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Search Results: 1 - 10 of 304007 matches for " Purificación Salmerón-Vílchez "
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Influye el uso de estrategias metacognitivas sobre el potencial creativo?
Calixto Gutierrez-Braojos,Ana Martín Romera,José Reinaldo Martínez-Fernández,Purificación Salmerón-Vílchez
Revista de Psicología y Educación , 2012,
Abstract: Desde una aproximación cognitiva al estudio de la creatividad, se ha defendido relaciones significativas entre las estrategias metacognitivas y la creatividad. Sin embargo, los estudios que analizan dichas relaciones son escasos, y el cuerpo de investigaciones empíricas ofrece conclusiones controvertidas. Esta trabajo forma parte un estudio más amplío que comprende el análisis de relaciones entre factores personológicos, cognitivos y la creatividad. En concreto, el presente trabajo tiene por objetivo de estudio testear un modelo teórico sobre las relaciones entre las estrategias metacognitivas y la creatividad mediante modelización con ecuaciones estructurales en estudiantes espa oles universitarios. Los participantes fueron 197 estudiantes matriculados en cuarto curso de la licenciatura de Psicopedagogía. Su participación fue anónima y voluntaria. Dos instrumentos fueron utilizados para la obtención de datos en este estudio: i) La Escala de Estrategias de Aprendizaje (ACRA) de Román y Gallego, (2001) para la medida del constructo estrategias metacognitivas y; ii) El Test de Inteligencia Creativa (CREA) de Corbalán et al., (2003) para la medida del potencial creatividad. Los resultados del estudio muestran una contribución positiva y significativa de las estrategias metacognitivas a la creatividad.
Association between angiogenesis soluble factors and disease progression markers in chronic hepatitis C patients Asociación entre factores angiogénicos solubles y marcadores de progresión de la enfermedad en pacientes con hepatitis crónica C
X. Salcedo Mora,P. Sanz-Cameno,J. Medina,S. Martín-Vílchez
Revista Espa?ola de Enfermedades Digestivas , 2005,
Abstract: Objectives: our objectives were to compare angiogenesis soluble factor (ASF) levels in chronic hepatitis C (CHC) patients and healthy individuals, and to investigate potential associations between ASF levels and both histological and biochemical markers of disease progression. Method: thirty-six patients (69% males) positive for HCV-RNA by PCR analysis were included in the study. All patients underwent liver biopsy before treatment. Serum levels of vascular endothelial growth factor (VEGF), soluble Flt-1 and Flk-1 receptors, placental growth factor (PlGF), angiopoietin-2 (Ang-2) and soluble Tie-2 receptor were determined by ELISA. Fifteen healthy subjects were used as controls. Results: in comparison to healthy individuals, CHC patients showed significantly increased serum levels of proangiogenic factors PlGF (22 ± 5 vs. 18 ± 8 pg/ml; p < 0.05), Ang-2 (1265 ± 385 vs. 833 ± 346 pg/ml; p < 0.005) and sFlt-1 (95 ± 22 vs. 72 ± 14 pg/ml; p < 0.0001). Interestingly, in CHC patients serum levels of VEGF and Tie-2 correlated with grade of inflammation, PlGF correlated with stage of fibrosis, and Flt-1 and Flk-1 correlated with serum transaminase levels (p < 0.05 in all cases). Conclusions: CHC patients showed increased serum levels of ASF, and a significant correlation was shown between serum levels of selected ASFs and grade of inflammation, stage of fibrosis, and transaminase levels. Objetivos: el objetivo fue comparar los niveles de los factores solubles de angiogenesis (FSA) en pacientes con hepatitis crónica C (HCC) con individuos sanos, e investigar la asociación entre los niveles de FSA y los marcadores histológicos y bioquímicos de la enfermedad. Método: treinta y seis pacientes (69,4% hombres) positivos para el ARN-VHC fueron incluidos; a todos se les realizó biopsia hepática antes del tratamiento. Los niveles séricos del factor de