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Search Results: 1 - 10 of 317130 matches for " P; González Casta?o "
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Hemangioma capilar retiniano y enfermedad de von Hippel-Lindau: implicaciones diagnósticas y terapéuticas
Salazar,R.; González-Castao,C.; Rozas,P.; Castro,J.;
Archivos de la Sociedad Espa?ola de Oftalmología , 2011, DOI: 10.4321/S0365-66912011000700004
Abstract: clinical case: man carrier of the von hippel-lindau (vhl) gene, with long-onset loss of vision in left eye. he had a retinal capillary hemangioma (hcr) and diffuse cystic edema in posterior pole. the systemic study revealed bilateral kidney tumors. laser photocoagulation was performed which produced a subretinal and vitreous hemorrhage that required vitrectomy. discussion: retinal capillary hemangioma (hcr) is the earliest and most frequent manifestation of the von hippel-lindau disease. its detection requires it to be treated early and to rule out other visceral lesions. laser photocoagulation is the most recommended treatment of small-size hcr. the most frequent complications are vitreous and subretinal haemorrhages.
Hemangioma capilar retiniano y enfermedad de von Hippel-Lindau: implicaciones diagnósticas y terapéuticas Retinal capillary hemangioma and von Hippel-Lindau disease: diagnostic and therapeutic implications
R. Salazar,C. González-Castao,P. Rozas,J. Castro
Archivos de la Sociedad Espa?ola de Oftalmología , 2011,
Abstract: Caso clínico: Varón con disminución de visión en ojo izquierdo de larga evolución. Portador del gen de von Hippel-Lindau (VHL). Presenta hemangioma capilar retiniano (HCR) y edema quístico difuso en polo posterior. El estudio sistémico revela la existencia de masas renales bilaterales. Se inicia fotocoagulación con láser argón, produciéndose hemorragia subretiniana y hemorragia vítrea que precisó vitrectomía. Discusión: El HCR constituye la manifestación más frecuente y precoz en la enfermedad de VHL. Su detección obliga a su tratamiento precoz, así como a descartar otras lesiones viscerales. La fotocoagulación láser es el tratamiento de elección en el HCR de peque o tama o. Entre sus complicaciones destaca la hemorragia vítrea y subretiniana. Clinical case: Man carrier of the von Hippel-Lindau (VHL) gene, with long-onset loss of vision in left eye. He had a retinal capillary hemangioma (HCR) and diffuse cystic edema in posterior pole. The systemic study revealed bilateral kidney tumors. Laser photocoagulation was performed which produced a subretinal and vitreous hemorrhage that required vitrectomy. Discussion: Retinal capillary hemangioma (HCR) is the earliest and most frequent manifestation of the von Hippel-Lindau disease. Its detection requires it to be treated early and to rule out other visceral lesions. Laser photocoagulation is the most recommended treatment of small-size HCR. The most frequent complications are vitreous and subretinal haemorrhages.
Metástasis coroidea de carcinoma renal
Castro Navarro,J; Se?aris González,A; González Rodríguez,CM; Rozas Reyes,P; González Castao,C;
Archivos de la Sociedad Espa?ola de Oftalmología , 2004, DOI: 10.4321/S0365-66912004001200011
Abstract: case report: a fifty-two year-old man who came to our emergency room because of gradual loss of vision in his right eye. he had suffered right nefrectomy for renal cell carcinoma seven years previously and pneumectomy for metastasis in his right lung three months ago. in the fundus examination a choroidal mass was found in his right eye, suggesting metastasis. treatment was enucleation of the affected eye. during the first year there was no progression, but in the last six months it has re-appeared. discussion: choroidal metastasis of renal cell carcinoma is rare and can appear years after treating the primary tumour. its symptoms are variable, and its shape is not very characteristic so it can be difficult to make a differential diagnosis.
Resultados de la cirugía del agujero macular con diferentes técnicas de tratamiento
Villota-Deleu,E.; Castro-Navarro,J.; González-Castao,C.; Pérez-Carro,G.;
Archivos de la Sociedad Espa?ola de Oftalmología , 2006, DOI: 10.4321/S0365-66912006001000005
Abstract: purpose: to compare the effectiveness, efficiency and complications of three different surgical techniques employed for the treatment of macular holes between 1998 -2004 in our health care centre. methods: a retrospective, comparative, and non-randomized study of 131 eyes with macular holes, stage iii and iv, treated with three different surgical techniques was performed. vitrectomy was performed in 25 eyes (group 1). vitrectomy was associated with internal limiting membrane peeling in 19 eyes (group 2), and in the remaining 87 eyes, the peeling of the retinal internal limiting membrane was assisted with indocyanine green (icg) (group 3). the concentrations of icg used were 5%, 2.5% and 0.5%. we compared the anatomic and functional results, and the complications which occurred. results: the overall anatomic success rate was 88.4% (114 eyes), and it was higher in group 3 (90.6%). a visual acuity improvement was achieved in 63.6% of eyes; however there were no significant differences between the groups studied. the most important complications included cataracts (51.9%), increase in intra-ocular pressure (37.2%), retinal detachment (7.8%) and retinal pigment epithelial changes (7%). these pigment epithelial changes were associated with the use of icg-assisted peeling (p<0.05), but there was no correlation between the changes and the concentration of icg employed. the hole size had an inverse correlation with initial and final visual acuity. an epi-retinal membrane was associated with better visual acuities and higher anatomic success. conclusions: in our experience, the use of icg-assisted internal limiting membrane peeling in macular hole surgery improves the anatomic success, but may lead to retinal pigment epithelial changes.
