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Search Results: 1 - 10 of 4517 matches for " Poh Kuan Chong "
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Proteome-Wide Profiling of the MCF10AT Breast Cancer Progression Model
Lee Yee Choong,Simin Lim,Poh Kuan Chong,Chow Yin Wong,Nilesh Shah,Yoon Pin Lim
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0011030
Abstract: Mapping the expression changes during breast cancer development should facilitate basic and translational research that will eventually improve our understanding and clinical management of cancer. However, most studies in this area are challenged by genetic and environmental heterogeneities associated with cancer.
S3: School Zone Safety System Based on Wireless Sensor Network
Seong-eun Yoo,Poh Kit Chong,Daeyoung Kim
Sensors , 2009, DOI: 10.3390/s90805968
Abstract: School zones are areas near schools that have lower speed limits and where illegally parked vehicles pose a threat to school children by obstructing them from the view of drivers. However, these laws are regularly flouted. Thus, we propose a novel wireless sensor network application called School zone Safety System (S3) to help regulate the speed limit and to prevent illegal parking in school zones. S3 detects illegally parked vehicles, and warns the driver and records the license plate number. To reduce the traveling speed of vehicles in a school zone, S3 measures the speed of vehicles and displays the speed to the driver via an LED display, and also captures the image of the speeding vehicle with a speed camera. We developed a state machine based vehicle detection algorithm for S3. From extensive experiments in our testbeds and data from a real school zone, it is shown that the system can detect all kinds of vehicles, and has an accuracy of over 95% for speed measurement. We modeled the battery life time of a sensor node and validated the model with a downscaled measurement; we estimate the battery life time to be over 2 years. We have deployed S3 in 15 school zones in 2007, and we have demonstrated the robustness of S3 by operating them for over 1 year.
Multiple UWB Emitters DOA Estimation Employing Time Hopping Spread Spectrum
Joni Polili Lie;Boon Poh Ng;Chong Meng S. See
PIER , 2008, DOI: 10.2528/PIER07091303
Abstract: In this paper, UWB Direction of Arrival (DoA) estimation using channelization receiver architecture proposed in [1] is extended to cover the case of multiple UWB emitters employing Time Hopping Spread Spectrum (TH-SS) multiple access technique. The DoA estimation is based on the spectral lines extracted from the channelizer. When considering the multiple-emitter case, these spectral lines are dependent on the hopping sequences assigned to the emitters (as derived in [2]). The principle behind the proposed method is to set the channelizer's frequencies at which only the spectral lines from the desired UWB emitter are present while those from the other emitters are absent. This requires a proper design of the hopping sequences that govern the transmission of all emitters. First, an additive white Gaussian noise channel is considered to demonstrate the fundamental principle. Then, the estimation in a realistic multipath channel is addressed. Simulation results show that the direction finding function successfully indicates the DoA of the desired signal when the channelizer's frequencies are set for the detection of that signal.
Cross Neutralization of Afro-Asian Cobra and Asian Krait Venoms by a Thai Polyvalent Snake Antivenom (Neuro Polyvalent Snake Antivenom)
Poh Kuan Leong,Si Mui Sim,Shin Yee Fung,Khomvilai Sumana,Visith Sitprija,Nget Hong Tan
PLOS Neglected Tropical Diseases , 2012, DOI: 10.1371/journal.pntd.0001672
Abstract: Background Snake envenomation is a serious public health threat in the rural areas of Asian and African countries. To date, the only proven treatment for snake envenomation is antivenom therapy. Cross-neutralization of heterologous venoms by antivenom raised against venoms of closely related species has been reported. The present study examined the cross neutralizing potential of a newly developed polyvalent antivenom, termed Neuro Polyvalent Snake Antivenom (NPAV). NPAV was produced by immunization against 4 Thai elapid venoms. Principal Findings In vitro neutralization study using mice showed that NPAV was able to neutralize effectively the lethality of venoms of most common Asiatic cobras (Naja spp.), Ophiophagus hannah and kraits (Bungarus spp.) from Southeast Asia, but only moderately to weakly effective against venoms of Naja from India subcontinent and Africa. Studies with several venoms showed that the in vivo neutralization potency of the NPAV was comparable to the in vitro neutralization potency. NPAV could also fully protect against N. sputatrix venom-induced cardio-respiratory depressant and neuromuscular blocking effects in anesthetized rats, demonstrating that the NPAV could neutralize most of the major lethal toxins in the Naja venom. Conclusions/Significance The newly developed polyvalent antivenom NPAV may find potential application in the treatment of elapid bites in Southeast Asia, especially Malaysia, a neighboring nation of Thailand. Nevertheless, the applicability of NPAV in the treatment of cobra and krait envenomations in Southeast Asian victims needs to be confirmed by clinical trials. The cross-neutralization results may contribute to the design of broad-spectrum polyvalent antivenom.
