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Search Results: 1 - 10 of 392555 matches for " R. C. Sanghvi "
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Portfolio Management: Stock Ranking by Multiple Attribute Decision Making Methods  [PDF]
Haresh V. Dedania, Vipul R. Shah, Rajesh C. Sanghvi
Technology and Investment (TI) , 2015, DOI: 10.4236/ti.2015.64016
Abstract: An investor would like to build a balanced portfolio with stocks representing different sectors. Several researchers have attempted the portfolio selection problem by different methods. Many of these methods consider companies of different sectors together. However, it can be argued that the attributes affecting the company’s growth vary for different sectors. Therefore, it is advisable to compare a company with the companies of the same sector. There are many options for the selection of a stock from a particular sector. A stock ranking method is proposed by using MADM methods based on overall performance under a stochastic environment. Of many MADM methods, SAW, AHP, TOPSIS, and VIKOR are applied. Usually, Euclidean distances (2-norm) are considered in the implementation of TOPSIS and VIKOR methods. In this work, this norm is generalized to p-norm, where p > 1. The model is tested for 13 companies in the field of Information Technology sector (IT) listed on National Stock Exchange in India and 13 criteria as performance indicators of a company. A MATLAB GUI system is developed and the results are obtained for several values of p in case of TOPSIS and VIKOR methods besides other methods. As the result indicates, the ordering is not much affected by different values of p in certain range. Moreover, higher values of p have adverse effect on the ordering. The proposed model is able to provide better information on the overall performance of a particular stock in comparison with its peers. The results obtained by various methods clearly separate good companies from inferior companies though the exact ordering slightly differs.
Mycobacterium fortuitum keratitis
Sanghvi C
Indian Journal of Medical Microbiology , 2007,
Abstract: We report a case of mycobacterial keratitis characterized by apparently spontaneous onset, delayed diagnosis, and eventually necessitating evisceration inspite of systemic antibiotics and repeated corneal grafts.
Multi-Objective Optimization of Two-Stage Helical Gear Train Using NSGA-II
R. C. Sanghvi,A. S. Vashi,H. P. Patolia,R. G. Jivani
Journal of Optimization , 2014, DOI: 10.1155/2014/670297
Abstract: Gears not only transmit the motion and power satisfactorily but also can do so with uniform motion. The design of gears requires an iterative approach to optimize the design parameters that take care of kinematics aspects as well as strength aspects. Moreover, the choice of materials available for gears is limited. Owing to the complex combinations of the above facts, manual design of gears is complicated and time consuming. In this paper, the volume and load carrying capacity are optimized. Three different methodologies (i) MATLAB optimization toolbox, (ii) genetic algorithm (GA), and (iii) multiobjective optimization (NSGA-II) technique are used to solve the problem. In the first two methods, volume is minimized in the first step and then the load carrying capacities of both shafts are calculated. In the third method, the problem is treated as a multiobjective problem. For the optimization purpose, face width, module, and number of teeth are taken as design variables. Constraints are imposed on bending strength, surface fatigue strength, and interference. It is apparent from the comparison of results that the result obtained by NSGA-II is more superior than the results obtained by other methods in terms of both objectives. 1. Introduction Designing a new product consists of several parameters and phases, which differ according to the depth of design, input data, design strategy, procedures, and results. Mechanical design includes an optimization process in which designers always consider certain objectives such as strength, deflection, weight, wear, and corrosion depending on the requirements. However, design optimization for a complete mechanical assembly leads to a complicated objective function with a large number of design variables. So it is a better practice to apply optimization techniques for individual components or intermediate assemblies than a complete assembly. For example, in an automobile power transmission system, optimization of gearbox is computationally and mathematically simpler than the optimization of complete system. The preliminary design optimization of two-stage helical gear train has been a subject of considerable interest, since many high-performance power transmission applications require high-performance gear train. A traditional gear design involves computations based on tooth bending strength, tooth surface durability, tooth surface fatigue, interference, efficiency, and so forth. Gear design involves empirical formulas, different graphs and tables, which lead to a complicated design. Manual design is very difficult
