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Search Results: 1 - 10 of 200693 matches for " P. Kostka "
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Microwave-Circuit Optimization with Parallel Enhanced Fast Messy Genetic Algorithm (pefmGA)
P. Kostka,Z. Skvor
Radioengineering , 2003,
Abstract: Fast messy genetic optimization is found suitable for complexmicrowave circuit design. Increase in computation speed is achievedusing several ordinary computers connected to a network. Calculationsare running on background so that computers can be used for otherpurposes at the same time. Dynamic change of bounds, search spacesegmentation and gradient incorporation have significantly improvedconvergence rate. The new method has found global minimum in each run,while classic methods failed for some starting points.
Frequency dependence of the self-heating effect in polymer-based composites
A. Katunin,W. Hufenbach,P. Kostka,K. Holeczek
Journal of Achievements in Materials and Manufacturing Engineering , 2010,
Abstract: Purpose: The self-heating effect caused by viscous energy dissipation in polymer-based composite structures subjected to harmonic loads is considered to have a great influence on the residual life of the component. The purpose of the conducted investigations is the determination of the dynamic mechanical behaviour of a polymer-based composite material under different excitation frequencies and temperatures.Design/methodology/approach: The dynamic mechanical analysis was employed for measurements of temperature and frequency dependence of the complex rigidity parameters. Obtained loss rigidity curves for different load frequencies enable the determination of the glass-transition temperatures and finally frequency-dependence of the loss rigidity determined on the basis of the kinetic molecular theory and Williams-Landel-Ferry (WLF) hypothesis.Findings: The dependency between glass-transition temperature and excitation frequency has been investigated. The activation energy of the phase transition as well as the temperature dependence of the shift factor was calculated. The glass-transition temperature and constants of WLF equation enable the determination of temperature and frequency dependence of the loss rigidity according to the time-temperature superposition principle.Research limitations/implications: The ranges of temperatures were limited to 30-150 °C and excitation frequencies to 1-200 Hz, the behaviour of the composite material outside these ranges can be estimated based on the theoretical assumptions only. Obtained dependencies are correct only for linearly viscoelastic materials.Practical implications: Obtained dependencies can be useful for estimation of the mechanical and thermal degradation of polymer-based composites and can be subsequently applied for the determination of fatigue, crack growth and residual life of composite structures.Originality/value: The determination of temperature and frequency dependence of the loss rigidity gives an opportunity to obtain the self-heating temperature distribution of the polymer-based composite structures under harmonic loading.
Extended proof of fibre-reinforced laminates with holes
L. Kroll,P. Kostka,M. Lepper,W. Hufenbach
Journal of Achievements in Materials and Manufacturing Engineering , 2009,
Abstract: Purpose: A calculation method for the strength prediction of tensioned laminated plates with circular notches is presented.Design/methodology/approach: An extensive basis of experimental data from tensile fracture tests on carbon fibre reinforced specimens with circular notches was used to analyse factors determining the notched strength. The proposed extension of the known Whitney-Nuismer and Karlak Point Stress Criteria improves the strength prediction accuracy through introduction of a special coefficient function that takes into account the dependence between stress gradients in the notch near-field and the distance of the outer boundary.Findings: It was found that the theoretical, notch size and outer boundary independent stress concentration factor is not sufficient for a reliable prediction of the notched strength. The presented results show that calculation procedure based on fundamental mechanical relations of the elasticity theory with few experimentally determined factors delivers results which good agree with experiments.Research limitations/implications: The calculation procedure was verified on the representative population of tensile specimens made of several types of carbon fibre reinforced laminates used in the aerospace industry.Practical implications: As openings represent relevant sites of failure in the construction, an accurate calculation of the notched strength is essential for the lightweight-oriented design of fibre-reinforced elements. The presented procedure is relevant for construction of practically important tensioned elements with circular holes.Originality/value: The presented formulation of the phenomenological “characteristic distance” concept and its thorough experimental verification is original.
