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Search Results: 1 - 10 of 225049 matches for " R. Babu "
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Study of the Oceanic Heat Budget Components over the Arabian Sea during the Formation and Evolution of Super Cyclone, Gonu  [PDF]
P. R. Jayakrishnan, C. A. Babu
Atmospheric and Climate Sciences (ACS) , 2013, DOI: 10.4236/acs.2013.33030
Abstract:

Oceans play a vital role in the global climate system. They absorb the incoming solar energy and redistribute the energy through horizontal and vertical transports. In this context it is important to investigate the variation of heat budget components during the formation of a low-pressure system. In 2007, the monsoon onset was on 28th May. A well-marked low-pressure area was formed in the eastern Arabian Sea after the onset and it further developed into a cyclone. We have analysed the heat budget components during different stages of the cyclone. The data used for the computation of heat budget components is Objectively Analyzed air-sea flux data obtained from WHOI (Woods Hole Oceanographic Institution) project. Its horizontal resolution is 1° × 1°. Over the low-pressure area, the latent heat flux was 180 Wm2. It increased to a maximum value of 210 Wm2 on 1st June 2007, on which the system was intensified into a cyclone (Gonu) with latent heat flux values ranging from 200 to 250 Wm2. It sharply decreased after the passage of cyclone. The high value of latent heat flux is attributed to the latent heat release due to the cyclone by the formation of clouds. Long wave radiation flux is decreased sharply from 100 Wm2 to 30 Wm2 when the low-pressure system intensified into a cyclone. The decrease in long wave radiation flux is due to the presence of clouds. Net heat flux also decreases sharply to 200 Wm2 on 1st June 2007. After the passage, the flux value increased to normal value (150 Wm2) within one day. A sharp increase in the sensible heat flux value (20 Wm2) is observed on 1st June 2007 and it decreased thereafter. Short wave radiation flux decreased from 300 Wm2 to 90 Wm2

Synthesis, Growth and Characterization of Organic Nonlinear Optical Single Crystals of 4-Bromo-4’-Methyl Benzylidene Aniline  [PDF]
L. Jothi, R. Ramesh Babu, K. Ramamurthi
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2014, DOI: 10.4236/jmmce.2014.24036
Abstract:

Organic nonlinear optical material of 4-bromo-4’-methyl benzylidene aniline (BMBA) was synthesized and single crystal of BMBA was grown by solvent evaporation method at room temperature using ethanol as solvent. The crystalline nature of the grown crystals was confirmed using powder X-ray diffraction studies. The crystals were also characterized by single crystal X-ray diffraction method and their lattice parameters were determined. Thermal properties of BMBA were evaluated with thermogravimetric, differential thermal and differential scanning calorimetric analyses. Fourier transform infrared and FT-Raman spectral studies were carried out on the BMBA material to confirm the synthesized compound. 1H and 13C-nuclear magnetic resonance spectral studies were recorded to elucidate the structure of the grown crystals. Fluorescence spectrum recorded shows a peak at 485 nm. UV-Vis-NIR spectral analysis shows transmittance of ~92% in the visible region. The mechanical stability was analyzed by Vickers microhardness tester and the work hardening coefficient of the grown crystal was calculated. Second harmonic generation efficiency of the grown crystal measured by Kurtz powder technique is ~1.8 times that of potassium dihydrogen orthophosphate.

Assessment of Convective Activity Using Stability Indices as Inferred from Radiosonde and MODIS Data  [PDF]
P. R. Jayakrishnan, C. A. Babu
Atmospheric and Climate Sciences (ACS) , 2014, DOI: 10.4236/acs.2014.41014
Abstract:

The combined use of both radiosonde data and three-dimensional satellite derived data over ocean and land is useful for a better understanding of atmospheric thermodynamics. Here, an attempt is made to study the thermodynamic structure of convective atmosphere during pre-monsoon season over southwest peninsular India utilizing satellite derived data and radiosonde data. The stability indices were computed for the selected stations over southwest peninsular India viz: Thiruvananthapuram and Cochin, using the radiosonde data for five premonsoon seasons. The stability indices studied for the region are Showalter Index (SI), K Index (KI), Lifted Index (LI), Total Totals Index (TTI), Humidity Index (HI), Deep Convective Index (DCI) and thermodynamic parameters such as Convective Available Potential Energy (CAPE) and Convective Inhibition Energy (CINE). The traditional Showalter Index has been modified to incorporate the thermodynamics over tropical region. MODIS data over South Peninsular India are also used for the study. When there is a convective system over south peninsular India, the value of LI over the region is less than ?4. On the other hand, the region where LI is more than 2 is comparatively stable without any convection. Similarly, when KI values are in the range 35 to 40, there is a possibility for convection. The threshold value for TTI is found to be between 50 and 55. Further, we found that prior to convection, dry bulb temperature at 1000, 850, 700 and 500 hPa is minimum and the dew point temperature is a maximum, which leads to increase in relative humidity. The total column water vapor is maximum in the convective region and minimum in the stable region. The threshold values for the different stability indices are found to agree with that reported in literature.

