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Morphometric analysis of the cervical spine of Indian population by using computerized tomography
Partha Sarathi Banerjee,Amit Roychoudhury,Santanu Kumar Karmakar
Journal of Medical and Allied Sciences , 2012,
Abstract: The purpose of the present study was to measure the surgically important morphological parameters of cervical spine region of a representative sample of Indian population from the images obtained through computerized tomography (CT). Another purpose has been to compare the computed statistical mean, standard deviation and range of variation of these data with those of other Asian population and also European/American populations. With that aim, ninety five (95) CT scan data of Indian people (73 for male patients and 22 for female patients) pertaining to undeformed normal cervical spine has been collected from an Indian hospital. From these, 15 important morphological parameters have been measured. These values have been tabulated and their mean, standard deviation and range of variation have been computed. It has been found that pedicle dimensions of Indian people are smaller at almost all vertebra levels as compared to Caucasian people. Pedicle axis length for Indian people are found to be smaller at C3, C4 and C5 levels than those for other Asian people including Chinese people, but it is bigger at C6 and C7 levels. Indian people have longer measurements of pedicle length + lateral mass on an average than their other Asian counterparts at C5, C6 and C7 levels, but shorter measurements at C3 and C4 levels. The results of the present work may help in better understanding of morphological parameters of cervical spine region of Indian population. It may be further useful in designing spinal implants which would be biomechanically compatible to the anatomy of Indian people.
Non-Nutritive Bioactive Compounds in Pulses and Their Impact on Human Health: An Overview  [PDF]
Jagdish Singh, Partha Sarathi Basu
Food and Nutrition Sciences (FNS) , 2012, DOI: 10.4236/fns.2012.312218
Abstract: This review describes the non-nutritive biologically active components in grain legumes and discusses about the bioactivity of phenols, isoflavones, phytosterols, phytic acid, saponins, tannins, protease inhibitors and bioactive complex carbohydrates in different pulse grains. These bioactive components have wide ranging biological activities and conesquently many different targets and mechanism of action. The potential beneficial effect of these compounds especially their antioxidant properties and their role in the prevention of non-communicable chronic diseases such as coronary heart disease, stroke, cancer and diabetes has been discussed.
Characterization of positive solution to stochastic competitor-competitor-cooperative model
Partha Sarathi Mandal
Electronic Journal of Differential Equations , 2013,
Abstract: In this article we study a randomized three-dimensional Lotka-Volterra model with competitor-competitor-mutualist interaction. We show the existence, uniqueness, moment boundedness, stochastic boundedness and global asymptotic stability of positive global solutions for this stochastic model. Analytical results are validated by numerical examples.
From C*algebra extensions to CQMS, ${SU}_q(2)$, Podles sphere and other examples
Partha Sarathi Chakraborty
Mathematics , 2002,
Abstract: We construct compact quantum metric spaces (CQMS) starting with some C*algebra extension with a positive splitting. As special cases we discuss the case of Toeplitz algebra, quantum SU(2) and Podles sphere.
C*-algebra generated by projections
Partha Sarathi Chakraborty
Mathematics , 2003,
Abstract: The universal C*-algebra generated by n projections has been described. As an immediate corollary one obtains structure theorem for a pair of projections and the solution to an associated index problem. This puts the study of a pair of projections in the proper perspective of noncommutative geometry.
Metrics On The Quantum Heisenberg Manifold
Partha Sarathi Chakraborty
Mathematics , 2001,
Abstract: Compact quantum metric spaces are order unit spaces along with a Lip norm. On the order unit space of the selfadjoint elements of the dense subalgebra of smooth elements in the quantum Heisenberg manifold we construct Lip norms.
