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Effect of Superoxide Dismutase on Semen Parameters and Antioxidant Enzyme Activities of Liquid Stored (5°C) Mithun (Bos frontalis) Semen
P. Perumal
Journal of Animals , 2014, DOI: 10.1155/2014/821954
Abstract: The present study was undertaken to assess the effect of superoxide dismutase (SOD) on sperm motility, and viability; total sperm abnormality; acrosomal and plasma membrane integrity; DNA abnormality; antioxidant profiles such as catalase (CAT), reduced glutathione (GSH), and total antioxidant capacity (TAC); enzymatic profiles such as aspartate amino transaminase (AST), and alanine amino transaminase (ALT); and biochemical profiles such as malondialdehyde (MDA) production and cholesterol efflux. Total numbers of 50 ejaculates were collected twice a week from eight mithun bulls and semen was split into four equal aliquots, diluted with the TEYC extender. Group 1: semen without additives (control), and group 2 to group 4: semen was diluted with 50?U/mL, 100?U/mL, and 150?U/mL of SOD, respectively. These seminal parameters, antioxidant, enzymatic, and biochemical profiles were assessed at 5°C for 1, 6, 12, 24, and 30?h of incubation. Inclusion of SOD into diluent resulted in significant ( ) decrease in percentages of dead spermatozoa, abnormal spermatozoa, and acrosomal abnormalities at different hours of storage periods as compared with control group. Additionally, SOD at 100?U/mL has significant improvement in quality of mithun semen than SOD at 50 or 150?U/mL stored in in-vitro for up to 30?h. It was concluded that the possible protective effects of SOD on sperm parameters are that it prevents MDA production and preserves the antioxidants and intracellular enzymes during preservation. 1. Introduction Mithun (Bos frontalis) is a semiwild free-range, rare bovine species present in the North-Eastern Hill (NEH) region of India. It is believed to have originated more than 8000 years ago from wild Indian gaur (Bos gaurus) [1]. The animal has an important place in the social, cultural, religious, and economic life of the tribal population particularly in the states of Arunachal Pradesh, Nagaland, Manipur, and Mizoram. Recent statistics indicates that the mithun population is decreasing gradually due to lack of suitable breeding bulls, increase in intensive inbreeding practices, declining land area for grazing, and lack of suitable breeding and feeding management in NEH region. Greater efforts are required from all quarters to preserve the mithun population to enhance the socioeconomic status of this region. Since mithuns are semiwild animals and not fully domesticated, natural breeding is practiced in this species with accompanied limitations like cost and disease transmission. Thus, use of AI for improvement of its pedigree is utmost essential. Cold storage
Experimental Study on the Roll of Waterproofing Admixtures on the Strength and Durability of Concrete
A. Geetha,P. Perumal
Journal of Engineering and Applied Sciences , 2012,
Abstract: This study deals, the durability and strength of concrete using admixtures. This addition of water proofing admixtures turns concrete into a construction material in harmony with sustainable building development. The addition of water proofing admixtures also increases the various strength of concrete. These studies were carried out by conducting tensile, compressive and flexural strength tests of the concrete specimen with and without admixtures for various dosages and various curing periods of 7 and 28 days. For flexural strength concrete prism of size 100x100x500 mm, for compression test cube of 150x150x150 mm, for split tensile test cylinders of 150x300 mm. For durability study permeability tests were conducted on the cube specimen of size 150x150x150 mm. The results showed that the presence of waterproofing admixtures always improves the corrosion resistance and thus, increases the strength of concrete.
Performance of superplasticised fibrous concrete on RCPT test under thermoshock
G. Elangovan,P. Perumal
Journal of Engineering and Applied Sciences , 2010,
Abstract: This experimental investigation is about the chloride ion penetration of concrete under effect of thermo shock on superplasticised fibrous concrete at 200 degree Celsius. As reported in previous studies concretes made with purely Ordinary Portland Cement (OPC) showed evidence of a steady decline in residual strength when subjected to thermoshock under elevated temperatures. In the present study tests were conducted to minimize the reduction of residual strength under compression, minimize the chloride ion penetration of OPC concrete by using chemical admixtures like superplasticiser and with different individual fibers. This paper exposes the details of the test programme, results and also compares against the same with earlier reports. From this test results, it was found that the residual properties of concrete were not affected and data available here will be helpful in assessing the residual strength of concrete after thermoshock.
