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Search Results: 1 - 10 of 46676 matches for " Raj Michael Karunai "
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Antimicrobial, antimycobacterial and antibiofilm properties of Couroupita guianensis Aubl. fruit extract
Al-Dhabi Naif Abdullah,Balachandran Chandrasekar,Raj Michael Karunai,Duraipandiyan Veeramuthu
BMC Complementary and Alternative Medicine , 2012, DOI: 10.1186/1472-6882-12-242
Abstract: Background Couroupita guianensis Aubl. (Lecythidaceae) is commonly called Ayahuma and the Cannonball tree. It is distributed in the tropical regions of northern South America and Southern Caribbean. It has several medicinal properties. It is used to treat hypertension, tumours, pain, inflammatory processes, cold, stomach ache, skin diseases, malaria, wounds and toothache. Methods The fruits of Couroupita guianensis were extracted with chloroform. Antimicrobial, antimycobacterial and antibiofilm forming activities of the chloroform extract were investigated. Quantitative estimation of Indirubin, one of the major constituent, was identified by HPLC. Results Chloroform extract showed good antimicrobial and antibiofilm forming activities; however it showed low antimycobacterial activity. The zones of inhibition by chloroform extract ranged from 0 to 26 mm. Chloroform extract showed effective antibiofilm activity against Pseudomonas aeruginosa starting from 2 mg/mL BIC, with 52% inhibition of biofilm formation. When the chloroform extract was subjected to HPLC-DAD analysis, along with Indirubin standard, in the same chromatographic conditions, it was found that Indirubin was one of the major compounds in this plant (0.0918% dry weight basis). Conclusions The chloroform extract showed good antimicrobial and antibiofilm properties. Chloroform extract can be evaluated further in drug development programmes.
Analytical expression of non steady-state concentration profiles at planar electrode for the CE mechanism  [PDF]
Vincent Michael Raj Margret PonRani, Lakshmanan Rajendren
Natural Science (NS) , 2010, DOI: 10.4236/ns.2010.211160
Abstract: The analytical solutions of the non-steady-state concentrations of species at a planar microelectrode are presented. These simple new approximate expressions of concentrations are valid for all values of time and possible values of rate constants. Analytical equations are given to describe the current when the homogeneous equilibrium position lies heavily in favour of the electroinactive species. Working surfaces are presented for the variation of limiting current with a homogeneous kinetic parameter and equilibrium constant. Moreover, in this work we employ the Homotopy perturbation method to solve the boundary value problem.
Obstructive Sleep Apnea and Post-Operative Complications: Single Center Data, Review of Literature and Guidelines for Practicing Internists and Surgeons  [PDF]
Kenneth M. Nugent, Michael Phy, Rishi Raj
Surgical Science (SS) , 2012, DOI: 10.4236/ss.2012.32012
Abstract: Obstructive sleep apnea has been linked to higher rates of post-operative complications in some studies. We examined the prevalence of obstructive sleep apnea and its impact on post-operative complications in 125 patients (21 prospective, 104 retrospective) undergoing various elective outpatient surgeries at our institution. Ten percent of these patients had OSA, and half of them were on continuous positive airway pressure therapy (CPAP). Patients who were on CPAP as outpatients received CPAP post-operatively as well. No patients died, and the prevalence of post-operative complications was low. There was no difference in complication rates between patients with and without OSA. We also review the existing literature on this subject and make practical recommendations regarding pre-operative evaluation and post-operative management of these patients for practicing internists and surgeons based on the current literature.
Implementation of ML Using Na ve Bayes Algorithm for Identifying Disease-Treatment Relation in Bio-Science Text
T.F. Michael Raj,S. Prasanna
Research Journal of Applied Sciences, Engineering and Technology , 2013,
Abstract: In recent years many successful machine learning applications have been developed, ranging from datamining programs to information-filtering systems that learn users' reading preferences. At the same time, there have been important advances in the theory and algorithms that can be used identify the diseases and treatment relations in a Bio-Science text. Imagine a computer learns from medical records which treatments are most effective for new diseases. Having the machine learning concept behind we have proposed a Machine Learning (ML) approach based on Na ve Bayes (NB) algorithm to improve the automatic disease identification in the medical field. And also we have improved text classification by using an integrated model.
On the Design of Circular Fractal Antenna with U-Shape Slot in CPW-Feed  [PDF]
Raj Kumar
Wireless Engineering and Technology (WET) , 2010, DOI: 10.4236/wet.2010.12012
Abstract: A new ultawideband circular fractal antenna with notched-band characteristics is presented. A notched-band characteristic is achieved by employing a U-shape slot in 50 Ω feed lines. The ultra-wideband impedance matching and compact size have been obtained by using CPW-feed technique and the fractal concept. The measured result of proposed fractal antenna exhibits the ultra wideband characteristics from 3.0 to 18.0 GHz at VSWR 2:1 except notched-band frequency. The proposed antenna has been analyzed theoretically and experimentally with respect to design parameters. The measured radiation pattern of fractal antenna is nearly omnidirectional in azimuth plane throughout the operating frequency. This antenna is useful for UBW communication system.
Impact of Forecast Errors in CPFR Collaboration Strategy  [PDF]
Raj Kamalapur
American Journal of Industrial and Business Management (AJIBM) , 2013, DOI: 10.4236/ajibm.2013.34046

The primary objective of this research is to investigate the impact of random forecast error and bias forecast error in Collaborative Planning, Forecasting and Replenishment (CPFR) strategy on the cost of inventory management for both the manufacturer and retailer. Discrete-event simulation is used to develop a CPFR collaboration model where forecast, sales and inventory level information is shared between a retailer and a manufacturer. Based on the results of this study, we conclude that the higher random forecast error and negative bias forecast error increases the cost of inventory management for both the manufacturer and the retailer. When demand variability is high, a bias forecast error has a bigger impact on inventory management cost compared to a random forecast error for both the manufacturer and retailer. Also, a positive bias forecast error is more beneficial than a negative bias forecast error to gain maximum benefits of CPFR strategy.

