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Search Results: 1 - 10 of 1035 matches for " Radha Iyer "
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The regular number of a graph
Ashwin Ganesan,Radha R. Iyer
Computer Science , 2011,
Abstract: Let $G$ be a simple undirected graph. The regular number of $G$ is defined to be the minimum number of subsets into which the edge set of $G$ can be partitioned so that the subgraph induced by each subset is regular. In this work, we obtain the regular number of some families of graphs and discuss some general bounds on this parameter. Also, some of the lower or upper bounds proved in \cite{Kulli:Janakiram:Iyer:2001} are shown here to hold with equality.
Copyright, digital media literacies and preservice teacher education
Michael Dezuanni,Cushla Kapitzke,Radha Iyer
Digital Culture & Education , 2010,
Abstract: This article considers copyright knowledge and skills as a new literacy that can be developed through the application of digital media literacy pedagogies. Digital media literacy is emerging from more established forms of media literacy that have existed in schools for several decades and have continued to change as the social and cultural practices around media technologies have changed. Changing requirements of copyright law present specific new challenges for media literacy education because the digitisation of media materials provides individuals with opportunities to appropriate and circulate culture in ways that were previously impossible. This article discusses a project in which a group of preservice media literacy educators were introduced to knowledge and skills required for the productive and informed use of different copyrights frameworks. The students’ written reflections and video production responses to a series of workshops about copyright are discussed, as are the opportunities and challenges provided by copyright education in preservice teacher education.
Borrelia burgdorferi Requires Glycerol for Maximum Fitness During The Tick Phase of the Enzootic Cycle
Christopher J. Pappas,Radha Iyer,Mary M. Petzke,Melissa J. Caimano,Justin D. Radolf,Ira Schwartz
PLOS Pathogens , 2011, DOI: 10.1371/journal.ppat.1002102
Abstract: Borrelia burgdorferi, the spirochetal agent of Lyme disease, is a vector-borne pathogen that cycles between a mammalian host and tick vector. This complex life cycle requires that the spirochete modulate its gene expression program to facilitate growth and maintenance in these diverse milieus. B. burgdorferi contains an operon that is predicted to encode proteins that would mediate the uptake and conversion of glycerol to dihydroxyacetone phosphate. Previous studies indicated that expression of the operon is elevated at 23°C and is repressed in the presence of the alternative sigma factor RpoS, suggesting that glycerol utilization may play an important role during the tick phase. This possibility was further explored in the current study by expression analysis and mutagenesis of glpD, a gene predicted to encode glycerol 3-phosphate dehydrogenase. Transcript levels for glpD were significantly lower in mouse joints relative to their levels in ticks. Expression of GlpD protein was repressed in an RpoS-dependent manner during growth of spirochetes within dialysis membrane chambers implanted in rat peritoneal cavities. In medium supplemented with glycerol as the principal carbohydrate, wild-type B. burgdorferi grew to a significantly higher cell density than glpD mutant spirochetes during growth in vitro at 25°C. glpD mutant spirochetes were fully infectious in mice by either needle or tick inoculation. In contrast, glpD mutants grew to significantly lower densities than wild-type B. burgdorferi in nymphal ticks and displayed a replication defect in feeding nymphs. The findings suggest that B. burgdorferi undergoes a switch in carbohydrate utilization during the mammal to tick transition. Further, the results demonstrate that the ability to utilize glycerol as a carbohydrate source for glycolysis during the tick phase of the infectious cycle is critical for maximal B. burgdorferi fitness.
3D Visualization of UMTS/WLAN Integration Using OPNET Modeler  [PDF]
Sankaranarayanan Radha Ramyah
Wireless Sensor Network (WSN) , 2012, DOI: 10.4236/wsn.2012.412040
Abstract: The primary design goal for this project is to interwork WLAN with UMTS and visualizing in 3D network, so that it can be utilized as an alternate radio access network for defense system. Simulations and modeling have become a very important part of the process when designing communication networks. Only a real network, with real hardware will provide real results. General Dynamics C4 Systems has been working collaboratively multiple routing protocol interaction. 3D Network Visualizer (3DNV) functionality lets you create three-dimensional animations based on topology information, node relationships, performance statistics, and terrain data. The OPNET Modeler is one of the most powerful simulation tools regarding communications. It is especially useful on R&D (research and development) areas for developers of communication devices and protocols. The network model must have a terrain database specified. The nodes to be animated must be mapped to specific shapes (called entities in 3DNV) using a 3DNV mapping library. Furthermore, a 3D visualization of the entire network has been developed, representing both real and simulated nodes, including effects on their communications. The other purpose of this paper is to evaluate different integration solutions and mobility schemes that provide best service and performance by using OPNET as simulation tool.
