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Search Results: 1 - 10 of 200768 matches for " P. Subedi "
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Monitoring of Gyps species vulture in Nawalparasi district, Nepal
P Subedi
Banko Janakari , 2008, DOI: 10.3126/banko.v18i2.2171
Abstract: Critically endangered White-rumped vulture (WRV), Gyps bengalensis and Slender-billed vulture (SBV), Gyps tenuirostris monitoring was conducted in Nawalparasi district in the winter of 2005 following Postupalsky criterion. The objectives of this study were to identify and monitor nest localities, behaviour and to explore information about the vultures. A total of 48 Gyps vulture nest was located at six colonies. Of these nests, 18 were found to be active nets, six nests belonged to SBV and 12 nests belonged to WRV. Hundred percent nestling successes were observed in the study area. Restricted pesticides i.e. BHC and DDT were found used in this area. Diclofenac was the commonly used veterinary drug in the treatment of livestock. Carcasses disposal practice was found favorable to the vulture's survival. Gyps vulture richness found in this area is due to the availability of food i.e. floating carcass along the edge of the Narayani river and suitable habitat for roosting and nesting. The majority of the respondents had found favorable attitude towards vulture conservation. Further studies on Gyps vulture to identify the breeding status, head droppings behavior as well as conservation awareness program for local people and school children are recommended for long-term survival of these lords of the sky in the study area.
Defining Molecular Phenotypes of Mesenchymal and hematopoietic Stem Cells derived from Peripheral blood of Acute Lymphocytic Leukemia patients for regenerative stem cell therapy
Pravin D. Potdar,Rambhadur P Subedi
Journal of Stem Cells and Regenerative Medicine , 2011,
Abstract: Acute Lymphocytic Leukemia (ALL) is a clonal myeloid disorder affecting all age groups, characterized by accumulation of immature blast cells in bone marrow and in peripheral blood. Autologous Bone Marrow Transplantation is a present treatment for cure of ALL patients, which is very expensive, invasive process and may have possibility of transplantation of malignant stem cells to patients. In the present study, we hypothesized to isolate large number of normal Mesenchymal & Hematopoietic stem cells from peripheral blood of ALL patients, which will be further characterized for their normal phenotypes by using specific molecular stem cell markers. This is the first study, which defines the existing phenotypes of isolated MSCs and HSCs from peripheral blood of ALL patients. We have established three cell lines in which two were Mesenchymal stem cells designated as MSCALL and MSCnsALL and one was suspension cell line designated as HSCALL. The HSCALL cell line was developed from the lymphocyte like cells secreted by MSCALL cells. Our study also showed that MSCALL from peripheral blood of ALL patient secreted hematopoietic stem cells in vitro culture. We have characterized all three-cell lines by 14 specific stem cell molecular markers. It was found that both MSC cell lines expressed CD105, CD13, and CD73 with mixed expression of CD34 and CD45 at early passage whereas, HSCALL cell line expressed prominent feature of hematopoietic stem cells such as CD34 and CD45 with mild expression of CD105 and CD13. All three-cell lines expressed LIF, OCT4, NANOG, SOX2, IL6, and DAPK. These cells mildly expressed COX2 and did not express BCR-ABL. Overall it was shown that isolated MSCs and HSCs can be use as a model system to study the mechanism of leukemia at stem cell level and their use in stem cell regeneration therapy for Acute Lymphocytic Leukemia.
Tourism Development in Upper Manang Valley of Annapurna Region
Bhim P Subedi,Prem Sagar Chapagain
Nepal Tourism and Development Review , 2011, DOI: 10.3126/ntdr.v1i1.7370
Abstract: The Context: People have traveled throughout history as they have moved from one place to another for various reasons. However, as a business and as guided by individual and group’s voluntary activity, it flourished after the second half of the 20th century, especially after the Second World War. Nepal followed a similar pattern as it was opened for outsiders only after 1950. Since then Nepal’s natural beauty within various ecological zones and its rich cultural heritage have attracted large number of tourists annually from around the world and particularly from Western Europe. DOI: http://dx.doi.org/10.3126/ntdr.v1i1.7370 Nepal Tourism and Development Review Vol.1(1) 2011 56-68
Investigation of Proton-Proton Short-Range Correlations via the 12C(e,e'pp) Reaction
R. Shneor,P. Monaghan,R. Subedi
Physics , 2007, DOI: 10.1103/PhysRevLett.99.072501
Abstract: We investigated simultaneously the 12C(e,e'p) and 12C(e,e'pp) reactions at Q2 = 2 [GeV/c]2, x_B = 1.2, and in an (e,e'p) missing-momentum range from 300 to 600 MeV/c. At these kinematics, with a missing-momentum greater than the Fermi momentum of nucleons in a nucleus and far from the delta excitation, short-range nucleon-nucleon correlations are predicted to dominate the reaction. For(9.5 +/- 2)% of the 12C(e,e'p) events, a recoiling partner proton was observed back-to-back to the 12C(e,e'p) missing momentum vector, an experimental signature of correlations.