Recovery of Ilmenite and Other Heavy Minerals from Teri Sands (Red Sands) of Tamil Nadu, India  [PDF]
N. Babu, N. Vasumathi, R. Bhima Rao
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2009, DOI: 10.4236/jmmce.2009.82013
Abstract: The red sand which is known as Teri sand in Tamil Nadu consists of 5.5% Total Heavy Minerals (THM) out of which 3.7% is ilmenite. The other minerals, zircon, sillimanite and garnet are in the order of abundance identified. On processing this feed to recover ilmenite by using spirals followed by dry high intensity magnetic separator and high tension separator, the ilmenite concentrate obtained contains 99.1% ilmenite with 3.5% yield and 94% recovery. The other heavy minerals, including zircon (53.3%) and sillimanite (31.7%), could be further processed for recovery of individual mineral of zircon and sillimanite by judicious combination of gravity and flotation processes.
The Paradoxical Effect of Paraquat on Leucyl-tRNA Levels in E. coli Provides New Insights for Amino Acid Therapy in Humans  [PDF]
Babu V. Bassa, Olen R. Brown
CellBio (CellBio) , 2018, DOI: 10.4236/cellbio.2018.74005
Abstract: Dihydroxyacid dehydratase (DHAD), the rate-limiting enzyme in the synthesis of branched-chain (BCA) amino acids in bacteria and plants, is sensitive to oxyradical toxicity. Oxidant stress reversibly inactivates DHAD and causes starvation for BCA and reversible cessation of growth in Escherichia coli [1][2]. To better understand the underlying toxicity mechanisms, we have determined the cellular concentrations of charged-tRNAs for BCA, in E. coli treated with the redox-active chemical, paraquat. Contrary to expectation, in the paraquat-treated cells, the concentration of only charged leucyl-tRNA decreased dramatically; whereas, the concentrations of the other BCAs (valine and isoleucine) increased. This paradoxical result, the “paraquat effect” can be best explained if leucine is the most abundant amino acid in the E. coli proteins and therefore the rate-limiting building block in their synthesis. Based on this assumption, we investigated the concentration of free amino acids in E. coli and their relative abundances in E. coli proteins. Protein amino acid frequencies were determined by analyzing one-hundred gene bank protein sequences with software developed as described in Methods. Leucine is the most abundant amino acid in the E. coli proteins (10%) and consequently, the cellular free leucine concentration is smaller and the native charged-leucyl-tRNA levels are much higher than those of valine and isoleucine. This has relevance to humans because: leucine-deprivation was shown to be beneficial in tumor suppression [3], and leucine-supplementation was beneficial in the recovery from exercise-induced muscle loss [4][5], and leucine also occurs at a higher frequency in almost all human proteins. In three human protein categories, we examined it ranged from 9% to 17%. This predominance of leucine in proteins would make cells vulnerable to impairment of the leucine pools and could explain our results in E. coli and some of the biological effects of free leucine in humans.
Effect of Tsunami in the Ilmenite Population: An Examination through X-Ray Diffraction, Scanning Electron Microscopy and Inductively Coupled Plasma Atomic Emission  [PDF]
Babu Nallusamy, Sinirani Babu, M. Sundararajan, P. Seralathan, R. Bhima Rao, P.N. Mohan Das
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2010, DOI: 10.4236/jmmce.2010.911073
Abstract: Kerala state in the SW part of Indian subcontinent hosts one of the best beach placer deposits in the world. The near shore deposit is ~140Mt and is very rich in heavy minerals, often up to 70%, and ilmenite forms its chief constituent. The seasonal enrichment of this deposit takes place through monsoonal activity and the recent tsunami (24 December 2004) had significantly contributed its share. Mineralogical and chemical variation of the surface (pre- and posttsunamigenic) as well as subsurface ilmenites (4-5m depth) of this deposit has been investigated. SEM examination on ilmenites of pre-tsunamigenic period conveys that the micromorphology represents mostly of mechanical activities rather than chemical and solution activities. Both post-tsunamigenic and subsurface ilmenites were influenced dominantly by solution and chemical alteration. The pre-tsunamigenic (surficial) ilmenite grains consist only of rutile as an altered product with a small FeO – Fe2O3 ratio. However, the presence of considerable altered products such as rutile and pseudorutile in the post-tsunamigenic and subsurface ilmenite indicates that the ilmenite alteration is in an advanced state. Regarding trace element composition, it was found that Al, Mg, Na, Ca, Cd, Co, K, Sr and Pb have higher contents in both core and post-tsunamigenic ilmenite than the pre-tsunamigenic ilmenite. These elements play an important role in understanding the behavior of the minerals during beneficiation and further processing. The relative lesser content of such elements in the onshore pre-tsunamigenic ilmenite grains reveals that the chemical leaching has not been active compared to the ilmenite concentrates from the shallow sea that have been brought by the tsunami and also to that have been deposited earlier and now seen underneath up to a depth of ~5m.
