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Search Results: 1 - 10 of 2119 matches for " Pietro Capone "
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Celiac disease: Alternatives to a gluten free diet
Fabiana Zingone,Pietro Capone,Carolina Ciacci
World Journal of Gastrointestinal Pharmacology and Therapeutics , 2010,
Abstract: Celiac disease is a chronic inflammatory disorder of the small intestine caused by the ingestion of gluten or related rye and barley proteins. At present, the only available treatment is a strict gluten-exclusion diet. However, recent understanding of the molecular basis for this disorder has improved and enabled the identification of targets for new therapies. This article aims to critically summarize these recent studies.
Prevalence of functional dyspepsia and its subgroups in patients with eating disorders
Antonella Santonicola,Monica Siniscalchi,Pietro Capone,Serena Gallotta
World Journal of Gastroenterology , 2012, DOI: 10.3748/wjg.v18.i32.4379
Abstract: AIM: To study the prevalence of functional dyspepsia (FD) (Rome III criteria) across eating disorders (ED), obese patients, constitutional thinner and healthy volunteers. METHODS: Twenty patients affected by anorexia nervosa, 6 affected by bulimia nervosa, 10 affected by ED not otherwise specified according to diagnostic and statistical manual of mental disorders, 4th edition, nine constitutional thinner subjects and, thirty-two obese patients were recruited from an outpatients clinic devoted to eating behavior disorders. Twenty-two healthy volunteers matched for age and gender were enrolled as healthy controls. All participants underwent a careful clinical examination. Demographic and anthropometric characteristics were obtained from a structured questionnaires. The presence of FD and, its subgroups, epigastric pain syndrome and postprandial distress syndrome (PDS) were diagnosed according to Rome III criteria. The intensity-frequency score of broader dyspeptic symptoms such as early satiety, epigastric fullness, epigastric pain, epigastric burning, epigastric pressure, belching, nausea and vomiting were studied by a standardized questionnaire (0-6). Analysis of variance and post-hoc Sheffè tests were used for comparisons. RESULTS: 90% of patients affected by anorexia nervosa, 83.3% of patients affected by bulimia nervosa, 90% of patients affected by ED not otherwise specified, 55.6% of constitutionally thin subjects and 18.2% healthy volunteers met the Postprandial Distress Syndrome Criteria (χ2, P < 0.001). Only one bulimic patient met the epigastric pain syndrome diagnosis. Postprandial fullness intensity-frequency score was significantly higher in anorexia nervosa, bulimia nervosa and ED not otherwise specified groups compared to the score calculated in the constitutional thinner group (4.15 ± 2.08 vs 1.44 ± 2.35, P = 0.003; 5.00 ± 2.45 vs 1.44 ± 2.35, P = 0.003; 4.10 ± 2.23 vs 1.44 ± 2.35, P = 0.002, respectively), the obese group (4.15 ± 2.08 vs 0.00 ± 0.00, P < 0.001; 5.00 ± 2.45 vs 0.00 ± 0.00, P < 0.001; 4.10 ± 2.23 vs 0.00 ± 0.00, P < 0.001, respectively) and healthy volunteers (4.15 ± 2.08 vs 0.36 ± 0.79, P < 0.001; 5.00 ± 2.45 vs 0.36 ± 0.79, P < 0.001; 4.10 ± 2.23 vs 0.36 ± 0.79, P < 0.001, respectively). Early satiety intensity-frequency score was prominent in anorectic patients compared to bulimic patients (3.85 ± 2.23 vs 1.17 ± 1.83, P = 0.015), obese patients (3.85 ± 2.23 vs 0.00 ± 0.00, P < 0.001) and healthy volunteers (3.85 ± 2.23 vs 0.05 ± 0.21, P < 0.001). Nausea and epigastric pressure were increased in bulimic and ED not otherwis
Electronic correlation assisted ferroelectric metallic state in LiOsO$_3$
I. Lo Vecchio,G. Giovannetti,M. Autore,P. Di Pietro,A. Perucchi,J. He,K. Yamaura,M. Capone,S. Lupi
Physics , 2015,
Abstract: LiOsO$_3$ has been recently identified as the first unambiguous "ferroelectric metal", experimentally realizing a prediction from 1965 by Anderson and Blount. In this work, we investigate the metallic state in LiOsO$_3$ by means of infrared spectroscopy supplemented by Density Functional Theory and Dynamical Mean Field Theory calculations. Our measurements and theoretical calculations clearly show that LiOsO$_3$ is a very bad metal with a small quasiparticle weight, close to a Mott-Hubbard localization transition. The agreement between experiments and theory allows us to ascribe all the relevant features in the optical conductivity to strong electron-electron correlations within the $t_{2g}$ manifold of the osmium atoms.
