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Search Results: 1 - 10 of 3271 matches for " Pascal Leroux "
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Modeling the organisation of the tutoring activity in order to assist the description of educational scenarios
Patricia Gounon,Pascal Leroux
STICEF , 2009,
Abstract: The research presented in this paper focuses on the design of tutoring activity in the context of distance learning environments. Our problematic concerns the assistance for describing the tutoring activity. We aim to specify roles and tutor involvement and also to describe the tools supporting this activity. Using tutoring activity research studies in distance learning environments, we propose a model of tutoring organisation, called Triton. We describe the methodology for using Triton. We propose to extend two EMLs (IMS-LD and LDL) based on Triton. These two cases of study show the interest to enrich the tutoring scenario of the EMLS
Technologies and distance education
Richard HOTTE,Pascal LEROUX
STICEF , 2003,
Abstract: n this paper, our aims is to clarify the university contexts and underlying instructional approaches in which on-line education works are engaged and the influence of these contexts on this same works. This positioning should facilitate the reading, interpretation and understanding of the articles of this special issue, as well as ensure the intelligibility of the current trends on the distance education. We want to make sure that the contributions to this issue are within the reach of both French-speaking academic cultures, France and Quebec. We have the feeling that there are significant differences between French and Quebecer experiences concerning the distance education and the use of ICT in education.
Proposition d’un modèle de tutorat pour la conception de dispositifs d’accompagnement en formation en ligne
Patricia Gounon,Pascal Leroux,Xavier Dubourg
Revue Internationale des Technologies en Pédagogie Universitaire , 2004,
Abstract: [Fran ais] Nous avons constaté dans la littérature le manque de prise en compte de l’accompagnement des apprenants dans la conception des dispositifs de formation en ligne. Ce manque nous semble très préjudiciable dans le cycle de vie d’une formation. C’est pourquoi, après avoir identifié les besoins d’accompagnement des apprenants dans une formation en ligne, nous proposons un modèle descriptif d’une activité de tutorat. Ce modèle sert de fondement pour guider la définition des spécifications du dispositif d’accompagnement des apprenants en matière de taches et d’outils supports de leurs activités. Dans la dernière partie de l’article, nous présentons la méthodologie d’application de ce modèle au cours du cycle de vie d’une formation. [English] The learners’ tutoring component in Web-based distance education is often neglected during the instructional design process. This omission is prejudicial in the life-cycle courseware. This is why we propose a descriptive tutoring model, after identifying learners support needs in a distance learning environment. This model is used as the foundation to guide specification definition of learner accompaniment environment in terms of tasks and tools supporting their activities. In the last part of this article, we present the application methodology using this model during the life-cycle courseware.
Modélisation d'une situation d'apprentissage en termes de connaissances et de règles pour rendre compte de l'activité de l'élève – étude dans le contexte de l'apprentissage de la lecture en classe Towards modeling pedagogical situations in terms of knowledge and rules, in order to report the learner's activity – A study of reading apprenticeship in classroom settings
Catherine Cléder,Pascal Leroux,élise Gendron,Véronique Quanquin
ALSIC : Apprentissage des Langues et Systèmes d'Information et de Communication , 2011, DOI: 10.4000/alsic.2004
Abstract: Dans cet article, nous constatons qu'une activité ne peut pas être définie uniquement par sa forme effective et les connaissances du domaine visé qui sont mises en jeu. Nous proposons de définir une activité par les connaissances du domaine d'apprentissage mises en jeu, par sa forme mais également en ce qu'elle peut influer l'état de connaissance de l'apprenant et les moyens que l'on a de vérifier cet impact.Nous proposons ici nos résultats de recherche pluridisciplinaires menés autour de la spécification et la modélisation d'activités pédagogiques dans le domaine de la lecture dans le but de construire un environnement de suivi de l'apprenant. Nous présentons la méthodologie de travail pratiquée dans l'équipe, la structure des spécifications d'activités, les modèles computationnels déduits et finalement leur mise en uvre dans un environnement de suivi de l'apprenant. In this article, we note that an activity cannot be only defined by its effective form as well as the targeted subject's learning processes engaged in performing the task. An activity is hereby described as the knowledge of the subject to be learned, in the means of its structure as well as how it can impact student's state of knowledge, and how this influence can be regulated.Results of interdisciplinary research, concerning the specification and modeling of teaching activities for the apprenticeship of reading, are presented here. The results aim at giving more insights on the subject, in order to build an adaptive learning environment that keeps track of student's learning achievements and process. This article is structured in several parts: presentation of the team's research methodology, structure of activity requirements, computational models deduced, and finally their implementation in an adaptive learning environment.
