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Search Results: 1 - 10 of 36787 matches for " Patrícia Medeiros-Souza "
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The Use of Herbal Medicine in Alzheimer's Disease—A Systematic Review
Leopoldo Luiz dos Santos-Neto,Maria Alice de Vilhena Toledo,Patrícia Medeiros-Souza,Gustavo Almeida de Souza
Evidence-Based Complementary and Alternative Medicine , 2006, DOI: 10.1093/ecam/nel071
Abstract: The treatments of choice in Alzheimer's disease (AD) are cholinesterase inhibitors and NMDA-receptor antagonists, although doubts remain about the therapeutic effectiveness of these drugs. Herbal medicine products have been used in the treatment of Behavioral and Psychological Symptoms of Dementia (BPSD) but with various responses. The objective of this article was to review evidences from controlled studies in order to determine whether herbs can be useful in the treatment of cognitive disorders in the elderly. Randomized controlled studies assessing AD in individuals older than 65 years were identified through searches of MEDLINE, LILACS, Cochrane Library, dissertation Abstract (USA), ADEAR (Alzheimer's Disease Clinical Trials Database), National Research Register, Current Controlled trials, Centerwatch Trials Database and PsychINFO Journal Articles. The search combined the terms Alzheimer disease, dementia, cognition disorders, Herbal, Phytotherapy. The crossover results were evaluated by the Jadad's measurement scale. The systematic review identified two herbs and herbal formulations with therapeutic effects for the treatment of AD: Melissa officinalis, Salvia officinalis and Yi-Gan San and BDW (Ba Wei Di Huang Wan). Ginkgo biloba was identified in a meta-analysis study. All five herbs are useful for cognitive impairment of AD. M. officinalis and Yi-Gan San are also useful in agitation, for they have sedative effects. These herbs and formulations have demonstrated good therapeutic effectiveness but these results need to be compared with those of traditional drugs. Further large multicenter studies should be conducted in order to test the cost-effectiveness of these herbs for AD and the impact in the control of cognitive deterioration.
Diagnosis and control of polypharmacy in the elderly
Medeiros-Souza,Patrícia; Santos-Neto,Leopoldo Luiz dos; Kusano,Liana Tieko Evangelista; Pereira,Maurício Gomes;
Revista de Saúde Pública , 2007, DOI: 10.1590/S0034-89102006005000050
Abstract: the article had the purpose of commenting on studies on polypharmacy in the elderly, focusing on diagnosis and control. polypharmacy is defined as the use of a number of medications at the same time and the use of additional drugs to correct drug adverse effects. the fact that the elderly take more medications for the treatment of several diseases makes them more susceptible to the occurrence of adverse reactions. prophylactic actions such as balanced prescriptions are vital to reduce the incidence of these reactions and prevent longer hospital stay, increased costs and aggravation of the elderly health condition.
Use of psychotropic medications by caregivers of elderly patients with dementia: is this a sign of caregiver burden?
Camargos, Einstein Francisco;Souza, Andrea Brígida;Nascimento, Aline Silva;Morais-e-Silva, Alessandra Cicari;Quintas, Juliana Lima;Louzada, Luciana Lilian;Medeiros-Souza, Patricia;
Arquivos de Neuro-Psiquiatria , 2012, DOI: 10.1590/S0004-282X2012000300003
Abstract: this study evaluated the consumption of psychotropic medications by caregivers of elderly patients with or without dementia. this was a cross-sectional study conducted at all geriatric units in brasília, brazil, during a two-month period. structured interviews were performed with 311 caregivers of people with or without dementia and they completed questionnaires. among the caregivers, 196 (63%) were caregivers of patients with dementia and 115 (37%) were caregivers of patients without dementia. forty-four caregivers (14.1%) were taking psychotropic drugs (benzodiazepines or antidepressants), and this usage was more frequent among caregivers of patients with dementia (p<0.01). twenty-two caregivers of patients with dementia (11.4%) had used sleeping pills after beginning care, compared with only five (4.3%) caregivers of patients without dementia (p<0.01). in conclusion, this study found that caregivers of patients with dementia took psychotropic drugs (benzodiazepines and antidepressants) more frequently than the ones of patients without dementia.