An Efficient Preparation of 1,2-Diamino-1-phenylheptane
S. Thennarasu,P. T. Perumal
Molecules , 2002, DOI: 10.3390/70600487
Abstract: A convenient four-step method for the preparation of the lipophilic vicinal diamine 1,2-diamino-1-phenylheptane is described. Condensation involving octan-2-one, benzaldehyde and ammonia is reported. Regioselective Schmidt rearrangement of 2,6-diphenyl-3-pentyl-piperidin-4-one (1) to 2,7-diphenyl-3-pentyl hexahydrodiazapin-5-one (3) is presented. Hydrolysis of 2,7-diphenyl-3-pentyl hexahydrodiazapin-5-one to 1,2-diamino-1-phenylheptane (4) is also reported for the first time.
5-(1-Acetamido)benzyl-5-methyl Imidazolidin-2,4-dione
S. Thennarasu,P. T. Perumal
Molbank , 2003, DOI: 10.3390/m326
Abstract: No abstract available
Retargeting GCC: Do We Reinvent the Wheel Every Time?
Saravana Perumal P,Amey Karkare
Computer Science , 2013,
Abstract: Porting GCC to new architecture requires writing a Machine Description (MD) file that contains mapping from GCC's intermediate form to the target assembly code. Constructing an MD file is a difficult task because it requires the user to understand both (a) the internals of GCC, and (b) the intricacies of the target architecture. Instruction sets of different architectures exhibit significant amount of semantic similarities across a large class (for example, the instruction sets for RISC architectures) and differ only in syntax. Therefore, it is expected that MD files of machines with similar architectures should also have similarities. To confirm our hypothesis, we created "mdcompare", a tool to (a) extract RTL patterns (machine independent abstraction of RTL templates) from MD files of well known architectures and (b) compare the similarity of patterns across architectures. The results are encouraging; we found that 28% -- 70% RTL expressions are similar across pairs of MD files, the similarity percentage being on the higher side for pairs of similar architectures.
WOUND HEALING ACTIVITY OF ETHANOL EXTRACT OF PSEUDARTHRIA VISCIDA LINN
M. Vijayabaskaran,P. Sajeer,P. Perumal
International Research Journal of Pharmacy , 2011,
Abstract: The wound healing activity of topically applied ethanol extract of Pseudarthria viscida was evaluated in wistar rat by excision wound model for a period of 12 days. The extract was prepared as ointment form (5 and 10% w/w) and applied on Wistar rats. Neomycin ointment 0.5%w/w was used as standard drug. The healing of the wound was assessed by the rate of wound contraction, period of epithelialisation, skin breaking strength. Both the ointments (5% and 10% w/w) of Pseudarthria viscida extract promoted the wound-healing activity significantly when compared to the standard drug. High rate of wound contraction, decrease the period for epithelialisation, high skin breaking strength were observed in animals treated with 10% w/w extract ointment when compared to the control group of animals. So ethanol extract of Pseudarthria viscida in the form of 10% ointment promote wound-healing activity better than the former concentration, 5%. The result obtained from this study indicates that ethanol extract of Pseudarthria viscida accelerates the wound healing process by decreasing the surface area of the wound.
Adaptive Simulated Annealing-Useful Lessons Learned
A. Iyem Perumal,S.P. Rajagopalan
International Journal of Soft Computing , 2012,
Abstract: Simulated Annealing (SA) is a powerful stochastic search method applicable to a wide range of problems. It can produce very high quality solutions for hard combinatorial optimization problems. SA can be generalized to fit non-convex cost-functions arising in a variety of problems which is known as Boltzmann Annealing (BA). The purpose of describing Simulated Quenching (SQ) and Fast Annealing (FA) is to highlight the importance of Adaptive Simulated Anealing(ASA). ASA is a global optimization algorithm based on an associated proof that the parameter space can be sampled much more efficiently than by using the previous Simulated algorithm.
5-Chloro-3-[(E)-1,2-diphenylethenyl]-1H-indole
M. NizamMohideen,G. Bhaskar,P. T. Perumal
Acta Crystallographica Section E , 2010, DOI: 10.1107/s1600536810034719
Abstract: In the title compound, C22H16ClN, the pyrrole system makes a dihedral angle of 68.9 (1)° with the plane of phenyl ring at the ethenyl 1-position. An intramolecular C—H...π interaction is observed. In the crystal, intermolecular C—H...π interactions link the molecules into infinite chains running along the b axis.
1-Benzyl-3-(1,2-diphenylethenyl)-1H-indole
M. NizamMohideen,G. Bhaskar,P. T. Perumal
Acta Crystallographica Section E , 2010, DOI: 10.1107/s1600536810034707
Abstract: In the title compound, C29H23N, the planar [maximum deviation from the least squares plane = 0.056 (1) ] indole ring makes dihedral angles of 83.4 (4), 69.9 (1) and 59.9 (1)°, with the least-squares planes of three benzene rings. The molecular packing is stabilized by weak intermolecular C—H...π interactions.
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