r-Java 2.0: the astrophysics
M. Kostka,N. Koning,Z. Shand,R. Ouyed,P. Jaikumar
Physics , 2014,
Abstract: [Context:] This article is the second in a two part series introducing r-Java 2.0, a nucleosynthesis code for open use that performs r-process calculations and provides a suite of other analysis tools. [Aims:] The first paper discussed the nuclear physics inherent to r-Java 2.0 and in this article the astrophysics incorporated into the software will be detailed. [Methods:] R-Java 2.0 allows the user to specify the density and temperature evolution for an r-process simulation. Defining how the physical parameters (temperature and density) evolve can effectively simulate the astrophysical conditions for the r-process. Within r-Java 2.0 the user has the option to select astrophysical environments which have unique sets of input parameters available for the user to adjust. In this work we study three proposed r-process sites; neutrino-driven winds around a proto-neutron star, ejecta from a neutron star merger and ejecta from a quark nova. The underlying physics that define the temperature and density evolution for each site is described in this work. [Results:] In this paper a survey of the available parameters for each astrophysical site is undertaken and the effect on final r-process abundance is compared. The resulting abundances for each site are also compared to solar observations both independently and in concert. R-Java 2.0 is available for download from the website of the Quark-Nova Project: http://quarknova.ucalgary.ca/
r-Java 2.0: the nuclear physics
M. Kostka,N. Koning,Z. Shand,R. Ouyed,P. Jaikumar
Physics , 2014, DOI: 10.1051/0004-6361/201322887
Abstract: [Aims:] We present r-Java 2.0, a nucleosynthesis code for open use that performs r-process calculations as well as a suite of other analysis tools. [Methods:] Equipped with a straightforward graphical user interface, r-Java 2.0 is capable of; simulating nuclear statistical equilibrium (NSE), calculating r-process abundances for a wide range of input parameters and astrophysical environments, computing the mass fragmentation from neutron-induced fission as well as the study of individual nucleosynthesis processes. [Results:] In this paper we discuss enhancements made to this version of r-Java, paramount of which is the ability to solve the full reaction network. The sophisticated fission methodology incorporated into r-Java 2.0 which includes three fission channels (beta-delayed, neutron-induced and spontaneous fission) as well as computation of the mass fragmentation is compared to the upper limit on mass fission approximation. The effects of including beta-delayed neutron emission on r-process yield is studied. The role of coulomb interactions in NSE abundances is shown to be significant, supporting previous findings. A comparative analysis was undertaken during the development of r-Java 2.0 whereby we reproduced the results found in literature from three other r-process codes. This code is capable of simulating the physical environment of; the high-entropy wind around a proto-neutron star, the ejecta from a neutron star merger or the relativistic ejecta from a quark nova. As well the users of r-Java 2.0 are given the freedom to define a custom environment. This software provides an even platform for comparison of different proposed r-process sites and is available for download from the website of the Quark-Nova Project: http://quarknova.ucalgary.ca/
Sneutrino Hybrid Inflation and Nonthermal Leptogenesis
Stefan Antusch,Jochen P. Baumann,Valerie F. Domcke,Philipp M. Kostka
Physics , 2010, DOI: 10.1088/1475-7516/2010/10/006
Abstract: In sneutrino hybrid inflation the superpartner of one of the right-handed neutrinos involved in the seesaw mechanism plays the role of the inflaton field. It obtains its large mass after the "waterfall" phase transition which ends hybrid inflation. After this phase transition the oscillations of the sneutrino inflaton field may dominate the universe and efficiently produce the baryon asymmetry of the universe via nonthermal leptogenesis. We investigate the conditions under which inflation, with primordial perturbations in accordance with the latest WMAP results, as well as successful nonthermal leptogenesis can be realized simultaneously within the sneutrino hybrid inflation scenario. We point out which requirements successful inflation and leptogenesis impose on the seesaw parameters, i.e. on the Yukawa couplings and the mass of the right-handed (s)neutrino, and derive the predictions for the CMB observables in terms of the right-handed (s)neutrino mass and the other relevant model parameters.
Microarray Based Diagnosis Profits from Better Documentation of Gene Expression Signatures
Dennis Kostka ,Rainer Spang
PLOS Computational Biology , 2008, DOI: 10.1371/journal.pcbi.0040022
Abstract: Microarray gene expression signatures hold great promise to improve diagnosis and prognosis of disease. However, current documentation standards of such signatures do not allow for an unambiguous application to study-external patients. This hinders independent evaluation, effectively delaying the use of signatures in clinical practice. Data from eight publicly available clinical microarray studies were analyzed and the consistency of study-internal with study-external diagnoses was evaluated. Study-external classifications were based on documented information only. Documenting a signature is conceptually different from reporting a list of genes. We show that even the exact quantitative specification of a classification rule alone does not define a signature unambiguously. We found that discrepancy between study-internal and study-external diagnoses can be as frequent as 30% (worst case) and 18% (median). By using the proposed documentation by value strategy, which documents quantitative preprocessing information, the median discrepancy was reduced to 1%. The process of evaluating microarray gene expression diagnostic signatures and bringing them to clinical practice can be substantially improved and made more reliable by better documentation of the signatures.