Speed of Adjustment and Infraday/Intraday Volatility in the Italian Stock and Futures Markets  [PDF]
Pietro Gottardo
Modern Economy (ME) , 2011, DOI: 10.4236/me.2011.25082
Abstract: We estimate the speed of adjustment of prices to value changes in the Italian stock and futures markets using variances in different return intervals. The paper presents evidence that an assumption of linearity for the relationship volatility-time is untenable when intraday and infraday data are used jointly. Prices adjust to new information within three days, but the process is complex with evidence of overshooting and divergent movements in the smaller return intervals. Firms behave differently according to their inclusion or exclusion from the MIB30 index. The speed of adjustment is strongly related to firm-specific characteristics and the log of capitalization explains some of the cross-sectional variability in the adjustment coefficients for most of the return intervals.
Coronary sinus reentrant tachycardia after atrial fibrillation ablation: From bad to worse  [PDF]
Pietro Turco
World Journal of Cardiovascular Diseases (WJCD) , 2014, DOI: 10.4236/wjcd.2014.42006
Abstract: Herein we present a case of atrial tachycardia as a sequel of AF ablations. A 42-year-old man was admitted to our department because of a very symptomatic tachycardia. The patient, because of paroxysmal AF and typical atrial flutter, had been already submitted (three times) to ablation procedures in both left (pulmonary vein insulation) and right atria (cavo-tricuspidal isthmus). During the electrophysiological study, a huge and very fast atrial tachycardia was induced: 230 ms cycle length, 1/1 atrio-ventricular conduction with the ventricular rate of 260 bpm, complete left bundle branch block, and clinically recognized by the patient. Four minutes later, a 2/1 AV conduction without branch block permitted mapping and ablation. A high-density mapping around isthmus and coronary sinus (CS) was performed. The analysis of the chronological activation clearly showed a circuit propagation around the CS ostium with a very slow conduction in the anterior zone enlightened by the tight color progression, and counterclockwise activation of the right atrium lateral wall. In anterior zone of CS ostium diastolic fragmented electrograms were detected. After preventing his position localization, radiofrequency delivering (35 W) was effective to interrupt the arrhythmia in 3 seconds. Energy delivering was continued to anchor the lesion to the inferior vena cava. Confirmation of successful ablation was determined by unsuccessful attempts at reinduction of the arrhythmia, in basal state and during infusion of isoproterenol.
A Theoretical Overview of Bioresponse to Magnetic Fields on the Earth’s Surface  [PDF]
Pietro Volpe
International Journal of Geosciences (IJG) , 2014, DOI: 10.4236/ijg.2014.510097
Abstract: This survey points to the mechanisms of bioresponse caused by magnetic fields (MFs), paying attention to their action not only on ions, molecules and macromolecules, but also on cells, tissues and organisms. The significance of findings concerning the MF-dependence of cell proliferation, necrosis or apoptosis was judged by comparing the results obtained in a solenoid, where an MF can be added to the geomagnetic field (GMF), with those obtained in a magnetically shielded room, where the MFs can be attenuated or null. This comparative criterion was particularly appropriate when the differences detectable between the data provided by experimental samples and the data provided by control samples were rather small, as observed in estimating the MF-influence on total DNA replication, RNA transcription and polypeptide translation. The MF-induced inhibition of apoptosis was considered as a risk potentially leading to accumulation of cancer cells. The analysis also surveyed the MF-dependence of the interactions between host animal cells and infecting bacteria. In relation to studies on the origin and adaptation of life on the Earth, theoretical insights paving the way to elucidating the MF-interactions with biostructures and biosystems of different orders of organization evaluated the possible involvement of the so-called “biological windows”. Analogously to what is known for ionizing radiations, the efficiency of the applied MFs appeared to depend on the complexity of their biological targets.
The Outrageous Discourse of Psychoanalysis for Present-Day Academic Institutions  [PDF]
Pietro Barbetta
Open Journal of Social Sciences (JSS) , 2015, DOI: 10.4236/jss.2015.33021
Abstract: In the following essay I’m going to take a radical position concerning the tendency to eliminate psychoanalysis from the European Academic field and the failure of psychoanalysts and relational therapists to defend psychoanalysis from such aggression. My question is why in Italy—just to make a local example, which I am involved in—different kinds of psychoanalytical traditions are not able to defend themselves from this attack while in France, for another example, all the different branches of relational therapies have been able to unite in making a common effort to take a position for psychoanalysis. One of the main problems, in my opinion, concerns the constitutive marginality of psychoanalysis in relation to Academic Institutions. In my way of writing, I will use psychoanalysis, with “P” in capital character, when referred to Academia, and psychoanalysis, with no capital character, when referred to clinical practice.