A Re-Examination of Global Suppression of RNA Interference by HIV-1
Viraj R. Sanghvi,Laura F. Steel
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0017246
Abstract: The nature of the interaction between replicating HIV-1 and the cellular RNAi pathway has been controversial, but it is clear that it can be complex and multifaceted. It has been proposed that the interaction is bi-directional, whereby cellular silencing pathways can restrict HIV-1 replication, and in turn, HIV-1 can suppress silencing pathways. Overall suppression of RNAi has been suggested to occur via direct binding and inhibition of Dicer by the HIV-1 Tat protein or through sequestration of TRBP, a Dicer co-factor, by the structured TAR element of HIV-1 transcripts. The role of Tat as an inhibitor of Dicer has been questioned and our results support and extend the conclusion that Tat does not inhibit RNAi that is mediated by either exogenous or endogenous miRNAs. Similarly, we find no suppression of silencing pathways in cells with replicating virus, suggesting that viral products such as the TAR RNA elements also do not reduce the efficacy of cellular RNA silencing. However, knockdown of Dicer does allow increased viral replication and this occurs at a post-transcriptional level. These results support the idea that although individual miRNAs can act to restrict HIV-1 replication, the virus does not counter these effects through a global suppression of RNAi synthesis or processing.
Recent advances in imaging of brain tumors
Sanghvi D
Indian Journal of Cancer , 2009,
Abstract: The recent advances in brain tumor imaging offer unique anatomical as well as pathophysiological information that provides new insights on brain tumors, directed at facilitating therapeutic decisions and providing information regarding prognosis. This information is presently utilized in clinical practice for initial diagnosis and noninvasive, preoperative grading of tumors, biopsy planning, surgery, and radiation portal planning, as well as, prognostication. The newer advances described in this review include magnetic resonance (MR) diffusion and diffusion tensor imaging with tractography, perfusion imaging, MR spectroscopy, and functional imaging, using the blood oxygenation level dependent (BOLD) technique. Diffusion tensor MR imaging is the only noninvasive in vivo method for mapping white matter fiber tract trajectories in the human brain. In the current clinical practice, one of the most important indications of diffusion tensor imaging (DTI) is to study the relation of a tumor to the adjacent white matter tracts. Perfusion imaging with computed tomography (CT) and magnetic resonance imaging (MRI) is an exciting new radiological technique for noninvasive evaluation of cerebral hemodynamics, in certain definite clinical settings. Cerebral perfusion imaging describes the passage of blood through the brain′s vascular network. Perfusion imaging, especially with MRI has become an integral component of the complete radiological assessment of brain tumors. MR Spectroscopy (MSR) is the only noninvasive technique capable of measuring chemicals within the body. MRS distinguishes various metabolites on the basis of their slightly different chemical shifts or resonance frequencies. Functional MRI refers to the demonstration of brain function with neuroanatomic localization on a real-time basis. In patient care, functional MR imaging is primarily used in the preoperative evaluation of the relationship of a brain tumor with an eloquent cortex. The next decade will witness further sophistication of these techniques, with data available from larger studies. It is expected that imaging will continue to provide new and unique insights in neuro-oncology, which should hopefully contribute to the better management of patients with brain tumors.
Technical Review of peephole Technique in compiler to optimize intermediate code
Vaishali Sanghvi
American Journal of Engineering Research , 2013,
Abstract: Peephole optimization is a efficient and easy optimization technique used by compilers sometime called window or peephole is set of code that replace one sequence of instructions by another equivalent set of instructions, but shorter, faster. Peephole optimization is traditionally done through String pattern matching that is using regular expression. There are some the techniques of peephole optimization like constant folding, Strength reduction, null sequences, combine operation, algebraic laws, special case instructions, address mode operations.The peephole optimization is applied to several parts or section of program or code so main question is where to apply it before compilation, on the intermediate code or after compilation of the code .The aim of this dissertation to show the current state of peephole optimization and how apply it to the IR (Intermediate Representation) code that is generated by any programming language.
