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Search Results: 1 - 10 of 111801 matches for " Oyetayo O. Jeje "
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The Pathways to the First Contact with Mental Health Services among Patients with Schizophrenia in Lagos, Nigeria
Increase Ibukun Adeosun,Abosede Adekeji Adegbohun,Tomilola Adejoke Adewumi,Oyetayo O. Jeje
Schizophrenia Research and Treatment , 2013, DOI: 10.1155/2013/769161
Abstract: There is increasing evidence that delay in the commencement of treatment, following the onset of schizophrenia, may be related to the pathways patients navigate before accessing mental health care. Therefore, insight into the pattern and correlates of pathways to mental care of patients with schizophrenia may inform interventions that could fast track their contact with mental health professionals and reduce the duration of untreated psychosis. This study assessed the pathways to mental health care among patients with schizophrenia ( ), at their first contact with mental health services at the Federal Neuro-Psychiatric Hospital Yaba Lagos, Nigeria. Traditional and religious healers were the first contact for the majority (69%) of the patients. Service users who first contacted nonorthodox healers made a greater number of contacts in the course of seeking help, eventuating in a longer duration of untreated psychosis ( ). However, the delay between the onset of psychosis and contact with the first point of care was shorter in patients who patronized nonorthodox practitioners. The findings suggest that collaboration between orthodox and nonorthodox health services could facilitate the contact of patients with schizophrenia with appropriate treatment, thereby reducing the duration of untreated psychosis. The need for public mental health education is also indicated. 1. Introduction Schizophrenia is a severe, chronic, disabling mental disorder, with a lifetime morbid risk of about 1%, and a leading contributor to the global burden of diseases [1]. Despite the availability of effective therapy, there is a huge treatment gap for schizophrenia, with more than 40 million affected people in need of treatment in low and middle income countries [2–4]. Systematic reviews and meta-analytic studies have shown that delay in the commencement of appropriate treatment following the onset of psychosis is associated with more severe symptom profile, worse psychosocial functioning, poorer quality of life, and poorer treatment outcomes in patients with schizophrenia [5, 6]. Efforts at reducing the lag in the initiation of treatment for first episode schizophrenia has led to an increasing research interest in the pathways through which people with the disorders access care, with the view of identifying points of delay and, consequently, potential loci of interventions that could minimize the delay. Pathways to care refer to the sequence of contacts an ailing person makes with services provided by individuals or organisations, prompted by the effort of the distressed persons
Symptom Profile and Severity in a Sample of Nigerians with Psychotic versus Nonpsychotic Major Depression
Increase Ibukun Adeosun,Oyetayo Jeje
Depression Research and Treatment , 2013, DOI: 10.1155/2013/815456
Abstract: The therapeutic strategies in managing patients with psychotic major depression (PMD) differ from those with non-psychotic major depression (NMD), because of differences in clinical profile and outcome. However, there is underrecognition of psychotic symptoms in depressed patients. Previous studies in Western population suggest that certain symptom patterns, apart from psychosis which may be concealed, can facilitate the discrimination of PMD from NMD. These studies may have limited applicability to sub-Saharan Africa due to cross-cultural differences in the phenomenology of depression. This study compared the rates and severity of depressive symptoms in outpatients with PMD ( ) and NMD ( ) using the Structured Clinical Interview for Depression (SCID) and Hamilton Depression Rating Scale (HAM-D). Patients with PMD had statistically significantly higher rates of suicidal ideation, suicidal attempt, psychomotor agitation, insomnia, and reduced appetite. Patients with NMD were more likely to manifest psychomotor retardation and somatic symptoms. PMD was associated with greater symptom severity. On logistic regression analysis, suicidal ideation, psychomotor disturbances, insomnia, and somatic symptoms were predictive of diagnostic status. The presence of these symptoms clusters may increase the suspicion of occult psychosis in patients with depression, thereby informing appropriate intervention strategies. 