oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Search Results: 1 - 10 of 586 matches for " PAREGOWDA NAGE GOWDA "
All listed articles are free for downloading (OA Articles)
Page 1 /586
Display every page Item
Titrimetric and spectrophotometric assay of felodipine in tablets using bromate–bromide, Methyl Orange and Indigo Carmine reagents
KANAKAPURA BASAVAIAH,UMAKANTHAPPA CHANDRASHEKAR,PAREGOWDA NAGE GOWDA
Journal of the Serbian Chemical Society , 2005,
Abstract: Three new methods based on titrimetric and spectrophotometric techniques are described for the determination of felodipine (FLD) in the bulk drug and in tablets using a bromate–bromide mixture and two dyes, Methyl Orange and Indigo Carmine. In the titrimetric method (method A), the drug solution was treated with a measured excess of the bromate–bromide mixture in acid medium, and after the reaction was judged to be complete, the unreacted bromine was determined iodometrically. The two spectrophotometricmethods are based on the bromination of the drug with a known excess of the bromate–bromide mixture under acidic conditions followed by the estimation of the surplus bromine by reaction with either Methyl Orange (Method B) or Indigo Carmine (Method C), and measuring the absorbance at 520 nm or 610 nm, respectively. In all the methods, the amount of reacted bromine corresponds to the drug content. The titrimetric procedure is applicable for between 6–15 mg and the reaction stoichiometry was found to be 1:1 (drug: BrO3-). The systems obey Beer’s law between 0.12 – 0.87 mgml-1 and 0.5 – 6.0 mgml-1 formethods B and C, respectively. The limits of detection and quantification are reported for both the spectrophotometricmethods. The methods could usefully be applied to routine quality control of pharmaceutical formulations containing FLD. Statistical comparison of the results with the reference method shows excellent agreement and indicates no significant difference in accuracy and precision.
Simple and practicable methods for the determination of astemizole in pharmaceuticals using bromate-bromide and two dyes
Nagegowda, Paregowda;Basavaiah, Kanakapura;
Journal of the Brazilian Chemical Society , 2005, DOI: 10.1590/S0103-50532005000500022
Abstract: one titrimetric and two spectrophotometric methods, which are simple and sensitive, are described for the determination of astemizole (ast) in bulk drug and formulations. the methods use bromate-bromide mixture and two dyes, methyl orange and indigo carmine. in titrimetry (method a), astemizole is treated with a known excess of bromate-bromide mixture in acid medium and after the bromination reaction is ensured to be complete, the residual bromine is back-titrated iodometrically. in spectrophotometric methods, the excess of bromine is estimated by treating it with a fixed amount of either methyl orange (method b) or indigo carmine (method c) and measuring the change in absorbance either at 520 or 610 nm. in all the methods, the amount of bromate reacted corresponds to the drug content. titrimetric method is applicable over 4-16 mg range and the calculations are based on a 1:0.666 (ast: bromate) reacting ratio. in spectrophotometry, the calibration graph is found to be linear over 0.5-4.0 μg ml-1 (method b) and 1.25 12.5 μg ml-1 (method c) with molar absorptivity values of 6.6 x 104 l mol-1 cm-1 and 2.1 x 104 l mol-1 cm-1, respectively. the limits of detection and quantification are reported for methods b and c. the statistical evaluation of the methods was examined by determining intra-day and inter-day precision. the methods were applied to the determination of ast in tablets and syrups and the results were found to agree well with the label claim. the accuracy and reliability of the methods were further ascertained by parallel determination by a reference method and by calculating the student's t-value and f-value at the 95% confidence level, and by recovery studies using standard addition technique.
Titrimetric, spectrophotometric and kinetic methods for the assay of atenolol using bromate–bromide and methyl orange
KANAKAPURA BASAVAIAH,UMAKANTHAPPA CHANDRASHEKAR,PAREGOWDA NAGEGOWDA
Journal of the Serbian Chemical Society , 2006,
Abstract: Three new methods have been developed for the determination of atenolol in bulk drug and in tablet formulation. The methods are based on the oxidation–bromination reaction of the drug by bromine, generated in situ by the action of acid on a bromate–bromide mixture. In the titrimetric method, the drug is treated with a known excess of bromate–bromide mixture in hydrochloric acid medium, followed by the determination of the unreacted bromine iodometrically. The spectrophotometric method involves the addition of a measured excess of bromate–bromide reagent in hydrochloric acid medium to atenolol, and after ensuring the reaction had gone to completion, the unreacted bromine is treated with a fixed amount of methyl orange, and absorbance measured at 520 nm. The absorbance was found to increase linearly with increasing concentration of atenolol. The kinetic method depends on the existence of a linear relationship between the concentration of the drug and the time of the oxidation–bromination reaction, as indicated by the bleaching of methyl orange acid colour. The working conditions were optimized. The titrimetric method is based on a 1:1 reaction stoichiometry (atenolol:bromate) and is applicable over the 3–20 mg range. The spectrophotometric method permits micro determination of the drug (0.5–4.0 mg ml-1)with an apparentmolar absorptivity of 4.13x104 lmol-1 cm-1 and detection limit of 0.07 mg ml-1. The kinetic method is applicable in the concentration range 5–25 mg ml-1 with a detection limit of 3.72 mg ml-1. The proposed methods were successfully applied to the determination of atenolol in tablet preparations with mean recoveries of 97.63 to 101.78 %. The reliability of the assay was established by parallel determination by the reference method and by recovery studies using the standard addition technique.
