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Search Results: 1 - 10 of 120962 matches for " Rachel T. Lebese "
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Experiences of family members caring for tuberculosis patients at home at Vhembe district of the Limpopo Province
Joyce T. Sukumani,Rachel T. Lebese,Lunic B. Khoza,Patrone R. Risenga
Curationis , 2012, DOI: 10.4102/curationis.v35i1.54
Abstract: Tuberculosis (TB) is a potentially serious infectious disease which enters the body by inhalation and usually affects the lungs. TB is ranked amongst the leading infectious diseases worldwide, and in South Africa (SA) it has become an epidemic, because of its high prevalence. There are multiple factors that were found to attribute to the existence and spread of this disease. The purpose of this study was to explore and describe experiences of family members caring for TB patients at home, in the Vhembe District of the Limpopo Province. The study was qualitative, explorative, descriptive, phenomenological and contextual in nature. The population group selected for the study all comprised of family members caring for tuberculosis patients at home in Tshifulanani village. A purposive sampling method was applied in the study. Data were collected through semi-structured interviews guided by three questions. Tech’s eight steps of data analysis were followed. Measures to ensure trustworthiness and ethical issues were observed. The results of the study revealed that family members experienced difficulties when they care for TB patients at home. These difficulties included providing food, attending to hygiene needs, the lack of equipment, financial constraints as well as physical and psychological exhaustion. Recommendations were made concerning the provision food, attending to hygiene needs, assisting in the administration of medication, nursing practice and policy making. How to cite this article: Sukumani, J.T., Lebese, RT., Khoza, L.B. & Risenga, P.R., 2012, ‘Experiences of family members caring for tuberculosis patients at home at Vhembe district of the Limpopo Province’,Curationis 35(1), Art. #54,8 pages. http://dx.doi.org/10.4102/curationis.v35i1.54
Factors influencing the uptake of contraception services by Vatsonga adolescents in rural communities of Vhembe District in Limpopo Province, South Africa
Rachel T. Lebese,Sonto M. Maputle,Dorah U. Ramathuba,Lunic B. Khoza
Health SA Gesondheid , 2013,
Abstract: The aim of the study was to determine the factors that influence the uptake of contraception services by adolescents in the Vhembe district of Limpopo Province, South Africa. A qualitative research method which is explorative, descriptive and contextual in nature was used to investigate the phenomenon from the adolescents’ perspective. The target population comprised of adolescents residing in one of the six villages of Vhembe District. Data was collected through six focus group discussions until data saturation was achieved. Data was analysed using an open coding method. The findings revealed that adolescents are aware of the availability of contraceptive services. However, they lack a comprehensive knowledge about contraception and contraceptives, which led to negative attitudes towards using the services. Cultural health beliefs and attitudes were also identified as a barrier to the uptake and use of contraceptives. Recommendations were made on interventions to increase the uptake of contraception services amongst adolescents.
Sexual health dialogue between parents and teenagers: An imperative in the HIV/AIDS era
R. T. Lebese,M. Davhana – Maselesele,C. L. Obi
Curationis , 2011, DOI: 10.4102/curationis.v33i3.5
Abstract: Societies are reluctant to openly confront issues of sexuality, and this reluctance forms a barrier of communication between parents and teenagers and even between sexual partners (Wulf, 2004:2). This reluctance promotes the presence of misconceptions about sexual health, sexual risks and its consequences. Poor dialogue about sexual health between parents and teenagers is one of the contributory factors of high teenage pregnancy and sexually transmitted infection (STI) rates including HIV and AIDS. The purpose of this study was to explore and describe how dialogue about sexual health between teenagers and parents is conducted and to use the information gathered as a basis for making recommendations for improvement. A qualitative study of an explorative, descriptive and contextual nature was used. The researcher used the main question as a point of departure and more questions emanated from the discussions. There were 42 informants involved in the study, of which 4 were males and 38 were females. A purposive sampling method was used to collect data through in depth individual interviews and focus group discussions. The researcher strived to adhere to the principle of trustworthiness by adopting Guba’s model (in Krefting, 1991: 217). Tech’s method (Creswell, 1994: 154-55) was used to analyse the data and an independent coder was used. The results indicate that there is minimal if not absent dialogue about sexual health between teenagers and parents. Culture was identified as a major challenge to sexual health dialogue between teenagers and parents. Recommendations to enhance dialogue were made.
Self-Assembly of Colloidosome Shells on Drug-Containing Hydrogels  [PDF]
Rachel T. Rosenberg, Nily Dan
Journal of Biomaterials and Nanobiotechnology (JBNB) , 2011, DOI: 10.4236/jbnb.2011.21001
Abstract: Colloidosomes are composed of an aqueous or hydrogel corethat is coated by a semi-permeable colloidal shell. The properties of the shell can be varied to control the rate of release of encapsulated components such as drugs. Specifi-cally, the pores formed between the colloidal particles suppress transport of large components, while allowing diffusion of smaller ones. Self-assembly of colloidal particles on hydrogel films is a convenient method forcolloidosome synthesis, but to date little is known regarding the effect (if any) of the encapsulated drug on the shell packing density. In this paper we examined self-assembly of colloidal shells on alginate films containing four model drugs: aspirin, caffeine, theophylline and theobromine. We find that the packing density in the colloidal shells is low for all drugs, and ranges between 0.16 and 0.3. There is no clear correlation between drug properties (in particular, water solubility) and the packing density of the self-assembled colloidal shell.