When a Glue Sniffer Turns Weak  [PDF]
Poh Juliana, Puneet Seth
International Journal of Clinical Medicine (IJCM) , 2012, DOI: 10.4236/ijcm.2012.37A135

Toluene inhalation can result in electrolyte and acid-base derangements and should be considered in the differential diagnosis of young patients with unexplained hypokalaemia and normal anion gap metabolic acidosis. This case serves to illustrate the abnormalities and heighten awareness among emergency physicians who may not have laboratory results on hand when evaluating causes of limb weakness.

Solving Assembly Line Balancing Problem using Genetic Algorithm with Heuristics-Treated Initial Population
Kuan Eng Chong,Mohamed K. Omar,Nooh Abu Bakar
Lecture Notes in Engineering and Computer Science , 2008,
Radio Controlled “3D Aerobatic Airplanes” as Basis for Fixed-Wing UAVs with VTOL Capability  [PDF]
Chung-How Poh, Chung-Kiak Poh
Open Journal of Applied Sciences (OJAppS) , 2014, DOI: 10.4236/ojapps.2014.412050
Abstract: There are fundamental performance compromises between rotary-wing and fixed-wing UAVs. The general solution to address this well-known problem is the design of a platform with some degree of reconfigurable airframes. For critical missions (civilian or military), it is imperative that mechanical complexity is kept to a minimum to help achieve mission success. This work proposes that the tried-and-true radio controlled (RC) aerobatic airplanes can be implemented as basis for fixed-wing UAVs having both speed and vertical takeoff and landing (VTOL) capabilities. These powerful and highly maneuverable airplanes have non-rotatable nacelles, yet capable of deep stall maneuvers. The power requirements for VTOL and level flight of an aerobatic RC airplane are evaluated and they are compared to those of a RC helicopter of similar flying weight. This work provides quantitative validation that commercially available RC aerobatic airplanes can serve as platform to build VTOL capable fixed-wing UAVs that are agile, cost effective, reliable and easy maintenance.
Concept of Spinsonde for Multi-Cycle Measurement of Vertical Wind Profile of Tropical Cyclones  [PDF]
Chung-Kiak Poh, Chung-How Poh
Open Journal of Applied Sciences (OJAppS) , 2015, DOI: 10.4236/ojapps.2015.54015
Abstract: Tropical cyclones and cyclogenesis are active areas of research. Chute-operated dropsondes are capable of acquiring high resolution vertical wind profile of tropical cyclones. This work proposes a chute-free vertical retardation technique (termed as spinsonde) that can accurately measure vertical wind speed profile. Unlike the expendable dropsondes, the spinsonde allows multi-cycle measurement to be performed within a single flight. Proof of principle is demonstrated via simulation and results indicate that the ground speed correlates with the wind speeds to within ±5 km·h-1. This technique reduces flying weight and increases payload capacity by eliminating bulky chutes. Maximum cruising speed (VH) achieved by the spinsonde UAV is 368 km·h-1.
PTVC-M for Ultra-Agile VTOL and 300+ km·h-1 Cruising  [PDF]
Chung-Kiak Poh, Chung-How Poh
Advances in Aerospace Science and Technology (AAST) , 2016, DOI: 10.4236/aast.2016.11005
Abstract: There remains a need to develop improved VTOL techniques that are cost-effective and with minimum compromise on cruising flight performance for fixed-wing aircraft. This work proposes an elegant VTOL control method known as PTVC-M (pitch-axis thrust vector control with moment arms) for tailsitters. The hallmark of the approach is the complete elimination of control surfaces such as elevators and rudder. Computer simulations with a 1580 mm wing span airplane reveal that the proposed technique results in authoritative control and unique maneuverability such as inverted vertical hover and stall-spin with positive climb rate. Zero-surface requirement of the PTVC-M virtually eliminates performance tradeoffs between VTOL and high-speed flight. In this proof-of-concept study, the VTOL-capable aircraft achieves a VH of 360 km·h-1 at near sea-level. The proposed technique will benefit a broad range of applications including high-performance spinsonde that can directly measure 10-m surface wind, tropical cyclone research, and possibly serving as the cornerstone for the next-generation sport aerobatics.
Journey to the Typhoon  [PDF]
Chung-Kiak Poh, Chung-How Poh
Advances in Aerospace Science and Technology (AAST) , 2016, DOI: 10.4236/aast.2016.11003
Abstract: Application of UAVs (unmanned aerial vehicles) for tropical cyclone missions is an emerging area of research and recent advances include the concept of spinsonde for multi-cycle measurement of vertical wind profile within the storm. This work proposes the design of a typhoon UAV as part of a cost-effective approach for acquiring atmospheric data to improve prediction and refine models. Land- and carrier-based flight schemes are proposed in this study and computer simulations are carried out to investigate the flight performance. Results suggest that the UAV achieves a maximum cruising speed in excess of 350 km·h-1 with excellent spinsonde performance. Furthermore, the UAV is capable of performing high-alpha maneuvers as well as vertical landing, thus rendering it suitable for space-efficient operation whether on land or aircraft carrier.
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