crecimiento endotelial vascular (VEGF), de la forma soluble de sus receptores Flt-1 y Flk-1, del factor de crecimiento placentario (PlGF), de la angiopoyetina-2 (Ang-2) y de la forma soluble de su receptor Tie-2 fueron determinados por ELISA. Se analizaron también 15 controles sanos. Resultados: al comparar los pacientes con HCC y los controles se observó una elevación significativa en los niveles de PlGF (22 ± 5 vs. 18 ± 8 pg/ml; p < 0,05), Ang-2 (1265 ± 385 vs. 833 ± 346 pg/ml; p < 0,005) y sFlt-1 (95 ± 22 vs. 72 ± 14 pg/ml; p < 0,0001). Se observó una correlación entre el VEGF y el Tie-2 con el grado de inflamación; entre PlGF y el estadio de la fibrosis; y entre Flt-1 y Flk-1 y los niveles de transaminasas (p < 0,05 en t
Efectividad del coaching en los procesos de mejora de gestión de empresas
María Dolores Vidal-Salazar,Eulogio Cordón-Pozo,Vera Ferrón-Vílchez
Universia Business Review , 2011,
Abstract: En el actual contexto empresarial, las prácticas dirigidas a la formación y desarrollo del personal constituyen una herramienta clave para los gerentes. Este trabajo analiza la eficacia de una novedosa técnica relacionada con la capacitación y desarrollo personal: el coaching. Utilizando una muestra de 40 Pymes, se analizan los efectos que produce la aplicación del coaching ejecutivo a fin de analizar su impacto en la implantación de procesos de mejora dentro de las empresas.
Association between angiogenesis soluble factors and disease progression markers in chronic hepatitis C patients
Salcedo Mora,X.; Sanz-Cameno,P.; Medina,J.; Martín-Vílchez,S.; García-Buey,L.; Borque,M. J.; Moreno-Otero,R.;
Revista Espa?ola de Enfermedades Digestivas , 2005, DOI: 10.4321/S1130-01082005001000003
Abstract: objectives: our objectives were to compare angiogenesis soluble factor (asf) levels in chronic hepatitis c (chc) patients and healthy individuals, and to investigate potential associations between asf levels and both histological and biochemical markers of disease progression. method: thirty-six patients (69% males) positive for hcv-rna by pcr analysis were included in the study. all patients underwent liver biopsy before treatment. serum levels of vascular endothelial growth factor (vegf), soluble flt-1 and flk-1 receptors, placental growth factor (plgf), angiopoietin-2 (ang-2) and soluble tie-2 receptor were determined by elisa. fifteen healthy subjects were used as controls. results: in comparison to healthy individuals, chc patients showed significantly increased serum levels of proangiogenic factors plgf (22 ± 5 vs. 18 ± 8 pg/ml; p < 0.05), ang-2 (1265 ± 385 vs. 833 ± 346 pg/ml; p < 0.005) and sflt-1 (95 ± 22 vs. 72 ± 14 pg/ml; p < 0.0001). interestingly, in chc patients serum levels of vegf and tie-2 correlated with grade of inflammation, plgf correlated with stage of fibrosis, and flt-1 and flk-1 correlated with serum transaminase levels (p < 0.05 in all cases). conclusions: chc patients showed increased serum levels of asf, and a significant correlation was shown between serum levels of selected asfs and grade of inflammation, stage of fibrosis, and transaminase levels.
La suplementación con hierro y el aumento del estrés oxidativo en el embarazo: una paradoja poco discutida
Calderón-Vélez,Juan Camilo;
Revista Colombiana de Obstetricia y Ginecología , 2007,
Abstract: providing iron supplement during pregnancy is a widely accepted medical practice. however, iron is involved in initiation and propagation chain reactions producing reactive oxygen species and lipid hydroperoxides, in turn playing an important role in the pathophysiology of gestational diabetes and preeclampsia. a paradox is then faced; iron supplement can reduce the risk of anaemia and anaemia-related complications but it can promote other diseases developing. such paradox is discussed and some studies are suggested which could be carried out to clarify when iron supplement may be indicated and used in the safest conditions for pregnant women.
