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Search Results: 1 - 10 of 325222 matches for " Patyar S "
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Lornoxicam: a Newer NSAID
Byrav PDS,Medhi B,Prakash A,,Patyar S
Indian Journal of Physical Medicine and Rehabilitation , 2009,
Abstract: Pain relieving drugs are one of the most commonly useddrugs worldwide either through prescription or as overthe counter medication. Non-steroidal anti-inflammatorydrugs usually abbreviated as NSAIDs, are the drugs withanalgesic, antipyretic and, in higher doses, with antiinflammatoryeffects. NSAIDs inhibit cyclooxygenase(COX) 1 and 2. So, most of the side effects develop as aresult of cyclooxygenase inhibitory activity. CertainNSAIDs, for example, rofecoxib and nimesulide havebeen banned because of their adverse effects.Lornoxicam (chlortenoxicam) is a strong analgesic andanti-inflammatory NSAID of the oxicam class with bettertolerability profile when compared to other NSAIDs. Itsanalgesic activity is comparable to that of opioids. It hasbeen shown to be effective in the treatment of postoperative pain and rheumatoid arthritis (RA). The presentreview provides an overview of lornoxicam.
Bacteria in cancer therapy: a novel experimental strategy
S Patyar, R Joshi, DS Prasad Byrav, A Prakash, B Medhi, BK Das
Journal of Biomedical Science , 2010, DOI: 10.1186/1423-0127-17-21
Abstract: Cancer is characterized by uncontrolled and invasive growth of cells. These cells may spread to other parts of the body, and this is called metastasis. Although conventional anticancer therapies, consisting of surgical resection, radiotherapy and chemotherapy, are effective in the management of many patients but for about half of cancer sufferers these are ineffective, so alternative techniques are being developed to target their tumours. Experimental cancer treatments are medical therapies intended or claimed to treat cancer by improving, supplementing or replacing conventional methods. These include photodynamic therapy, HAMLET (human alpha-lactalbumin made lethal to tumor cells), gene therapy, telomerase therapy, hyperthermia therapy, dichloroacetate (DCA), non-invasive RF cancer treatment, complementary and alternative therapy, diet therapy, insulin potentiating therapy and bacterial treatment [1]. But many of these therapies are controversial due to lack of evidence, efficacy, feasibility, availability, specificity and selectivity. It has been reported that some microorganisms display selective replication in tumor cells or preferential accumulation in the tumor micro-environment thus offering a great potential for cancer therapy. Many viruses, like vaccinia virus, Newcastle disease virus, reovirus and adenovirus with an E1a deletion, which are intended to achieve selective replication and killing of tumor cells have been investigated. Viruses have shown the most potential to carry altered genes to cancer cells, to find target cells in body and ability to latch onto these cells. Oncolytic viruses cause lysis (rupture) of cancer cells, which can then be processed by the adaptive immune system, which can then target similar cells in other parts of the body. But the effective use of such viruses is sometimes hindered by the production of potentially neutralizing antibodies generated against them [2]. It has been reported that some bacterial species also preferenti
Study of the Structural and Electrical Properties of Cr-Doped BiFeO3 Ceramic  [PDF]
S. S. Arafat, S. Ibrahim
Materials Sciences and Applications (MSA) , 2017, DOI: 10.4236/msa.2017.810051
Abstract: Multiferroic BiFe1-xCrxO3 (x = 0.2 and 0.4) ceramics were synthesized in a single phase. The effects of Cr3+ substitution on the crystal structure, dielectric permittivity and leakage current were investigated. Preliminary X-ray structural studies revealed that the samples had a rhombohedral perovskite crystal structure. The dielectric constant ε' significantly increased while the dielectric loss tanδ was substantially decreased with the increase in Cr3+ substitution. The temperature effect on the dielectric properties exhibited an anomaly corresponding to magneto-electric coupling in the samples and was shifted to lower temperatures with the increase in Cr3+ substitution. The leakage current density also reduced in magnitude with the increase in the Cr3+ substitution.
Degree Splitting of Root Square Mean Graphs  [PDF]
S. S. Sandhya, S. Somasundaram, S. Anusa
Applied Mathematics (AM) , 2015, DOI: 10.4236/am.2015.66086
Abstract: Let \"\" be an injective function. For a vertex labeling f, the induced edge labeling \"\" is defined by, \"\" or \"\"; then, the edge labels are distinct and are from \"\". Then f is called a root square mean labeling of G. In this paper, we prove root square mean labeling of some degree splitting graphs.
