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Search Results: 1 - 10 of 54348 matches for " Qiang Wu "
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The w-index: A significant improvement of the h-index
Qiang Wu
Physics , 2008, DOI: 10.1002/asi.21276
Abstract: I propose a new measure, the w-index, as a particularly simple and useful way to assess the integrated impact of a researcher's work, especially his or her excellent papers. The w-index can be defined as follows: If w of a researcher's papers have at least 10w citations each and the other papers have fewer than 10(w+1) citations, his/her w-index is w. It is a significant improvement of the h-index.
Research on Blind Source Separation for Machine Vibrations  [PDF]
Weiguo HUANG, Shuyou WU, Fangrang KONG, Qiang WU
Wireless Sensor Network (WSN) , 2009, DOI: 10.4236/wsn.2009.15054
Abstract: Blind source separation is a signal processing method based on independent component analysis, its aim is to separate the source signals from a set of observations (output of sensors) by assuming the source signals independently. This paper reviews the general concept of BSS firstly; especially the theory for convolutive mixtures, the model of convolutive mixture and two deconvolution structures, then adopts a BSS algorithm for convolutive mixtures based on residual cross-talking error threshold control criteria, the simulation testing points out good performance for simulated mixtures.
Impact of Bursty Human Activity Patterns on the Popularity of Online Content
Qiang Yan,Lianren Wu
Discrete Dynamics in Nature and Society , 2012, DOI: 10.1155/2012/872908
Abstract: The dynamics of online content popularity has attracted more and more researches in recent years. In this paper, we provide a quantitative, temporal analysis about the dynamics of online content popularity in a massive system: Sina Microblog. We use time-stamped data to investigate the impact of bursty human comment patterns on the popularity of online microblog news. Statistical results indicate that the number of news and comments exhibits an exponential growth. The strength of forwarding and comment is characterized by bursts, displaying fat-tailed distribution. In order to characterize the dynamics of popularity, we explore the distribution of the time interval Δ between consecutive comment bursts and find that it also follows a power-law. Bursty patterns of human comment are responsible for the power-law decay of popularity. These results are well supported by both the theoretical analysis and empirical data.
Cloning and Comparative Analyses of the Zebrafish Ugt Repertoire Reveal Its Evolutionary Diversity
Haiyan Huang,Qiang Wu
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0009144
Abstract: UDP-glucuronosyltransferases (Ugts) are a supergene family of phase II drug-metabolizing enzymes that catalyze the conjugation of numerous hydrophobic small molecules with the UDP-glucuronic acid, converting them into hydrophilic molecules. Here, we report the identification and cloning of the complete zebrafish Ugt gene repertoire. We found that the zebrafish genome contains 45 Ugt genes that can be divided into three families: Ugt1, Ugt2, and Ugt5. Both Ugt1 and Ugt2 have two unlinked clusters: a and b. The Ugt1a, Ugt1b, Ugt2a, and Ugt2b clusters each contain variable and constant regions, similar to that of the protocadherin (Pcdh), immunoglobulin (Ig), and T-cell receptor (Tcr) clusters. Cloning the full-length coding sequences confirmed that each of the variable exons is separately spliced to the set of constant exons within each zebrafish Ugt cluster. Comparative analyses showed that both a and b clusters of the zebrafish Ugt1 and Ugt2 genes have orthologs in other teleosts, suggesting that they may be resulted from the “fish-specific” whole-genome duplication event. The Ugt5 genes are a novel family of Ugt genes that exist in teleosts and amphibians. Their entire open reading frames are encoded by single large exons. The zebrafish Ugt1, Ugt2, and Ugt5 genes can generate additional transcript diversity through alternative splicing. Based on phylogenetic analyses, we propose that the ancestral tetrapod and teleost Ugt1 clusters contained multiple Ugt1 paralogs. After speciation, these ancestral Ugt1 clusters underwent lineage-specific gene loss and duplication. The ancestral vertebrate Ugt2 cluster also underwent lineage-specific duplication. The intronless Ugt5 open reading frames may be derived from retrotransposition followed by gene duplication. They have been expanded dramatically in teleosts and have become the most abundant Ugt family in these lineages. These findings have interesting implications regarding the molecular evolution of genes with diversified variable exons in vertebrates.
