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Search Results: 1 - 10 of 144894 matches for " Palkar Mahesh B "
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RATIONAL DESIGN OF ANTIBACTERIAL THIENOPYRIMIDINES BY 2D-QSAR STUDY
Mulla Jameel Ahmed S,Palkar Mahesh B,Maddi Veeresh S,Khazi Imtiyaz Ahmed M
Journal of Drug Delivery and Therapeutics , 2012,
Abstract: QSAR studies were performed on a set of 43 analogs of thienopyrimidine using V-Life Molecular Design Suite (MDS 3.5) QSAR plus module by using Multiple Linear Regression (MLR) and Partial Least Squares (PLS) Regression methods against a gram positive (S.aureus) and a gram negative (E.coli) bacteria. MLR method has shown a very promising prediction results in both S.aureus and E.coli. QSAR model was generated by a training set of 34 molecules with correlation coefficient (r2) of 0.9849, 0.8719, significant cross validated correlation coefficient (q2) of 0.8881, 0.7811 and F test of 40.4301, 40.4768 respectively. In the selected descriptors, alignment independent descriptors such as T_C_C_7, T_N_O_3, T_2_N_1, T_N_O_1, T_O_O_7 and T_N_Cl_4 were the most important descriptors in predicting antibacterial activity.
Comparative study of proton pump inhibitors on dexamethasone plus pylorus ligation induced ulcer model in rats
Thippeswamy A. H. M.,Sajjan M,Palkar M,Koti B
Indian Journal of Pharmaceutical Sciences , 2010,
Abstract: The present study was designed to compare ulcer protective effect of proton pump inhibitors viz. omeprazole, rabeprazole and lansoprazole against dexamethasone plus pylorus ligation induced ulcer model. Dexamethasone (5 mg/kg) was used as an ulcerogen. Dexamethasone suspended in 1% CMC in water was given orally to all the rats 15 min after the pylorus ligation. Omeprazole (20 mg/kg), rabeprazole (20 mg/kg), and lansoprazole (20 mg/kg) were administered by oral route 30 min prior to ligation was used for ulcer protective studies, gastric secretion and mucosal studies. Effects of proton pump inhibitors were determined by the evaluation of various biochemical parameters such as ulcer index, free and total acidity, gastric pH, mucin, pepsin and total proteins. Oral administration of proton pump inhibitors showed significant reduction in gastric acid secretion and ulcer protective activity against dexamethasone plus pylorus ligation induced ulcer model. The % protection of omeprazole, rabeprazole and lansoprazole was 84.04, 89.36 and 79.78, respectively. Rabeprazole significantly inhibited the acid-pepsin secretion and increased the gastric mucin secretion. The observations made in the present study suggest that rabeprazole is the most effective gastric antisecretory and ulcer healing agent as compared to omeprazole and lansoprazole.
Animal Husbandry Practices of Organic Farmers: An Appraisal
Subrahmanyeswari,B and Mahesh Chander
Veterinary World , 2008,
Abstract: In Uttarakhand organic farming is being promoted through a special institution i.e. Uttarakhand Organic Commodity Board (UOCB) through registering the farmers and orienting them towards organic farming. Organic farmers currently practicing and marketing only organic crop products. However, their livestock production practices are also similar to recommended organic standards. Hence, to document their livestock production practices, a total of 180 registered organic farmers selected through multistage sampling technique studied during 2006-07. Cent percent of registered organic farmers were involved in mixed farming enterprises and most of them were with more than one livestock species (farm diversity). The breeds maintained by these farmers were of indigenous and they were raising livestock on the inputs met on farm and from the farms of similar agro-ecological regions. In view of the raising demand for organic livestock products locally as well as internationally, the organic promoting agencies have to focus on orienting these farmers towards stringent organic livestock standards so as to enable them to meet the organic livestock products demand locally as well as internationally. [Veterinary World 2008; 1(10.000): 303-305]
Properties of magnetite nanoparticles synthesized through a novel chemical route
Deepa Thapa,V. R. Palkar,M. B. Kurup,S. K. Malik
Physics , 2004,
Abstract: We have developed a simple precipitation route to synthesize magnetite (Fe3O4) nano-particles with controlled size without any requirement of calcination step at high temperatures. The study of these nano-particles indicates an enhancement in saturation magnetization with reduction in size down to ~10 nm beyond which the magnetization reduces. The latter is attributed to surface effects becoming predominant as surface to core volume ratio increases. From the view -point of applications, 10 nm size of magnetite particles seems to be the optimum.
Serial changes in acute phase proteins in cardiac surgery.
