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Search Results: 1 - 10 of 58820 matches for " Qiaohui Yang "
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DNA methylation of the Monoamine Oxidases A and B genes in postmortem brains of subjects with schizophrenia  [PDF]
Qiaohui Yang, Keiko Ikemoto, Satoshi Nishino, Junko Yamaki, Yasuto Kunii, Akira Wada, Yoshimi Homma, Shin-Ichi Niwa
Open Journal of Psychiatry (OJPsych) , 2012, DOI: 10.4236/ojpsych.2012.224053
Abstract: Aims: We focused on DNA methylation of the promoter regions of the Monoamine Oxidase (MAO) A and B genes from postmortem brains of subjects with schizophrenia. Methods: We determined levels of DNA methylation using genomic DNA samples purified from four brain areas: prefrontal cortex (PFC), hippocampus, occipital cortex and nucleus accumbens (NAc), by a bisulfite sequencing method from seven normal subjects and six subjects with schizophrenia. Results: Although very few methylated CpGs of the MAOA and MAOB genes were detected in male samples, various DNA methylation patterns were present in female samples, and some differences were found in such patterns between normal subjects and subjects with schizophrenia. In the PFC, the average level of methylation of both genes was significantly higher in subjects with schizophrenia than in normal subjects. The content of highly methylated alleles of the MAOA gene in the NAc was significantly associated with schizophrenia, with similar results obtained for the MAOB gene in both the NAc and PFC. Some CpG sites showed higher levels of methylation in schizophrenia than in normal subjects. Conclusions: Levels of methylation were quite high in NAc and PFC in female subjects with schizophrenia compared with those in female normal subjects.
Frequency of TLR 2, 4, and 9 Gene Polymorphisms in Chinese Population and Their Susceptibility to Type 2 Diabetes and Coronary Artery Disease
Fengjing Liu,Weixin Lu,Qiaohui Qian,Weigang Qi,Jifan Hu,Bo Feng
Journal of Biomedicine and Biotechnology , 2012, DOI: 10.1155/2012/373945
Abstract: Toll-like receptors (TLRs) are pivotal components of the innate immune response. Activation of the innate immune system and subsequent chronic low-grade inflammation are thought to be involved in the pathogenesis of atherosclerosis and type 2 diabetes. In the study, we genotyped TLRs gene polymorphisms, including TLR2 Arg677Trp and Arg753Gln, TLR4 Asp299Gly and Thr399Ile, TLR9-1486T/C and -1237T/C. The frequencies of TT, TC and CC genotype of TLR9-1486T/C mutation were 39.6%, 45.8% and 14.6%, respectively; the frequencies of T allele and C allele were 62.5% and 37.5%. However, neither of these parameters was statistically significant among study groups. In addition, we were surprised to find that the commonly reported TLR SNPs in the Western countries, like TLR2 Arg677Trp or Arg753Gln, TLR4 Asp299Gly or Thr399Ile and TLR9-1237T/C, were not polymorphic at all in all study subjects. In conclusion, our data suggests that TLR2 Arg677Trp or Arg753Gln, TLR4 Asp299Gly or Thr399Ile and TLR9-1237T/C polymorphisms have low frequency and TLR9-1486T/C polymorphism may not be a suitable marker in predicting the susceptibility to type 2 diabetes or coronary artery disease in the Chinese Han population.
Fundamental Research on the Administrative Discretion Standard  [PDF]
Yang Yang
Beijing Law Review (BLR) , 2012, DOI: 10.4236/blr.2012.33017
Abstract: This paper describes a system for the analysis of the administrative discretion standard. Now, it is a new phenomenon in the practice of administrative law enforcement. We shall first briefly introduce fuzzy sets and related concepts of the administrative discretion standard, and then, we try to introduce the intrinsic value of its legitimacy. At the same time, the research standard of interpretation, procedure and “requirements-effect” are discussed based on the analysis through its content. From the above discussion, the conclusion can be reached that it is the power’s structure to deal with individuals and societies on the micro side.
Study of Improving the Management System of Temporary Resident Population  [PDF]
Yang Yang
Current Urban Studies (CUS) , 2013, DOI: 10.4236/cus.2013.14019
Abstract: Due to the function for management is abnormally amplified, its service’s function is not well reflected when it is carried out for the Management System for Temporary Resident Population. So it will face enormous pressure and there are many problems for the management system for the temporary residential permit and it need to further be strict and improved. Our government should change from the prevention and control management for the past into the service management which emphasizes on both management and service according to the concept of people-oriented on the basis of retaining and improving the tem-porary residence registration in current. Firstly, they should further intensify the reform of the household registration system to introduce the concept of citizen treatment and continue to reinforce the value of temporary residential permits. Secondly, the departments will perform their functions and adhere to com-prehensively management. Thirdly, they should establish the population management information net-work to share the resources.
Procedure Standard and Administrative Investigation
—Realization of the Self-Discipline Principle
 [PDF]

