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Search Results: 1 - 10 of 371 matches for " Portugal "
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Los estudios de usuarios de información: construcción de una línea de investigación y docencia en el Uruguay
Mercedes Portugal
Información, Cultura y Sociedad , 2011,
Abstract:
Uma proposta de avalia o alternativa e "autêntica" em educa o pré-escolar: o Sistema de Acompanhamento das Crian as (SAC)
GABRIELA PORTUGAL
Revista Brasileira de Educa??o , 2012,
Abstract:
Design in a critical visual culture formation
Cristina Portugal
Cultura Visual , 2011,
Abstract: Neste artigo apresenta-se uma reflex o sobre cultura visual considerando que a experiência humana a cada dia está mais exposta aos recursos visuais e entendêlos,nos tornará pessoas mais informadas e criteriosas nos processos de tomada de decis o. O Design, em fun o de sua natureza projetual pode influenciar aforma o de uma cultura visual crítica. Discute-se também. a responsabilidade do ensino de Design frente a esta nova demanda e as possibilidades de atua o desses profissionais em outros campos de saber, como por exemplo, a Educa o, objeto de estudo aqui contemplado. As discuss es realizadas neste trabalho visagerar reflex es de forma a melhorar a prática projetual, fazendo com que o design esteja mais consciente para oferecer solu es efetivas no que se refere a ambientes educacionais. ///// This paper presents a reflection on visual culture considering that the humanexperience every day is more exposed to visual and understand them,make us more informed and insightful people in decision-making processes. Design, because of its nature projectual can influence the formation of a critical visual culture. We also discuss the responsibility of the teaching of Design before this new demand and the opportunities for these professionals to action in other fields of knowledge, such as Education, object of study included here. The discussions in this paper aims generate ideas to improve design practice, making the design is more conscious to offer effective solutions with regard to educational environments.
Evaluation of molecular descriptors for antitumor drugs with respect to noncovalent binding to DNA and antiproliferative activity
Portugal José
BMC Pharmacology , 2009, DOI: 10.1186/1471-2210-9-11
Abstract: Background Small molecules that bind reversibly to DNA are among the antitumor drugs currently used in chemotherapy. In the pursuit of a more rational approach to cancer chemotherapy based upon these molecules, it is necessary to exploit the interdependency between DNA-binding affinity, sequence selectivity and cytotoxicity. For drugs binding noncovalently to DNA, it is worth exploring whether molecular descriptors, such as their molecular weight or the number of potential hydrogen acceptors/donors, can account for their DNA-binding affinity and cytotoxicity. Results Fifteen antitumor agents, which are in clinical use or being evaluated as part of the National Cancer Institute's drug screening effort, were analyzed in silico to assess the contribution of various molecular descriptors to their DNA-binding affinity, and the capacity of the descriptors and DNA-binding constants for predicting cell cytotoxicity. Equations to predict drug-DNA binding constants and growth-inhibitory concentrations were obtained by multiple regression following rigorous statistical procedures. Conclusion For drugs binding reversibly to DNA, both their strength of binding and their cytoxicity are fairly predicted from molecular descriptors by using multiple regression methods. The equations derived may be useful for rational drug design. The results obtained agree with that compounds more active across the National Cancer Institute's 60-cell line data set tend to have common structural features.
An Algorithm to Simplify Tensor Expressions
Renato Portugal
Physics , 1998, DOI: 10.1016/S0010-4655(98)00117-9
Abstract: The problem of simplifying tensor expressions is addressed in two parts. The first part presents an algorithm designed to put tensor expressions into a canonical form, taking into account the symmetries with respect to index permutations and the renaming of dummy indices. The tensor indices are split into classes and a natural place for them is defined. The canonical form is the closest configuration to the natural configuration. In the second part, the Groebner basis method is used to simplify tensor expressions which obey the linear identities that come from cyclic symmetries (or more general tensor identities, including non-linear identities). The algorithm is suitable for implementation in general purpose computer algebra systems. Some timings of an experimental implementation over the Riemann package are shown.
La comunicación desde el acto intencional: Una mirada para estudiar la ciudad
Cornejo Portugal, Inés;
Andamios , 2004,
Abstract: this paper examines some of the most important contributions for the studies on communication and culture, of the academic debate on the reception and production of meaning between james curran and david morley. its purpose is to suggest the relevance of taking some theoretical steps to approach fragments of the city from the point of view of individual experience. in this sense, the author plead for the continuous collaboration and interchange between social sciences, in terms of categories, common theories, concepts, etc. and for an hermeneutic-interpretative position, in order to lighten the fragment of life which is to be studied
Role of global and local strangeness neutrality in an inhomogeneous freeze-out approach to relativistic heavy ion collisions
Zschiesche, D.;Portugal, L.;
Brazilian Journal of Physics , 2007, DOI: 10.1590/S0103-97332007000100015
Abstract: an inhomogeneous decoupling surface of hadrons produced in relativistic heavy-ion collisions may occur, if the expanding hot and dense matter passes through a first order phase transition. we show that due to the non-linear dependence of the particle densities on the temperature and baryon-chemical potential such inhomogeneities should be visible even in the integrated, inclusive abundances. we analyze experimental data from pb+pb collisions at cern-sps and au+au collisions at bnl-rhic to determine the amplitude of inhomogeneities and the role of local and global strangeness neutrality.
Inhomogeneities in the freeze-out of relativistic heavy-ion collisions
Zschiesche, Detlef;Portugal, Licinio;
Brazilian Journal of Physics , 2007, DOI: 10.1590/S0103-97332007000500011
Abstract: an inhomogeneous decoupling surface of hadrons produced in relativistic heavy-ion collisions may occur, if the expanding hot and dense matter passes through a first order phase transition. we show that due to the non-linear dependence of the particle densities on the temperature and baryon-chemical potential such inhomogeneities should be visible even in the integrated, inclusive abundances. we analyze experimental data from pb+pb collisions at cern-sps and au+au collisions at bnl-rhic to determine the amplitude of inhomogeneities and the role of local and global strangeness neutrality.
The role of local and global strangeness neutrality at the inhomogeneous freeze-out in relativistic heavy ion collisions
Zschiesche, Detlef;Portugal, Licinio;
Brazilian Journal of Physics , 2007, DOI: 10.1590/S0103-97332007000600019
Abstract: the decoupling surface in relativistic heavy-ion collisions may not be homogeneous. rather, inhomogeneities should form when a rapid transition from high to low entropy density occurs. we analyze the hadron "chemistry" from high-energy heavy-ion reactions for the presence of such density inhomogeneities. we show that due to the non-linear dependence of the particle densities on the temperature and baryon-chemical potential such inhomogeneities should be visible even in the integrated, inclusive abundances. we analyze experimental data from pb+pb collisions at cern-sps and au+au collisions at bnl-rhic to determine the amplitude of inhomogeneities and the role of local and global strangeness neutrality.
Particle ratio fluctuations and isobaric ensemble for chemical freeze-out scenario
Portugal, Licinio L. S.;
Brazilian Journal of Physics , 2004, DOI: 10.1590/S0103-97332004000200042
Abstract: in this work, we study the behavior of event-by-event distribution of particle ratios in gran canonical and isobaric ensemble.we show that the experimental value of the width in the k/p ratio distribution is much wider than that given by a unique grand canonical ensemble or isobaric ensembe and maybe a mixture is required.
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