The chlamydial functional homolog of KsgA confers kasugamycin sensitivity to Chlamydia trachomatis and impacts bacterial fitness
Rachel Binet, Anthony T Maurelli
BMC Microbiology , 2009, DOI: 10.1186/1471-2180-9-279
Abstract: Lack of the dimethylated adenosines following ksgA inactivation confers resistance to kasugamycin (KSM) in E. coli. Expression of the C. trachomatis L2 KsgA ortholog restored KSM sensitivity to the E. coli ksgA mutant, suggesting that the chlamydial KsgA homolog has specific rRNA dimethylase activity. C. trachomatis growth was sensitive to KSM and we were able to isolate a KSM resistant mutant of C. trachomatis containing a frameshift mutation in ksgA, which led to the formation of a shorter protein with no activity. Growth of the C. trachomatis ksgA mutant was negatively affected in cell culture highlighting the importance of the methylase in the development of these obligate intracellular and as yet genetically intractable pathogens.The presence of a functional rRNA dimethylase enzyme belonging to the KsgA family in Chlamydia presents an excellent chemotherapeutic target with real potential. It also confirms the existence of S-adenosyl-methionine - dependent methylation reactions in Chlamydia raising the question of how these organisms acquire this cofactor.Ribosomes are complex macromolecular machines that are found in abundance in all cells that are actively making proteins. Two-thirds of the ribosome is composed of RNA molecules (rRNA) that share a high degree of conservation in primary sequence as well as in secondary and tertiary structural elements across kingdoms [1]. Numerous nucleotide modifications, mainly but not exclusively via methylation, are found on rRNAs but the functional importance of these post-transcriptional modifications remains unclear [2]. For example, the two adenosine residues in the loop of helix 45 near the 3'end of the small subunit rRNA (positions 1518 and 1519 of the 16S rRNA in the Escherichia coli numbering system) are universally conserved, and are dimethylated by a specific enzyme belonging to the rRNA adenine dimethylase family, which is represented by the E. coli KsgA protein [3]. While these enzymes are present in all three k
New developments in cognitive behavioral therapy as the first-line treatment of insomnia
Allison T Siebern, Rachel Manber
Psychology Research and Behavior Management , 2011, DOI: http://dx.doi.org/10.2147/PRBM.S10041
Abstract: evelopments in cognitive behavioral therapy as the first-line treatment of insomnia Review (6023) Total Article Views Authors: Allison T Siebern, Rachel Manber Published Date February 2011 Volume 2011:4 Pages 21 - 28 DOI: http://dx.doi.org/10.2147/PRBM.S10041 Allison T Siebern, Rachel Manber Sleep Medicine Center, Stanford University School of Medicine, Redwood City, California, USA Abstract: Insomnia is the most common sleep disorder. Psychological, behavioral, and biological factors are implicated in the development and maintenance of insomnia as a disorder, although the etiology of insomnia remains under investigation, as it is still not fully understood. Cognitive behavioral therapy for insomnia (CBTI) is a treatment for insomnia that is grounded in the science of behavior change, psychological theories, and the science of sleep. There is strong empirical evidence that CBTI is effective. Recognition of CBTI as the first-line treatment for chronic insomnia (National Institutes of Health consensus, British Medical Association) was based largely on evidence of its efficacy in primary insomnia. The aim of this article is to provide background information and review recent developments in CBTI, focusing on three domains: promising data on the use of CBTI when insomnia is experienced in the presence of comorbid conditions, new data on the use of CBTI as maintenance therapy, and emerging data on the delivery of CBTI through the use of technology and in primary care settings.