Trazodone for the treatment of sleep disorders in dementia: an open-label, observational and review study
Camargos, Einstein Francisco;Pandolfi, Marcela Basso;Freitas, Marco Polo Dias;Quintas, Juliana Lima;Lima, Juliana de Oliveira;Miranda, Leandra Camapum;Pimentel, Luciano Wanderley;Medeiros-Souza, Patricia;
Arquivos de Neuro-Psiquiatria , 2011, DOI: 10.1590/S0004-282X2011000100010
Abstract: sleep disorders (sd) in patients with dementia are very common in clinical practice. the use of antidepressants with hypnotic actions, such as trazodone, plays an important role in these cases. the aim of this study is to present a profile of the use of trazodone in demented patients with sd, as well as a review of trazodone hydrochloride in sd. we evaluated 178 elderly patients with alzheimer's disease and other dementias, clinically presenting sd and treated with hypnosedative medications. in the one-year period comprising the study, 68 (38.2%) of the 178 had sleep disorders. most patients (114; 64%) had a diagnosis of alzheimer's disease. approximately 85% of patients with sd used hypnosedative drugs. trazodone was the most commonly used drug among patients (n = 35), with an effectiveness of 65.7%. trazodone has been shown to be a good option for treatment of the elderly with dementia and associated sd.
Testes empíricos sobre o comportamento assimétrico dos custos nas empresas brasileiras
Medeiros, Otávio Ribeiro de;Costa, Patrícia de Souza;Silva, César Augusto Tibúrcio;
Revista Contabilidade & Finan?as , 2005, DOI: 10.1590/S1519-70772005000200005
Abstract: the study tests and confirms the hypothesis that costs of brazilian firms are sticky, i.e. that costs increase with more intensity when revenues increase than in the opposite direction, as shown by recent empirical evidence involving american firms. as opposed to this evidence, however, the sticky behavior does not seem to decrease when periods over one year are considered. the possibility of a partial reversion of the asymmetry when lagged periods are tested is confirmed in the study. the adopted methodology involves different types of panel data regressions. the paper intends to contribute to a better understanding of brazilian firms' cost behavior related to changes in the firms' activity level, which is a relevant theme for business administration, accountants and external financial analysts. by using a sample of 198 firms within a 17-year period, it was found that the properties of the sticky costs model proposed by anderson, banker e janakiraman (2003) are partially applicable to brazil.
Antioxidant intake among Brazilian adults - The Brazilian Osteoporosis Study (BRAZOS): a cross-sectional study
Marcelo Medeiros Pinheiro, Rozana Ciconelli, Gabriela Chaves, Luana Aquino, Claudia Juzwiak, Patrícia de Souza Genaro, Marcos Ferraz
Nutrition Journal , 2011, DOI: 10.1186/1475-2891-10-39
Abstract: The sample comprised 2344 individuals aged 40 years or older from 150 cities and was based on a probabilistic sample from official data. The research was conducted through in-home interviews administered by a team trained for this purpose. Dietary intake information was obtained through 24-h recall. The Nutrition Data System for Research software program was used to analyze data on the intake of vitamins A, C and E, selenium and zinc, which was compared to Dietary Reference Intakes (DRIs). Differences in intake according to sex, anthropometrics, socioeconomic status and region were also evaluated. The SPSS statistical package (version 13) was used for the statistical analysis. P-values < 0.05 were considered significant.Higher proportions of low intake in relation to recommended values were found for vitamin E (99.7%), vitamin A (92.4%) and vitamin C (85.1%) in both genders. Intake variations were found between different regions, which may reflect cultural habits.These results should lead to the development of public health policies that encourage educational strategies for improving the intake of micronutrients, which are essential to overall health and prevention of non-communicable diseases.In the last 50 years, Brazil has gone through changes in eating habits, with a greater intake of processed foods, meat, oil and vegetable fat as well as a low consumption of fruit, vegetables and cereals [1-3]. These aspects, together with a sedentary lifestyle, have contributed toward a greater prevalence of obesity and other non-communicable chronic diseases [4] as well as higher disability and mortality rates [5], especially those related to cardiovascular disease [4-6].Previous national data demonstrate that only 2 to 3% of total food intake corresponds to fruit, legumes and vegetables [2], which are important sources of nutrients with antioxidant functions. These percentages correspond to approximately one third of the internationally recommended intake for the prevention
