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Search Results: 1 - 10 of 10928 matches for " Pierre Jais "
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Phrenic Nerve Injury After Catheter Ablation of Atrial Fibrillation
Frederic Sacher,Pierre Jais,Kent Stephenson,Mark D O'Neill
Indian Pacing and Electrophysiology Journal , 2007,
Abstract: Phrenic Nerve Injury (PNI) has been well studied by cardiac surgeons. More recently it has been recognized as a potential complication of catheter ablation with a prevalence of 0.11 to 0.48 % after atrial fibrillation (AF) ablation. This review will focus on PNI after AF ablation. Anatomical studies have shown a close relationship between the right phrenic nerve and it's proximity to the superior vena cava (SVC), and the antero-inferior part of the right superior pulmonary vein (RSPV). In addition, the proximity of the left phrenic nerve to the left atrial appendage has been well established. Independent of the type of ablation catheter (4mm, 8 mm, irrigated tip, balloon) or energy source used (radiofrequency (RF), ultrasound, cryothermia, and laser); the risk of PNI exists during ablation at the critical areas listed above. Although up to thirty-one percent of patients with PNI after AF ablation remain asymptomatic, dyspnea remain the cardinal symptom and is present in all symptomatic patients. Despite the theoretical risk for significant adverse effect on functional status and quality of life, short-term outcomes from published studies appear favorable with 81% of patients with PNI having a complete recovery after 7 ± 7 months.Conclusion: Existing studies have described PNI as an uncommon but avoidable complication in patients undergoing pulmonary vein isolation for AF. Prior to ablation at the SVC, antero-inferior RSPV ostium or the left atrial appendage, pacing should be performed before energy delivery. If phrenic nerve capture is documented, energy delivery should be avoided at this site. Electrophysiologist's vigilance as well as pacing prior to ablation at high risk sites in close proximity to the phrenic nerve are the currently available tools to avoid the complication of PNI.
Classical and weak solutions for semilinear parabolic equations with Preisach hysteresis
Mathias Jais
Opuscula Mathematica , 2008,
Abstract: We consider the solvability of the semilinear parabolic differential equation $$\frac{\partial u}{\partial t}(x,t)- \Delta u(x,t) + c(x,t)u(x,t) = P(u) + \gamma (x,t)$$ in a cylinder $D=\Omega \times (0,T),$ where $P$ is a hysteresis operator of Preisach type. We show that the corresponding initial boundary value problems have unique classical solutions. We further show that using this existence and uniqueness result, one can determine the properties of the Preisach operator $P$ from overdetermined boundary data.
Molecular Size of the Bio-active Components from Haruan Channa striatus Extract
Abdul Manan Mat Jais
Journal of Applied Sciences , 2007,
Abstract: Extracts of an indigenous tropical carnivorous and air breathing fish haruan Channa striatus was shown to have antinociceptive activity in mice and the aim was to study tinvestigateto, at the molecular size of the bioactive compound(s), for isolation and identification. The aqueous portion of crude extract in chloroform-methanol 2: v/v was subjected to filtration by Millipore Ultrafree-CL low binding cellulose filter 5,000; 10,000 and 30,000 Dalton (Nominal Molecules Weight Limit or NMWL) and centrifuged for 10 min at 5,000 rpm. Series of 0, 25, 50 and 100% dilutions of the filtered solutions in distilled water were purified through preparative HPLC. The fraction collected between 1-3 min was dried under vacuum yielding 30 mg to be reconstituted in distilled water to a concentration of 0.0005, 0.005, 0.05 and 0.5 mg mL-1 in distilled water which were then used for abdominal constriction tests in mice according to method described by Mat Jais. The non-filtered, the 5,000 and 10,000 NMWL samples produced similar HPLC traces. The results indicated that the bioactive compound is less than 5,000 NMWL and finally, the fraction 1 at retention times 1 to 3 min, of the HPLC purified sample was also produced inhibition in the constriction test.