Gauge Non-Singlet Inflation in SUSY GUTs
Stefan Antusch,Mar Bastero-Gil,Jochen P. Baumann,Koushik Dutta,Steve F. King,Philipp M. Kostka
Physics , 2010, DOI: 10.1007/JHEP08(2010)100
Abstract: We explore the novel possibility that the inflaton responsible for cosmological inflation is a gauge non-singlet in supersymmetric (SUSY) Grand Unified Theories (GUTs). For definiteness we consider SUSY hybrid inflation where we show that the scalar components of gauge non-singlet superfields, together with fields in conjugate representations, may form a D-flat direction suitable for inflation. We apply these ideas to SUSY models with an Abelian gauge group, a Pati-Salam gauge group and finally Grand Unified Theories based on SO(10) where the scalar components of the matter superfields in the $\sixteen$s may combine with a single $\bar {sixteen}$ to form the inflaton, with the right-handed sneutrino direction providing a possible viable trajectory for inflation. Assuming sneutrino inflation, we calculate the one-loop Coleman-Weinberg corrections and the two-loop corrections from gauge interactions giving rise to the "gauge \eta-problem" and show that both corrections do not spoil inflation, and the monopole problem can be resolved. The usual \eta-problem arising from supergravity may also be resolved using a Heisenberg symmetry.
Modeling DNA methylation dynamics with approaches from phylogenetics
John A. Capra,Dennis Kostka
Quantitative Biology , 2014, DOI: 10.1093/bioinformatics/btu445
Abstract: Methylation of CpG dinucleotides is a prevalent epigenetic modification that is required for proper development in vertebrates, and changes in CpG methylation are essential to cellular differentiation. Genome-wide DNA methylation assays have become increasingly common, and recently distinct stages across differentiating cellular lineages have been assayed. How- ever, current methods for modeling methylation dynamics do not account for the dependency structure between precursor and dependent cell types. We developed a continuous-time Markov chain approach, based on the observation that changes in methylation state over tissue differentiation can be modeled similarly to DNA nucleotide changes over evolutionary time. This model explicitly takes precursor to descendant relationships into account and enables inference of CpG methylation dynamics. To illustrate our method, we analyzed a high-resolution methylation map of the differentiation of mouse stem cells into several blood cell types. Our model can successfully infer unobserved CpG methylation states from observations at the same sites in related cell types (90% correct), and this approach more accurately reconstructs missing data than imputation based on neighboring CpGs (84% correct). Additionally, the single CpG resolution of our methylation dynamics estimates enabled us to show that DNA sequence context of CpG sites is informative about methylation dynamics across tissue differentiation. Finally, we identified genomic regions with clusters of highly dynamic CpGs and present a likely functional example. Our work establishes a framework for inference and modeling that is well-suited to DNA methylation data, and our success suggests that other methods for analyzing DNA nucleotide substitutions will also translate to the modeling of epigenetic phenomena.
Tribrid Inflation in Supergravity
Stefan Antusch,Koushik Dutta,Philipp M. Kostka
Physics , 2009, DOI: 10.1063/1.3327524
Abstract: We propose a novel class of F-term hybrid inflation models in supergravity (SUGRA) where the $\eta$-problem is resolved using either a Heisenberg symmetry or a shift symmetry of the Kaehler potential. In addition to the inflaton and the waterfall field, this class (referred to as tribrid inflation) contains a third 'driving' field which contributes the large vacuum energy during inflation by its F-term. In contrast to the ''standard'' hybrid scenario, it has several attractive features due to the property of vanishing inflationary superpotential (W_inf=0) during inflation. While the symmetries of the Kaehler potential ensure a flat inflaton potential at tree-level, quantum corrections induced by symmetry breaking terms in the superpotential generate a slope of the potential and lead to a spectral tilt consistent with recent WMAP observations.
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