A Parameter Estimation Model of G-CSF: Mathematical Model of Cyclical Neutropenia  [PDF]
S. Balamuralitharan, S. Rajasekaran
American Journal of Computational Mathematics (AJCM) , 2012, DOI: 10.4236/ajcm.2012.21002
Abstract: We investigate the FFT (Fast Fourier Transform) model and G-CSF (granulocyte colony-stimulating factor) treatment of CN (Cyclical Neutropenia). We collect grey collies and normal dog’s data from CN and analyze the G-CSF treatment. The model develops the dynamics of circulating blood cells before and after the G-CSF treatment. This is quite natural and useful for the collection of laboratory data for investigation. The proposed interventions are practical. This reduces the quantity of G-CSF required for potential maintenance. This model gives us good result in treatment. The changes would be practical and reduce the risk side as well as the cost of treatment in G-CSF.
Synthesis, Thermal Behaviour, XRD, and Luminescent Properties of Lighter Lanthanidethiodipropionate Hydrates Containing Aminogunidine as Neutral Ligand  [PDF]
S. Packiaraj, S. Govindarajan
Open Journal of Inorganic Chemistry (OJIC) , 2014, DOI: 10.4236/ojic.2014.43006
Aminoguanidine lanthanide thiodipropionate hydrates of composition [Ln(Agun)2(tdp)3·nH2O], Agun = Aminoguanidine, tdp = thiodipropionic acid, where Ln = La, Pr, Nd and Sm if n = 2, have been prepared and characterized by physic-chemical techniques.
Fuzzy Based Intelligent Monitoring of Critical Lines in the Restructured Power Market  [PDF]
S. Rajasekaran, S. Sathiyamoorthy
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.79191
Abstract: Restructured electric market environment allows the power wheeling transactions between the power producers and customers to meet the growing load demand. This will lead to the possible of congestion in the transmission lines. The possible contingencies of power components further worsen the scenario. This paper describes the methodology for the identification of critical transmission line by computing the real power and reactive power performance indices. It also demonstrates the importance of fuzzy logic technique used to rank the transmission lines according to the severity and demonstrated on IEEE-30 bus system.
Error Correction Circuit for Single-Event Hardening of Delay Locked Loops  [PDF]
S. Balaji, S. Ramasamy
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.79210
Abstract: In scaled CMOS processes, the single-event effects generate missing output pulses in Delay-Locked Loop (DLL). Due to its effective sequence detection of the missing pulses in the proposed Error Correction Circuit (ECC) and its portability to be applied to any DLL type, the ECC mitigates the impact of single-event effects and completes its operation with less design complexity without any concern about losing the information. The ECC has been implemented in 180 nm CMOS process and measured the accuracy of mitigation on simulations at LETs up to 100 MeV-cm2/mg. The robustness and portability of the mitigation technique are validated through the results obtained by implementing proposed ECC in XilinxArtix 7 FPGA.
High Frequency Charging Techniques—Grid Connected Power Generation Using Switched Reluctance Generator  [PDF]
S. Sridharan, S. Sudha
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.714352
Abstract: Power generation becomes the need of developed, developing and under developed countries to meet their increasing power requirements. When affordability increases their requirement of power increases, this happens when increased per capita consumption. The existing power scenario states that highest power is produced using firing of coals called thermal energy. A high efficiency Switched Reluctance Generator (SRG) based high frequency switching scheme to enhance the output for grid connectivity is designed, fabricated and evaluated. This proposed method generates the output for the low wind speed. It provides output at low speed because of multi-level DC-DC converter and storage system. It is an efficient solution for low wind power generation. The real time readings and results are discussed.
Calculation of the Gravitational Constant G Using Electromagnetic Parameters  [PDF]
Jesús Sánchez
Journal of High Energy Physics, Gravitation and Cosmology (JHEPGC) , 2017, DOI: 10.4236/jhepgc.2017.31012
Abstract: In this paper, we will derive the following formula for the value of the gravitational constant G: \"\" (1). This equation has only 0.81% error compared to the common accepted value \"\" [1]. The parameters in the equation are the following: \"\" the fine structure constant, q the elementary charge, \"\" the mass of the electron, \"\" the permittivity of the free space, e the exponential function and \"\" the relation between a circumference and its diameter. Values attached: \"\" [2], \"\"</span
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