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Comparison of vitamin D levels in obese and non obese patients with polycystic ovarian syndrome in a South Indian population
Lakshmi R. Lakshman,Binu Parameswaran Pillai,Rahul Lakshman,Harish Kumar
International Journal of Reproduction, Contraception, Obstetrics and Gynecology , 2013, DOI: 10.5455/2320-1770.ijrcog20130915
Abstract: Polycystic ovary syndrome (PCOS) is the most common metabolic abnormality occurring in young women of reproductive age. Low vitamin D levels were found to be associated with the development of obesity and insulin resistance in young women with PCOS. The study was conducted as a prospective observational study involving 121 women with PCOS. The diagnosis of PCOS cases were based on the revised Rotterdam consensus criteria. Vitamin D levels were compared in the obese and non obese PCOS groups and also with the controls. In the PCOS group, sixty subjects were obese with BMI of ≥25 kg/m2 and forty seven subjects were found to be non obese. In the control group, sixteen subjects were obese and sixty five subjects were non obese. The mean vitamin D level in the PCOS group was 15.45±7.88 ng/ml and in the control group was 12.83±5.76ng/ml. The mean vitamin D levels in the obese and non obese group with PCOS were 16.11±8.9ng/ml and 14.61±6.1ng/ml respectively. Majority of the patients and controls had vitamin D deficiency and there was no difference in the vitamin D levels in PCOS group and controls as well as obese and non obese groups. [Int J Reprod Contracept Obstet Gynecol 2013; 2(3.000): 336-343]
A comparative study of verbal IQ, performance IQ and verbal IQ-performance IQ disparity among Turner syndrome patients and patients with primary amenorrhoea due to other aetiologies
Lakshmi R. Lakshman,Rahul Lakshman,D. M. Vasudevan
International Journal of Reproduction, Contraception, Obstetrics and Gynecology , 2012, DOI: 10.5455/2320-1770.ijrcog001212
Abstract: Background: Assessing disparity in IQ is important in selecting an occupation and thus helping people lead a productive life. In Turner syndrome patients, this shall be more important as assessment of verbal IQ- and performance IQ disparity could be used in helping them select an occupation so that productivity and quality of life is not grossly compromised. Methods: Based on karyotyping, 30 patients with turner syndrome and 30 patients with primary amenorrhoea due to other aetiologies were selected for the study. Cytogenetic analysis was done for every case using G-banding technique. Assessment of intellectual functions was done using Wechsler Adult Intelligence Scale (WAIS). Results: Mean value of PIQ of X0 (turner) was 74.67 and that of XX (other amenorrhoea patients) was 90.30. Mean value of VIQ of X0 (turner) was 93.67 and that of XX (other amenorrhoea patients) was 93.60. Mean value of VIQ and PIQ disparity of X0 (turner) was 18.67 and that of XX (other amenorrhoea patients) was 3. Conclusions: Turner syndrome patients have high VIQ-PIQ disparity when compared to other primary amenorrhoea patients. [Int J Reprod Contracept Obstet Gynecol 2012; 1(1.000): 22-25]
Quantitative Geomorphometrics for Terrain Characterization  [PDF]
David Coblentz, Frank Pabian, Lakshman Prasad
International Journal of Geosciences (IJG) , 2014, DOI: 10.4236/ijg.2014.53026

The relationship between geology and landforms has long been established with quantitative analysis dating back more than 100 years. The surface expression of various subsurface lithologies motivates our effort to develop an automated terrain classification algorithm based solely on topographic information. The nexus of several factors has recently provided the opportunity to advance our understanding of the relationship between topography and geology within a rigorous quantitative framework, including recent advances in the field of geomorphometrics (the science of quantitative land surface analysis), the availability of very high resolution (sub meter) digital elevation models, and increasing sophisticated geomorphology and image analysis techniques. In the present study, the geological and geomorphological units in an exemplar study area located in Western U.S. (southern Nevada) have been delineated through an evaluation of a high resolution (1-meter and 0.25-meter) digital elevation model. The morphological aspects of these features obtained from DEMs generated from different sources are compared. Our analysis demonstrates that a 1-meter DEM can provide a terrain characterization that can differentiate underlying lithological types and a very high resolution DEM (0.25 meter) can be used to evaluate fracture patterns.