Cardiac Sarcolemmal Defects in Acute Myocarditis Due to Scorpion Envenoming Syndrome  [PDF]
K. Radha Krishna Murthy
World Journal of Cardiovascular Diseases (WJCD) , 2014, DOI: 10.4236/wjcd.2014.49054
Abstract:

Death due to scorpion envenoming syndrome is a common event in tropical and subtropical countries. Severe scorpion envenoming causes autonomic storm, massive release of catecholamines, counter-regulatory hormones, suppressed insulin/hyperinsulinemia, acute myocarditis, hyperglycemia, increased free fatty Acid levels, acute pancreatitis, disseminated intra-vascular coagulation, acute pulmonary oedema and death. Severe scorpion envenoming causes cardiac sarcolemmal defects displayed by alterations in Na+ - K+ ATPase, Mg++ ATPase and Ca2+ ATPase activities, inhibition of erythrocyte Na+ - K+ ATPase activities, hyperkalemia and may result in death. Based on our animal experiments in which insulin administration reversed the metabolic and ECG changes induced by scorpion envenoming and treating the poisonous scorpion sting victims with insulin, we consider that insulin has a primary metabolic role in preventing and reversing acute myocarditis, the cardiovascular, haemodynamic, and neurological manifestations and pulmonary oedema induced by scorpion envenoming. Administration of insulin-glucose infusion to scorpion sting victims appears to be the physiological basis for the control of the metabolic response when that has become a determinant to survival. Continuous infusion of regular crystalline insulin should be given at the rate of 0.3 U/g glucose and glucose at the rate of 0.1 g/kg body weight/hour, for 48 - 72 hours, with supplementation of potassium as needed and maintenance of fluid, electrolytes and acid-base balance. The observation of cardiac sarcolemmal defects and physiological basis of various patho-physiological mechanisms involved in the genesis of scorpion envenoming syndrome and its reversal (in the experimental animals and scorpion sting victims) by administration of insulin are reviewed.

Hypertension, Autonomic Storm, Increased Counter Regulatory Hormones and Suppressed Insulin in Acute Myocarditis in Scorpion Envenoming Syndrome  [PDF]
Kari Radha Krishna Murthy
World Journal of Cardiovascular Diseases (WJCD) , 2014, DOI: 10.4236/wjcd.2014.44027
Abstract: Death due to scorpion envenoming syndrome is a common event in many of the tropical and non-tropical counties. Initial transient hypertension is commonly observed in scorpion sting victims. Scorpion envenoming causes autonomic storm resulting in initial transient hypertension followed by hypotension, cold clammy skin, hypothermia, cardiovascular disturbances, acute myocarditis, sarcolemmal defects, pulmonary oedema, acute pancreatitis, disseminated intravascular coagulation (DIC), Adult respiratory distress syndrome (ARDS), and many other clinical manifestations. All these manifestations could be due to sudden increase in catecholamines, angiotensin II, glucagon, Cortisol and either due to suppressed insulin secretion or insulin resistance and death. The sudden increase of metabolic A in counter-regulatory hormones along with either suppressed insulin secretion/or insulin resistance results in glycogenolysis in liver, cardiac and skeletal muscles causing hyperglycemia and a sudden increase in free fatty acid levels. Free Fatty Acids increase the susceptibility of the ventricles to the disorganized electrical behavior, inhibit cardiac sarcolemmal Na+-K+ ATPase activity, increase the tendency to intravascular thrombus, increase myocardial oxygen consumption, interfere with tropomyosin-troponin activation of Actin-Myosin coupling, show detergent effects on cell membranes and they could alter the stabilization of lysosomal membranes and probably become toxic to the myocardium. Based on our animal experiments in which insulin administration reversed the metabolic and ECG changes induced by scorpion envenoming and treating the poisonous scorpion sting victims with insulin, we consider that insulin has a primary metabolic role in preventing, counter-acting and reversing all the deleterious effects of FFA by inhibiting the catecholamine induced by lipolysis, and increasing intra-cellular K+, facilitating glucose transport to the myocardium and glucose metabolism through different pathways. Administration of insulin-glucose infusion to scorpion sting victims appears to be the physiological basis for the control of the metabolic response when that has become a determinant to survival. Treatment using continuous infusion of regular crystalline insulin should be given at the rate of 0.3 U/g glucose and glucose at the rate of 0.1 g/kg body weight/hour, for 48 - 72 hours, with supplementation of potassium as needed and maintenance of fluid, electrolytes and acid-base balance.
Identification of water-borne bacterial isolates for potential remediation of organophosphate contamination  [PDF]
Rupa Iyer, Brian Iken
Advances in Biological Chemistry (ABC) , 2013, DOI: 10.4236/abc.2013.31018
Abstract:

Three water-borne bacterial isolates were collected from the Houston metropolitan area. Each isolate was capable of growing upon carbon limited media inoculated with the organophosphorus (OP) compound paraoxon. All isolates were able to efficiently metabolize paraoxon and, to a lesser degree, methyl parathion to p-nitrophenol. 16S rDNA genome sequencing with universal bacterial primers identified the isolates as species belonging to the genera Aeromonas, Steno- trophomonas, or Exiguobacterium. All screened isolates harbor organophosphorus degradation (opd) genes that are approximately 99% similar over approximately 660 base pairs sequenced to one first isolated from Sphingobium fuliginis ATCC 27551 (formerly Flavobacterium sp. ATCC 27551). Additionally, two isolates KKWT11, identified as a putative Senotro- phomonas maltophilia, and KKBO11, identified as a putative Exiguobacterium indicum, were found to possess genomic DNA that closely matched a metallo- beta-lactamase that has been reported to function as a methyl parathion degradation (mpd) gene suggesting that both of these strains are prime candidates for wastewater remediation of a broad range of OP compounds.