A Brazilian Bacillus thuringiensis strain highly active to sugarcane borer Diatraea saccharalis (Lepidoptera: Crambidae)
Gitahy, Patrícia de Medeiros;Souza, Marlene Teixeira de;Monnerat, Rose Gomes;Arrigoni, Enrico de Beni;Baldani, José Ivo;
Brazilian Journal of Microbiology , 2007, DOI: 10.1590/S1517-83822007000300028
Abstract: the control of the major sugarcane pest, diatraea saccharalis, is limited by the stem location of the caterpillar. as part of a long-term project towards the development of an alternative and efficient delivery system of cry proteins to control the sugarcane borer, the current work describes the selection and characterization of a brazilian b. thuringiensis strain with prominent activity towards d. saccharalis. strain s76 was eleven-fold more active than the hd-1 lepidoptera-standard strain, as estimated by the lc50 of 13.06 μg/l and 143.88 μg/l, respectively. we observed bipiramidal and cuboidal crystals similar to those found in other b. thuringiensis strains with entomopathogenic activity against lepidoptera and diptera. in addition, smaller and spherical crystalline inclusions were also observed. the plasmid profile of strain s76 is similar to that of hd-1. pcr amplifications of s76 dna using cry specific primers confirmed the presence of cry1aa,cry1ab,cry1ac,cry2aa1, and cry2ab2, but not cry1ad, cry2ac and cry9 type genes. no differences that could explain the superior activity of s76 when compared to hd-1, the lepidoptera standard strain, were observed. nevertheless, its higher entomopathogenic activity has pointed this strain s76 as a potential source of cry genes to control sugarcane borer, an important pest that affects sugarcane, a crop that occupies a planted area of about 6 million ha in brazil.
Flebótomos de áreas com ocorrências de casos humanos de leishmaniose tegumentar americana no Município de Seropédica, Estado do Rio de Janeiro
Cardoso, Patrícia Giupponi;Souza, Marcos Barbosa de;Sanavria, Argemiro;Meira, Antonio de Medeiros;Meródio, Jairo Caetano;
Revista da Sociedade Brasileira de Medicina Tropical , 2009, DOI: 10.1590/S0037-86822009000200010
Abstract: american cutaneous leishmaniasis is caused by protozoa of the genus leishmania, which affects the skin and mucosa. it is primarily a zoonotic infection. sandfly surveys were conducted in four areas with occurrences of human cases of american cutaneous leishmaniasis in the municipality of seropédica. a manual method was used to catch specimens between 6:00 pm and 10:00 pm, for 12 consecutive months. from october 2004 to september 2005, we caught 2,390 individuals belonging to four species: lutzomyia intermedia accounted for 97.1% of the total collected, followed by lutzomyia whitmani (1.6%), lutzomyia migonei (1.2%) and lutzomyia oswaldoi (0.1%). the val?o das lou?as had the highest density of sandflies, followed by the localities of km 39, km 40 and ca?ador. the low diversity of species is due to significant changes in the ecotope of the region. it is suggested that american cutaneous leishmaniasis is being transmitted by lutzomyia intermedia in the municipality of seropédica.
Abordagem cirúrgica da constri o maxilar unilateral
Patrícia Medeiros Berto
Revista Dental Press de Ortodontia e Ortopedia Facial , 2009, DOI: 10.1590/s1415-54192009000500003
Application of an Educational Resource for Parents of Seven-Year-Old Children Diagnosed with Developmental Coordination Disorder  [PDF]
Patrícia Carla de Souza Della Barba
Advances in Physical Education (APE) , 2015, DOI: 10.4236/ape.2015.51001
Abstract: The present study aims to discuss the application of educational resource “Children with Developmental Coordination Disorder: at Home, at School and in the Community” (Missiuna, Rivard, & Pollock, 2011) for parents of seven-year-old children of a public school in a Brazilian city. The booklet aims to help parents and teachers identify and manage school-aged children with developmental coordination disorder (DCD). Methods: The contents of the booklet were used in a group of four parents of children previously identified with DCD in the school environment using a workshop. Results: The meetings of the parents were oriented to the characterization of the disorder. The activities helped parents understand the difficulties of their children. Conclusion: In this study it was found that the use of the educational resources together with games proved to be an important approach to working with parents of children with DCD. However, it is important to expand the number of participants in future studies.
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