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Search Results: 1 - 10 of 434043 matches for " Pablo Méndez "
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Antropología y conflicto: una reflexión de campo
Pablo Méndez Gallo
Nómadas , 2003,
Abstract:
INSOSTENIBILIDAD DEMOCRáTICA. DE LA SOCIEDAD DEL RIESGO A LA SOCIEDAD DE LA TURBULENCIA
Pablo Méndez Gallo
Nómadas , 2010,
Abstract: El planeta no es infinito: de acuerdo al vigente modelo de riqueza puramente extractiva, los recursos se agotan y el propio planeta se agota. La sostenibilidad se presenta como un parche intermedio, para salvar el modelo económico (insostenible) y para salvar el planeta, al mismo tiempo -capitalismo verde-. Inútil, según todas las previsiones. Lo mismo ocurre en el terreno de la política: concebido el ciudadano como mero instrumento comercial, sometido a todo tipo de tropelías en beneficio de un sacrosanto modelo político-económico elevado al rango de dogma, la democracia no puede sino rendirse a los pies de los grandes flujos de poder que se establecen al margen de los gobiernos, del interés común. En este mismo sentido, la Democracia, como tal sistema de organización del bien común, deja de ser un refugio para convertirse en un desierto. La materialización del riesgo, esto es, la turbulencia, se convierte en el fenómeno atmosférico -climático y político- característico de las sociedades contemporáneos. La certidumbre ha muerto, y con ella, la vida en común y la democracia.
Assortment of GABAergic Plasticity in the Cortical Interneuron Melting Pot
Pablo Méndez,Alberto Bacci
Neural Plasticity , 2011, DOI: 10.1155/2011/976856
Abstract: Cortical structures of the adult mammalian brain are characterized by a spectacular diversity of inhibitory interneurons, which use GABA as neurotransmitter. GABAergic neurotransmission is fundamental for integrating and filtering incoming information and dictating postsynaptic neuronal spike timing, therefore providing a tight temporal code used by each neuron, or ensemble of neurons, to perform sophisticated computational operations. However, the heterogeneity of cortical GABAergic cells is associated to equally diverse properties governing intrinsic excitability as well as strength, dynamic range, spatial extent, anatomical localization, and molecular components of inhibitory synaptic connections that they form with pyramidal neurons. Recent studies showed that similarly to their excitatory (glutamatergic) counterparts, also inhibitory synapses can undergo activity-dependent changes in their strength. Here, some aspects related to plasticity and modulation of adult cortical and hippocampal GABAergic synaptic transmission will be reviewed, aiming at providing a fresh perspective towards the elucidation of the role played by specific cellular elements of cortical microcircuits during both physiological and pathological operations. 1. Introduction The cerebral cortex (which includes the hippocampus, the entorhinal cortex, the piriform cortex, and the neocortex) is the origin of the most sophisticated cognitive functions and complex behaviors. Indeed, the constant computation of incoming sensory information is dynamically integrated to provide a coherent representation of the world, elaborate the past, predict the future, and ultimately develop a consciousness and the self. In particular, the specific activity states of intricate cortical networks often produce a wide range of rhythmic activities, believed to provide the computational substrate for different aspects of cognition and various behaviors [1, 2]. Cortical oscillations range from slow-wave activity (<1?Hz) to ultrafast oscillations (>100?Hz), with several intermediate rhythms (e.g., theta, beta gamma), each of which is considered to underlie specific cognitive aspects, such as non-REM sleep (slow-waves), sensory integration (gamma), working memory (theta), and motor planning (beta) [1]. Importantly, inhibitory neurons were proposed to play a fundamental role in the genesis of most of these rhythms [3–13] through the specialized activity of their GABAergic synapses [7–10]. In fact, it is noteworthy that malfunctioning of specific GABAergic circuits is often indicated as a leading
Apoyo Social Percibido en Adolescentes Infractores de Ley y no Infractores
Méndez,Pablo; Barra,Enrique;
Psykhe (Santiago) , 2008, DOI: 10.4067/S0718-22282008000100006
Abstract: this study compared perceived social support in two groups of 14 to 18 years old male adolescents, from the city of linares (chile), 53 law offenders and 53 non offenders. they were matched on several sociodemographic variables in order to equate both groups. the questionnare that was administered included questions about social network size, total support and four dimensions: emotional, advice, instrumental and reciprocity. results showed significant differences between groups: non offenders showed a higher level of support network size, and higher levels on each dimension of support, and support perceived in the family, in comparison to law offenders.
Apoyo Social Percibido en Adolescentes Infractores de Ley y no Infractores Perceived Social Support in Adolescent Law Offenders and non Offenders
Pablo Méndez,Enrique Barra
Psykhe (Santiago) , 2008,
Abstract: Este estudio comparó la percepción de apoyo social de dos grupos de adolescentes varones entre 14 y 18 a os de la ciudad de Linares (Chile): 53 infractores de ley y 53 no infractores, los cuales fueron pareados en diversas variables sociodemográficas para hacerlos equivalentes. El cuestionario utilizado incluyó preguntas sobre tama o de la red de apoyo, apoyo total y las dimensiones emocional, consejo, instrumental y reciprocidad. Se encontraron diferencias significativas entre los grupos, de modo que el grupo no infractor mostró un mayor tama o de la red de apoyo, y mayores niveles en cada una de las dimensiones de apoyo y apoyo percibido familiar, en comparación con el grupo de infractores. This study compared perceived social support in two groups of 14 to 18 years old male adolescents, from the city of Linares (Chile), 53 law offenders and 53 non offenders. They were matched on several sociodemographic variables in order to equate both groups. The questionnare that was administered included questions about social network size, total support and four dimensions: emotional, advice, instrumental and reciprocity. Results showed significant differences between groups: non offenders showed a higher level of support network size, and higher levels on each dimension of support, and support perceived in the family, in comparison to law offenders.