Idiopathic Intracranial Hypertension in Sickle Cell Disease: A Paediatric Case Report  [PDF]
Bharath Gowda, Sanjay Sahi
Neuroscience & Medicine (NM) , 2013, DOI: 10.4236/nm.2013.44033
Abstract:

In this article, we present the case of a 12-year-old girl with sickle cell disease (SCD), who presented with the severe headache. She had bilateral 6th cranial nerve palsy and papilloedema. The common sickle cell-related vascular causes of headache were ruled out by neuro-imaging. She then had a lumbar puncture and was diagnosed with idiopathic intracranial hypertension (IIH). This case demonstrates that IIH can affect younger children with SCD and should form a part of differential diagnosis when investigating causes of headache in SCD.

La2O3 Catalyzed Oxidation of Alcohols  [PDF]
Ravikumar R. Gowda, Debashis Chakraborty
International Journal of Organic Chemistry (IJOC) , 2011, DOI: 10.4236/ijoc.2011.12008
Abstract: A variety of aromatic, aliphatic and conjugated alcohols were transformed to the corresponding carboxylic acids and ketones with a quantitative conversion in high yields with 70% t-BuOOH solution is water in the presence of catalytic amounts of La2O3. This method possesses a wide range of capabilities since it can be used with other functional groups which may not tolerate oxidative conditions, involves fairly simple method for work-up, exhibits chemoselectivity and proceeds under ambient conditions. The resulting products are obtained in good yields within reasonable time.
Energy and Throughput Optimized, Cluster Based Hierarchical Routing Algorithm for Heterogeneous Wireless Sensor Networks  [PDF]
Mahanth K Gowda, K. K. Shukla
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2011, DOI: 10.4236/ijcns.2011.45038
Abstract: We propose a novel cluster based distributed routing algorithm in a generalized form for heterogeneous wireless sensor networks. Heterogeneity with respect to number/types of communication interfaces, their data rates and that with respect to energy dissipation model have been exploited for energy and throughput efficiency. The algorithm makes routing assignment optimized for throughput and energy and has a complexity of N/K*logN+k2logk approximately, where N is the number of nodes and k is the number of kcluster heads. Performance experiments confirm the effectiveness of throughput and energy optimizations. The importance of choosing an optimal cluster radius has been shown. The energy consumption in the network scales up well with respect to the network size.
Intra-Scrotal Extra-Testicular Leiomyoma, a Common Mesenchymal Tumor at a Rare Site: Emphasizing the Need for Awareness of Its Occurrence  [PDF]
Kiran Krishne Gowda, Raman Narayana Rao
Open Journal of Pathology (OJPathology) , 2015, DOI: 10.4236/ojpathology.2015.51002
Abstract: Leiomyoma is a benign tumor of smooth muscles. Leiomyoma originating from the scrotum is a rare entity. We report a case of 53-year-old African male who presented with a 3 cm lump in the right side of scrotum. Clinically, it was provisionally diagnosed as sebaceous cyst and was excised. The histopathology showed a leiomyoma. There was no cytological atypia or mitosis. The patient also had squamous papilloma over left gluteal region.
Effect of Particulate Reinforcement on the Mechanical Properties of Al2024-WC MMCs  [PDF]
K. Punith Gowda, J. N. Prakash, Shivashankare Gowda, B. Satish Babu
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2015, DOI: 10.4236/jmmce.2015.36049
Abstract: The present work reveals the study of mechanical properties of Al2024-Tungsten carbide MMCs containing tungsten carbide (WC) particulates. The reinforcing particulates in the Al2024 alloy were varied from 0% to 5% by weight. The vortex method of cast production was employed to fabricate the MMCs, in which the reinforcement was poured into the vortex created by stirring the molten metal by means of a mechanical agitator. The composite so produced was subjected to a series of mechanical tests. The results of this study revealed that as the tungsten carbide particle content was increased, there were significant increases in the ultimate tensile strength, hardness and young’s modulus, compressive strength, accompanied by a reduction in its ductility. An attempt is made in the paper to provide explanations for these phenomena.
Development of animal drawn rotary tiller
S. M. Nage,B. P. Mishra,A. K. Dave,J. S. Nikhade
Journal of Engineering and Applied Sciences , 2011,
Abstract: Rotary tiller generally refers to breaking down soil aggregates into ultimate soil particles. The degree of clod breaking depends on moisture content, tillage implements and intensity of clod breaking. One unit of animal drawn rotary tiller with L - shapes of blades was developed and fabricated at workshop of Faculty of Agricultural Engineering, Raipur. The effective field capacity of animal drawn rotary tiller (18 blades) was found 0.12 ha/h at a forward speed of 2.5 km/h. The field efficiency of 62.85% was observed during the field performance. The draft requirement of the developed animal drawn rotary tiller is 378 N. Mean Mass Diameter (MMD) of soil clod size was found 28.42 mm. The operational cost was found 384 Rs/ha.
Path Coefficient Analysis of Buffalo Production in Buldana District of Maharashtra
K U Bidwe,S D Chavan,S P Nage and P H Bansod
Veterinary World , 2009,
Abstract: A study entitled “Decomposition analysis of buffalo production in Buldana District was undertaken to ascertain the technological changes in term of breeding, feeding, housing, milking and calf management practices of buffalo. The path coefficient analysis of this study clearly demonstrated that daily milk production in buffaloes was influenced substantially by a single factor i.e management index. A combination of all the management practices in the form of overall management status on the rearing were responsible to influence the daily milk yield. However, rearing of good potential animals, feeding of sufficient amounts of dry and green fodder with required amount of concentrates to fulfill the nutritional requirements could favour the milk production in buffaloes. All these factors exhibited positive direct effect on milk production. The indirect effects were also found in positive direction, resulting a positive significant correlation for these factors. [Vet. World 2009; 2(3.000): 103-104]
Page 1 /586
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.