Adaptive evolution of multiple-variable exons and structural diversity of drug-metabolizing enzymes
Can Li, Qiang Wu
BMC Evolutionary Biology , 2007, DOI: 10.1186/1471-2148-7-69
Abstract: We found that there are species-specific variable-exon duplications and mutations in the vertebrate Ugt1, Gcnt2, and Ugt2a clusters and that their variable and constant genomic organizations are conserved and vertebrate-specific. In addition, analyzing the complete repertoires of closely-related Ugt2 clusters in humans, mice, and rats revealed extensive lineage-specific duplications. In contrast to the Pcdh gene clusters, gene conversion does not play a predominant role in the evolution of the vertebrate Ugt1, Gcnt2 and Ugt2 gene clusters. Thus, their tremendous diversity is achieved through "birth-and-death" evolution. Comparative analyses and homologous modeling demonstrated that vertebrate UGT proteins have similar three-dimensional structures each with N-terminal and C-terminal Rossmann-fold domains binding acceptor and donor substrates, respectively. Molecular docking experiments identified key residues in donor and acceptor recognition and provided insight into the catalytic mechanism of UGT glucuronidation, suggesting the human UGT1A1 residue histidine 39 (H39) as a general base and the residue aspartic acid 151 (D151) as an important electron-transfer helper. In addition, we identified four hypervariable regions in the N-terminal Rossmann domain that form an acceptor-binding pocket. Finally, analyzing patterns of nonsynonymous and synonymous nucleotide substitutions identified codon sites that are subject to positive Darwinian selection at the molecular level. These diversified residues likely play an important role in recognition of myriad xenobiotics and endobiotics.Our results suggest that enormous diversity of vertebrate multiple variable first exons is achieved through birth-and-death evolution and that adaptive evolution of specific codon sites enhances vertebrate UGT diversity for defense against environmental agents. Our results also have interesting implications regarding the staggering molecular diversity required for chemical detoxification and dr
Application of mechanochemical synthesis of advanced materials
Hao Wu,Qiang Li
Journal of Advanced Ceramics , 2012, DOI: 10.1007/s40145-012-0012-2
Abstract: An overview is given of recent development of mechanochemical processes for the preparation of advanced ceramics. Some fundamental mechanical effects are firstly compared and discussed. Several important application fields are listed as follow, stemming from oxide materials, non-oxide materials, and composite materials to nano-structured materials.
Reform and Development of Educational Administration System in China
Qiang Li,Zhongyuan Wu
International Education Studies , 2008, DOI: 10.5539/ies.v1n3p136
Abstract: The paper mainly introduces the development of the educational administration agency in China, including the evolution of the educational administration agency, the Course of instituting legal system of education in China, the missions of the now Minister of Education, questions emerged in the development of the educational administration system, and measures taken to reform the educational administration system. By the description of the development of the educational administration system from Oct. 1949 to 1998, the questions of the educational administration system are pointed out and measures taken to resolve those questions are brought forward, as follow: to reconstruct the educational administration functions, to provide the opportunity for the citizens to participate in educational management, and to improve the legal system for education needs to strengthen the supervision and evaluation of education.
Research on Chengdu Vegetables Marketing Based on STP Model
Qiang Liu,Xiumin Wu
Asian Social Science , 2013, DOI: 10.5539/ass.v9n4p221
Abstract: In this paper, we take the consumers in Chengdu vegetables market as samples, in the form of questionnaires and interviews, to study the consumer motivations and psychology, and make market segmentation of consumers. Results show that the consumers in Chengdu vegetables market can be divided into four types: the safety-pursuing type, the convenient and economical type, the family healthy type, and the fashionable type, among which the safety-pursuing type is the largest. Finally, authors put forward some suggestions for Chengdu vegetables market based on current conditions.
Auditory Sparse Representation for Robust Speaker Recognition Based on Tensor Structure
Wu Qiang,Zhang Liqing
EURASIP Journal on Audio, Speech, and Music Processing , 2008,
Abstract: This paper investigates the problem of speaker recognition in noisy conditions. A new approach called nonnegative tensor principal component analysis (NTPCA) with sparse constraint is proposed for speech feature extraction. We encode speech as a general higher-order tensor in order to extract discriminative features in spectrotemporal domain. Firstly, speech signals are represented by cochlear feature based on frequency selectivity characteristics at basilar membrane and inner hair cells; then, low-dimension sparse features are extracted by NTPCA for robust speaker modeling. The useful information of each subspace in the higher-order tensor can be preserved. Alternating projection algorithm is used to obtain a stable solution. Experimental results demonstrate that our method can increase the recognition accuracy specifically in noisy environments.
Auditory Sparse Representation for Robust Speaker Recognition Based on Tensor Structure
Qiang Wu,Liqing Zhang
EURASIP Journal on Audio, Speech, and Music Processing , 2008, DOI: 10.1155/2008/578612
Abstract: This paper investigates the problem of speaker recognition in noisy conditions. A new approach called nonnegative tensor principal component analysis (NTPCA) with sparse constraint is proposed for speech feature extraction. We encode speech as a general higher-order tensor in order to extract discriminative features in spectrotemporal domain. Firstly, speech signals are represented by cochlear feature based on frequency selectivity characteristics at basilar membrane and inner hair cells; then, low-dimension sparse features are extracted by NTPCA for robust speaker modeling. The useful information of each subspace in the higher-order tensor can be preserved. Alternating projection algorithm is used to obtain a stable solution. Experimental results demonstrate that our method can increase the recognition accuracy specifically in noisy environments.
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