Rindopepimut: an evidence-based review of its therapeutic potential in the treatment of EGFRvIII-positive glioblastoma
Babu R, Adamson DC
Core Evidence , 2012, DOI: http://dx.doi.org/10.2147/CE.S29001
Abstract: dopepimut: an evidence-based review of its therapeutic potential in the treatment of EGFRvIII-positive glioblastoma Review (1317) Total Article Views Authors: Babu R, Adamson DC Published Date September 2012 Volume 2012:7 Pages 93 - 103 DOI: http://dx.doi.org/10.2147/CE.S29001 Received: 15 June 2012 Accepted: 12 July 2012 Published: 14 September 2012 Ranjith Babu, D Cory Adamson Division of Neurosurgery, Department of Surgery, Duke University Medical Center, Durham, NC, USA Abstract: Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults and is universally fatal. Despite surgical resection, radiotherapy, and systemic chemotherapy, the median overall survival is less than 15 months. As current therapies are not tumor-specific, treatment commonly results in toxicity. The epidermal growth factor receptor variant III (EGFRvIII) is a naturally occurring mutant of EGFR and is expressed on approximately 20% to 30% of GBMs. As it is not expressed on normal cells, it is an ideal therapeutic target. Rindopepimut is a peptide vaccine which elicits EGFRvIII-specific humoral and cellular immune responses. Phase I and II clinical trials have demonstrated significantly higher progression-free and overall survival times in vaccinated patients with EGFRvIII-expressing GBM tumors. Side effects are minimal and mainly consist of hypersensitivity reactions. Due to the efficacy and safety of rindopepimut, it is a promising therapy for patients with GBM. Currently, rindopepimut is undergoing clinical testing in an international Phase III trial for newly diagnosed GBM and a Phase II trial for relapsed GBM.
Generalization of fixed point theorems relating to the diameter of orbits by using a control function
G. V. R. Babu
Tamkang Journal of Mathematics , 2004, DOI: 10.5556/j.tkjm.35.2004.159-168
Abstract: The main purpose of this paper is to obtain fixed points for a selfmap $T$ of a metric space which is $T$-orbitally complete under a more general contraction type condition by using a certain continuous control function. Further generalization relating to the diameter of orbits is given.
Common Fixed Point Theorems of Generalized Contraction / Zamfirescu Pair of maps in Cone metric spaces
G. V. R. BABU
Albanian Journal of Mathematics , 2010,
Abstract: We prove the existence of common xed points of a generalizedcontraction / Zamrescu pair of maps in a complete cone metric space. Ourresults generalize the results of Huang anf Zhang [L-G. Huang, X. Zhang:Cone metric spaces and xed point theorems of contractive mappings, J. Math.Anal. Appl. 332 (2007) 1468{1476] and extend the results of Rezapour andHamlbarani [Sh. Rezapour, R. Hamlbarani: Some notes on the paper Conemetric spaces and xed point theorems of contractive mappings", J. Math.Anal. Appl. 345 (2008) 719{724].
Effect of Probiotics on the Hatchery Seed Production of Black Tiger Shrimp, Penaeus monodon (Fabricius)
P. Soundarapandian,R. Babu
International Journal of Animal and Veterinary Advances , 2010,
Abstract: In recent years, the diseases of shrimps hindered the development of shrimp culture. Hence, the use of probiotic bacteria in aquaculture has tremendous scope and the study of the application of probiotics in aquaculture has a glorious future. In the present study, the probiotics was applied (experimental) for the larval rearing of P. monodon which is compared with control tanks (without probiotics). The temperature and alkalinity of both control and experimental tanks were more of less same. The pH of the control tank w as 8.4 and the experimental tank was 8.2.The dissolved oxygen was higher in experimental tank (6.12ml/litre) and lower in control tanks (5.75ml/litre). Likewise, the ammonia was higher in control tanks (0.19 mg/litre) rather than experimental tanks (0.15mg/litre). The survival rate of different larval stages (nauplii, zoea and mysis) were maximum in the present study than that of control tanks. The final survival rate of the post larvae from the control and experimental tank was 70 and 30% respectively. The average length of all post larvae was maximum when reared in experimental tank than control tanks. The general conclusion obtained from the present study is that the probiotics plays a vital role in maintaining water quality parameters throughout the larval cycle. It is clear from the microbial load data that vibrio sp. is dominant in the control tanks than in experimental tanks.
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