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Search Results: 1 - 10 of 24226 matches for " Paulo Mendes "
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A arte xávega na Praia da Vieira: Histórias e imagens
Paulo Mendes
Etnográfica , 2006,
Abstract:
Leukotriene-A4-Hydrolase and Basic Aminopeptidase Activities Are Related with Collagen-Induced Arthritis in a Compartment-Dependent Manner  [PDF]
Mariana Trivilin Mendes, Paulo Flavio Silveira
Open Journal of Rheumatology and Autoimmune Diseases (OJRA) , 2013, DOI: 10.4236/ojra.2013.34040
Abstract: Objective: Previous study demonstrated the involvement of basic aminopeptidase (APB) activity in the development of collagen-induced arthritis (CIA). Two zinc dependent metalloenzymes (EC 3.4.11.6 and EC 3.3.2.6) are known to exhibit concomitantly APB and leukotriene-A4-hydrolase (LT-A4-H) activities. Influence of the interrelationship between both activities on arthritic processes, however, is presently uncertain. This study aimed to compare these activities in CIA. Methods: CIA was induced in rats and arthritis was assessed macroscopically. Ultracentrifugation was used to separate soluble (S) and solubilized membrane-bound (M) fractions from peripheral blood mononuclear cells (PBMCs) and synovial tissue (ST). Enzyme immunoassay was used to measure LT-A4-H activity, and Real Time Polymerase Chain Reaction was used for evaluating EC 3.4.11.6 and EC 3.3.2.6 gene expressions. Results: The existence of genes for EC 3.3.2.6 and EC 3.4.11.6 was demonstrated in the ST. Compared with control, LT-A4-H activity increased in synovial fluid (SF) and in S-PBMCs of CIA-arthritic and CIA-resistant and in M-ST of CIA-resistant, while it decreased in M-PBMCs of CIA-arthritic and CIA-resistant. In all these locations APB activity remained unchanged or inversely correlated with LT-A4-H activity. Conclusions: LT-A4-H and APB activities in joint-related samples are associated, for the first time, with EC 3.3.2.6 and EC 3.4.11.6 genes, exhibiting a compartment-dependent differential modulation of their specificity, efficiency and/or affinity or an inverse concurrent pattern. Changes in LT-A4-H activity have implications for development or resistance to arthritis in CIA model with a potential to be a diagnostic tool.
Plaza del Patriarca: Sao Paulo, Brasil
Paulo Mendes da Rocha
ARQ , 2007,
Abstract:
Desafios do conhecimento
Mendes Paulo Henrique A.
Educa??o & Sociedade , 2003,
Abstract:
Linguagem e Religi o - Um jogo, de racionalidade, de identidade, de fundamentos
Paulo Mendes Pinto
REVER : Revista de Estudos da Religi?o , 2002,
Abstract:
Impact of Human Behavior on Social Opportunistic Forwarding
Waldir Moreira,Paulo Mendes
Computer Science , 2014, DOI: 10.1016/j.adhoc.2014.07.001
Abstract: The current Internet design is not capable to support communications in environments characterized by very long delays and frequent network partitions. To allow devices to communicate in such environments, delay-tolerant networking solutions have been proposed by exploiting opportunistic message forwarding, with limited expectations of end-to-end connectivity and node resources. Such solutions envision non-traditional communication scenarios, such as disaster areas and development regions. Several forwarding algorithms have been investigated, aiming to offer the best trade-off between cost (number of message replicas) and rate of successful message delivery. Among such proposals, there has been an effort to employ social similarity inferred from user mobility patterns in opportunistic routing solutions to improve forwarding. However, these research effort presents two major limitations: first, it is focused on distribution of the intercontact time over the complete network structure, ignoring the impact that human behavior has on the dynamics of the network; and second, most of the proposed solutions look at challenging networking environments where networks have low density, ignoring the potential use of delay-tolerant networking to support low cost communications in networks with higher density, such as urban scenarios. This paper presents a study of the impact that human behavior has on opportunistic forwarding. Our goal is twofold: i) to show that performance in low and high density networks can be improved by taking the dynamics of the network into account; and ii) to show that the delay-tolerant networking can be used to reduce communication costs in networks with higher density by taking the behavior of the user into account.
Social-aware Forwarding in Opportunistic Wireless Networks: Content Awareness or Obliviousness?
Waldir Moreira,Paulo Mendes
Computer Science , 2014,
Abstract: With the current host-based Internet architecture, networking faces limitations in dynamic scenarios, due mostly to host mobility. The ICN paradigm mitigates such problems by releasing the need to have an end-to-end transport session established during the life time of the data transfer. Moreover, the ICN concept solves the mismatch between the Internet architecture and the way users would like to use it: currently a user needs to know the topological location of the hosts involved in the communication when he/she just wants to get the data, independently of its location. Most of the research efforts aim to come up with a stable ICN architecture in fixed networks, with few examples in ad-hoc and vehicular networks. However, the Internet is becoming more pervasive with powerful personal mobile devices that allow users to form dynamic networks in which content may be exchanged at all times and with low cost. Such pervasive wireless networks suffer with different levels of disruption given user mobility, physical obstacles, lack of cooperation, intermittent connectivity, among others. This paper discusses the combination of content knowledge (e.g., type and interested parties) and social awareness within opportunistic networking as to drive the deployment of ICN solutions in disruptive networking scenarios. With this goal in mind, we go over few examples of social-aware content-based opportunistic networking proposals that consider social awareness to allow content dissemination independently of the level of network disruption. To show how much content knowledge can improve social-based solutions, we illustrate by means of simulation some content-oblivious/oriented proposals in scenarios based on synthetic mobility patterns and real human traces.
Social-aware Opportunistic Routing: The New Trend
Waldir Moreira,Paulo Mendes
Computer Science , 2014, DOI: 10.1007/978-1-4614-3514-3_2
Abstract: Since users move around based on social relationships and interests, the resulting movement patterns can represent how nodes are socially connected (i.e., nodes with strong social ties, nodes that meet occasionally by sharing the same working environment). This means that social interactions reflect personal relationships (e.g., family, friends, co-workers, passers-by) that may be translated into statistical contact opportunities within and between social groups over time. Such contact opportunities may be exploited to ensure good data dissemination and retrieval, even in the presence of intermittent connectivity. Thus, in the last years, a new trend based on social similarity emerged where social relationships, interests, popularity and among others, are used to improve opportunistic routing. In this chapter, the reader will learn about the different approaches related to opportunistic routing focusing on the social-aware approaches and how such approaches make use of social information derived from opportunistic contacts to improve data forwarding. Additionally, a brief overview on the existing taxonomies for opportunistic routing as well as an updated one are provided along with a set of experiments in scenarios based on synthetic mobility models and human traces in order to show the potential of social-aware solutions.
Caffeine influence on the performance of the 5000m race
Marangon Antonio FC,Mendes Paulo
Journal of the International Society of Sports Nutrition , 2011, DOI: 10.1186/1550-2783-8-s1-p12
Abstract:
Centro Cultural FIESP: Sao Paulo, Brasil
Mendes da Rocha,Paulo; Pi?ón,Helio;
ARQ (Santiago) , 2008, DOI: 10.4067/S0717-69962008000100002
Abstract: the introduction of autonomous structures to the access level of this pre-existing office building not only resolves the appropriate installation of public program but also proposes a way to relate the interiors with the urban life of a dense metropolitan avenue through the articulations of its planes and levels
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