New developments in cognitive behavioral therapy as the first-line treatment of insomnia
Allison T Siebern,Rachel Manber
Psychology Research and Behavior Management , 2011,
Abstract: Allison T Siebern, Rachel ManberSleep Medicine Center, Stanford University School of Medicine, Redwood City, California, USAAbstract: Insomnia is the most common sleep disorder. Psychological, behavioral, and biological factors are implicated in the development and maintenance of insomnia as a disorder, although the etiology of insomnia remains under investigation, as it is still not fully understood. Cognitive behavioral therapy for insomnia (CBTI) is a treatment for insomnia that is grounded in the science of behavior change, psychological theories, and the science of sleep. There is strong empirical evidence that CBTI is effective. Recognition of CBTI as the first-line treatment for chronic insomnia (National Institutes of Health consensus, British Medical Association) was based largely on evidence of its efficacy in primary insomnia. The aim of this article is to provide background information and review recent developments in CBTI, focusing on three domains: promising data on the use of CBTI when insomnia is experienced in the presence of comorbid conditions, new data on the use of CBTI as maintenance therapy, and emerging data on the delivery of CBTI through the use of technology and in primary care settings.Keywords: insomnia, CBTI, nonpharmacological treatment
Density and Decision-Making: Findings from an Online Survey
Christopher T. Boyko,Rachel Cooper
Sustainability , 2013, DOI: 10.3390/su5104502
Abstract: In many countries, policymakers have used urban densification strategies in an effort to create more sustainable cities. However, spatial density as a concept remains unclear and complex. Little information exists about how density is considered by decision makers, including the different kinds of density and the wider political and economic context in which decisions are made: who makes density decisions, when they make those decisions and what they use to make decisions. To that end, the authors created an online survey to investigate the above issues. One hundred and twenty-nine respondents from the fields of architecture, planning, urban design and engineering answered a 26-item survey over a 3-month period. Findings suggest that decision makers consider more than just population and dwelling density and that city design, planning and policy need to address these other kinds of density. Moreover, the professions making many of the density decisions are not, necessarily, the ones that should be making the decisions; nor are they making decisions early enough. Policymakers also need to be more cognisant of the multi-scalar dimensions of density when creating policy. Finally, more needs to be done in universities to ensure that built environment students receive a broader skillset, particularly in terms of engaging with communities.
Teenagers’ experiences of sexual health dialogue in the rural villages of the Vhembe District, Limpopo Province
Lebese R. Tsakani,Mashudu Davhana- Maselesele,Larry C. Obi
Health SA Gesondheid , 2011, DOI: 10.4102/hsag.v16i1.502
Abstract: Dialogue with teenagers about sexual health is of global concern, as it is found mostly to be minimal, if not absent. This limitation is influenced by the cultural values, beliefs and norms of teenagers. To a great extent, culture influences which and how sexual health issues can be discussed between teenagers and adults. The purpose of this study was to explore and describe teenagers’ experiences of sexual health dialogue in the rural areas of the Vhembe district in Limpopo province, South Africa. A qualitative, explorative, descriptive and contextual research approach was used. Data were collected by means of in-depth, individual interviews and focus-group discussions. A purposive sampling method was used to select the 57 participating teenagers, based on criteria that were set. The findings of the study indicated that there was minimal dialogue between adults and teenagers about sexual health. Most teenagers reported that they learned about issues related to sexual health from friends, the media, initiation schools and relatives who, most often, were aunts. It was also noted with concern that the teenagers always equated sexual health to the act of intercourse and that no attention was paid to other aspects of sexual health. Recommendations to improve the current situation were made. Opsomming Dialoog met tienerjariges rakende seksuele gesondheid is ’n wêreldwye probleem omdat daar gevind is dat dit meestal minimaal is of glad nie plaasvind nie. Hierdie beperking word be nvloed deur die tienerjariges se kulturele waardes, oortuigings en norme. Kultuur be nvloed in ’n groot mate watter seksuele gesondheidsake tussen tienerjariges en volwassenes bespreek kan word, en hoe dit gedoen kan word. Die doel van hierdie studie was om tienerjariges se ondervindings van seksuele gesondheidsdialoog in die landelike gebiede van die Vhembedistrik in die Limpopo-provinsie van Suid-Afrika te ondersoek en te bespreek. ’n Kwalitatiewe,ondersoekende, beskrywende en kontekstuele navorsingsbenadering is gevolg.Data is versamel deur middel van grondige individuele onderhoude en fokusgroep-besprekings.’n Doelbewuste steekproefmetode is gebruik om die 57 deelnemende tienerjariges op grond van bepaalde kriteria te selekteer.Die bevindings van die studie het aangedui dat daar minimale dialoog oor seksuele gesondheid tussen tienerjariges en volwassenes is. Die meeste tienerjariges het gerapporteer dat hulle by vriende, die media, inisiasieskole en familielede, meestal ’n tante, van seksuele gesondheid geleer het. Daar is met kommer opgemerk dat tienerjariges seksuele gesondheid
Estudo reológico da gelifica??o induzida pelo calor de proteínas do soro do leite e dos géis resultantes sob condi??es variadas de pH
Andrade, Cristina T.;Nasser, Rachel O.;
Ciência e Tecnologia de Alimentos , 2005, DOI: 10.1590/S0101-20612005000200023
Abstract: rheological measurements have been carried out in a controlled stress and strain rheometer on a whey proteins concentrate (wpc) at 10% (w/w) in water and at different ph conditions (ph 4.0, 4.6 and 7.0). the heat-induced gelation process was investigated, as well as the viscoelastic properties of the gels formed at 80°c and those formed after decreasing the temperature to 20°c. the results indicated that, in the presence of significant contents of salts from the whey sample, the concentration used in the experiments was sufficient for the formation of macroscopic gels, and that the ph exerts an important role on the formation and on the structural nature of the gels.
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