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Search Results: 1 - 10 of 306140 matches for " Patricia J. Boda "
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Medications in Mexico: The Growth and Distribution of Pharmacies in Ciudad Juárez, Chihuahua, Mexico from 1996-2011  [PDF]
Patricia J. Boda
International Journal of Geosciences (IJG) , 2013, DOI: 10.4236/ijg.2013.46A2008
Abstract:

US pharmacies tend to be located at intersections of major cross streets throughout a city, while in the case of Mexican border cities pharmacies are clustered close to US-Mexico border crossings. Presumably this is due to the volume of US clients who frequent the pharmacies. Although the precise number of border crossings to purchase medications is unclear, it is thought to be significant. In the past, patient-based surveys were the primary source for information regarding US residents crossing the border into Mexico for prescription medications. The current study examines the distribution of pharmacies throughout Ciudad Juárez, Chihuahua, Mexico, recording the change in the number of pharmacies over a 15-year period and suggesting the scale of US residents who use Mexican pharmacies. Field research was conducted in 1996 and 2011. Maps showing the location of pharmacies for these two years indicate a clustering of pharmacies within one and one-half miles of the city’s two principal border-crossings between the United States and Mexico. Provider-based surveys revealed that the majority of patients who use pharmacies closest to the border were US residents.

The challenge of combatting non-communicable diseases in Trinidad: Access to hospital care  [PDF]
Patricia J. Boda
Health (Health) , 2013, DOI: 10.4236/health.2013.511A2003
Abstract: Chronic illnesses, or non-communicable diseases (NCDs), account for a growing number of deaths worldwide. The English-speaking Caribbean has the highest per capita burden of NCDs in the region of the Americas [1]. This paper presents an overview of hospital availability on the island of Trinidad in the West Indies and examines rates of NCDs as reported in hospital discharge summaries. The project integrates a Geographic Information System (GIS) with epidemiologic and bio-statistical data to provide essential spatial analysis not otherwise possible. It examines the island’s ability to effectively deliver treatment to residents with NCDs by providing a geographic perspective to public data published on the internet by the Trinidad-Tobago Ministry of Health and the Central Statistical Office. The study reveals a significant variability in several dimensions of access to health care.
Root Canals and Crowns: An Analysis of the Spatial Distribution of Dental Offices in Ciudad Juárez, Chihuahua, Mexico, 1996-2011  [PDF]
Patricia J. Boda, James Harris
International Journal of Geosciences (IJG) , 2013, DOI: 10.4236/ijg.2013.46A2005
Abstract:

Every city above a certain size has health services that are located, to a large extent, close to their patients. This study analyzes the spatial distribution of dental office and the change in the number of dental offices in Ciudad Juárez, Chihuahua, Mexico over a 15-year time period. Research was conducted in 1996 and 2011. Maps showing the location of dental offices for these two years indicate a clustering of dental offices within one and one-half miles of the city’s two principal border-crossing points between the United States and Mexico. Provider-based surveys were also used to determine the mix of patients (US or Mexican citizens) at the dental offices found throughout the city. By 2011, nearly all of the dental offices clustered within one and one-half miles of the two principal US-Mexico border crossings had 100% of their patients from the United States.

Availability and accessibility of diabetes clinics on Trinidad: An analysis using proximity tools in a GIS environment  [PDF]
Patricia Boda
Health (Health) , 2013, DOI: 10.4236/health.2013.511A2006
Abstract:

Non-communicable diseases (NCDs), account for a growing number of deaths worldwide. The English-speaking Caribbean has the highest per capita burden of NCDs in the region of the Americas [1]. This paper presents an overview of availability and accessibility based on clinic hours and physician fulltime equivalents (FTE) on the island of Trinidad devoted to diabetes and wound care. The project integrates a Geographic Information System (GIS) with epidemiologic and bio-statistical data to provide a necessary spatial analysis not otherwise possible. It examines the island’s ability to effectively deliver treatment to residents with diabetes by providing a geographic perspective to data published on the internet by the Trinidad-Tobago Ministry of Health and the Central Statistical Office. Results indicate a significant regional variability in both numbers of physicians and office hours devoted to diabetes treatment.