1. Introduction Depression is a common psychiatric disorder estimated to affect about 1 out of 5 people in their lifetime [1]. It is a leading cause of disability, projected to become the second leading contributor to the global burden of disease by the year 2020 [2]. Clinically, a major depressive episode or disorder is characterised by the presence of depressed mood, loss of interest, low energy, and significant changes in sleep, appetite, weight, and psychomotor activity. Other symptoms include indecisiveness, feelings of worthlessness, guilt, and suicidality [3, 4]. Epidemiological evidence indicates that about 19 to 25% of patients with major depression have psychotic symptoms, typically delusions and hallucinations [5]. In comparison to Nonpsychotic major depression (NMD), patients with psychotic major depression (PMD) have a worse clinical course characterised by higher rates of recurrence, treatment resistance, suicidality, psychosocial impairment, overall symptom severity, and comorbidity [6–9]. Research has shown that there is underdetection of psychotic symptoms in depressed patients because psychotic symptoms may be subtle, intermittent,
Analysis of Financial Risk Management Strategies of Microfinance Banks  [PDF]
O. J. Oyetayo, S. U. Eboigbe
Journal of Financial Risk Management (JFRM) , 2018, DOI: 10.4236/jfrm.2018.73015
Abstract: Risk taking is described as an integral part of financial services. For micro-financing in particular, engaging in proactive risk taking is essential to their viability and long term sustainability. Maintaining a good strategy that ensures an optimal mix in risk-return trade-off is much more important for the microfinance banks (MFBs) that operate on a for-profit basis. Having faulted the value-at-risk technique which is common in the asset and liability literature, we introduce the multi-stage stochastic programming using econometric time series model. Specifically, for the scenario generation, we specify a VaR model with the inclusion of dichotomy regime which captures the multi-stage characteristics of assets. We use the liability derived investment (LDI) model to generate the liability series over the period of study. The optimization result showed that MFBs in Nigeria are by far more risk averse than they are profit seeking. This comes with the attendant effect of not being able to achieve the outreach and sustainability objectives to the fullest. MFBs in Nigeria need to look into their investment strategy with a view to structuring the mix and value of the balance sheet components at different periods to meet their stated objectives.
Free radical scavenging and antimicrobial properties of extracts of wild mushrooms
Oyetayo, V.O.;
Brazilian Journal of Microbiology , 2009, DOI: 10.1590/S1517-83822009000200031
Abstract: antioxidant and antimicrobial potentials of extracts obtained from four wild mushrooms, termitomyces clypeatus (tce), termitomyces robustus (tre), lentinus subnudus (lse) and lenzites species (lze) collected in nigeria were investigated. lse and lze displayed good scavenging activity against 2, 2-diphenyl-1-picrylhydrazyl (dpph) and ferrous ion radicals at concentration of 2 mg/ml. however, tre and tce exhibited better superoxide anion scavenging effect at 2 mg/ml. all extracts (tce, tre, lse and lze) had comparable scavenging effect on hydroxyl radicals as butylated hydroxytoluene (bht) used as control. moreover, extracts from the wild mushrooms were able to inhibit the growth of all indicator organisms at concentrations between 12.5 mg/ml to 100 mg/ml. lse and lze, however, showed better antimicrobial effect on the indicator organisms. the results suggest that extracts obtained from the four wild mushrooms may serve as sources of new bioactive compounds with effective antioxidant and antimicrobial activity.
Preliminary Study of the Health Promoting Potentials of Lactobacillus Fermentum OVL and Plerotus Sajor caju Administered to Rats
V.O. Oyetayo,F.L. Oyetayo
Pakistan Journal of Nutrition , 2005,
Abstract: Preliminary in vivo study of the potential synergy of health promoting ability of Lactobacillus fermentum OVL and edible mushroom, Plerotus sajor-caju, was investigated in rats (Rattus norvegicus). From the results obtained, there was no obvious potential synergy between Lactobacillus fermentum OVL and Plerotus sajor-caju in promoting the growth performance of rats dosed with Lactobacillus fermentum OVL and placed on diet compounded from the mushroom, Plerotus sajor-caju (MDL). The daily weight gain (DWG), feed conversion ratio (FCR), and protein efficiency ratio (PER) were better in control (PD) placed on diet compounded with casein than in diet compounded from mushroom (MD and MDL). However, there were obvious potential synergy between Lactobacillus fermentum OVL and Plerotus sajor-caju in stimulating the immune response of the host. The serum globulin in treatment MD and MDL (38.33mg/dl and 46.87mg/dl respectively) were higher and significantly different (P<0.05) from control (PD). There was also a potential synergy in the ability of Lactobacillus fermentum OVL and Plerotus sajor-caju in bringing about an increase in the count of beneficial lactobacilli in the faeces of rats in treatments MD and MDL having faecal lactobacilli count of 6.81 cfu/g and 7.32 cfu/g respectively when compared with control (PD) with 6.66 cfu/g that was lower and significantly different (P<0.05).