Palkar S,Taskar S
Journal of Postgraduate Medicine , 1988,
Abstract:
Application of Artificial Neural Networks to Real Estate Appraisals
Zachary Wong,Milam Aiken,Mahesh B. Vanjani
Asian Journal of Information Technology , 2012,
Abstract: Real estate price appraisal is inherently risky because of the reliance on a large quantity of subjective data. Many appraisals are based upon statistical multiple regression analysis, but the application of an artificial neural network can improve accuracy substantially. A study using data from 486 home sales in the Boston, Massachusetts area illustrates the advantages of the technique.
PRE-SERVICE TEACHERS’ BELIEFS ABOUT TEACHING ENGLISH TO PRIMARY SCHOOL CHILDREN
Mahesh B. Shinde,Tripti K. Karekatti
International Journal of Instruction , 2012,
Abstract: This paper is a part of an ongoing doctoral research on ‘Teacher Talk in ESL Classrooms’. The idea for this was gained through the hypothesis that teachers’ beliefs about English teaching may also mould their talk. The researcher intends here to analyse and comment on teachers’ English teaching beliefs. It is generally accepted that teaching is greatly affected by the belief systems of its practitioners-teachers. Teachers’ beliefs influence their consciousness, teaching attitude, teaching methods and teaching policies, and finally, learners’ development. Horwitz (1987) also states rightly that the formation of teachers’ educational beliefs in language teaching/ learning process will influence, though indirectly, on forming effective teaching methods and will bring about the improvement of learners’ language learning abilities. In Indian context, there is dearth of research evaluating teachers’ beliefs about English teaching. This study explores teachers’ beliefs regarding teaching English to children and tries to explore whether medium of instruction makes any difference in their beliefs. It also intends to determine what similar and different beliefs might be held by in-service teachers from two different mediums. A total of 100 pre-service teachers are the subjects of this study. In order to recognize these teachers’ specific beliefs in a more systematic way, a research instrument, The Questionnaire of Primary School Pre-service English Teachers’ Teaching Beliefs was developed. Almost all of these pre-service teachers expected to have training regarding how to make their talk effective and relevant in classrooms.
FRACTURE ANALYSIS OF EXHAUST MANIFOLD STUD OF MAHINDRA TRACTOR THROUGH FINITE ELEMENT METHOD (FEM) – A PAST REVIEW
MAHESH M. SONEKAR,,DR. SANTOSH B. JAJU
International Journal of Engineering and Technology , 2011,
Abstract: The present paper is a review of the past work done in the field of analysis on fracture of various casting components, engine parts and other area of applications using FEM (ANSYS). Failures were observed even after designing the components with maximum stress value well below yield / ultimate stress. Later it was concluded that the failure is because of variation of load with respect to “time” not being taken in to account. Tests were then carried out for time varying loads. Results proved that the component fails at values below yield stress when subjected to time varying load. It was also observed that below a specific stress value components were not failing at all. This stress value was termed as endurance limit. For example yield stress for general steel is around 250 N/mm2 and endurance limit 160 N/mm2.In general while using FEM technique for failure analysis, a finite element routine would be first used to calculate the static and dynamic displacement and stresses under the maximum compression and tension loading, which were then used for critical points evaluation. Calculation based on failure life and accurate loading histories permit components to be optimized for durability without the need for expensive and time-consuming testing of series of prototypes. According to the various literature reviews on failure analysis, FEA based fatigue analysis of metals (iron, steel, aluminium etc.), and mostly the casted components has been well established. But same is not true with non metals (like polymers etc.). The nonlinear fatigue behavior is not yet completely understood and still in research phase. This paper proposes the use of Finite Element Method (FEM) with ANSYS and ABAQUS as one of the helping software for better result analysis in most of the failure applications.
Evaluation of Antioxidant and Antimicrobial Properties of Ixora brachiata Roxb
Mahesh Poojari,Subrahmanya Padyana,B. Raghavendra Rao
Journal of Chemistry , 2009, DOI: 10.1155/2009/962753
Abstract:
Effect of Changing Environments on Microstructure of HDPE Polymer  [PDF]
S. Bal, D. Mahesh, T.K. Sen, B.C. Ray
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2007, DOI: 10.4236/jmmce.2007.61001
Abstract: The analysis of environmental effects on microstructure of HDPE polymers were done according to their mechanical behavior obtained from tensile, impact and microhardness testing and thermograms obtained from DSC. The samples were conditioned under three different kinds of humidity and temperature environment. With increase in conditioning time, the variations of tensile strength, impact, microhardness were observed to be nonlinear in nature. The high values are possibly due to polymerization such as cross-linking. The low values may be attributed by depolymerization mechanism such as chain scission and bond breakage. The variation of data is due to more physical damage of the polymer because of unequal expansion of the surface. The refrigeration also affects the crystalline regions by changing free volume. Again rearrangement of end groups in the lamella through partial melting and recrystallization are observed due to thermal conditioning and thermal shock.
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