Pharmacognosy and pharmacology of Haruan (Channa striatus), a medicinal fish with wound healing properties
Abdul Manan Mat Jais
Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas , 2007,
Abstract: Haruan (Channa striatus) es un pez carnívoro, capaz de respirar aire libre, indígena de Malasia. Su carne blanca y sin espinas posee un delicado gusto que la ha hecho una opción gastronómica muy popular pero también esta considerada como un remedio natural entre pacientes post-operativos para ayudar en el proceso de cicatrización. Otras propiedades farmacológicas incluyen una potente actividad antinociceptiva del mucus que recubre las escamas de este pez así como prometedoras actividades antimicrobianas, antifúngicas y anticoagulantes. Tanto el pez criado en condiciones salvajes como el cultivado poseen las mismas características organolépticas y medicinales. Y por tanto constituye una prometedora y sostenible fuente para esta medicina tradicional. Su composición química incluye elevados niveles de aminoácidos y ácidos grasos esenciales que influencian positivamente el proceso de cicatrización pero actualmente se trabaja intensamente en la caracterización de otros bioactivos presentes sobre todo en el mucus. Todo esto o convierte en un prometedor candidato tanto como nutracéutico como producto netamente farmacéutico. Nuestro grupo trabaja intensamente en el desarrollo y comercialización de productos basados en Haruan y los ensayos clínicos ya han comenzado. Con esta revisión del estado de conocimientos acerca de esta particular droga animal espero ilustrar como el desarrollo y comercialización de producto biomédicos a partir de fuentes naturales también se puede aplicar a las drogas animales y no solo a las vegetales.
Atrial Tachycardias Arising from Ablation of Atrial Fibrillation: A Proarrhythmic Bump or an Antiarrhythmic Turn?
Ashok J. Shah,Amir Jadidi,Xingpeng Liu,Shinsuke Miyazaki,Andrei Forclaz,Isabelle Nault,Lena Rivard,Nick Linton,Olivier Xhaet,Nicolas Derval,Frederic Sacher,Pierre Bordachar,Philippe Ritter,Meleze Hocini,Pierre Jais,Michel Haissaguerre
Cardiology Research and Practice , 2010, DOI: 10.4061/2010/950763
Abstract: The occurrence of atrial tachycardias (AT) is a direct function of the volume of atrial tissue ablated in the patients with atrial fibrillation (AF). Thus, the incidence of AT is highest in persistent AF patients undergoing stepwise ablation using the strategic combination of pulmonary vein isolation, electrogram based ablation and left atrial linear ablation. Using deductive mapping strategy, AT can be divided into three clinical categories viz. the macroreentry, the focal and the newly described localized reentry all of which are amenable to catheter ablation with success rate of 95%. Perimitral, roof dependent and cavotricuspid isthmus dependent AT involve large reentrant circuits which can be successfully ablated at the left mitral isthmus, left atrial roof and tricuspid isthmus respectively. Complete bidirectional block across the sites of linear ablation is a necessary endpoint. Focal and localized reentrant AT commonly originate from but are not limited to the septum, posteroinferior left atrium, venous ostia, base of the left atrial appendage and left mitral isthmus and they respond quickly to focal ablation. AT not only represents ablation-induced proarrhythmia but also forms a bridge between AF and sinus rhythm in longstanding AF patients treated successfully with catheter ablation. 1. Introduction Atrial fibrillation (AF) is no longer a formidable rhythm since ablationists challenged this notorious arrhythmia more than a decade ago in their unprecedented quest for sinus rhythm (SR) [1]. Ablation strategies are based on clinical types of AF but nevertheless, the volume of tissue ablated to treat AF is highest for any cardiac arrhythmia described so far. Paroxysmal AF is amenable to catheter ablation with minimum atrial tissue destruction such that electrical isolation of pulmonary veins (PVs) suffices for establishing cure [2]. Persistent and longer lasting forms of AF necessitate extensive atrial tissue ablation in addition to PV isolation to restore SR [3–7]. Besides having evolved as a therapeutic option in symptomatic AF, surgical ablation has become a routine adjunct to many valvular surgeries and may be employed with surgical coronary revascularization and also as a “standalone” procedure [8, 9]. Despite improvements in ablation strategies, relatively high volume of tissue ablation is performed in AF. Together with remodeling of atria, it provides a favourable substrate for the development of sustained atrial tachycardia(s) during and after AF ablation (ATp) [4]. 2. Magnitude of ATp Burden Based on our observation and also that of
How emergency departments might alert for prehospital heat-related excess mortality?