Investigation to improve the method of assessing the breeding value of beef cattle
I Boda, J Dohy
Genetics Selection Evolution , 1980, DOI: 10.1186/1297-9686-12-1-127b
Abstract:
Investigation to improve the method of assessing the breeding value of beef cattle
Boda I,Dohy J
Genetics Selection Evolution , 1980,
Abstract:
Theoretical Studies of Dynamic Interactions in Excited States of Hydrogen-Bonded Systems
Marek J. Wójcik,Marek Boczar, ukasz Boda
Journal of Atomic, Molecular, and Optical Physics , 2012, DOI: 10.1155/2012/985490
Abstract: Theoretical model for vibrational interactions in the hydrogen-bonded benzoic acid dimer is presented. The model takes into account anharmonic-type couplings between the high-frequency O–H and the low-frequency O⋯O stretching vibrations in two hydrogen bonds, resonance interactions between two hydrogen bonds in the dimer, and Fermi resonance between the O–H stretching fundamental and the first overtone of the O–H in-plane bending vibrations. The model is used for theoretical simulation of the O–H stretching IR absorption bands of benzoic acid dimers in the gas phase in the first excited singlet state. Ab initio CIS and CIS(D)/CIS/6-311
Energetics of ion competition in the DEKA selectivity filter of neuronal sodium channels
D. Boda,G. Leaf,J. Fonseca,B. Eisenberg
Physics , 2015, DOI: 10.5488/CMP.18.13601
Abstract: The energetics of ionic selectivity in the neuronal sodium channels is studied. A simple model constructed for the selectivity filter of the channel is used. The selectivity filter of this channel type contains aspartate (D), glutamate (E), lysine (K), and alanine (A) residues (the DEKA locus). We use Grand Canonical Monte Carlo simulations to compute equilibrium binding selectivity in the selectivity filter and to obtain various terms of the excess chemical potential from a particle insertion procedure based on Widom's method. We show that K$^{+}$ ions in competition with Na$^{+}$ are efficiently excluded from the selectivity filter due to entropic hard sphere exclusion. The dielectric constant of protein has no effect on this selectivity. Ca$^{2+}$ ions, on the other hand, are excluded from the filter due to a free energetic penalty which is enhanced by the low dielectric constant of protein.
ACTA MATHEMATICA UNIVERSITATIS COMENIANAE
E. Boda and R. Farnbauer
ACTA MATHEMATICA UNIVERSITATIS COMENIANAE , 2003,
Abstract: . Let $I=(X^{a}-Y^{b},X^{c}-Y^{d})\cdot k[X,Y]$ be an ideal of dimension zero in polynomial ring in two variables. In this note a formula for standard basis of $I$ with respect of anti-graded lexicographic order is derived. As a consequence the discussion on the common points of the plane curves $V(X^{a}-Y^{b})$ and $V(X^{c}-Y^{d})$ is given.
Partial protection against collagen antibody-induced arthritis in PARP-1 deficient mice
Samuel García, Ana Boda?o, Antonio González, Jerónimo Forteza, Juan J Gómez-Reino, Carmen Conde
Arthritis Research & Therapy , 2005, DOI: 10.1186/ar1865
Abstract: Rheumatoid arthritis (RA) is characterized by inflammation, synovial hyperplasia, pannus formation and progressive destruction of cartilage and bone [1,2]. In RA, inflammatory cytokines, chemokines, growth factors and adhesion molecules are produced by leukocytes and resident synoviocytes. These factors perpetuate chronic inflammation by the recruitment of additional inflammatory cells into the sublining region that, in turn, lead to continuous production of inflammatory mediators and enzymes, resulting in destruction of joint structures [3-8]. The efficacy of treatments with tumor necrosis factor (TNF) and IL-1 inhibitors strongly support the key role of inflammatory cytokines in the pathogenesis of RA [9,10] and points to therapeutic approaches directed toward regulation of cytokine networks involved in RA.Poly(ADP-ribose) polymerase (PARP)-1 is a highly conserved nuclear zinc-finger protein involved in maintenance of genomic integrity. PARP-1 detects DNA breakage generated by several genotoxic agents and synthesizes and transfers ADP ribose units (poly(ADPribosyl)ation activity) into acceptor proteins involved in the conservation of chromatin structure and DNA metabolism, modulating in this way DNA repair and cell survival [11,12]. Studies with PARP-1 deficient mice or with chemical inhibitors have enlarged the physiological role of this protein. In these situations, lack of PARP-1 function protects against several disorders with an inflammatory component, such as endotoxic shock [13], streptozotocin induced diabetes [14], chronic colitis [15] and uveitis [16]. Two mechanisms have been proposed to explain the role of PARP-1 in these diseases. One mechanism is related to massive PARP-1 activation induced by genotoxic injury developed during the inflammatory process. In this case, hyperactivated PARP-1 would lead to ATP depletion and cell dysfunction [17]. The other proposed mechanism is related to a functional link between PARP-1 and inflammation-related transcrip
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