Sustainable Urban Habitats and Urban Water Supply: Accounting for Unaccounted for Water in Bangalore City, India  [PDF]
Krishna Raj
Current Urban Studies (CUS) , 2013, DOI: 10.4236/cus.2013.14017
Abstract: The demand for urban water supply service is increasing rapidly as globalisation accelerates economic development and brings improvements in living standards in India with the interactive effects of demographic growth and influx of migrants into cities due to push and pull factors. Provision of reliable and safe water supply to urban habitat is an essential input for overall economic and social advancement. However, urban local bodies mandated to perform this task in India have been experiencing constant budgetary bottlenecks in mobilizing resources to meet the water consumption targets of the present as well as future population. Urban water supply sector in India and particularly the study area Bangalore is facing a number of challenges and constraints in meeting one of the important components of the United Nations’ Millennium Development Goals (MDGs), i.e., to ensure supply of adequate potable water to half the number of people who are currently living without access to sustainable, safe drinking water sources by 2015. These problems and constraints include increasing scarcity of water, low pricing, high subsidy, poor cost recovery, high transmission and distribution (T & D) losses, due to poor maintenance, rising unaccounted-for (UFW) and non-revenue water outgo (NRW). Bangalore Water Supply and Sewerage Board (BWSSB) is experiencing poor cost recovery and has been unable to generate enough revenue to meet the investment requirements of the growing water needs of the city. BWSSB is also facing serious performance gaps such as reliability, financial sustainability, environmental sustainability and affordability due to deterioration of infrastructure.
Efficacy and Safety of Antipsychotics for the Treatment of Major Depressive Disorder in Adolescents and Adults: Current Issues and Clinical Perspective  [PDF]
Raj Rasasingham
Open Journal of Psychiatry (OJPsych) , 2014, DOI: 10.4236/ojpsych.2014.43024

Objectives: Atypical antipsychotics are increasingly being prescribed for the treatment of mood disorders, often off-label. This review describes existing published literature on the efficacy and safety of antipsychotics for the treatment of major depressive disorder (MDD) in adults and adolescents. We discuss current clinical considerations: role as monotherapy, adjunctive, or augmentation therapy, side effect profiles, and optimal dose and duration of therapy. Potential areas for future research and methodological considerations are also highlighted. Method: We conducted a literature search of MEDLINE, EMBASE, PsycINFO, and Cochrane databases. Relevant articles and references were identified. MDD practice guidelines for adolescents and adults were reviewed. Results: Evidence for using atypical antipsychotics to treat MDD is heterogeneous. It is thus difficult to draw firm conclusions regarding their role in therapy. Most current guidelines do not include recommendations for atypical antipsychotics, but off-label use is common in clinical practice. Primary use is adjunct or augmentation therapy for treatment resistant depression. Potential benefits versus side effects must be cautiously considered, especially for children and adolescents. Clinicians must rely on their clinical experience and professional judgment to determine an optimal dose and duration of therapy. Conclusions: There is progressive research to support the use of atypical antipsychotics to treat MDD in adults. However, additional research and well-designed studies are needed to determine the appropriate and safe use of atypical antipsychotics for treating child and adolescent depression. Other subpopulations that may benefit from combination therapy, such as individuals with dual diagnoses, may be identified through future research.

A Linear Regression Approach for Determining Explicit Expressions for Option Prices for Equity Option Pricing Models with Dependent Volatility and Return Processes  [PDF]
Raj Jagannathan
Journal of Mathematical Finance (JMF) , 2016, DOI: 10.4236/jmf.2016.62026
Abstract: We consider a risk-neutral stock-price model where the volatility and the return processes are assumed to be dependent. The market is complete and arbitrage-free. Using a linear regression approach, explicit functions of risk-neutral density functions of stock return functions are obtained and closed form solutions of the corresponding Black-Scholes-type option pricing results are derived. Implied volatility skewness properties are illustrated.
A Linear Regression Approach for Determining Option Pricing for Currency-Rate Diffusion Model with Dependent Stochastic Volatility, Stochastic Interest Rate, and Return Processes  [PDF]
Raj Jagannathan
Journal of Mathematical Finance (JMF) , 2018, DOI: 10.4236/jmf.2018.81013
Abstract: A three-factor exchange-rate diffusion model that includes three stochastically-dependent Brownian motion processes, namely, the domestic interest rate process, volatility process and return process is considered. A linear regression approach that derives explicit expressions for the distribution function of log return of foreign exchange rate is derived. Subsequently, a closed form workable formula for the call option price that has an algebraic expression similar to a Black-Scholes model, which facilitates easier study, is discussed.
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