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Search Results: 1 - 10 of 494 matches for " Pierluigi Novellis "
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Usefulness of Whole-Body Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography in Patients with Neurofibromatosis Type 1: A Systematic Review
Giorgio Treglia,Silvia Taralli,Francesco Bertagna,Marco Salsano,Barbara Muoio,Pierluigi Novellis,Maria Letizia Vita,Fabio Maggi,Alessandro Giordano
Radiology Research and Practice , 2012, DOI: 10.1155/2012/431029
Abstract: Aim. To systematically review the role of positron emission tomography (PET) with fluorine-18-fluorodeoxyglucose (FDG) in patients with neurofibromatosis type 1 (NF1). Methods. A comprehensive literature search of published studies regarding FDG-PET and PET/CT in patients with NF1 was performed. No beginning date limit and language restriction were used; the search was updated until December 2011. Only those studies or subsets in studies including whole-body FDG-PET or PET/CT scans performed in patients with NF1 were included. Results. We identified 12 studies including 352 NF1 patients. Qualitative evaluation was performed in about half of the studies and semiquantitative analysis, mainly based on different values of SUV cutoff, in the others. Most of the studies evaluated the role of FDG-PET for differentiating benign from malignant peripheral nerve sheath tumors (MPNSTs). Malignant lesions were detected with a sensitivity ranging between 100% and 89%, but with lower specificity, ranging between 100% and 72%. Moreover, FDG-PET seems to be an important imaging modality for predicting the progression to MPNST and the outcome in patients with MPNST. Two studies evaluated the role of FDG-PET in pediatric patients with NF1. Conclusions. FDG-PET and PET/CT are useful methods to identify malignant change in neurogenic tumors in NF1 and to discriminate malignant from benign neurogenic lesions. 1. Introduction Neurofibromatosis type 1 (NF1) is an autosomal dominant disease with an incidence of 1 in 2,500 to 1 in 3,000 subjects. Neurofibroma, a benign peripheral nerve sheath tumor, is the most common tumor in NF1 patients and may manifest as focal nodular, cutaneous or subcutaneous lesion, intraforaminal spinal nerve root tumor, or plexiform neurofibroma (PNF). Patients with NF1 have an increased risk of developing malignant peripheral nerve sheath tumors (MPNSTs) with a life-time risk of 8–12% [1–6]. MPNSTs usually arise from preexisting benign PNF, metastasize widely, and frequently have a poor prognosis. Therefore, differentiating between benign and malignant tumors in patients with NF1 has important prognostic and therapeutic implications, but can be difficult, especially in individuals who have multiple benign tumors. Optimal management is dependent on early and accurate histological grading and staging of the disease, but MPNSTs are often difficult to detect and may metastasize to many different sites. Pain, rapid increase in size of a neurofibroma, and the development of neurological deficit are clinical indicators of malignancy, but may also be features
Methodological Accounting Tools for the Evaluation of Intangibles Management in Research Institutions: Some Empirical Remarks  [PDF]
Pierluigi Catalfo
Journal of Service Science and Management (JSSM) , 2015, DOI: 10.4236/jssm.2015.84064
Abstract: Knowledge is primarily considered as powerful value producer. The dynamic relationship of university and society starts with the economic exploitation of research results, with the intention, on the one hand, to safeguard the equilibrium of financial resources to support academic activity on the other hand with the intention to sustain society and more specifically stakeholders’ interests. University and precisely its departmental structure are increasingly involved in the implementation and improvement of strategies focusing on technological transfer and on the activity of managing internal intangible resources. This study, after considering the logic that inspires or should inspire models for the evaluation of knowledge creation and accountability through the intangible assets of academic departments and research centres, illustrates empirically the situation concerning the diffusion of immaterial resource management tools in a relevant research area in Italy.