Chern-Simons classes of flat connections on supermanifolds
JN Iyer,Un Iyer
Mathematics , 2007,
Abstract: In this note we define Chern-Simons classes of a superconnection $D+L$ on a complex supervector bundle $E$ such that $D$ is flat and preserves the grading, and $L$ is an odd endomorphism of $E$ on a supermanifold. As an application we obtain a definition of Chern-Simons classes of a (not necessarily flat) morphism between flat vector bundles on a smooth manifold. We extend Reznikov's theorem on triviality of these classes when the manifold is a compact K\"ahler manifold or a smooth complex quasi--projective variety, in degrees > 1.
Life style of patient before and after diagnosis of hypertension in Kathmandu  [PDF]
Radha Acharya, Hom Nath Chalise
Health (Health) , 2011, DOI: 10.4236/health.2011.38081
Abstract: Hypertension is an important public health-challenge in the developing and the developed world alike. However, hospital-based studies on cardiovascular diseases including hypertension in a developing country like Nepal have been limited. Objective: The objective of the present study was to determine the life style of patients before and after diagnosis of hypertension. Methods: A total of 100 adult hypertensive patients over 30 years of age who were attending in medical out patients department within 6 month to 2 years after first diagnosis of hypertension in Shahid Gangalal National Heart Centre and Tribhuvan University Teaching Hospital, in Kathmandu, Nepal, in April 2009, using a descriptive research design. The data was collected by interview using a questionnaire consisting of a combination of structured and semistructured questions. The data was analyzed by using SPSS 11.5 version. Results: This study found the respondents’ knowledge regarding hypertension was poor. Regarding life style of hypertensive patients, majorities (90%) of them were non-vegetarian before diagnosis but after diagnosis of hypertension the percentage of non-vegetarian was reduced by 10%. Similarly, the reduction in consumption of meat, eggs, ghee and oil (mustard, sunflower) by hypertensive patients was statistically significant difference (p = 0.000) after the diagnosis of hypertension. Regarding soyabean oil consumption, additional salty food and amount of salt intake there was no statistical significant difference before and after the diagnosis of hypertension. Likewise, physical exercise and stress reduction activities performed by hypertensive patients and change in drinking alcohol and smoking was found to be statistically significant difference (p = 0.000) after the diagnosis of hypertension. Conclusion: The adverse consequences of hypertension can be reduced by modifying the life style. Therefore more focus should be given in increasing the awareness about hypertension by developing information, education and communication materials on hypertension and setting up hypertensive counseling clinic in each hospitals.
Knowledge regarding preventive measures of heart disease among the adult population in Kathmandu  [PDF]
Radha Acharya Pandey, Ismita Khadka
Health (Health) , 2012, DOI: 10.4236/health.2012.49094
Abstract: Heart disease is the leading cause of death globally. Prevention is the most effective way of combating its epidemic in the resource poor nations. Knowledge on preventive measures of heart diseases has been identified as a prerequisite for change in behavior. This study was conducted with the purpose of identifying the knowledge on heart disease and its prevention among the adults population residing in Dadhikot VDC of Bhaktapur district by interviewing house to house survey. A total of 405 respondents who met the eligible criteria were systematically sampled and interviewed face to face for the study. A pretested Nepali version semi-structured interview schedule was used to collect data from adults. The duration of the study was one month i.e. June, 2011. Among total respondents, 57.8 percent had adequate knowledge on heart disease. Only less than half (46.9%) knew age as non-modifiable risk factor for heart disease followed by hereditary (39.8%) and sex (13.8%). Regarding modifiable risk factors, the most cited response was fatty food consumption (72.6%) followed by smoking (70.4%), stress (63.7%), physical inactivity (61.7%), hypertension (59%), obesity (58.8%), high cholesterol diet (36.5%) and diabetes (30.1%). Most of the respondents (57.8%) knew dyspnea during exertion as symptom of heart disease followed by chest pain (24%). Majority of respondents (80.7%) cited decreasing fatty diet as preventive measure of heart disease following daily exercise (75.6%), eating vegetables and fruits (71.6%), keeping blood pressure under control (59%) and keeping diabetes under control (33.8%) respectively. Knowledge was significantly associated with age, gender, education level and family history of heart disease. Conclusion: The findings concluded that significant percentage (42.2%) of respondents had inadequate knowledge on heart disease. The findings also highlighted the lack of knowledge on high cholesterol diet and diabetes as modifiable risk factors for heart disease i.e. 36.5% and 30.1% respectively. So it is recommended that awareness raising programs could be beneficial on prevention of heart disease is correcting in the deficient areas of knowledge regarding preventive measures of heart disease.
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