Unified Payment Interface—An Advancement in Payment Systems  [PDF]
Rahul Gochhwal
American Journal of Industrial and Business Management (AJIBM) , 2017, DOI: 10.4236/ajibm.2017.710084
Abstract: This paper studies Unified Payment Interface (UPI), a new age payment system introduced in India by National Payment Corporation of India. Unified Payment Interface is a mobile centric, real time interbank payment system which has the potential to transform and universalize digital payments in India. The paper traces the evolution of payments systems in India and examines in detail the technology behind Unified Payment Interface focusing on its architecture and security systems through empirical and theoretical literature review. UPI is a significant advancement as compared to extant payment system in terms of cost, ease of use for consumers, settlement times and security and has witnessed good user adoption. Its modular API based architecture will enable development of innovative solutions for consumers and businesses. UPI is currently in its infancy stage and development of merchant centric UPI solutions will greatly increase the user adoption. UPI can help bring a large part of the population within the ambit of digital economy and can be a great tool for financial inclusion in India.
Mass Distribution in Space-Time and Conception about Space-Time-Mass Continuum  [PDF]
Rahul Singh
International Journal of Astronomy and Astrophysics (IJAA) , 2018, DOI: 10.4236/ijaa.2018.81007
Abstract: There is a relation between space and time, which is called space-time continuum. With the help of some mathematical equations, we can establish an alternative relation between space-time and mass, treating mass as a fifth dimension. There is the concept about mass being a property of any inertial or gravitational object in space. Mass can create distortion in space. As a result of that, space-time curvature will be bent towards the massive object.
Assessment of yield loss in cauliflower seed crop due to Alternaria blight
Indian Phytopathology , 2012,
Abstract: Alternaria blight caused by Alternaria brassicae (Berk.) Sacc. and A. brassicicola (Schw.) Wilts is responsible for poor seed quality, and yield losses in seed crop of Cauliflower (Brassica oleracea L. var. botrytis subvar. cauliflora). Yield loss due to the blight disease was studied in four cultivars viz., Pant Gobhi (PG) 2, PG 3, PG 4 (early maturing cultivars) and Pant-Subhra (a mid maturing cultivar). Highest seed yield losses (55.93) were found in mid maturing variety Pant Shubhra, inspite of being a variety giving highest curd productivity. Variety Pant Gobhi 4 gave highest seed yield (46.13) amongst the early maturing cultivars. The curd area infection is found directly proportional to seed yield losses in all the cultivars. The maximum loss (49.97%) in seed test weight was in cultivar PG2 at all the degree of pod area infection while minimum loss (9.69%) in seed test weight was found in Pant Subhra.
Approximate controllability and optimal control of impulsive fractional semilinear delay differential equations with non-local conditions
Lakshman Mahto,Syed Abbas
Mathematics , 2013,
Abstract: In this paper we study the approximate controllability and existence of optimal control of impulsive fractional semilinear delay differential equations with non-local conditions. We use Sadovskii's fixed point theorem, semigroup theory of linear operators and direct method for minimizing a functional to establish our results. At the end we give an example to illustrate our analytical findings.