Yang Yang
Open Journal of Political Science (OJPS) , 2013, DOI: 10.4236/ojps.2013.34016
Abstract:

How to effectively protect the interests and rights of individuals and how to even realize a higher-level goal, individual justice and creative property are disturbing problems in administrative investigation. However, the complexity of the problem is increased because it includes arbitrary investigation and compulsory investigation. The specialness of the problem can be discovered through the clarity of administrative investigations on the attribution of concrete administrative acts. There is another effective method, namely the procedure standard reflecting the self-discipline principle except the mainstream method of right-control (i.e. judicial review). It is a combination of self-discipline with right-control, and may be one of the methods keeping pace with judicial review to realize the above-mentioned goal.

Analysis of Solution to Environmental Law Education for College Students  [PDF]
Yang Yang
Beijing Law Review (BLR) , 2013, DOI: 10.4236/blr.2013.43013
Abstract:

The environmental crisis is one of three major crises to human’s development. But there are a series of issues in present for environmental law education of college students, such as this course, which are low offered and lack of sustainability, colleges and universities do not pay enough attention to it. They are weak in the relevant basic theory and they are lack of vocational training and so on. In order to solve the above problems, we can try to do the “two combinations”. The first is the combination vocational training and basic knowledge and the second is combining vocational training in the classroom with outside of the classroom in environmental law.

Study of the Development of Youth Culture under the Background of Advanced Culture  [PDF]
Yang Yang
Sociology Mind (SM) , 2014, DOI: 10.4236/sm.2014.41008
Abstract:

It refers to the sum total of value system, behavioral norms and social relationships accepted by young generations for youth culture which has the characteristic of hierarchy, variability and rebellion. It has also had positive and negative functions. It is the mutual influence and mutual promoting relationship between the youth culture and advanced culture. Comrade Hu Jintao puts forward three wishes to the majority of young people, but also gives the youth culture three new elements, which are diligent in learning, good at creating and making contribution. In the new period, the youth culture will further be boosted when we are developing advanced culture.

Study of the Role of NGO in Strengthening the Food Safety and Construction of the Relevant Law  [PDF]
Yang Yang
Open Journal of Political Science (OJPS) , 2014, DOI: 10.4236/ojps.2014.43015
Abstract:
Food safety, which is a key part of livelihood projects, is not only closely related to the thousands of households table, but enormously affecting the whole country. The government departments as the manager of the public interests have been committed to strengthen the construction of food safety, but its results are always unremarkable. In order to prevent “the government failure” in the process of food supervision, the food NGO is now entering the people’s view. It has a comparative advantage in specialization, independence and efficiency, however, as an emerging force, it is also plagued by problems such as small number, weak power, lack of necessary support in law and so on. Therefore, the food NGO might be worth a great deal; it is essential for the system construction especially the construction of relevant Law apart from continuous development and ceaseless accumulation.
Study of the Standard Insurance Provisions’ Interpretation  [PDF]
Yang Yang
Open Journal of Social Sciences (JSS) , 2014, DOI: 10.4236/jss.2014.24021
Abstract: The new insurance law has been implemented for a long time, but it is still disputed frequently for the application of standard insurance clause. We can see this from many cases, e.g. the Sued People’s Insurance Company of China LLC, Jinyun Branch office Insurance contract Dispute Case by Li Shangzhi. This paper is trying to take the standard insurance clause as the beginning point to briefly analyze the reason for the terms’ understanding differences and to study their unfavorable interpretation principle through comparing the provisions’ samples in the old and new insurance law, which can be looked forward to providing some ideas for their corresponding practice.
Studying of e-Government Affairs—The Foothold for the Popular Cultural Service in New Rural Area  [PDF]
Yang Yang
Open Journal of Social Sciences (JSS) , 2014, DOI: 10.4236/jss.2014.211015
Abstract: There are flaws in the field of the popular cultural service such as its methods, means and measures, but the e-government Affairs has opened up the new direction to investigate this field. As there are problems of hardware, effect, management to the e-government affairs as the standing factor for popular cultural service, it needs the follow-up of the personnel, the way of management and the scientific assessment method. There is no doubt that the formation of new fashion in new rural area depends on the service standard of popular culture. It is the first step to advance the standard of e-government affairs under the circumstances that the popular culture are improved.
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