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Search Results: 1 - 10 of 223873 matches for " R Vijayalakshmy "
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Role of Duration of Diabetes in the Development of Nephropathy in Type 2 Diabetic Patients
Jiji Inassi,R Vijayalakshmy
National Journal of Medical Research , 2013,
Abstract: Introduction: Diabetes has now become the most common single cause of end stage renal disease and about 40% of diabetic patients develop nephropathy. The present study was conducted to find out the relation between duration of diabetes & development of renal disease. Methodology: The study was conducted in 120 patients with Type 2 diabetes. Three groups were selected with 40 patients in each group with diabetes of <5year duration, 5-10year duration and >10year duration. 40 normal healthy adults were included in the control group. Parameters like BP, blood urea, serum creatinine, urine microprotein were compared with controls. Results: As duration increases, there is impairment of renal function as evidenced by increase in blood urea, serum creatinine & microproteinuria. Statistically significant increase in BP was also observed with increase in duration. Both metabolic & hemodynamic factors play a decisive role in the development of nephropathy. AGEs, PDGF, TGFβ, VEGF, and Angiotensin II etc. stimulate growth & fibrotic factors leading to renal damage. Conclusion: Screening for microalbuminuria will allow early identification of patients with nephropathy. It has been shown that meticulous glycemic & bloodpressure control can slow the progression of diabetic nephropathy. Developing countries like India with its large burden of diabetes should evolve strategies for prevention of its secondary complications. [Natl J of Med Res 2013; 3(1.000): 5-8]
Trichoadenoma of Nikolowski
Pavithran K,Vijayalakshmy A
Indian Journal of Dermatology , 1996,
Abstract: ABSTRACT: A case of trichoadenoma developing on the shaft of penis is reported in a young male. Histology revealed numerous horn cysts, each surrounded by eosinophilic cells. Its differentiating features from trichoepithelioma, histopathologically, are described.
Primary neuroendocrine carcinoma (Merkel′s cell carcinoma) of the vulva mimicking as a Bartholin′s gland abscess
Pawar Rajeshwari,Vijayalakshmy Attuveppil,Khan Sultana,Ramadhan al Lawati Fatma
Annals of Saudi Medicine , 2005,
Power Aware Routing Protocol (PARP) for Wireless Sensor Networks  [PDF]
R. Prema, R. Rangarajan
Wireless Sensor Network (WSN) , 2012, DOI: 10.4236/wsn.2012.45019
Abstract: Several wireless sensor network applications ought to decide the intrinsic variance between energy efficient communication and the requirement to attain preferred quality of service (QoS) such as packet delivery ratio, delay and to reduce the power consumption of wireless sensor nodes. In order to address this challenge, we propose the Power Aware Routing Protocol (PARP), which attains application-specified communication delays at low energy cost by dynamically adapting transmission power and routing decisions. Extensive simulation results prove that the proposed PARP attains better QoS and reduced power consumption.
An Innovative Low Cost EM Pollution Measurement System  [PDF]
R. Sittalatchoumy, R. Seetharaman
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.78176
Abstract: Mobile phones and other electronic devices are emitting radiations that will provide harmful effects to the human health. In order to measure the radiation, an innovative low cost measurement system is proposed in this paper. The ideology is to simplify the circuit’s value by converting a voltage detecting circuit to a field detecting circuit by finding an optimum resistance on trial and error basis. The requirement for a trial and error technique is to not allow too high or too low resistance which can be either short or open, resulting provides more damage to the circuit.
Ant Lion Optimization Approach for Load Frequency Control of Multi-Area Interconnected Power Systems  [PDF]
R. Satheeshkumar, R. Shivakumar
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.79206
Abstract: This work proposes a novel nature-inspired algorithm called Ant Lion Optimizer (ALO). The ALO algorithm mimics the search mechanism of antlions in nature. A time domain based objective function is established to tune the parameters of the PI controller based LFC, which is solved by the proposed ALO algorithm to reach the most convenient solutions. A three-area interconnected power system is investigated as a test system under various loading conditions to confirm the effectiveness of the suggested algorithm. Simulation results are given to show the enhanced performance of the developed ALO algorithm based controllers in comparison with Genetic Algorithm (GA), Particle Swarm Optimization (PSO), Bat Algorithm (BAT) and conventional PI controller. These results represent that the proposed BAT algorithm tuned PI controller offers better performance over other soft computing algorithms in conditions of settling times and several performance indices.
Obtaining Optimal Solution by Using Very Good Non-Basic Feasible Solution of the Transportation and Linear Programming Problem  [PDF]
R. R. K. Sharma
American Journal of Operations Research (AJOR) , 2017, DOI: 10.4236/ajor.2017.75021
Abstract: For the transportation problem, Sharma and Sharma [1] have given a very computationally efficient heuristic (runs in O(c*n2) time) to give very good dual solution to transportation problem. Sharma and Prasad [2] have given an efficient heuristic (complexity O(n3) procedure to give a very good primal solution (that is generally non-basic feasible solution) to transportation problem by using the very good dual solution given by Sharma and Sharma [2]. In this paper we use the solution given by Sharma and Prasad [2] to get a very good Basic Feasible Solution to transportation problem, so that network simplex (worst case complexity (O(n3*(log(n))) can be used to reach the optimal solution to transportation problem. In the second part of this paper, we give a simple heuristic procedure to get a very good BFS to linear programming problem from the solution given by Karmarkar [3] (that generally produces a very good non-basic feasible solution in polynomial time (O(n5.5)). We give a procedure to obtain a good BFS for LP by starting from the solution given by Karmarkar [3]. We note that this procedure (given here) is significantly different from the procedure given in [4].
Power Analysis of Sensor Node Using Simulation Tool  [PDF]
R. Sittalatchoumy, R. Kanthavel, R. Seetharaman
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.713348
Abstract: Power consumption of sensor node is analyzed in this paper. In order to analyze the energy consumption, the node model is simulated using Proteus Software tool. The proposed sensor nodes power characteristics are measured by using different combinations of microprocessors and sensors. Using this, the energy consumption of the node is calculated. This is a cost-effective method and provides appropriate power model for specific applications.
Studies on Dissolution Behaviour of Nanoparticulate Curcumin Formulation  [PDF]
R. Ravichandran
Advances in Nanoparticles (ANP) , 2013, DOI: 10.4236/anp.2013.21010