Orographic Effects on Extreme Rainfall at Different Durations: A Case Study in Campania Region (Southern Italy)  [PDF]
Pierluigi Furcolo, Anna Pelosi
Journal of Geoscience and Environment Protection (GEP) , 2018, DOI: 10.4236/gep.2018.611006
Abstract: Long-term probabilistic prediction of extreme rainfall at the regional scale is a significant tool in the mitigation of hydro-geological disasters: it actually provides the starting point in the design of strategic hydraulic infrastructures and emergency plans. A crucial task of regional estimation of extreme rainfall is how to include the complex effects of orographic barriers in a mathematical model for Intensity-Duration-Frequency (IDF) curves. Here, an analysis of how orography can affect extreme rainfall at different durations is presented for three orographic systems that are very relevant for hydrological risk assessment in the Campania Region in Southern Italy. Then, we introduce a power law model to link the amplification factor to the duration, thus allowing a simple and effective enhancement of the IDF model in mountainous areas.
On the rumors about the silent spring: review of the scientific evidence linking occupational and environmental pesticide exposure to endocrine disruption health effects
Cocco, Pierluigi;
Cadernos de Saúde Pública , 2002, DOI: 10.1590/S0102-311X2002000200003
Abstract: occupational exposure to some pesticides, and particularly dbcp and chlordecone, may adversely affect male fertility. however, apart from the therapeutic use of diethylstilbestrol, the threat to human reproduction posed by "endocrine disrupting" environmental contaminants has not been supported by epidemiological evidence thus far. as it concerns other endocrine effects described in experimental animals, only thyroid inhibition following occupational exposure to amitrole and mancozeb has been confirmed in humans. cancer of the breast, endometrium, ovary, prostate, testis, and thyroid are hormone-dependent, which fostered research on the potential risk associated with occupational and environmental exposure to the so-called endocrine-disrupting pesticides. the most recent studies have ruled out the hypothesis of ddt derivatives as responsible for excess risks of cancer of the reproductive organs. still, we cannot exclude a role for high level exposure to o,p'-dde, particularly in post-menopausal er+ breast cancer. on the other hand, other organochlorine pesticides and triazine herbicides require further investigation for a possible etiologic role in some hormone-dependent cancers.
Alessio Baldini, Dipingere coi colori adatti. I Malavoglia e il romanzo moderno
Pierluigi Pellini
Between , 2012,
Abstract: Nell’Introduzione a Verga moderno (Roma--‐ Bari, Laterza, 2005), Romano Luperini scrive che la fortuna di Verga si lega sempre a momenti di forte tensione teorica e anche ideale e politica . E aggiunge che un segnale del degrado culturale dell’Italia contemporanea è la tendenza a vivere la polemica letteraria come un’offesa personale . L’auspicio è duplice: da un lato una ripresa di studi non stancamente micro--‐ filologici sull’autore dei Malavoglia; dall’altro un confronto intellettuale fra studiosi che rifugga dal salamelecco accademico . Un giovane ricercatore di scuola senese (ora “cervello in fuga” in Gran Bretagna), Alessio Baldini, con una monografia che coniuga minuta explication de textes e coraggiosa generalizzazione teorica, assolve ottimamente il primo compito. Provo a incaricarmi del secondo: non lo farei, se il mio giudizio sull’importanza del libro non fosse decisamente positivo.