La suplementación con hierro y el aumento del estrés oxidativo en el embarazo: una paradoja poco discutida Iron supplementation and oxidative stress in pregnancy: a little-discussed paradox
Juan Camilo Calderón-Vélez
Revista Colombiana de Obstetricia y Ginecología , 2007,
Abstract: La suplementación con hierro a las mujeres embarazadas es una recomendación ampliamente aceptada en la práctica médica. Sin embargo, el hierro participa en los fenómenos de iniciación y propagación de reacciones de generación de especies reactivas de oxígeno e hidroperóxidos lipídicos, los cuales juegan un papel importante en la fisiopatología de enfermedades como diabetes gestacional y preeclampsia. Aparece una paradoja: suplementar con hierro disminuye el riesgo de anemia y complicaciones, pero esta podría favorecer el desarrollo de otras enfermedades. Esta paradoja se discute en el texto y se sugieren estudios que se deben realizar para aclarar cuáles son las condiciones de mayor seguridad para suplementar con hierro a las mujeres gestantes. Providing iron supplement during pregnancy is a widely accepted medical practice. However, iron is involved in initiation and propagation chain reactions producing reactive oxygen species and lipid hydroperoxides, in turn playing an important role in the pathophysiology of gestational diabetes and preeclampsia. A paradox is then faced; iron supplement can reduce the risk of anaemia and anaemia-related complications but it can promote other diseases developing. Such paradox is discussed and some studies are suggested which could be carried out to clarify when iron supplement may be indicated and used in the safest conditions for pregnant women.
Angiopoietin-2 Serum Levels Improve Noninvasive Fibrosis Staging in Chronic Hepatitis C: A Fibrogenic-Angiogenic Link
ángel Hernández-Bartolomé, Rosario López-Rodríguez, Yolanda Rodríguez-Mu?oz, Samuel Martín-Vílchez, María Jesús Borque, Luisa García-Buey, Leticia González-Moreno, Yolanda Real, Ricardo Moreno-Otero, Paloma Sanz-Cameno
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0066143
Abstract: Aims Accurate liver fibrosis staging is crucial for the management of chronic hepatitis C (CHC). The invasiveness and cost burden of liver biopsy have driven the search for new noninvasive biomarkers of fibrosis. Based on the link between serum angiopoietin-1 and 2 levels and CHC progression, we aimed to determine the value of these angiogenic factors as noninvasive biomarkers of liver fibrosis. Methods Serum levels of angiopoietin-1 and -2 were measured by ELISA in 108 CHC patients who underwent pretreatment liver biopsy. The correlation between angiopoietins and clinical and demographic variables with liver fibrosis was analyzed by univariate regression. Significant factors were then subjected to multivariate analysis, from which we constructed a novel noninvasive liver fibrosis index (AngioScore), whose performance was validated in an independent series of 71 CHC patients. The accuracy of this model was compared with other documented fibrosis algorithms by De Long test. Results Angiopoietins correlated significantly with hepatic fibrosis; however, only angiopoietin-2 was retained in the final model, which also included age, platelets, AST, INR, and GGT. The model was validated and behaved considerably better than other fibrosis indices in discriminating all, significant, moderate and severe liver fibrosis (0.886, 0.920, 0.923). Using clinically relevant cutoffs, we classified CHC patients by discarding significant fibrosis and diagnosing moderate and severe fibrosis with greater accuracy, sensitivity, and specificity. Conclusions Our novel noninvasive liver fibrosis model, based on serum angiopoietin-2 levels, outperforms other indices and should help substantially in managing CHC and monitoring long-term follow-up prognosis.