Evaluation of the Cash Flow Policies and its Effect on the Completion Time of Projects in Western Nigeria
O.O. Amu,J.O. Jeje
Journal of Applied Sciences , 2005,
Abstract: This study evaluates the cash flow policies and its effect on the completion time of projects in western Nigeria. It was observed that 27.4% of the total numbers of sixty-two projects considered were completed within the time frame, while 72.6% were yet to be completed on the agreed time frame. The 73.3% of the yet to be completed projects were due to cash flow problems, that is, lack of subsequent fund after the initial mobilization fees provided by the government for the projects. The other 11.1, 13.3 and 2.2% were delays due to the lack of mobilization fees, equipment breakdowns and poor weather conditions respectively. The major constraints to the timely completion of projects in the western states considered therefore, were due to cash flow problems.
Proton Pump Inhibitors and the Prevention of Recurrent GI Bleed in Patients Treated with Clopidogrel
O.O. Oyetayo, C.A. Farris and J. Wahawisan
Clinical Medicine Insights: Therapeutics , 2012, DOI: 10.4137/CMT.S7253
Abstract: Clopidogrel is an antiplatelet agent indicated in the management of atherothrombotic conditions. Bleeding is a predictable adverse event associated with antiplatelet agents. While non-ulcerogenic; a major site of bleeding with clopidogrel is the gastrointestinal (GI) tract. The risk of GI bleeding with clopidogrel monotherapy is generally low; however, it increases with the presence of other risk factors such as aspirin use, advanced age, prior GI bleed, non-steroidal anti-inflammatory drugs, steroids and anticoagulants. In patients with a prior GI bleed, the risk of recurrence is high and strategies to prophylactically mitigate the risk should be implemented. In this review, evidence supporting the use of proton pump inhibitors to reduce the risk of recurrent GI bleed is discussed. Recommendations on an appropriate regimen to diminish the risk are provided.
Proton Pump Inhibitors and the Prevention of Recurrent GI Bleed in Patients Treated with Clopidogrel
O.O. Oyetayo,C.A. Farris,J. Wahawisan
Clinical Medicine Insights: Therapeutics , 2012,
Abstract:
Haematological Studies of Rats Fed Different Doses of Probiotic, Lactobacillus plantarum, Isolated from Fermenting Corn Slurry
F.I. Aboderin,V.O. Oyetayo
Pakistan Journal of Nutrition , 2006,
Abstract: The effect of oral administration of different doses of probiotic, Lactobacillus plantarum, isolated from fermenting corn slurry on the haematological parameters of wistar albino rats was investigated. Sixteen (16) rats divided into four groups (A, B, C and D) of four rats per group were used. Group A was placed on the basal diet alone, while group B, C and D were placed on the diet and also dosed with 0.3ml, 0.6ml, and 1.0ml of 107 cfu/ml of reconstituted lyophilized culture of Lactobacillus plantarum respectively. In rats treated with different doses of Lactobacillus plantarum there was a significant increase in the packed cell volume (PCV), haemoglobin and red blood cell (RBC) when compared with the control. Moreover, the differential leucocyte counts reveal an increase in the lymphocyte count of the rats dosed with Lactobacillus plantarum when compared to the control except in rats dosed with 1.0ml of 107 cfu/ml of the probiotic, which was not significantly different (P<0.05) from the control. There was also a significant increase (P<0.05) in the weight gain by rats fed Lactobacillus plantarum when compared to the control. The data obtained showed that Lactobacillus plantarum isolated from fermenting corn slurry is safe and it has immunostimulatory effect and can also improve the performance of rats in terms of weight gain.
Microbial and Chemical Qualities of Raw and Trona Processed African Breadfruit (Treculia africana Decne)
V.O. Oyetayo,V.C. Omenwa
American Journal of Food Technology , 2006,
Abstract: A comparative study of the microbial and chemical qualities of African breadfruit, Treculia africana Decne raw seed and seed boiled with trona was investigated. There was a significant (p< 0.05) decrease in the viable count of the seed boiled with trona (6.28 cfu g-1) when compared to the raw seed (6.53 cfu g-1). Bacteria isolated from the raw seed include Bacillus sp., Staphylococcus sp. and Micrococcus sp. while in the boiled seed and seed boiled with trona, only Bacillus sp. was isolated. The protein, fibre and ash content of the raw seed sample was significantly (p< 0.05) higher when compared to the boiled seed and seed boiled with trona. The antinutrients viz; phytate, tannin and cyanide of the boiled seed and seed boiled with trona were significantly (p< 0.05) lower when compared to the raw seed. Boiling T. africana seed with trona improve the microbial quality and reduce the antinutrient content, however, the protein, ash and carbohydrate content of the seed boiled trona reduced when compared to the raw seed.
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