Piomiositis primaria por Staphylococcus aureus meticilino-resistente proveniente de la comunidad
Jozefkowicz,Mariela; Jorrat,Pablo; Méndez,José;
Archivos argentinos de pediatr?-a , 2008,
Abstract: primary pyomyositis is an acute or subacute bacterial infection of skeletal muscle characterized by the formation of intramuscular localized abscess without a previous adjoining or remote infection. although it is not frequent in our population, it is increasing because of community-acquired methicilin-resistant staphylococcus aureus (ca-mrsa) emergency. for an early diagnosis and to avoid secondary complications a high degree of clinical suspicion is required. we report a case of primary pyomyositis in a boy without an underlying condition or previous infection.
La Formación de los Nacionalismos; Política y Metáforas
Pablo Méndez Gallo,Inmaculada Jauregui
Revista Observaciones Filosóficas , 2006,
Abstract: Este artículo que pretende reencuadrar el conflicto nacionalista de aquellas naciones sin estado dentro de un marco conflictivo inherente a la propia concepción del estado moderno. Dentro de esta nueva perspectiva, los conflictos nacionalistas deben entenderse dentro del contexto en el cual están inmersos, como es el de la nación-estado, organismo que tiene como primer movimiento un ejercicio de violencia: El estado empieza cuando se obliga a convivir a grupos nativamente separados . El mito de la nación-estado, como se verá, tergiversa los conceptos al querer fundar la nación estatal sobre una unidad territorial, lingüística y racial que oculta justamente la pluralidad y la diversidad que dio origen al Estado, buscando una supuesta solidaridad e intimidad. El estado-nación moderno llega a fundirse con los otros que le han constituido, confundiéndose y confundiendo igualmente las pluralidades que lo forman. Finalmente, desde una perspectiva psico-cultural, también se examinara cómo el proceso de humanización del ser humano viene dado por un pasaje de lo natural a lo cultural, atendiendo de modo particular a la evolución política tenida lugar en Occidente 'de lo político a lo social'.
IL28B SNPs rs12979860 and rs8099917 Are Associated with Inflammatory Response in Argentine Chronic HCV Patients  [PDF]
Andrés Machicote, Diego Flichmann, Eloisa Arana, Silvia Paz, Hugo Fainboim, Leonardo Fainboim, Pablo M. Fernández
International Journal of Clinical Medicine (IJCM) , 2018, DOI: 10.4236/ijcm.2018.92009
Abstract: Background: Hepatitis C virus (HCV) is a major cause of chronic liver disease, including cirrhosis and liver cancer. The aim of our study was to determine whether IL28B single nucleotide polymorphisms (SNPs) rs12979860 and rs8099917 can be considered a prognostic host factor in untreated chronic HCV patients. Methods: We set up a real-time Allele Specific PCR amplification to determine the allele present in each polymorphic site, and statistically grouped and compared this result with clinical data. Results: We determined rs12979860 and rs8099917 genotype and allele frequencies in a single cohort of untreated chronically HCV-infected patients. We found significant associations between higher inflammatory activity, measured as ALT levels or METAVIR scores and rs12979860 CC (P = 0.0013 and P = 0.0033, respectively) and rs8099917 TT (P = 0.0005 and P = 0.0264, respectively) genotypes. Interestingly, considering both genotypes together, we also found association with ALT levels (P = 0.0003; OR = 5.125) or METAVIR scores (P = 0.0038; OR = 5.179), suggesting and additive effect on liver inflammation in these patients. Conclusion: we show association between hepatic inflammatory activity in a single Argentinean untreated chronically HCV cohort and SNPs located in the interferon lambda gene region. The studied polymorphisms, together with further innate and adaptive immune responses, clearly play a role in modulating the HCV infected patients outcome, contributing to hepatic inflammation and possible fibrosis/cirrhosis.
Familia: bisagra en el divorcio entre educación y sociedad
Inmaculada Jáuregui Balenciaga,Pablo Méndez Gallo
Nómadas , 2006,
Abstract:
Evolución y desarrollo de la medicina medieval en occidente
Pablo Pérez Méndez, and Juan José Varela Tembra
Oceánide , 2009,
Abstract: This paper examines the evolution and development of medieval medicine in the West from a diachronic and historical perspective. In particular, we focus on two poles or axes, the Muslim and the Christian as a basis of the birth of modern medicine; as a synthesis of both traditions. After framing its origin, we define its area of influence and its subsequent interaction with the establishment of the School of Salerno. The next issue outlines the contributions of both lines and borrowings to other sciences such as chemistry, pharmacy and botany. The emergence of the first hospitals and their subsequent widespread establishment in order to provide attention to various plagues and ailments helps us to complete this contribution which marks a turning point in the history of medicine.
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