The Unexpected Existence of Coding and Non-Coding Fragments along the Eukaryotic Gene  [PDF]
Pietro Volpe
Advances in Biological Chemistry (ABC) , 2015, DOI: 10.4236/abc.2015.52009
Abstract: The pathways leading to synthesis and post-synthetic modification of DNA employed methionine as donor of atoms: the carbon that came from its –CH3 served for DNA replication and repair either in bacteria or humans; its entire –CH3 served instead for building N6-methyladenine and 5-methylcytosine on bacterial DNA and 5-methylcytosine alone on human DNA. In humans, although a slight extra-S asymmetric methylation appeared de novo yielding on parental DNA 5’-m5CpC-3’/ 3’-GpG-5’, 5’-m5CpT-3’/3’-GpA-5’ and 5’-m5CpA-3’/3’-GpT-5’ monomethylated dinucleotide pairs, a heavy symmetric methylation involved in S semiconservatively newly made DNA to guarantee genetic maintenance of –CH3 in 5’-m5CpG-3’/3’-Gpm5C-5’ dimethylated dinucleotide pairs. In this framework, an inverse correlation was found between bulk genomic DNA methylation occurring in S and bulk polyA-containing pre-mRNA transcription taking place in G1 and G2. Thus, probes of 1 × 106 Daltons (constructed using sheared by sonication newly made methylated DNA filaments) revealed a modular organization in genes: after the hypermethylated promoter, they exhibited an alternation of unmethylated coding and methylated uncoding sequences. This encouraged the search for a language that genes regulated by methylation should have in common. An initial deciphering of restriction minimaps with hypomethylatable exons vs. hypermethylatable promoters and introns was improved when the bisulfite technique allowed a direct sequencing of m5C. In lymphocytes, where the transglutaminase gene is inactive, its promoter exhibited two fully methylated CpG-rich domains at 5’ and one fully unmethylated CpG-rich domain at 3’, including the site +1 and a 5’-UTR. At variance, in HUVEC cells, where the transglutaminase gene is active, in the first CpG-rich domain of promoter few doublets lost their –CH3. Such an inverse correlation suggested new hypotheses especially in connection with repair-modification: UV radiation would cause demethylation in given loci of a promoter by chance, whilst even a partial demethylation in this promoter would be able to resume a previously silent pre-mRNA transcription.
Archeologia Urbana. Rappresentare l’incertezza: gli scavi archeologici di Piazza Bovio a Napoli Urban Archaeology. How to represent uncertainty: the archaeological excavations of Piazza Bovio in Naples
Mara Capone
DISEGNARECON , 2011,
Abstract: L’evoluzione dei sistemi di comunicazione ha favorito la sperimentazione di nuove modalità di fruizione dei beni culturali attraverso l’uso di media digitali. Nel caso dei reperti archeologici, il gap comunicativo connesso alla mancata integrità del segno, rende indispensabile la realizzazione di un progetto di comunicazione che sia in grado di fornire tutte le informazioni integrative affinché il reperto possa comunicare il significato culturale di cui è portatore. L’utilizzo di modelli 3D consente di realizzare gli interventi di ricostruzione su una copia digitale, aprendo nuove prospettive nell’ambito della ricerca archeologica e ponendo nuove problematiche relative all’individuazione di un codice adeguato a rappresentare l’incertezza. Gli scavi archeologici di Piazza Bovio a Napoli sono stati il preteso per raccontare la storia del luogo sperimentando l’uso integrato dei modelli all’interno della sequenza filmica. The evolution of communication systems has led to experimentation with new ways to enjoying cultural heritage using digital media. Archaeological finding are only a piece of matter with high ambiguity level and so we have to do something to resolve this ambiguity. The use of 3D models can achieve the reconstruction of a digital copy, opening new perspectives in the context of archaeological research and posing new problems related to the identification of an appropriate code to represent the uncertainty. The choice of a particularly complex case study, the archaeological excavation of Piazza Bovio in Naples, allowed us to address a number of unusual issues and we have tried to tell the story of the place testing the use of 3D models in a film sequence.
La proliferazione degli Albi dei professionisti per le stime indebolisce il prestigio e la funzione dell'Ordine professionale
E. Capone
Aestimum , 1995,
Abstract:
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