Safety and efficacy of testosterone gel in the treatment of male hypogonadism
Kishore M Lakshman, Shehzad Basaria
Clinical Interventions in Aging , 2009, DOI: http://dx.doi.org/10.2147/CIA.S4466
Abstract: fety and efficacy of testosterone gel in the treatment of male hypogonadism Review (8751) Total Article Views Authors: Kishore M Lakshman, Shehzad Basaria Published Date October 2009 Volume 2009:4 Pages 397 - 412 DOI: http://dx.doi.org/10.2147/CIA.S4466 Kishore M Lakshman, Shehzad Basaria Section of Endocrinology, Diabetes, and Nutrition. Boston University School of Medicine, Boston Medical Center, Boston, MA, USA Abstract: Transdermal testosterone gels were first introduced in the US in 2000. Since then, they have emerged as a favorable mode of testosterone substitution. Serum testosterone levels reach a steady-state in the first 24 hours of application and remain in the normal range for the duration of the application. This pharmacokinetic profile is comparable to that of testosterone patch but superior to injectable testosterone esters that are associated with peaks and troughs with each dose. Testosterone gels are as efficacious as patches and injectable forms in their effects on sexual function and mood. Anticipated increases in prostate-specific antigen with testosterone therapy are not significantly different with testosterone gels, and the risk of polycythemia is lower than injectable modalities. Application site reactions, a major drawback of testosterone patches, occur less frequently with testosterone gels. However, inter-personal transfer is a concern if appropriate precautions are not taken. Superior tolerability and dose flexibility make testosterone gel highly desirable over other modalities of testosterone replacement. Androgel and Testim, the two currently available testosterone gel products in the US, have certain brandspecific properties that clinicians may consider prior to prescribing.
Lakshman Vijayashree,Mali Vishalkumar Jagdischchandra
Serbian Journal of Management , 2011,
Abstract: Previous research studies have demonstrated that internal/external locus of control impacts jobsatisfaction. The present study thus aims to analyze type of locus of control and its relation with jobsatisfaction. The study will be of great help for organization to understand and know what type oflocus of control their employees has and how it has an impact on job satisfaction.The objectives of this study were: 1- To identify the type of Locus of Control (i.e. Internal orExternal) present in Public Sector Units (PSU) in Bangalore and 2- To analyze the impact of differenttype of Locus of Control on job satisfaction of PSU Employees. Further hypothesis was also set tocheck the relationship between locus of control and job satisfaction. In addition, the relationshipbetween different demographic factors was also examined. The tool used for this study was LocoInventory. The concept of locus of control by Levenson (1972) was used to develop Loco Inventory(Locus of Control in Organization Inventory). The survey used a questionnaire, which had thirty fivestatements which highlights the factors that determine the locus of control and job satisfaction levelof the employees. The Ratio, ANOVA, and Correlation analysis were used as statistical techniquesfor analysis.The results indicate that there is a positive correlation between internal locus of control and jobsatisfaction as well as between External (other) locus of control and job satisfaction. And in case ofExternal (Chance) locus of control and job satisfaction there exists partial positive correlation. As perthis study Job satisfaction level among the employees is also good as the mean is 17, which is closerto maximum scale value of 25. As per ANOVA table there is a significant variance betweeninternality and age as well as between externality (chance) and age. There is no significantrelationship between internality and demographic factors like gender and education. There is nosignificant relationship between externality (others) and demographic factors like gender, age andeducation. There is no significant relationship between externality (chance) and demographic factorslike gender and education.
Employment of gene expression profiling to identify transcriptional regulators of hepatic stellate cells
Shimada Hideaki,Rajagopalan Lakshman E
Fibrogenesis & Tissue Repair , 2012, DOI: 10.1186/1755-1536-5-s1-s12
Abstract: Activated hepatic stellate cells (HSC) play a central role in scar formation that leads to liver fibrosis. The molecular mechanisms underlying this process are not fully understood. Microarray and bioinformatics analyses have proven to be useful in identifying transcription factors that regulate cellular processes such as cell differentiation. Using oligonucleotide microarrays, we performed transcriptional analyses of activated human HSC cultured on Matrigel-coated tissue culture dishes. Examination of microarray data following Matrigel-induced deactivation of HSC revealed a significant down-regulation of myocardin, an important transcriptional regulator in smooth and cardiac muscle development. Thus, gene expression profiling as well as functional assays of activated HSC have provided the first evidence of the involvement of myocardin in HSC activation.
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