CA 19-9 and CEA in the detection of gall bladder cancer was determined. CA 19-9 is the most sensitive of all the three tumour markers in the detection of gall bladder cancer. Conclusion: The combination of CA19-9 and CT (or US) is a reasonable, cost-effective, noninvasive approach to establishing the diagnosis of pancreatic, cholangitic, or biliary cancer in nonicteric patients.
Generalized Laplace transform with matrix variables
R. M. Joshi,J. M. C. Joshi
International Journal of Mathematics and Mathematical Sciences , 1987, DOI: 10.1155/s0161171287000590
Abstract: In the present paper we have extended generalized Laplace transforms of Joshi to the space of m —m symmetric matrices using the confluent hypergeometric function of matrix argument defined by Herz as kernel. Our extension is given by g(z)= “m( ±) “m( 2) ¢ ¢ §>01F1( ±: 2: ¢ ’ ¢ §z) ¢ € ‰f( ¢ §)d ¢ §
Effect of amitriptyline vs. physiotherapy in management of fibromyalgia syndrome: What predicts a clinical benefit?
Joshi M,Joshi R,Jain A
Journal of Postgraduate Medicine , 2009,
Abstract: Context : Fibromyalgia is a chronic disabling condition, and physicians treat it using a number of different treatment modalities. It is not known if one or more of such modalities are better than the others. We compared the efficacy of physiotherapy and amitriptyline in disability reduction in patients of fibromyalgia syndrome in a rural tertiary care hospital in Central India. Design : Open-label alternate patient treatment allocation. Materials and Methods : A six-month follow-up was done to assess the benefit of amitriptyline and physiotherapy for disability reduction in patients with fibromyalgia syndrome. Primary outcome measure was improvement in fibromyalgia impact questionnaire (FIQ) score. Statistical Analysis Used : Predictors of benefit were determined using multivariate logistic regression. Results : A total of 175 outpatients were assigned to either amitriptyline (n=87) or structured physiotherapy (n=88) treatments. There was a significant but similar (P=0.82) improvement in disability in both groups. High FIQ score at baseline and low socioeconomic status scores were significant predictors of benefit. Conclusions : Therapy with amitriptyline or physiotherapy is equally effective in improving outcome in patients of fibromyalgia over a period of six months.
Some Plants used in Ayurvedic and Homoeopathic Medicine
Veena Joshi,R.P.Joshi
Journal of Pharmacognosy and Phytochemistry , 2013,
Abstract: Traditional medicines are used by about 60% of the world’s population. These are used for primary health care, not only in rural areas of developing nations but they are also used in the developed countries where modern medicine are pre dominantly used. In the western world the use of medicinal herbs is continuously growing, approximately 40% of the population is using herbs for medical illness due to increased incidences of adverse effects of allopathic medicine. There are about 45000 plant species in India, Eastern Himalayas, Western Ghats and Andman and Nicobar Islands are the hot spot for medicinal plants. Officially documented plants with medicinal potential are 3000 but traditional practitioner use more than 6000. Seventy percent of the population in the rural India is dependent on the ayurvedic system of medicine. Most of the drugs used in modern medicine and ancient Indian medicinal system are of plant origin. Beside plants many minerals, salts and animal products are used in Ayurvedic medicines. Homoeopathy originated in west, German physician Samuel Hanemann was the father of homoeopathy (1796), the homeopathic remedies are prepared by successive dilution followed by shaking forcefully. Homoeopathy uses animal, plant, mineral, and synthetic substances in its remedies. Arsenicum album (arsenic oxide), Natrum muriaticum (sodium chloride), opium (plant), and thyroidinum (thyroid hormone) are some of the homoeopathic medicines extracted from different sources.
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