Postero-medial release in clubfoot - A retrospective study of causes of failures
Sanghvi A
Indian Journal of Orthopaedics , 2006,
Abstract: Introduction : Postero-medial release is the most common surgical procedure used to correct the deformity of clubfoot. It has been seen that despite a good correction immediately following the surgery, the long-term results are not satisfactory. Material and methods : A retrospective study was carried out in a total number 52 clubfeet in 36 patients treated by postero-medial release to assess the causes of failures. The mean duration after surgery was 5.1±1.2 years, mean age at operation was 1.1±0.5 years and mean age of patient at final follow up was 6.9±2.1 years. The results were plotted and compared with different variables. Results : The results were successful in 36 and failure in 16 patients. A significantly high failure rate of 80% was found when postero-medial release was done after 3 years of age as a sole procedure as compared to 25.5% only if age was less than 3 years (p< 0.05). The patient compliance to follow bracing protocol showed significantly high failure rate of 52.4% in non-compliant patients versus 16.1% in compliant patients (p< 0.05). A significantly high failure rate was also seen when bracing was not continued beyond 3 years after surgery (p< 0.05). Neurological clubfoot had a significantly high failure rate (80%) compared to idiopathic clubfoot (25.5%) (p< 0.05). A significantly high failure rate was also noted when infection and skin necrosis lead to skin grafting or flap coverage as compared to those healed with dressings alone (p< 0.05). Conclusion : Postero-medial release achieves best results in patients of less than 3 years of age and patients with compliance for bracing for at least up to 3-4 years following surgery and idiopathic clubfoot. Infection in clubfoot does not increase the failure rate unless it is severe enough to require plastic coverage. Any deviations from the above significantly increase the chances of failure of the procedure and hence can be labeled as the causes of failures of postero-medial release.
The host-galaxy of the gamma-ray Narrow-line Seyfert 1 galaxy 1H~0323+342
J. León-Tavares,J. Kotilainen,V. Chavushyan,C. A?orve,I. Puerari,I. Cruz-González,V. Pati?o-álvarez,S. Antón,A. Carrami?ana,L. Carrasco,J. Guichard,K. Karhunen,A. Olguín-Iglesias,J. Sanghvi,J. R. Valdes
Physics , 2014, DOI: 10.1088/0004-637X/795/1/58
Abstract: We present optical and near infrared (NIR) imaging data of the radio-loud Narrow-line Seyfert 1 galaxy 1H 0323+342, which shows intense and variable gamma-ray activity discovered by the Fermi satellite with the Large Area Telescope. NIR and optical images are used to investigate the structural properties of the host galaxy of 1H 0323+342; this together with optical spectroscopy allowed us to examine its black hole mass. Based on the 2D multiwavelength surface brightness modeling, we find that, statistically, the best model fit is a combination of a nuclear component and a S\'ersic profile (n~2.8). However, the presence of a disc component (with a small bulge n~1.2) remains also a possibility and cannot be ruled out with the present data. Although at first glance a spiral-arm like structure is revealed in our images, a 2D Fourier analysis of the imagery suggests that such structure corresponds to an asymmetric ring, likely associated to a recent violent dynamical interaction. We discuss our results on the context of relativistic jets production and galaxy evolution.
Conjunctival transplantation for corneal surface reconstruction - case reports and review of literature
Sanghvi Alkesh,Basti Surendra
Indian Journal of Ophthalmology , 1996,
Abstract: Corneal persistent epithelial defects (PED) can occur due to various causes. In diffuse ocular surface disease, they often occur secondary to depletion of limbal stem cells. A number of complications occur secondary to PED and successful treatment usually requires conjunctival surgeries for corneal surface reconstruction. We report two cases of chemical injury successfully treated by two such procedures. This report highlights the encouraging results of limbal transplantation and reviews the literature in the management of PED with limbal stem cell loss.
Third ventricular dermoid: An unusual tumor at an unusual site
Iyer Veena,Sanghvi Darshana
Neurology India , 2008,
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