Chronic Disseminated Histoplasmosis
Ghosh Sanjay,Das Partha Sarathi
Indian Journal of Dermatology , 2003,
Abstract: A 55 year old HIV negative, controlled diabetic, male suffering from recurrent oropharyngeal ulcer for last 4 years, has recently developed papules and nodules predominantly on face and a few on upper trunk, arms and macrochilia for about last 3 months. Some papules resembled molluscum contagiosum. His palms showed significant erythema. Multiple ulcerative nodules were visible on tongue and buccal mucosa. Histopathology revealed intracellular yeast of Histoplasma capsulatum by PAS stain. The patient had no involvement of internal organs. He never traveled to endemic area but had exposure to a domestic a€ moinaa€ bird for last 6 years. The subject responded well to oral itraconazole 400 mg daily for 8 weeks followed by a maintenance therapy with 200 mg daily for another 8 weeks.
Exploration of Electrochemical Intermediates of the Anticancer Drug Doxorubicin Hydrochloride Using Cyclic Voltammetry and Simulation Studies with an Evaluation for Its Interaction with DNA
Partha Sarathi Guin,Saurabh Das
International Journal of Electrochemistry , 2014, DOI: 10.1155/2014/517371
Abstract: Electrochemical behavior of the anticancer drug doxorubicin hydrochloride was studied using cyclic voltammetry in aqueous medium using Hepes buffer (pH~7.4). At this pH, doxorubicin hydrochloride undergoes a reversible two-electron reduction with value ? ?mV (versus Ag/AgCl, saturated KCl). Depending on scan rates, processes were either quasireversible (at low scan rates) or near perfect reversible (at high scan rates). This difference in behavior of doxorubicin hydrochloride with scan rate studied over the same potential range speaks of differences in electron transfer processes in doxorubicin hydrochloride. Attempt was made to identify and understand the species involved using simulation. The information obtained was used to study the interaction of doxorubicin hydrochloride with calf thymus DNA. Cathodic peak current gradually decreased as more calf thymus DNA was added. The decrease in cathodic peak current was used to estimate the interaction of the drug with calf thymus DNA. Nonlinear curve fit analysis was applied to evaluate the intrinsic binding constant and site size of interaction that was compared with previous results on doxorubicin hydrochloride-DNA interaction monitored by cyclic voltammetry or spectroscopic techniques. 1. Introduction Anthracycline anticancer drugs are amongst the most active agents in oncology [1, 2], first recognized for their antibacterial properties in 1939. Their chemical characterization led to an increase in use after therapeutic value of their antineoplastic activity was described in the early 1960s. Two anthracyclines, daunomycin (daunorubicin) and doxorubicin hydrochloride (hydroxyl daunomycin or doxorubicin), were initially isolated from Streptomyces peucetius var. caesitue [3, 4] and exhibit the widest spectrum of antitumor activity [5, 6]. The presence of a side chain primary alcohol group in doxorubicin hydrochloride has important consequences in antitumor activity that makes it more valuable than other anthracyclines. Doxorubicin hydrochloride is used in the treatment of breast cancer, childhood solid tumors, soft tissue sarcomas, and aggressive lymphomas. However, its use is often hampered by cumulative dose-limiting cardiotoxicity resulting in cardiomyopathy and congestive heart failure that may be irreversible [7]. Though there is still some controversy with regard to their mode of action, anticancer activity or cytotoxic effects involve interaction with nuclear components, especially DNA and type-II topoisomerase [8, 9]. The anthracyclines contain a planar aglycone ring coupled with an aminosugar. The
The geometry of determinant line bundles in noncommutative geometry
Partha Sarathi Chakraborty,Varghese Mathai
Physics , 2008, DOI: 10.4171/JNCG/46
Abstract: This paper is concerned with the study of the geometry of determinant line bundles associated to families of spectral triples parametrized by the moduli space of gauge equivalent classes of Hermitian connections on a Hermitian finite projective module. We illustrate our results with some examples that arise in noncommutative geometry.
On equivariant Dirac operators for $SU_q(2)$
Partha Sarathi Chakraborty,Arupkumar Pal
Mathematics , 2005,
Abstract: We explain the notion of minimality for an equivariant spectral triple and show that the triple for the quantum SU(2) group constructed by Chakraborty and Pal is minimal. We also give a decomposition of the spectral triple constructed by Dabrowski et al in terms of this minimal triple.
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