Broad Clade 2 Cross-Reactive Immunity Induced by an Adjuvanted Clade 1 rH5N1 Pandemic Influenza Vaccine
Isabel Leroux-Roels, Roger Bernhard, Pascal Gérard, Mamadou Dramé, Emmanuel Hanon, Geert Leroux-Roels
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0001665
Abstract: Background The availability of H5N1 vaccines that can elicit a broad cross-protective immunity against different currently circulating clade 2 H5N1 viruses is a pre-requisite for the development of a successful pre-pandemic vaccination strategy. In this regard, it has recently been shown that adjuvantation of a recombinant clade 1 H5N1 inactivated split-virion vaccine with an oil-in-water emulsion-based adjuvant system also promoted cross-immunity against a recent clade 2 H5N1 isolate (A/Indonesia/5/2005, subclade 2.1). Here we further analyse the cross-protective potential of the vaccine against two other recent clade 2 isolates (A/turkey/Turkey/1/2005 and A/Anhui/1/2005 which are, as defined by WHO, representatives of subclades 2.2 and 2.3 respectively). Methods and Findings Two doses of the recombinant A/Vietnam/1194/2004 (H5N1, clade 1) vaccine were administered 21 days apart to volunteers aged 18–60 years. We studied the cross-clade immunogenicity of the lowest antigen dose (3.8 μg haemagglutinin) given with (N = 20) or without adjuvant (N = 20). Immune responses were assessed at 21 days following the first and second vaccine doses and at 6 months following first vaccination. Vaccination with two doses of 3.8 μg of the adjuvanted vaccine induced four-fold neutralising seroconversion rates in 85% of subjects against A/turkey/Turkey/1/2005 (subclade 2.2) and 75% of subjects against A/Anhui/1/2005 (subclade 2.3) recombinant strains. There was no response induced against these strains in the non-adjuvanted group. At 6 months following vaccination, 70% and 60% of subjects retained neutralising antibodies against the recombinant subclade 2.2 and 2.3 strains, respectively and 40% of subjects retained antibodies against the recombinant subclade 2.1 A/Indonesia/5/2005 strain. Conclusions In addition to antigen dose-sparing, adjuvantation of inactivated split H5N1 vaccine promotes broad and persistent cross-clade immunity which is a pre-requisite for a pre-pandemic vaccine. Trial Registration ClinicalTrials.gov NCT00309634
Low-Latency Software Polar Decoders
Pascal Giard,Gabi Sarkis,Camille Leroux,Claude Thibeault,Warren J. Gross
Computer Science , 2015,
Abstract: Polar codes are a new class of capacity-achieving error-correcting codes with low encoding and decoding complexity. Their low-complexity decoding algorithms render them attractive for use in software-defined radio applications where computational resources are limited. In this work, we present low-latency software polar decoders that exploit modern processor capabilities. We show how adapting the algorithm at various levels can lead to significant improvements in latency and throughput, yielding polar decoders that are suitable for high-performance software-defined radio applications on modern desktop processors and embedded-platform processors. These proposed decoders have an order of magnitude lower latency compared to state of the art decoders, while maintaining comparable throughput. In addition, we present strategies and results for implementing polar decoders on graphical processing units. Finally, we show that the energy efficiency of the proposed decoders, running on desktop a processor, is comparable to state of the art software polar decoders.
Pro-Aging Effects of Glucose Signaling through a G Protein-Coupled Glucose Receptor in Fission Yeast
Antoine E. Roux,Alexandre Leroux,Manal A. Alaamery,Charles S. Hoffman,Pascal Chartrand ,Gerardo Ferbeyre ,Luis A. Rokeach
PLOS Genetics , 2009, DOI: 10.1371/journal.pgen.1000408
Abstract: Glucose is the preferred carbon and energy source in prokaryotes, unicellular eukaryotes, and metazoans. However, excess of glucose has been associated with several diseases, including diabetes and the less understood process of aging. On the contrary, limiting glucose (i.e., calorie restriction) slows aging and age-related diseases in most species. Understanding the mechanism by which glucose limits life span is therefore important for any attempt to control aging and age-related diseases. Here, we use the yeast Schizosaccharomyces pombe as a model to study the regulation of chronological life span by glucose. Growth of S. pombe at a reduced concentration of glucose increased life span and oxidative stress resistance as reported before for many other organisms. Surprisingly, loss of the Git3 glucose receptor, a G protein-coupled receptor, also increased life span in conditions where glucose consumption was not affected. These results suggest a role for glucose-signaling pathways in life span regulation. In agreement, constitutive activation of the Gα subunit acting downstream of Git3 accelerated aging in S. pombe and inhibited the effects of calorie restriction. A similar pro-aging effect of glucose was documented in mutants of hexokinase, which cannot metabolize glucose and, therefore, are exposed to constitutive glucose signaling. The pro-aging effect of glucose signaling on life span correlated with an increase in reactive oxygen species and a decrease in oxidative stress resistance and respiration rate. Likewise, the anti-aging effect of both calorie restriction and the Δgit3 mutation was accompanied by increased respiration and lower reactive oxygen species production. Altogether, our data suggest an important role for glucose signaling through the Git3/PKA pathway to regulate S. pombe life span.
Free dendriform algebras. Part I. A parenthesis setting
Philippe Leroux
International Journal of Mathematics and Mathematical Sciences , 2006, DOI: 10.1155/ijmms/2006/34684
Abstract: We propose both a reformulation of some known results on the free dendriform algebra on one generator from a parenthesis setting instead of using permutations and some developments as well. Moreover, by introducing the concept of NCP-operad, we show how to use the free dendriform algebra on one generator to reformulate some results obtained by Speicher in free probability.
An algebraic framework of weighted directed graphs
Philippe Leroux
International Journal of Mathematics and Mathematical Sciences , 2003, DOI: 10.1155/s0161171203302170
Abstract: We show that an algebraic formulation of weighted directed graphs leads to introducing a k-vector space equipped with two coproducts Δ and Δ˜ verifying the so-called coassociativity breaking equation (Δ˜⊗id)Δ=(id⊗Δ)Δ˜. Such a space is called an L-coalgebra. Explicit examples of such spaces are constructed and links between graph theory and coassociative coalgebras are given.
Coassociative grammar, periodic orbits, and quantum random walk over
Philippe Leroux
International Journal of Mathematics and Mathematical Sciences , 2005, DOI: 10.1155/ijmms.2005.3979
Abstract: Inspired by a work of Joni and Rota, we show that the combinatorics generated by a quantisation of the Bernoulli random walk over ℤ can be described from a coassociative coalgebra. Relationships between this coalgebra and the set of periodic orbits of the classical chaotic system x↦2x mod⁡1, x∈[0,1], are also given.
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