Constrained Optimization for a Subset of the Gaussian Parsimonious Clustering Models
Ryan P. Browne,Sanjeena Subedi,Paul McNicholas
Statistics , 2013,
Abstract: The expectation-maximization (EM) algorithm is an iterative method for finding maximum likelihood estimates when data are incomplete or are treated as being incomplete. The EM algorithm and its variants are commonly used for parameter estimation in applications of mixture models for clustering and classification. This despite the fact that even the Gaussian mixture model likelihood surface contains many local maxima and is singularity riddled. Previous work has focused on circumventing this problem by constraining the smallest eigenvalue of the component covariance matrices. In this paper, we consider constraining the smallest eigenvalue, the largest eigenvalue, and both the smallest and largest within the family setting. Specifically, a subset of the GPCM family is considered for model-based clustering, where we use a re-parameterized version of the famous eigenvalue decomposition of the component covariance matrices. Our approach is illustrated using various experiments with simulated and real data.
Variation in Stomatal Characteristics of Bursera simaruba (L.) Sarg., a Dominant Tree Species of Tropical Hardwood Hammock Forest across a Habitat Gradient in the Florida Keys  [PDF]
Suresh C. Subedi, Michael S. Ross, Rosario Vidales, Jay P. Sah, Leonel Sternberg
American Journal of Plant Sciences (AJPS) , 2018, DOI: 10.4236/ajps.2018.910154
Abstract: Tree species in coastal forests may exhibit specialization or plasticity in coping with drought through changes in their stomatal morphology or activity, allowing for a balance between gas exchange and water loss in a periodically stressful environment. To examine these responses, we sought to answer two primary research questions: a) how is variation in B. simaruba’s stomatal traits partitioned across hierarchical levels, i.e., site, tree, and leaf; and b) is variation in stomatal traits an integrated response to physiological stress expressed across the habitat gradient of Florida Keys forests? At eight sites distributed throughout the Keys, five leaves were collected from three mature trees for stomatal analysis. Leaf carbon stable isotope ratio (δ13C) was determined to infer the changes in water use efficiency caused by physiological stress experienced by each tree. The results showed that substantial proportions of the total variance in three traits (stomatal density, stomatal size, and δ13C) were observed at all levels, suggesting that processes operating at each scale are important in determining trait values. A significant negative correlation between stomatal density and size across scales was observed. Path model analysis showed that environmental variables, distance to ground water and ground water salinity, affect leaf δ
Some Common Fixed Point Theorems for Four Mappings in Dislocated Metric Space  [PDF]
Dinesh Panthi, Kumar Subedi
Advances in Pure Mathematics (APM) , 2016, DOI: 10.4236/apm.2016.610057
Abstract: In this article, we establish some common fixed point theorems for two pairs of weakly compatible mappings with (E. A.) and (CLR) property in dislocated metric space which generalize and extend some similar results in the literature.
Rising rate of cesarean section - a year review
Shanti Subedi
Journal of Nobel Medical College , 2011, DOI: 10.3126/jonmc.v1i2.7303
Abstract: Caesarean section is one of the most common surgeries performed in modern obstetrics. The rising trend of caesarean section in modern obstetrics is a major concern in health care system all over the world. With all the limited health care resources in a developing country like Nepal, this rising trend definitely has major implication. Rates of caesarean section countries in many countries have increased beyond the recommended level (WHO, 1985). Current available data from developed countries revealed morbidity and mortality from CS is more than in vaginal delivery for both the mother and fetus. Thus this study was conducted to evaluate the rate and indication for CS and to identify the measures to decrease its incidence if possible. Our results shows the foetal distress as the most common indication for Cesarean section in a eastern part of Nepal, which can be minimized significantly if a proper and timely investigation is carried out. DOI: http://dx.doi.org/10.3126/jonmc.v1i2.7303 Journal of Nobel Medical College (2012), Vol.1 No.2 p.72-76
Suicide – Let’s take necessary steps to prevent it
S Subedi
Journal of Psychiatrists' Association of Nepal , 2014, DOI: 10.3126/jpan.v3i1.11344
Abstract: No Abstract DOI: http://dx.doi.org/10.3126/jpan.v3i1.11344 J Psychiatrists’ Association of Nepal Vol .3, No.1, 2014: 1-2
Aromatic Plant Trade and Livelihood Strategies in Rural Nepal: A Case of Wintergreen in Dolakha District
Madhusudan Subedi
Occasional Papers in Sociology and Anthropology , 2009, DOI: 10.3126/opsa.v11i0.3032
Abstract: The objective of this paper is to assess opportunities for Wintergreen, a natural product's intervention on poverty reduction, strengthening local governance, and improving resource management. DOI: 10.3126/opsa.v11i0.3032 Occasional Papers in Sociology and Anthropology Vol.11 2009 84-103
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