Multilayers coatings for corrosion resistance enhancement of chromium electrodeposits
Benaben, P.J.;Casta?eda, F.;Anta?o, R.;Morales, J.;Terol, I.;Torres-González, J.;
Superficies y vacío , 2012,
Abstract: chromium multilayers coatings were obtained from three different bath solutions, they were prepared using a square wave current function. two temperatures were studied, 35°c and 55°c varying current density 10 and 70 adm-2. the combinations of different microstructures were studied: columnar and equiaxial. the chromium multilayers were characterized by scanning electron microscopy (sem), x-ray diffraction (xrd), and salt spray (fog) test. in general the coatings are microcracked, have small grain size and show an unexpected very good corrosion resistance, in some cases coatings do not form red rust even after 700 h of salt spray test.
Resultados de la cirugía del agujero macular con diferentes técnicas de tratamiento Outcomes of macular hole surgery using three different surgical techniques
E. Villota-Deleu,J. Castro-Navarro,C. González-Castao,G. Pérez-Carro
Archivos de la Sociedad Espa?ola de Oftalmología , 2006,
Abstract: Objetivo: Comparar la efectividad, eficiencia y complicaciones de las tres técnicas quirúrgicas empleadas en el tratamiento del agujero macular en el período 1998-2004 en nuestro centro. Métodos: Estudio retrospectivo, comparativo, intervencionista y no aleatorizado de 131 ojos con agujero macular idiopático en estadío III y IV, operados con tres técnicas. En 25 ojos se realizó vitrectomía simple (grupo 1), en 19 ojos se asoció rexis de la membrana limitante interna (MLI) (grupo 2), y en 87 ojos esta rexis se llevó a cabo previa tinción con verde de indocianina (ICG) (grupo 3). Las concentraciones de ICG empleadas fueron del 5%, 2,5% y 0,5%. Se compararon la recuperación anatómica y funcional y las complicaciones en los distintos grupos. Resultados: El 88,4% (114 ojos) lograron la resolución anatómica, siendo superior en el grupo 3 (90,6%). La recuperación funcional se consiguió en el 63,6%. En ambos casos no existieron diferencias entre grupos. Las complicaciones más importantes fueron: cataratas post-cirugía (51,9%), aumento de PIO (37,2%), desprendimientos de retina (7,8%) y alteraciones del epitelio pigmentario (7%). Esta última se relacionó con el uso de ICG (p<0,05), sin encontrarse diferencias en las concentraciones empleadas. El tama o del agujero tuvo una correlación inversa con la agudeza visual (AV) inicial y post-quirúrgica. La presencia de membrana epirretiniana se asoció a mejores AV y a un mayor éxito anatómico. Conclusiones: En nuestra experiencia, la cirugía mejora la AV, siendo más efectiva si se asocia ICG para la rexis de la MLI. Sin embargo, esta tinción podría estar relacionada con las alteraciones del EPR encontradas. Purpose: To compare the effectiveness, efficiency and complications of three different surgical techniques employed for the treatment of macular holes between 1998 -2004 in our health care centre. Methods: A retrospective, comparative, and non-randomized study of 131 eyes with macular holes, stage III and IV, treated with three different surgical techniques was performed. Vitrectomy was performed in 25 eyes (group 1). Vitrectomy was associated with internal limiting membrane peeling in 19 eyes (group 2), and in the remaining 87 eyes, the peeling of the retinal internal limiting membrane was assisted with indocyanine green (ICG) (group 3). The concentrations of ICG used were 5%, 2.5% and 0.5%. We compared the anatomic and functional results, and the complications which occurred. Results: The overall anatomic success rate was 88.4% (114 eyes), and it was higher in group 3 (90.6%). A visual acuity improvement was achiev
Obtención de anticuerpos monoclonales contra IgA secretora humana
Méndez Pérez,Ivonne; Carlos Castao,Jhon; Otero Alfaro,Oscar; Lastre González,Miriam; Pérez Martín,Oliver; Sarracent Pérez,Jorge;
Revista Cubana de Medicina Tropical , 1999,
Abstract: in order to determine the iga levels in secretions, the authors engaged themselves to obtain monoclonal antibodies against this immunoglobulin and to show their possible utilization in the development of quantitation methods. 6 monoclonal antibodies were obtained: one against the secretoy component (sc) and five against the heavy-chain (hc) of iga. iga purified from human colostrum was used as immunogen (hc). the immunoglobulin isotypes (igg2a and igg1) were determined in 2 monoclonal antibodies, one against sc and the other against hc. polyacrylamide gel electrophoresis was performed in the presence of sodium dodecyl sulphate and b-mercapto-ethanol. immunotrasnference was also carried out to determine their specificity. secretory iga was detected in saliva specimens. the anti-sc monoclonal antibody obtained in the laboratory of the "pedro kourí" institiute of tropical medicine (ipk) was compared with a commercial one (sigma chemical co.), and a similar behaviour was observed. the monoclonal antibody against sc (ipk) was used to detect iga specific to lps ogawa in persons vaccinated with an attenuated strain of vibrio cholerae. marked differences were found between the levels before and after immunization. the anti-hc monoclonal antibody was utilized to make an elisa-like simulated system. the detection limit was 9.89 ng/ml.
