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Search Results: 1 - 10 of 3410 matches for " ROMAN ?KULEC "
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Targeting out-of-hospital cardiac arrest: the effect of heparin administered during cardiopulmonary resuscitation (T-ARREST)
JIRí KNOR,MILANA POKORNá,ROMANKULEC,JIRí MáLEK
Signa Vitae , 2011,
Abstract: Introduction. Heparin administration during cardiopulmonary resuscitation (CPR) may prevent activation of coagulation after successful resuscitation for out-of-hospital cardiac arrest (OHCA). We hypothesize that such an approach is not associated with an increased rate of bleeding, but it has not been evaluated. We performed a pilot randomized clinical study assessing the safety of intra-arrest heparin administration in OHCA patients with suspected acute myocardial infarction (AMI) and its impact on their prognosis. Materials and Methods. OHCA patients were randomized during CPR to 10 000 units of intra-arrest intravenous heparin (Group H) or to treatment without heparin (Group C). The occurrence of major bleeding and the presence of a favourable neurological result 3 months after OHCA, were analyzed. Results. Out of 88 randomized patients, AMI was subsequently confirmed in 63 of them (71.6 %). There were 30 patients in group H and 33 in group C. No major bleeding event was observed in either group. Return of spontaneous circulation (ROSC, Group H: 40.0%, Group C: 45.4%, p=0.662) and a good neurological result 3 months after OHCA (Group H: 6.7 %, Group C: 9.1 %, p=0.921) did not differ between groups. Conclusions. Intravenous administration of 10 000 units of heparin during CPR for OHCA in patients with supposed AMI was safe. We did not find any improvement in prognosis for our sample of limited size. Though the procedure proved safe, we recommend postponing the administration of heparin until ROSC, assessment of clinical state and recording of a twelve-lead ECG.
Pre-hospital cooling of patients following cardiac arrest is effective using even low volumes of cold saline
Romankulec, Anatolij Truhlá?, Jana ?eblová, Pavel Dostál, Vladimír ?erny
Critical Care , 2010, DOI: 10.1186/cc9386
Abstract: We performed a prospective observational study with a retrospective control group. A total of 40 patients were cooled by an intravenous administration of 15-20 ml/kg of 4°C cold normal saline during transport to the hospital (TH group). The pre-hospital decrease of tympanic temperature (TT) was analyzed as the primary endpoint. Patients in the control group did not undergo any pre-hospital cooling.In the TH group, administration of 12.6 ± 6.4 ml/kg of 4°C cold normal saline was followed by a pre-hospital decrease of TT of 1.4 ± 0.8°C in 42.8 ± 19.6 min (p < 0.001). The most effective cooling was associated with a transport time duration of 38-60 min and with an infusion of 17 ml/kg of cold saline. In the TH group, a trend toward a reduced need for catecholamines during transport was detected (35.0 vs. 52.5%, p = 0.115). There were no differences in demographic variables, comorbidities, parameters of the cardiopulmonary resuscitation and in other post-resuscitation characteristics. The coupling of pre-hospital cooling with subsequent in-hospital TH predicted a favorable neurological outcome at hospital discharge (OR 4.1, CI95% 1.1-18.2, p = 0.046).Pre-hospital induction of TH by the rapid intravenous administration of cold normal saline has been shown to be efficient even with a lower dose of coolant than reported in previous studies. This dose can be associated with a favorable impact on circulatory stability early after the return of spontaneous circulation and, when coupled with in-hospital continuation of cooling, can potentially improve the prognosis of patients.ClinicalTrials (NCT): NCT00915421Therapeutic mild hypothermia (TH) has become a routine part of in-hospital post-resuscitation support. It has been recommended that the target therapeutic temperature be reached as soon as possible [1]. Thus, in successfully resuscitated out-of-hospital cardiac arrest (OHCA) patients, pre-hospital initiation of cooling appears to be a method of choice. A few studies demon
Mathematical Model of Embodied Symbols: Cognition and Perceptual Symbol System  [PDF]
Leonid Perlovsky, Roman Ilin
Journal of Behavioral and Brain Science (JBBS) , 2012, DOI: 10.4236/jbbs.2012.22024
Abstract: A mathematical model of perceptual symbol system is developed. This development requires new mathematical methods of dynamic logic (DL), which have overcome limitations of classical artificial intelligence and connectionist approaches. The paper discusses these past limitations, relates them to combinatorial complexity (exponential explosion) of algorithms in the past, and relates it further to the static nature of classical logic. DL is a process-logic; its salient property is evolution of vague representations into crisp. We first consider one aspect of PSS: situation learning from object perceptions. Next DL is related to PSS mechanisms of concepts, simulators, grounding, embodiment, productiveity, binding, recursion, and to the mechanisms relating embodied-grounded and amodal symbols. We discuss DL capability for modeling cognition on multiple levels of abstraction. PSS is extended toward interaction between cognition and language. Experimental predictions of the theory are discussed. They might influence experimental psychology and impact future theoretical developments in cognitive science, including knowledge representation, and mechanisms of interaction between perception, cognition, and language. All mathematical equations are also discussed conceptually, so mathematical understanding is not required. Experimental evidence for DL and PSS in brain imaging is discussed as well as future research directions.
Fractal Parametric Oscillator as a Model of a Nonlinear Oscillation System in Natural Mediums  [PDF]
Roman I. Parovik
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2013, DOI: 10.4236/ijcns.2013.63016
Abstract:

The paper presents a model of fractal parametric oscillator. Showing that the solution of such a model exists and is unique. A study of the solution with the aid of diagrams Stratton-Ince. The regions of instability, which can occur parametric resonance. It is suggested that this solution can be any signal, including acoustic.