Yann-Erick Claessens, Pierre Taupin, Gérald Kierzek, Jean-Louis Pourriat, Michel Baud, Christine Ginsburg, Jean-Philippe Jais, Eric Jougla, Bruno Riou, Jean-Fran？ois Dhainaut, Paul Landais
Critical Care , 2006, DOI: 10.1186/cc5092
Abstract: A day-to-day composite indicator was built using simple and easily obtainable variables related to patients referred to the ED during the 2003 heat-wave period. The design involved a derivation and validation study based on a real-time surveillance system of two EDs at Cochin Hospital and H？tel-Dieu Hospital, Paris, France. The participants were 99,976 adult patients registered from 1 May to 30 September during 2001, 2002 and 2003. Among these participants, 3,297, 3,580 and 3,851 patients were referred to the EDs from 3 August to 19 August for 2001, 2002 and 2003, respectively. Variables retained for the indicator were selected using the receiver operating characteristic curve methodology and polynomial regression.The indicator was composed of only three variables: the percentage of patients older than 70 years, the percentage of patients with body temperature above 39°C, and the percentage of patients admitted to or who died in the ED. The curve of the indicator with time appropriately fitted the overall mortality that occurred in the region of interest.A composite and simple index based on real-time surveillance was developed according to the profile of patients who visited the ED. It appeared suitable for determining the overall mortality in the corresponding region submitted to the 2003 heat wave. This index should help early warning of excessive mortality and monitoring the efficacy of public health interventions.Unusually high temperatures with normal relative humidity were recorded during summer 2003 in Europe [1,2], especially in France [3]. Within a few days of the onset of the heat wave, the French National Institute for Public Health and Medical Research (INSERM) reported a sharp increase in the number of heat-related deaths [4]. Three hundred excess deaths were observed on 4 August 2003. These excess deaths progressively increased until 12 August, reaching 2,000 per day, and then rapidly stopped as soon as the temperature decreased after 14 August. Cumul
Aloe vera: A valuable multifunctional cosmetic ingredient
Gauri BASMATKER,Neha JAIS,Farhat DAUD
International Journal of Medicinal and Aromatic Plants , 2011,
Abstract: The Aloe vera plant (botanical name- Aloe barbadensis Mill.) has been known and used for centuries for its health, beauty, medicinal and skin care properties. It belongs to Asphodelaceae (Liliaceae) family, and is a shrubby or arborescent, perennial, xerophytic, succulent, pea- green color plant. The use of Aloe vera has increased tremendously in the field of cosmetology and a wide variety of products contain Aloe vera in one form or other for delivering a specific activity. Aloe vera contains 75 potentially active constituents: vitamins, enzymes, minerals, sugars, lignin, saponins, salicylic acids and amino acids, which are responsible for the multifunctional activity of Aloe. Various cosmetic uses of aloe are reviewed in this article.
Bending Fuchsian representations of fundamental groups of cusped surfaces in PU(2,1)
Pierre Will
Mathematics , 2011,
Abstract: We describe a family of representations of $\pi_1(\Sigma)$ in PU(2,1), where $\Sigma$ is a hyperbolic Riemann surface with at least one deleted point. This family is obtained by a bending process associated to an ideal triangulation of $\Sigma$. We give an explicit description of this family by describing a coordinates system in the spirit of shear coordinates on the Teichm\"uller space. We identify within this family new examples of discrete, faithful and type-preserving representations of $\pi_1(\Sigma)$. In turn, we obtain a 1-parameter family of embeddings of the Teichm\"uller space of $\Sigma$ in the PU(2,1)-representation variety of $\pi_1(\Sigma)$. These results generalise to arbitrary $\Sigma$ the results obtained in a previous paper for the 1-punctured torus.
Two Generator groups acting on the complex hyperbolic plane
Pierre Will
Mathematics , 2015,
Abstract: This is an expository article about groups generated by two isometries of the complex hyperbolic plane.
Plasmon-enhanced second harmonic generation in semiconductor quantum dots close to metal nanoparticles
Pablo M. Jais,Catalina von Bilderling,Andrea V. Bragas
Papers in Physics , 2011, DOI: 10.4279/pip.030002
Abstract: We report the enhancement of the optical second harmonic signal in non-centrosymmetric semiconductor CdS quantum dots, when they are placed in close contact with isolated silver nanoparticles. The intensity enhancement is about 1000. We also show that the enhancement increases when the incoming laser frequency $omega$ is tuned toward the spectral position of the silver plasmon at $2omega$, proving that the silver nanoparticle modifies the nonlinear emission. Received: 8 March 2011, Accepted: 30 May 2011; Edited by: L. Vi a; Reviewed by: R. Gordon, Department of Electrical and Computer Engineering, University of Victoria, British Columbia, Canada; DOI: 10.4279/PIP.030002 Cite as: P. M. Jais, C. von Bilderling, A. V. Bragas, Papers in Physics 3, 030002 (2011)
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