Tecniche della frontiera. Strategie semiotiche di controllo dello spazio urbano in Italia Borderline technique: a semiotic strategie for controlling the urban space in Italy
Pierluigi Cervelli
Galáxia , 2011,
Abstract: L’obiettivo di questo articolo è riflettere sulle pratiche di controllo urbano recentemente adottate in Italia, e in particolare nella città di Roma, indagando la gestione dello spazio pubblico in un recente quartiere periferico per la classe media. Concentrandosi sulla privatizzazione dello spazio, la costruzione delle visibilità ed il controllo dei percorsi, l’articolo si propone di descrivere alcune strategie di manipolazione della competenza delle persone che percorrono lo spazio pubblico. Strumenti e strategie di controllo sono poi messe in relazione coi provvedimenti e le ordinanze sulla sicurezza urbana recentemente emesse dal governo italiano e dalle amministrazioni cittadine per limitare la presenza di accampamenti di immigrati e tzigani rom e sinti. Utilizzando gli strumenti della semiotica strutturale, l’articolo sostiene che è possibile considerare l’organizzazione spaziale e i discorsi politici come parti di una unica strategia, reciprocamente in relazione di traduzione intersemiotica, di costruzione di un nuovo tipo di marginalità, composta da una massa di persone costrette a muoversi continuamente. Riflettendo sulle specificità di questa situazione si considerano infine le differenze con l’organizzazione dei sistemi panottici descritti da M. Foucault e la sua riflessione sul controllo e sulla sicurezza. This article aims to reflect on recent practices of urban control in Italy, and particularly in the city of Rome, investigating the handling of the public space in a new middle class suburban district. Especially focusing on spatial privatization, visibility construction and pathways control, the article tries to depict some manipulation strategies of people’s competence for moving throughout the public space. Control tools and strategies are put in relation with some urban security regulations recently adopted by Italian government and cities municipalities, in order to avoid spontaneous settlements of immigrants and roma gypsies and sinti people. Using some analytical instruments of the structural semiotic theory, the article argues that it’s possible to consider spatial organization and political speeches as parts of an intersemiotic translation process and that the goal of this process is to create a new form of urban marginality, composed by a mass of people forced to continuously move. In order to describe the specificity of this kind of situation are finally taken in consideration the differences with the panoptical organization depicted by Michel Foucault and his reflection about control and security.
Pacchetto sicurezza e fattore religioso
Pierluigi Consorti
Stato, Chiese e Pluralismo Confessionale , 2011,
Abstract: SOMMARIO: 1. Cos’è il pacchetto sicurezza - 2. Alcune considerazioni preliminari - 3. Il visto per “motivi religiosi” - 4. I Centri di identificazione ed espulsione ed i CARA -5. Il matrimonio degli stranieri.
La nuova disciplina del matrimonio degli stranieri alla luce del pacchetto sicurezza. I suoi riflessi sul matrimonio concordatario
Pierluigi Consorti
Stato, Chiese e Pluralismo Confessionale , 2011,
Abstract: SOMMARIO: 1. La capacità matrimoniale dello straniero prima del pacchetto sicurezza - 2. La novella dell’art. 116 c.c. - 3. Il diritto al matrimonio nel pacchetto sicurezza - 4. Art. 116 c.c. e matrimonio concordatario - 5. Pubblicazioni civili e matrimonio concordatario - 6. Trascrivibilità del matrimonio concordatario di cittadino straniero che non documenta la regolarità del soggiorno - 7. Matrimonio concordatario degli stranieri non cattolici - 8. Conclusione
Globalizzazione della democrazia, laicità e religioni
Pierluigi Consorti
Stato, Chiese e Pluralismo Confessionale , 2011,
Abstract: SOMMARIO: 1. Globalizzazione della democrazia e delocalizzazione delle identità - 2. Globalizzazione: valori universali e identità particolari - 3. Identità democratica v. identità democratiche - 4. Globalizzazione ed esportazione della democrazia - 5. Globalizzazione e secolarizzazione - 6. Globalizzazione e riconoscimento delle identità particolari - 7. Democrazie e religioni - 8. Legge morale, legge civile, laicità - 9. Valori v. “valori laici” e “valori religiosi” - 10. Globalizzazione della democrazia e laicità dello Stato.
Inter-religious dialogue: a secular challenge
Pierluigi Consorti
Stato, Chiese e Pluralismo Confessionale , 2011,
Abstract: Testo rivisto dell’intervento svolto a Torino il 23 maggio 2007 in occasione del Corso – organizzato dalla Fondazione “La Gregoriana” e dall’Istituto internazionale Maritain – per Diplomatici dei Paesi del Mediterraneo e del Medio Oriente su “The Catholic Church and the International Policy of the Holy See” [Rome (May 7-20, 2007) – Turin (May 21-27, 2007)], destinato alla pubblicazione negli Atti del Corso.
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