Time to Progression of AFP (TPA) as a Predictor of Survival in Hepatocellular Carcinoma Treated with Sorafenib (SOR)  [PDF]
Maria Varela, Olegario Castao-Fernández, Marcelo Garrido, Lorena Blanco-García, Pablo Martínez-Camblor, Alicia Mesa-álvarez, Carmen Navascués, Valle Cadahía-Rodrigo, Rafael Menéndez de Llano, Ramon Pérez-álvarez, Maria Luisa González-Diéguez, Manuel Rodríguez
Journal of Cancer Therapy (JCT) , 2014, DOI: 10.4236/jct.2014.514133
Abstract: Background: The standard therapy in advanced hepatocellular carcinoma (HCC) is sorafenib (SOR), which has the inconvenience of toxicity and discontinuation. Patient selection and the use of early markers are critical for optimizing the potential benefit of SOR. Alpha-fetoprotein (AFP) has an established role in HCC prognosis. The objective was to evaluate whether AFP variation during SOR treatment reflects the lack of progression to SOR and can be used as a prognostic factor. Methods: AFP levels were prospectively analyzed in 114 patients to determine whether the time to progression of AFP (TPA) at 3 months had a prognostic value for survival. Results: Between July 2007 and October 2012, 114 patients were included (mean age 64 years, 97 male, 96 with cirrhosis). Etiology was alcohol 47 (41%) and hepatitis C virus (HCV) 31 (27%). According to the Barcelona Clinic Liver Cancer (BCLC) staging system: A (one case), B (24 cases) and C (89 cases). The Child-Pugh was Class A in 89 cases. The general condition of the patient according to ECOG-PS was 0 in 73 cases. The median duration of treatment was 5 months (3.47 - 6.53, 95% CI). The median overall survival (OS) was 9.23 months. The standard dose was maintained in 26 patients (22.8%). Sixty-seven percent of patients experienced at least one adverse event grade 3-4. The time to progression of AFP lower or higher than 3 months was an independent prognostic factor of OS (univariate and multivariate analysis): 8.10 vs. 18.85 months, P < 0.001. Conclusion: HCC treated with SOR with TPA > 3 months had longer OS, and TPA was an independent prognostic factor.
Conformación de una comunidad virtual de aprendizaje, a partir de un proceso de formación de maestros universitarios.
M.A. de Unigarro Gutiérrez,L.A. Castao González,G. Mestre Mogollón,M.P. Prado Brand
RED : Revista de Educación a Distancia , 2007,
Abstract: La profesión docente en la sociedad de la información, nuevas dimensiones: La ética del trabajo.
Comunicar la responsabilidad social, una opción de éxito empresarial poco explorada
Castao González,Esther Julia;
Revista Lasallista de Investigación , 2011,
Abstract: this paper proposes a join work between organizational communication and social responsibility no as a panacea or a definite response to all the difficulties, but as an option of organizational success primarily focused on the reinforcement of internal processes and projecting that success externally. in order to give this idea an appropriate context, a journey going through the variety of situations that have had to be surpassed by organizations, given the fact that the external projection understood as competitiveness has made companies make changes in their productivity and, therefore, in their internal processes. those changes and demands of the market have been taking place during the last decades and still require efforts and bring difficulties. the proposal suggests that it is not enough to make social responsibility. it has to be communicated and that communication must not be only external, as it has been so far, but internal, involving those stakeholders who are inside the organization, as a priority. this brings a priceless number of benefits that go beyond productivity such as sense of belonging, commitment, motivation, satisfaction and teamwork, among others.
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