Middle Permian crinoids (Echinodermata, Crinoidea) from Cerros Los Monos, Caborca, Sonora, Mexico and paleogeographic considerations
Buitrón-Sánchez, Blanca E.;Almazán-Vázquez, Emilio;Vachard, Daniel;
Revista mexicana de ciencias geológicas , 2007,
Abstract: crinoid columnals and pluricolumnals assigned to five species, pentaridica (col.) rothi moore and jeffords, cyclocaudex cf. c. (col.) jucundus moore and jeffords, cyclocaudex cf. c. (col.) costatus moore and jeffords, preptopremnum (col.) rugosum moore and jeffords, and heterostelechus (col.) texanus moore and jeffords, were studied from the permian beds of the monos formation which is exposed 50 kilometers west of caborca, sonora, in northwest mexico. heterostelechus (col.) texanus moore and jeffords is recorded for the first time in mexico. some crinoid samples preserve morphological features in the articular surface, allowing the species identification. the age of the fossiliferous strata was determined by the identification of fusulinids (parafusulina antimonioensis dunbar), ammonites (waagenoceras dieneri boese), and brachiopods (waagenoconcha montpelierensis (girty)) that are index fossils of wordian (middle permian) age.
The Regulatory Network of Pseudomonas aeruginosa
Edgardo Galán-Vásquez, Beatriz Luna, Agustino Martínez-Antonio
Microbial Informatics and Experimentation , 2011, DOI: 10.1186/2042-5783-1-3
Abstract: The regulatory network consists of 690 genes and 1020 regulatory interactions between their products (12% of total genes: 54% sigma and 16% of transcription factors). This complex interplay makes the third largest regulatory network of those reported in bacteria. The entire network is enriched for activating interactions and, peculiarly, self-activation seems to occur more prominent for transcription factors (TFs), which contrasts with other biological networks where self-repression is dominant. The network contains a giant component of 650 genes organized into 11 hierarchies, encompassing important biological processes, such as, biofilms formation, production of exopolysaccharide alginate and several virulence factors, and of the so-called quorum sensing regulons.The study of gene regulation in P. aeruginosa is biased towards pathogenesis and virulence processes, all of which are interconnected. The network shows power-law distribution -input degree -, and we identified the top ten global regulators, six two-element cycles, the longest paths have ten steps, six biological modules and the main motifs containing three and four elements. We think this work can provide insights for the design of further studies to cover the many gaps in knowledge of this important bacterial model, and for the design of systems strategies to combat this bacterium.Pseudomonas aeruginosa is a metabolically versatile Gram-negative bacterium, able to express a wide variety of virulence factors. These allow P. aeruginosa to grow in soil and marine habitats, as well as on plant and animal tissues. It is also a significant source of bacteraemia in burn victims, urinary-tract infections, hospital-acquired pneumonia and predominant cause of morbidity and mortality in cystic fibrosis patients [1]. All these makes P. aeruginosa the most studied bacterial model regarding the control of pathogenic determinants and the third bacterial model more studied with respect to their molecular biology -after
Variación espacial de larvas de lutjánidos y serránidos en la Plataforma de Yucatán
Falfán-Vázquez, Elsa;Ordó?ez-López, Uriel;órnelas-Roa, Margarita;
Hidrobiológica , 2008,
Abstract: the objective was to analyze the abundance and distribution of snappers and groupers in the yucatan shelf. we analyzed forty-five samples of ichthyoplankton that were taken from oceanographic research (yucatan03-a) during september 2003. superficial tows were made with a bongo net. a total of 3,963 organisms were collected, they belong to 50 fish families. three families (carangidae, gobiidae y clupeidae) represented more than 50% of the density. lutjanidae and serranidae families were within the nine most abundant families, with a total density of 713.8 ±60 org./100 m3. serranidae family is represented by species of the genus anthias, diplectrum, epinephelus, liopropoma, serranus and epinephelus fulvus, whereas lutjanidae is represented by lutjanus analis, l. campechanus, l. griseus and l. synagris. the highest density species was l. synagris, representing 28.9% of material reviewed, followed by e. fulvus, l. analis and l. campechanus. the analysis of the cluster of stations allowed identifying three oceanographic zones at a horizontal level: west, center and upwelling (in the east). the groupers larvae were distributed mainly in the center whereas snappers larvae were distributed in the east of the shelf, this suggests that the spawning of these families occurred in different parts of the shelf, avoiding in this way the competition for food in their first larval stages. the current of yucatan promotes an ekman transportation that produces an upwelling that generates an increment of phytoplankton, zooplankton and ichthyoplakton that favors the fish recruitment, a fast growth and a diminution of their larval stage.
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