Curcumin is the main biologically active phytochemical compound of turmeric that has been widely used by ancient cultures throughout Asia. However the dissolution rate limited absorption and pre-absorption degradation limits its use as a potential therapeutic. In this study an attempt has been made to overcome the above limitations by curcumin delivery through nanotechnology. Nanocurcumin solid dosage formulations were prepared and studied for its dissolution behaviour. Considerable improvement in the dissolution behavior was observed in the drug nanocrystal-loaded solid dosage forms. This is expected to enhance the bioavailability of poorly soluble medicinal herbs such as turmeric in the body.

Pharmacokinetic Study of Nanoparticulate Curcumin: Oral Formulation for Enhanced Bioavailability  [PDF]
R. Ravichandran
Journal of Biomaterials and Nanobiotechnology (JBNB) , 2013, DOI: 10.4236/jbnb.2013.43037

Curcumin, a bioactive component of turmeric, which is a commonly used spice and nutritional supplement, is isolated from the rhizomes of Curcuma longa Linn. (Zingiberaceae). In recent years, the potential pharmacological actions of Curcumin in inflammatory disorders, cardiovascular disease, cancer, Alzheimer’s disease and neurological disorders have been shown. However, the clinical application of Curcumin is severely limited by its main drawbacks such as instability, low solubility, poor bioavailability and rapid metabolism. Multifarious nanotechnology-based drug delivery systems for Curcumin including liposomes, polymeric nanoparticles, solid lipid nanoparticles, micelles, nanogels, nanoemulsions, complexes and dendrimer/dimer, have been attempted to enhance the oral bioavailability, biological activity or tissue-targeting ability of Curcumin. We attempted the nanosuspensions based delivery of curcumin. Nanonisation renders curcumin completely dispersible in aqueous media. To enhance the curcumin absorption by oral administration, nanoparticulate solid oral formulation of curcumin was prepared by us and the resulting capsule was then examined for its efficiency on bioavailability in Male Wistar rats at a dose of 100 mg curcumin/kg body weight and the pharmacokinetic parameters were compared to those of normal curcumin powder and a commercial curcumin capsule CUR-500. The bio-distribution of curcumin in organs of rat was also studied. Nanoparticulation significantly raised the curcumin concentration in selective organs in the body. The results obtained provide promising results for nanoparticulate Curcumin to improve its biological activities. Enhanced bioavailability of curcumin in the form of nanoparticle is likely to bring this promising natural product to the forefront of therapeutic agents for treatment of human disease. The available information also strongly suggests that nano-formulation of ingredients such as curcumin may be used as a novel nutrient delivery system too.

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