Working Time Reductions and Labour Force Participation in Unemployment Contexts: A Note  [PDF]
Angel Martin-Roman
Theoretical Economics Letters (TEL) , 2014, DOI: 10.4236/tel.2014.43025
Abstract: Work-sharing measures aim to reduce unemployment. When politicians are more interested in fostering this kind of measures is when the official unemployment rate published in statistics rises. There is already an important body of research addressing this issue, but it has mainly focused on the labour demand side. Nevertheless, it must not be forgotten that unemployment is determined both by demand and supply. The neoclassical model of labour supply predicts that a reduction of standard working hours encourages labour market participation. In this paper we show that this unambiguous result vanishes precisely when high unemployment makes that search transaction costs cannot be considered negligible.
Analytical Modeling of Vibration of Micropolar Plates  [PDF]
Lev Steinberg, Roman Kvasov
Applied Mathematics (AM) , 2015, DOI: 10.4236/am.2015.65077
Abstract: This paper presents an extension of mathematical static model to dynamic problems of micropolar elastic plates, recently developed by the authors. The dynamic model is based on the generalization of Hellinger-Prange-Reissner (HPR) variational principle for the linearized micropolar (Cosserat) elastodynamics. The vibration model incorporates high accuracy assumptions of the micropolar plate deformation. The computations predict additional natural frequencies, related with the material microstructure. These results are consistent with the size-effect principle known from the micropolar plate deformation. The classic Mindlin-Reissner plate resonance frequencies appear as a limiting case for homogeneous materials with no microstructure.
The Explanation of the Michelson-Morley Experiment Results by Means Universal Frame of Reference  [PDF]
Karol Szostek, Roman Szostek
Journal of Modern Physics (JMP) , 2017, DOI: 10.4236/jmp.2017.811110
Abstract: It is commonly thought that the Michelson-Morley experiment from 1887 and Kennedy-Thorndike experiment from 1932 demonstrated that the universal frame of reference (ether) does not exist and that the velocity of light in vacuum is absolutely constant. The analysis of this experiment led to the creation of the Special Theory of Relativity (STR). The article explains why Michelson-Morley and Kennedy-Thorndike experiments could not detect the universal frame of reference. In this article, a different transformation of time and position than the Lorentz transformation is derived on the basis of the geometric analysis of the Michelson-Morley and Kennedy-Thorndike experiments. The transformation is derived based on the assumption that the universal frame of reference (UFR) exists. UFR is a frame of reference in which the velocity of light is constant in every direction. In inertial frames of reference moving in the UFR, the velocity of light may be different. The article has derived the formula for relative speed and patterns for the maximum and minimum speed of light that can be measured in the inertial system. Finally, the anisotropy of the microwave background radiation has been explained by using the presented theory. According to the body kinematics model presented in this article, anisotropy of cosmic microwave background is the Doppler effect for observer moving in the UFR.
Reporte de caso y serie de casos: una aproximación para el pregrado
Franco Romaní Romaní
CIMEL. Ciencia e Investigación Médica Estudiantil Latinoamericana , 2010,
Abstract: La frecuencia de publicación de reportes y series de casos se ha incrementado con el transcurrir del tiempo. El reporte de un caso es la publicación biomédica que hace un reporte detallado de síntomas, signos, resultados de estudios auxiliares, tratamiento, complicaciones del tratamiento y seguimiento de un paciente individual, mientras que una serie de casos reporta entre 2 a 10 casos con alguna característica semejante que los vuelve agrupables. Los reportes de caso no permiten establecer causalidad y han ido perdiendo lugar en un cada vez mayor número de revistas por: su bajo rigor científico o por su bajo nivel de aplicación general en la práctica médica. Entre los criterios para que un caso sea evaluable se necesita que el caso sea una condición o enfermedad nueva, condición rara, infrecuente o poco comunicada, presentación inusual de enfermedad común o poco frecuente, entre otros. Cada reporte de caso presenta una condición única que tiene un valor educativo para el lector y que sirve para el planteamiento de hipótesis o la aparición de nuevas inquietudes que posteriormente puedan sean estudiadas mediante métodos más complejos.
Risk and Uncertainty in Anesthesia  [PDF]
Roman Pohorecki,Gary E. Hill
Open Journal of Anesthesiology (OJAnes) , 2013, DOI: 10.4236/ojanes.2013.37072
Abstract: This article discusses risk and uncertainty, both stochastic and epistemic, as it applies to anesthesia. It shows the difficulty in quantifying risk of individual case and the somewhat arbitrary and even incorrect and naive assignment of risk in individual patient care management. Effective and honest communication remains at the core of physician-patient relationship in discussing, evaluating and managing the individual case for optimum outcome as well as patients’ and their families' satisfaction and understanding.
Risk and Uncertainty in Anesthesia  [PDF]
Roman Pohorecki, Gary E. Hill
Open Journal of Anesthesiology (OJAnes) , 2013, DOI: 10.4236/ojanes.2013.37072
Abstract:

This article discusses risk and uncertainty, both stochastic and epistemic, as it applies to anesthesia. It shows the difficulty in quantifying risk of individual case and the somewhat arbitrary and even incorrect and naive assignment of risk in individual patient care management. Effective and honest communication remains at the core of physician-patient relationship in discussing, evaluating and managing the individual case for optimum outcome as well as patients’ and their families' satisfaction and understanding.

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